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Volumn 42, Issue 3, 1999, Pages 510-514

Novel antitumor 2-cyanoaziridine-1-carboxamides

Author keywords

[No Author keywords available]

Indexed keywords

2 CYANOAZIRIDINE 1 CARBOXAMIDE; ANTINEOPLASTIC AGENT; IMEXON; UNCLASSIFIED DRUG;

EID: 0032972043     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980600x     Document Type: Article
Times cited : (22)

References (33)
  • 3
    • 0002448742 scopus 로고
    • Aziridines
    • Foye, W. O., Ed.; American Chemical Society: Washington, DC
    • Reynolds, R. C. Aziridines. In Cancer Chemotherapeutic Agents; Foye, W. O., Ed.; American Chemical Society: Washington, DC, 1995; pp 186-197.
    • (1995) Cancer Chemotherapeutic Agents , pp. 186-197
    • Reynolds, R.C.1
  • 5
    • 0001806432 scopus 로고
    • Antitumor antibiotics
    • Foye, W. O., Ed.; American Chemical Society: Washington, DC
    • Remers, W. A.; Iyengar, B. S. Antitumor Antibiotics. In Cancer Chemotherapeutic Agents; Foye, W. O., Ed.; American Chemical Society: Washington, DC, 1995; pp 584-592.
    • (1995) Cancer Chemotherapeutic Agents , pp. 584-592
    • Remers, W.A.1    Iyengar, B.S.2
  • 6
    • 0345600920 scopus 로고
    • Immunopharmacological properties of 2-cyanaziridine derivatives
    • Fenical, R. G., Chirigos, M. A., Eds.; Marcel Dekker: New York and Basle
    • Bicker, U. W. Immunopharmacological Properties of 2-Cyanaziridine Derivatives. In Immune Modulation Agents and Their Mechanisms; Fenical, R. G., Chirigos, M. A., Eds.; Marcel Dekker: New York and Basle, 1984; pp 447-473.
    • (1984) Immune Modulation Agents and Their Mechanisms , pp. 447-473
    • Bicker, U.W.1
  • 7
    • 0016671240 scopus 로고
    • N-(2-cyanoethylene)urea - An asparagine analogous cytostatic compound?
    • Bicker, U. N-(2-Cyanoethylene)urea - an Asparagine Analogous Cytostatic Compound? Exp. Pathol. 1975, 10, 106-108.
    • (1975) Exp. Pathol. , vol.10 , pp. 106-108
    • Bicker, U.1
  • 8
    • 0016705766 scopus 로고
    • Carcinostatic action of 2-cyanoaziridines against sarcoma in rats
    • Bicker, U.; Fichse, P. Carcinostatic Action of 2-Cyanoaziridines Against Sarcoma in Rats. Exp. Pathol. 1975, 10, 279-284.
    • (1975) Exp. Pathol. , vol.10 , pp. 279-284
    • Bicker, U.1    Fichse, P.2
  • 11
    • 0017607790 scopus 로고
    • Cancerostatic action of the immune-stimulating compound 4-imino-1,3-diazabicyclo[3.1.0]hexane-2-one, BM 06 002 (proposed INN name imexon) on various transplantation tumors
    • Bicker, U.; Hebold, G. Cancerostatic Action of the Immune-Stimulating Compound 4-imino-1,3-diazabicyclo[3.1.0]hexane-2-one, BM 06 002 (Proposed INN Name Imexon) on Various Transplantation Tumors. IRCS Med. Sci.: Cancer; Hematol. Immunol. Allergy; Pharmacol. 1977, 5, 428.
    • (1977) IRCS Med. Sci.: Cancer; Hematol. Immunol. Allergy; Pharmacol. , vol.5 , pp. 428
    • Bicker, U.1    Hebold, G.2
  • 12
    • 0344738692 scopus 로고
    • Antitumor effects of imexon combined with myelosuppressive and non myelosuppressive anticancer agents
    • Hersh, E. M.; Dorr, R. T.; Curtis, R. A.; Prince, J. E. Antitumor Effects of Imexon Combined with Myelosuppressive and Non Myelosuppressive Anticancer Agents. Proc. Am. Assoc. Cancer Res. 1995, 36, 294.
    • (1995) Proc. Am. Assoc. Cancer Res. , vol.36 , pp. 294
    • Hersh, E.M.1    Dorr, R.T.2    Curtis, R.A.3    Prince, J.E.4
  • 15
    • 0026670849 scopus 로고
    • Antiproliferative and antitumor activity of the 2-cyanoaziridine compound imexon on tumor cell lines and fresh tumor cells in vitro
    • Hersh, E. M.; Gschwind, C. R.; Taylor, C. W.; Dorr, R. T.; Taetle, R.; Salmon, S. E. Antiproliferative and Antitumor Activity of the 2-Cyanoaziridine Compound Imexon on Tumor Cell Lines and Fresh Tumor Cells In Vitro. J. Natl. Cancer Inst. 1992, 84. 1238-1244.
    • (1992) J. Natl. Cancer Inst. , vol.84 , pp. 1238-1244
    • Hersh, E.M.1    Gschwind, C.R.2    Taylor, C.W.3    Dorr, R.T.4    Taetle, R.5    Salmon, S.E.6
  • 20
    • 0026716727 scopus 로고
    • Chemie von aziridinecarbonsäuren; 2. Mitteilung eine einfach synthese von 2-aminopropennitril
    • Jähnisch, J.; Weigt, E.; Bosies, E. Chemie von Aziridinecarbonsäuren; 2. Mitteilung Eine Einfach Synthese von 2-Aminopropennitril. (Chemistry of Aziridinecarboxylic Acids; 2. Note on a Simple Synthesis of 2-Aminopropenenitrile.) Synthesis 1992, 1211-1212.
    • (1992) Synthesis , pp. 1211-1212
    • Jähnisch, J.1    Weigt, E.2    Bosies, E.3
  • 22
    • 0014115428 scopus 로고
    • Production of free light chains of immunoglobulin by a hematopoetic cell line derived from a patient with multiple myeloma
    • Matsuoka, Y.; Moore, G. E.; Yagi, Y.; Pressman, D. Production of Free Light Chains of Immunoglobulin by a Hematopoetic Cell Line Derived from a Patient with Multiple Myeloma. Proc. Soc. Exp. Biol. Med. 1967, 125, 1246-1250.
    • (1967) Proc. Soc. Exp. Biol. Med. , vol.125 , pp. 1246-1250
    • Matsuoka, Y.1    Moore, G.E.2    Yagi, Y.3    Pressman, D.4
  • 23
    • 0021185050 scopus 로고
    • Experimental model systems of ovarian cancer: Applications to the design and evaluation of new treatment approaches
    • Hamilton, T. C.; Young, R. C.; Ozols, R. F. Experimental Model systems of Ovarian Cancer: Applications to the Design and Evaluation of New Treatment Approaches. Semin. Oncol. 1984, 11, 285-298.
    • (1984) Semin. Oncol. , vol.11 , pp. 285-298
    • Hamilton, T.C.1    Young, R.C.2    Ozols, R.F.3
  • 25
    • 0025733402 scopus 로고
    • Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line
    • Taylor, C. W.; Dalton, W. S.; Parrish, P. R.; Gleason, M. C.; Bellamy, W. T.; Thompson, F. H.; Roe, D. J.; Trent, J. M. Different Mechanisms of Decreased Drug Accumulation in Doxorubicin and Mitoxantrone Resistant Variants of the MCF7 Human Breast Cancer Cell Line. Br. J. Cancer 1991, 63, 923-929.
    • (1991) Br. J. Cancer , vol.63 , pp. 923-929
    • Taylor, C.W.1    Dalton, W.S.2    Parrish, P.R.3    Gleason, M.C.4    Bellamy, W.T.5    Thompson, F.H.6    Roe, D.J.7    Trent, J.M.8
  • 26
    • 0028239105 scopus 로고
    • Analysis of MRP mRNA in mitoxantrone-selected, multidurg-resistant human tumor cells
    • Futscher, B. W.; Abbaszadegan, M. R.; Domann, F.; Dalton, W. S. Analysis of MRP mRNA in Mitoxantrone-Selected, Multidurg-Resistant Human Tumor Cells. Biochem. Pharmacol. 1994, 47, 1601-1606.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 1601-1606
    • Futscher, B.W.1    Abbaszadegan, M.R.2    Domann, F.3    Dalton, W.S.4
  • 28
    • 0023897681 scopus 로고
    • Cytogenetic and phenotypic analysis of a human colon carcinoma cell line resistant to mitoxantrone
    • Dalton, W. S.; Cress, A. E.; Alberts, D. S.; Trent, J. M. Cytogenetic and Phenotypic Analysis of a Human Colon Carcinoma Cell Line Resistant to Mitoxantrone. Cancer Res. 1988, 48, 1882-1888.
    • (1988) Cancer Res. , vol.48 , pp. 1882-1888
    • Dalton, W.S.1    Cress, A.E.2    Alberts, D.S.3    Trent, J.M.4
  • 29
    • 0345168887 scopus 로고
    • Evaluation of antileukemic agents employing advanced leukemia L1210 in mice. IV. (Various compounds)
    • Goldin, A.; Venditti, J. M.; Kline, I.; Mantel, N. Evaluation of Antileukemic Agents Employing Advanced Leukemia L1210 in Mice. IV. (Various Compounds). Cancer Res. 1961, 21, 27-92.
    • (1961) Cancer Res. , vol.21 , pp. 27-92
    • Goldin, A.1    Venditti, J.M.2    Kline, I.3    Mantel, N.4
  • 30
    • 0023280679 scopus 로고
    • Mitomycin C resistant L1210 leukemia cells: Association with plieotropic drug resistance
    • Dorr, R. T.; Kiddil, J. D.; Trent, J. M.; Dalton, W. S. Mitomycin C Resistant L1210 Leukemia Cells: Association with Plieotropic Drug Resistance. Biochem. Pharmacol. 1987, 36, 3115-3120.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 3115-3120
    • Dorr, R.T.1    Kiddil, J.D.2    Trent, J.M.3    Dalton, W.S.4
  • 31
    • 0345168881 scopus 로고    scopus 로고
    • Sigmastat 1.0 for Windows is available from Jandel Scientific, 2591 Kerner Blvd, San Rafael, CA 94912-8920
    • Sigmastat 1.0 for Windows is available from Jandel Scientific, 2591 Kerner Blvd, San Rafael, CA 94912-8920.
  • 32
    • 0019808332 scopus 로고
    • Evaluation of new anthracycline analogues with the human tumor stem cell assay
    • Salmon, S. E.; Liu, R.; Casazza, A. M. Evaluation of New Anthracycline Analogues with the Human Tumor Stem Cell Assay. Cancer Chemother. Pharmacol. 1981, 6, 103-109.
    • (1981) Cancer Chemother. Pharmacol. , vol.6 , pp. 103-109
    • Salmon, S.E.1    Liu, R.2    Casazza, A.M.3
  • 33
    • 0027954466 scopus 로고
    • Sensitivity of multiple myeloma to imexon in the human tumor cloning assay
    • Salmon, S. E.; Hersh, E. M. Sensitivity of Multiple Myeloma to Imexon in the Human Tumor Cloning Assay. J. Natl. Cancer Inst. 1994, 86, 228-230.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 228-230
    • Salmon, S.E.1    Hersh, E.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.