First functional characterization of a singly expressed bacterial type II topoisomerase: The enzyme from Mycobacterium tuberculosis

Biochemical and Biophysical Research Communications

Volumn 348, Issue 1, 2006, Pages 158-165

  Aubry, Alexandra ^a   Mark Fisher, L ^b   Jarlier, Vincent ^a   Cambau, Emmanuelle ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Decatenation; DNA gyrase; Mycobacterium tuberculosis; Topoisomerase

Indexed keywords

BACTERIAL DNA; BACTERIAL ENZYME; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; ESCHERICHIA COLI PROTEIN; KINETOPLAST DNA;

ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; GENE EXPRESSION; GENETIC CODE; MOLECULAR CLONING; MOLECULAR DYNAMICS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STREPTOCOCCUS PNEUMONIAE;

DNA GYRASE; DNA TOPOISOMERASE IV; DNA, KINETOPLAST; ENZYME ACTIVATION; ESCHERICHIA COLI; MYCOBACTERIUM TUBERCULOSIS; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; SPECIES SPECIFICITY; STREPTOCOCCUS PNEUMONIAE; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MYCOBACTERIUM TUBERCULOSIS; STREPTOCOCCUS PNEUMONIAE;

EID: 33746819774     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.07.017     Document Type: Article

References (28)

1. Champoux J.J. DNA topoisomerases: structure, function, and mechanism. Annu. Rev. Biochem. 70 (2001) 369-413
2. Corbett K.D., and Berger J.M. Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases. Annu. Rev. Biophys. Biomol. Struct. 33 (2004) 95-118
3. Levine C., Hiasa H., and Marians K.J. DNA gyrase and topoisomerase IV: biochemical activities, physiological roles during chromosome replication, and drug sensitivities. Biochem. Biophys. Acta 1400 (1998) 29-43
4. Corbett K.D., Shultzaberger R.K., and Berger J.M. The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold. Proc. Natl. Acad. Sci. USA 101 (2004) 7293-7298
5. Kato J., Nishimura Y., Imamura R., Niki H., Hiraga S., and Suzuki H. New topoisomerase essential for chromosome segregation in E. coli. Cell 63 (1990) 393-404
6. Peng H., and Marians K.J. Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions. J. Biol. Chem. 268 (1993) 24481-24490
7. Blanche F., Cameron B., Bernard F.X., Maton L., Manse B., Ferrero L., Ratet N., Lecoq C., Goniot A., Bisch D., and Crouzet J. Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases. Antimicrob. Agents Chemother. 40 (1996) 2714-2720
8. Pan X.S., and Fisher L.M. Streptococcus pneumoniae DNA gyrase and topoisomerase IV: overexpression, purification, and differential inhibition by fluoroquinolones. Antimicrob. Agents Chemother. 43 (1999) 1129-1136
9. Huang W.M. Bacterial diversity based on type II DNA topoisomerase genes. Annu. Rev. Genet. 30 (1996) 79-107
10. Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry III C.E., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Barrell B.G., et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393 (1998) 537-544
11. Aubry A., Pan X.S., Fisher L.M., Jarlier V., and Cambau E. Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity. Antimicrob. Agents Chemother. 48 (2004) 1281-1288
12. Revel-Viravau V., Truong Q.C., Moreau N., Jarlier V., and Sougakoff W. Sequence analysis, purification, and study of inhibition by 4-quinolones of the DNA gyrase from Mycobacterium smegmatis. Antimicrob. Agents Chemother. 40 (1996) 2054-2061
13. Guillemin I., Sougakoff W., Cambau E., Revel-Viravau V., Moreau N., and Jarlier V. Purification and inhibition by quinolones of DNA gyrases from Mycobacterium avium, Mycobacterium smegmatis and Mycobacterium fortuitum bv. peregrinum. Microbiology 145 (1999) 2527-2532
14. Madhusudan K., and Nagaraja V. Mycobacterium smegmatis DNA gyrase: cloning and overexpression in Escherichia coli. Microbiology 141 (1995) 3029-3037
15. Wu L.C., and Shahied S.I. Mycobacterial DNA gyrase: enzyme purification and characterization of supercoiling activity. Arch. Biochem. Biophys. 324 (1995) 123-129
16. Saiki A.Y., Shen L.L., Chen C.M., Baranowski J., and Lerner C.G. DNA cleavage activities of Staphylococcus aureus gyrase and topoisomerase IV stimulated by quinolones and 2-pyridones. Antimicrob. Agents Chemother. 43 (1999) 1574-1577
17. Lamour V., Hoermann L., Jeltsch J.M., Oudet P., and Moras D. An open conformation of the Thermus thermophilus gyrase B ATP-binding domain. J. Biol. Chem. 277 (2002) 18947-18953
18. Manjunatha U.H., Dalal M., Chatterji M., Radha D.R., Visweswariah S.S., and Nagaraja V. Functional characterisation of mycobacterial DNA gyrase: an efficient decatenase. Nucleic Acids Res. 30 (2002) 2144-2153
19. Leo E., Gould K.A., Pan X.S., Capranico G., Sanderson M.R., Palumbo M., and Fisher L.M. Novel symmetric and asymmetric DNA scission determinants for Streptococcus pneumoniae topoisomerase IV and gyrase are clustered at the DNA breakage site. J. Biol. Chem. 280 (2005) 14252-14263
20. Marini J.C., Miller K.G., and Englund P.T. Decatenation of kinetoplast DNA by topoisomerases. J. Biol. Chem. 255 (1980) 4976-4979
21. Corbett K.D., Schoeffler A.J., Thomsen N.D., and Berger J.M. The structural basis for substrate specificity in DNA topoisomerase IV. J. Mol. Biol. 351 (2005) 545-561
22. Jain P., and Nagaraja V. An atypical type II topoisomerase from Mycobacterium smegmatis with positive supercoiling activity. Mol. Microbiol. 58 (2005) 1392-1405
23. Qi Y., Pei J., and Grishin N.V. C-terminal domain of gyrase A is predicted to have a beta-propeller structure. Proteins 47 (2002) 258-264
24. Kampranis S.C., and Maxwell A. Conversion of DNA gyrase into a conventional type II topoisomerase. Proc. Natl. Acad. Sci. USA 93 (1996) 14416-14421
25. Roca J. Varying levels of positive and negative supercoiling differently affect the efficiency with which topoisomerase II catenates and decatenates DNA. J. Mol. Biol. 305 (2001) 441-450
26. Heddle J.G., Mitelheiser S., Maxwell A., and Thomson N.H. Nucleotide binding to DNA gyrase causes loss of DNA wrap. J. Mol. Biol. 337 (2004) 597-610
27. Hoshino K., Kitamura A., Morrissey I., Sato K., Kato J., and Ikeda H. Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition. Antimicrob. Agents Chemother. 38 (1994) 2623-2627
28. Costenaro L., Grossmann J.G., Ebel C., and Maxwell A. Small-angle X-ray scattering reveals the solution structure of the full-length DNA gyrase a subunit. Structure (Camb) 13 (2005) 287-296