Sequence analysis, purification, and study of inhibition by 4-quinolones of the DNA gyrase from Mycobacterium smegmatis

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 9, 1996, Pages 2054-2061

  Revel Viravau, Valerie ^a   Truong, Que Chi ^a   Moreau, Nicole ^a   Jarlier, Vincent ^a   Sougakoff, Wladimir ^a,b  

^a SORBONNE UNIVERSITÉ   (France)

^b Laboratoire de Bactériologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); NALIDIXIC ACID; OFLOXACIN; QUINOLINE DERIVATIVE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIBACTERIAL ACTIVITY; ARTICLE; DNA HYBRIDIZATION; ENZYME ACTIVITY; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE AMPLIFICATION; MYCOBACTERIUM SMEGMATIS; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE ANALYSIS;

EID: 9544231792     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.9.2054     Document Type: Article

References (52)

1. Adachi, T., K. Mizuuchi, R. Menzel, and M. Gellert. 1984. DNA sequence and transcription of the region upstream of the E. coli gyrB gene. Nucleic Acids Res. 12:6389-6395.
2. Adachi, T., M. Mizuuchi, E. A. Robinson, E. Appella, M. H. O'Dea, M. Gellert, and K. Mizuuchi. 1987. DNA sequence of the E. coli gyrB gene: application of a new sequencing strategy. Nucleic Acids Res. 15:771-784.
3. Alangaden, G. J., E. K. Manavathu, S. B. Vakulenko, N. M. Zvonok, and S. A. Lerner. 1995. Characterization of fluoroquinolone-resistant mutant strains of Mycobacterium tuberculosis selected in the laboratory and isolated from patients. Antimicrob. Agents Chemother. 39:1700-1703.
4. Bazile, S., N. Moreau, D. Bouzard, and M. Essiz. 1992. Relationships among antibacterial activity, inhibition of DNA gyrase, and intracellular accumulation of 11 fluoroquinolones. Antimicrob. Agents Chemother. 36:2622-2627.
5. Belland, R. J., S. G. Morrison, C. Ison, and W. M. Huang. 1994. Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates. Mol. Microbiol. 14:371-380.
6. Brockbank, S. M. V., and P. T. Barth. 1993. Cloning, sequencing, and expression of the DNA gyrase genes from Staphylococcus aureus. J. Bacteriol. 175:3269-3277.
7. Calcutt, M. J. 1994. Gene organization in the dnaA-gyrA region of the Streptomyces coelicolor chromosome. Gene 151:23-28.
8. Cambau, E., W. Sougakoff, M. Besson, C. Truffot-Pernot, J. Grosset, and V. Jarlier. 1994. Selection of a gyrA mutant of Mycobacterium tuberculosis resistant to fluoroquinolones during treatment with ofloxacin. J. Infect. Dis. 170:479-483.
9. Cambau, E., W. Sougakoff, and V. Jarlier. 1994. Amplification and nucleotide sequence of the quinolone resistance-determining region in the gyrA gene of mycobacteria. FEMS Lett. 116:49-54.
10. Colman, S. D., P.-C. Hu, and K. F. Bott. 1990. Mycoplasma pneumoniae DNA gyrase genes. Mol. Microbiol. 4:1129-1134.
11. Dimri, G. P., and H. K. Das. 1990. Cloning and sequence analysis of gyrA gene of Klebsiella pneumoniae. Nucleic Acids Res. 18:151-156.
12. Dugaiczyk, A., R. Goold, G. diSibio, and R. M. Myers. 1992. Improved sequencing of cosmids using new primers and linearized DNA. Nucleic Acids Res. 20:6421-6422.
13. Fleischmann, R. D., M. D. Adams, O. White, R. A. Clayton, E. F. Kirkness, A. R. Kerlavage, C. J. Bult, J.-F. Tomb, B. A. Dougherty, J. M. Merrick, K. McKenney, G. Sutton, W. FitzHugh, C. A. Fields, J. D. Gocayne, J. D. Scott, R. Shirley, L.-I. Liu, A. Glodek, J. M. Kelley, J. F. Weidman, C. A. Phillips, T. Spriggs, E. Hedblom, M. D. Cotton, T. R. Utterback, M. C. Hanna, D. T. Nguyen, D. M. Saudek, R. C. Brandon, L. D. Fine, J. L. Fritchman, J. L. Fuhrmann, N. S. M. Geoghagen, C. L. Gnehm, L. A. McDonald, K. V. Small, C. M. Fraser, H. O. Smith, and J. C. Venter. 1995. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:496-512.
14. Fraser, C. M., J. D. Gocayne, O. White, M. D. Adams, R. A. Clayton, R. D. Fleischmann, C. J. Bult, A. R. Kerlavage, G. Sutton, J. M. Kelley, J. L. Fritchman, J. F. Weidman, K. V. Small, M. Sandusky, J. L. Fuhrmann, D. T. Nguyen, T. R. Uterback, D. M. Saudek, C. A. Phillips, J. M. Merick, J.-F. Tomb, B. A. Dougherty, K. F. Bott, P.-C. Hu, T. S. Lucier, S. N. Peterson, H. O. Smith, C. A. Hutchison III, and J. C. Venter. 1995. The minimal gene complement of Mycoplasma genitalium. Science 270:397-403.
15. Fujita, M. Q., H. Yoshikawa, and N. Ogasawara. 1989. Structure of the dnaA region of Pseudomonas putida: conservation among three bacteria, Bacillus subtilis, Escherichia coli and P. putida. Mol. Gen. Genet. 215:381-387.
16. Gaal, T., J. Barkei, R. R. Dickson, H. A. deBoer, P. L. deHaseth, H. Alavi, and R. L. Gourse. 1989. Saturation mutagenesis of an Escherichia coli rRNA promoter and initial characterization of promoter variants. J. Bacteriol. 171:4852-4861.
17. Galtier, N., and M. Gouy. 1994. Molecular phylogeny of eubacteria: a new multiple tree analysis method applied to 15 sequence data sets questions the monophyly of Gram-positive bacteria. Res. Microbiol. 145:531-541.
18. Gellert, M., K. Mizuuchi, M. H. O'Dea, and H. A. Nash. 1976. DNA gyrase: an enzyme that introduces superhelical turns into DNA. Proc. Natl. Acad. Sci. USA 73:3872-3876.
19. Grundstein, M., and D. Hogness. 1975. Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. Proc. Natl. Acad. Sci. USA 72:3961-3965.
20. Guillemin, I., E. Cambau, and V. Jarlier. 1995. Sequences of conserved region in the A subunit of DNA gyrase from nine species of the genus Mycobacterium: phylogenetic analysis and implication for intrinsic susceptibility to quinolones. Antimicrob. Agents Chemother. 39:2145-2149.
21. Hallett, P., and A. Maxwell. 1991. Novel quinolone resistance mutations of the Escherichia coli DNA gyrase A protein: enzymatic analysis of the mutant proteins. Antimicrob. Agents Chemother. 35:335-340.
22. Hooper, D. C., and J. S. Wolfson. 1991. Mode of action of the new quinolones: new data. Eur. J. Clin. Microbiol. Infect. Dis. (Special Issue) 10:223-231.
23. Ito, H., H. Yoshida, M. Bogaki-Shonai, T. Niga, H. Hattori, and S. Nakamura. 1994. Quinolone resistance mutations in the DNA gyrase gyrA and gyrB genes of Staphylococcus aureus. Antimicrob. Agents Chemother. 38: 2014-2023.
24. Kureishi, A., J. M. Diver, B. Beckthold, T. Schollaardt, and L. E. Bryan. 1994. Cloning and nucleotide sequence of Pseudomonas aeruginosa DNA gyrase gyrA gene from strain PAO1 and quinolone-resistant clinical isolates. Antimicrob. Agents Chemother. 38:1944-1952.
25. Lugtenberg, B., J. Meyers, R. Peters, P. van der Hoek, and L. van Alphen. 1975. Electrophoretic resolution of the "major" outer membrane protein of Escherichia coli K12 into four bands. FEBS Lett. 58:254-258.
26. Madhusudan, K., and V. Nagaraja. 1995. Mycobacterium smegmatis DNA gyrase: cloning and overexpression in Escherichia coli. Microbiology 141: 3029-3037.
27. Madhusudan, K., V. Ramesh, and V. Nagaraja. 1994. Molecular cloning of gyrA and gyrB genes of Mycobacterium tuberculosis: analysis of nucleotide sequence. Biochem. Mol. Biol. Int. 33:651-660.
28. Margerrison, E. E. C., R. Hopewell, and L. M. Fisher. 1992. Nucleotide sequence of the Staphylococcus aureus gyrB-gyrA locus encoding the DNA gyrase A and B proteins. J. Bacteriol. 174:1596-1603.
29. Moore, R. A., B. Beckthold, S. Wong, A. Kureishi, and L. E. Bryan. 1995. Nucleotide sequence of the gyrA gene and characterization of ciprofloxacin-resistant mutants of Helicobacter pylori. Antimicrob. Agents Chemother. 39:107-111.
30. Moreau, N. J., H. Robaux, L. Baron, and X. Tabary. 1990. Inhibitory effects of quinolones on pro- and eucaryotic DNA topoisomerases I and II. Antimicrob. Agents Chemother. 34:1955-1960.
31. Moriya, S., N. Ogasawara, and H. Yoshikawa. 1985. Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. III. Nucleotide sequence of some 10,000 base pairs in the origin region. Nucleic Acids Res. 13:2251-2265.
32. Munoz, R., M. Bustamante, and A. G. de la Campa. 1995. Ser-127-to-Leu substitution in the DNA gyrase B subunit of Streptoccus pneumoniae is implicated in novobiocin resistance. J. Bacteriol. 177:4166-4170.
33. Orr, E., and W. L. Staudenbauer. 1982. Bacillus subtilis DNA gyrase: purification of subunits and reconstitution of supercoiling activity. J. Bacteriol. 151:524-527.
34. Revel, V., E. Cambau, V. Jarlier, and W. Sougakoff. 1994. Characterization of mutations in Mycobacterium smegmatis involved in resistance to fluoroquinolones. Antimicrob. Agents Chemother. 38:1991-1996.
35. Revel, V., and W. Sougakoff. 1994. Cloning and sequence analysis of a DNA fragment encoding the N-terminal region of GyrA of Mycobacterium smegmatis, abstr. C5, p. 8. In Program and abstracts of the 34th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
36. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
37. Sandler, S. J., B. Chackerian, J. T. Li, and A. J. Clark. 1992. Sequence and complementation analysis of recF genes from Escherichia coli, Salmonella typhimurium, Pseudomonas putida and Bacillus subtilis: evidence for an essential phosphate binding loop. Nucleic Acids Res. 20:839-845.
38. Staudenbauer, W. L., and E. Orr. 1981. DNA gyrase: affinity chromatography on novobiocin-Sepharose and catalytic properties. Nucleic Acids Res. 9:3589-3602.
39. Stein, D. C., R. J. Danaher, and T. M. Cook. 1991. Characterization of a gyrB mutation responsible for low-level nalidixic acid resistance in Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 35:622-626.
40. Strosberg, A. D., L. Camoin, and J. L. Guillaume. 1989. Microsequencing of peptides and proteins. Trends Anal. Chem. 8:292-298.
41. Sutcliffe, J. A., T. D. Gootz, and J. F. Barrett. 1989. Biochemical characteristics and physiological significance of major DNA topoisomerases. Antimicrob. Agents Chemother. 33:2027-2033.
42. Swanberg, S. L., and J. C. Wang. 1987. Cloning and sequencing of the Escherichia coli gyrA gene coding for the A subunit of DNA gyrase. J. Mol. Biol. 197:729-736.
43. Takiff, H. E., L. Salazar, C. Guerrero, W. Philipp, W. M. Huang, B. Kreiswirth, S. T. Cole, W. R. Jacobs, Jr., and A. Telenti. 1994. Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations. Antimicrob. Agents Chemother. 39:773-780.
44. Thiara, A. S., and E. Cundliffe. 1988. Cloning and characterization of a DNA gyrase B gene from Streptomyces sphaeroides that confers resistance to novobiocin. EMBO J. 7:2255-2259.
45. Thiara, A. S., and E. Cundliffe. 1993. Expression and analysis of two gyrB genes from the novobiocin producer, Streptomyces sphaeroides. Mol. Microbiol. 8:495-506.
46. van Soolingen, D., P. W. M. Hermans, P. E. W. de Haas, D. R. Soll, and J. D. A. van Embden. 1991. Occurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of an insertion sequence-dependent DNA polymorphism as a tool in the epidemiology of tuberculosis. J. Clin. Microbiol. 29:2578-2586.
47. Wang, J. C. 1985. DNA topoisomerases. Annu. Rev. Biochem. 54:665-697.
48. Wang, J. C. 1991. DNA topoisomerases: why so many?. J. Biol. Chem. 266:6659-6662.
49. Wang, Y., W. M. Huang, and D. T. Taylor. 1993. Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations. Antimicrob. Agents Chemother. 37:457-463.
50. Wolfson, J. S., and D. C. Hooper. 1985. The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro. Antimicrob. Agents Chemother. 28:581-586.
51. Yoshida, H., M. Bogaki, M. Nakamura, and S. Nakamura. 1990. Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli. Antimicrob. Agents Chemother. 34:1271-1272.
52. Yoshida, H., M. Bogaki, M. Nakamura, L. M. Yamanaka, and S. Nakamura. 1991. Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli. Antimicrob. Agents Chemother. 35:1647-1650.