Functional replacement of the R region of simian immunodeficiency virus-based vectors by heterologous elements

Journal of General Virology

Volumn 87, Issue 8, 2006, Pages 2297-2307

  Brandt, Sabine ^a   Grunwald, Thomas ^a   Lucke, Susann ^a,b   Stang, Alexander ^a   Überla, Klaus ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; GAG PROTEIN; POL PROTEIN; RNA; TRANSACTIVATOR PROTEIN; VIRUS VECTOR;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOPLASM; DNA PACKAGING; GENE DELETION; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLONEY MURINE SARCOMA ONCOVIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION; RNA STABILITY; SIMIAN IMMUNODEFICIENCY VIRUS; STEADY STATE; VIRUS PARTICLE; VIRUS REPLICATION; WESTERN BLOTTING; WILD TYPE;

DNA MUTATIONAL ANALYSIS; GENETIC VECTORS; HIV-1; MOLONEY MURINE LEUKEMIA VIRUS; RECOMBINATION, GENETIC; RNA, VIRAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS ASSEMBLY; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; MOLONEY MURINE SARCOMA VIRUS; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 33746818229     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.81883-0     Document Type: Article

References (51)

1. Adachi, A., Gendelman, H. E., Koenig, S., Folks, T., Willey, R., Rabson, A. & Martin, M. A. (1986). Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol 59, 284-291.
2. Allain, B., Rascle, J.-B., de Rocquigny, H., Roques, B. & Darlix, J.-L. (1998). CIS elements and trans-acting factors required for minus strand DNA transfer during reverse transcription of the genomic RNA of murine leukemia virus. J Mol Biol 277, 225-235.
3. Berkhout, B., Klaver, B. & Das, A. T. (1995a). A conserved hairpin structure predicted for the poly(A) signal of human and simian immunodeficiency viruses. Virology 207, 276-281.
4. Berkhout, B., van Wamel, J. & Klaver, B. (1995b). Requirements for DNA strand transfer during reverse transcription in mutant HIV-1 virions. J Mol Biol 252, 59-69.
5. Berkhout, B., Vastenhouw, N. L., Klasens, B. I. & Huthoff, H. (2001). Structural features in the HIV-1 repeat region facilitate strand transfer during reverse transcription. RNA 7, 1097-1114.
6. Bukovsky, A. A., Song, J.-P. & Naldini, L. (1999). Interaction of human immunodeficiency virus-derived vectors with wild-type virus in transduced cells. J Virol 73, 7087-7092.
7. Chackerian, B., Haigwood, N. L. & Overbaugh, J. (1995). Characterization of a CD4-expressing macaque cell line that can detect virus after a single replication cycle and can be infected by diverse simian immunodeficiency virus isolates. Virology 213, 386-394.
8. Chang, L.-J., McNulty, E. & Martin, M. (1993). Human immunodeficiency viruses containing heterologous enhancer/promoters are replication competent and exhibit different lymphocyte tropisms. J Virol 67, 743-752.
9. Cheslock, S. R., Anderson, J. A., Hwang, C. K., Pathak, V. K. & Hu, W.-S. (2000). Utilization of nonviral sequences for minus-strand DNA transfer and gene reconstitution during retroviral replication. J Virol 74, 9571-9579.
10. Clever, J. L., Eckstein, D. A. & Parslow, T. G. (1999). Genetic dissociation of the encapsidation and reverse transcription functions in the 5′ R region of human immunodeficiency virus type 1. J Virol 73, 101-109.
11. Clever, J. L., Mirandar, D., Jr & Parslow, T. G. (2002). RNA structure and packaging signals in the 5′ leader region of the human immunodeficiency virus type 1 genome. J Virol 76, 12381-12387.
12. Coffin, J. M. (1990). Retroviridae and their replication. in Fields Virology, 2nd edn, vol. 2, pp. 1437-1500. Edited by B. N. Fields & D. M. Knipe. New York: Raven Press.
13. Cullen, B. R. (1992). Mechanism of action of regulatory proteins encoded by complex retroviruses. Microbiol Rev 56, 375-394.
14. Daelemans, D., de Clercq, E. & Vandamme, A.-M. (2000). Control of RNA initiation and elongation at the HIV promoter. AIDS Rev 2, 229-240.
15. Dang, Q. & Hu, W.-S. (2001). Effects of homology length in the repeat region on minus-strand DNA transfer and retroviral replication. J Virol 75, 809-820.
16. Das, A. T., Klaver, B., Klasens, B. I., van Wamel, J. L. & Berkhout, B. (1997). A conserved hairpin motif in the R-U5 region of the human immunodeficiency virus type 1 RNA genome is essential for replication. J Virol 71, 2346-2356.
17. Das, A. T., Klaver, B. & Berkhout, B. (1998). The 5′ and 3′ TAR elements of human immunodeficiency virus exert effects at several points in the virus life cycle. J Virol 72, 9217-9223.
18. DuBridge, R. B., Tang, P., Hsia, H. C., Leong, P.-M., Miller, J. H. & Calos, M. P. (1987). Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. Mol Cell Biol 7, 379-387.
19. Fouchier, R. A., Meyer, B. E., Simon, J. H., Fischer, U. & Malim, M. H. (1997). HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import. EMBO J 16, 4531-4539.
20. Gilboa, E., Mitra, S. W., Goff, S. & Baltimore, D. (1979). A detailed model of reverse transcription and tests of crucial aspects. Cell 18, 93-100.
21. Grunwald, T., Pedersen, F. S., Wagner, R. & Überla, K (2004). Reducing mobilization of simian immunodeficiency virus based vectors by primer complementation. J Gene Med 6, 147-154.
22. Guan, Y., Whitney, J. B., Detorio, M. & Wainberg, M. A. (2001). Construction and in vitro properties of a series of attenuated simian immunodeficiency viruses with all accessory genes deleted. J Virol 75, 4056-4067.
23. Gundlach, B. R., Linhart, H., Dittmer, U. & 7 other authors (1997). Construction, replication, and immunogenic properties of a simian immunodeficiency virus expressing interleukin-2. J Viral 71, 2225-2232.
24. Guntaka, R. V. (1993). Transcription termination and polyadenylation in retroviruses. Microbiol Rev 57, 511-521.
25. Hansen, A. C., Grunwald, T., Lund, A. H., Schmitz, A., Duch, M., Überla, K. & Pedersen, F. S. (2001). Transfer of primer binding site-mutated simian immunodeficiency virus vectors by genetically engineered artificial and hybrid tRNA-like primers. J Virol 75, 4922-4928.
26. Harrich, D., Ulich, C. & Gaynor, R. B. (1996). A critical role for the TAR element in promoting efficient human immunodeficiency virus type 1 reverse transcription. J Virol 70, 4017-4027.
27. Harrich, D., Hooker, C. W. & Parry, E. (2000). The human immunodeficiency virus type 1 TAR RNA upper stem-loop plays distinct roles in reverse transcription and RNA packaging. J Virol 74, 5639-5646.
28. Helga-Maria, C., Hammarskjold, M.-L. & Rekosh, D. (1999). An intact TAR element and cytoplasmic localization are necessary for efficient packaging of human immunodeficiency virus type 1 genomic RNA. J Virol 73, 4127-4135.
29. Klaver, B. & Berkhout, B. (1994). Premature strand transfer by the HIV-1 reverse transcriptase during strong-stop DNA synthesis. Nucleic Acids Res 22, 137-144.
30. Kulpa, D., Topping, R. & Telesnitsky, A. (1997). Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors. EMBO J 16, 856-865.
31. Lee, Y., Kim, M., Han, J., Yeom, K.-H., Lee, S., Beak, S. H. & Kim, V. N. (2004). MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23, 4051-4060.
32. Lobel, L. I. & Goff, S. P. (1985). Reverse transcription of retroviral genomes: mutations in the terminal repeat sequences. J Virol 53, 447-455.
33. Malim, M. H., Hauber, J., Fenrick, R. & Cullen, B. R. (1988). Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes. Nature 335, 181-183.
34. McBride, M. S., Schwartz, M. D. & Panganiban, A. T. (1997). Efficient encapsidation of human immunodeficiency virus type 1 vectors and further characterization of cis elements required for encapsidation. J Virol 71, 4544-4554.
35. Means, R. E., Greenough, T. & Desrosiers, R. C. (1997). Neutralization sensitivity of cell culture-passaged simian immunodeficiency virus. J Virol 71, 7895-7902.
36. Moore, R., Dixon, M., Smith, R., Peters, G. & Dickson, C. (1987). Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol. J Virol 61, 480-490.
37. Ohi, Y. & Clever, J. L. (2000). Sequences in the 5′ and 3′ R elements of human immunodeficiency virus type 1 critical for efficient reverse transcription. J Virol 74, 8324-8334.
38. Patel, J., Wang, S.-W., Izmailova, E. & Aldovini, A. (2003). The simian immunodeficiency virus 5′ untranslated leader sequence plays a role in intracellular viral protein accumulation and in RNA packaging. J Virol 77, 6284-6292.
39. Rabson, A. B. & Graves, B. J. (1997). Synthesis and processing of viral RNA. In Retroviruses, pp. 205-261. Edited by J. M. Coffin, S. H. Hughes & H. E. Varmus. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
40. Ramsey, C. A. & Panganiban, A. T. (1993). Replication of the retroviral terminal repeat sequence during in vivo reverse transcription. J Virol 67, 4114-4121.
41. Schnell, T., Foley, P., Wirth, M., Münch, J. & Überla, K (2000). Development of a self-inactivating, minimal lentivirus vector based on simian immunodeficiency virus. Hum Gene ner 11, 439-447.
42. Sodroski, J., Trus, M., Perkins, D., Patarca, R., Wong-Staal, F., Gelmann, E., Gallo, R. & Haseltine, W. A. (1984). Repetitive structure in the long-terminal-repeat element of a type II human T-cell leukemia virus. Proc Natl Acad Sci U S A 81, 4617-4621.
43. Sommer, P., Vartanian, J.-P., Wachsmuth, M., Henry, M., Guetard, D. & Wain-Hobson, S. (2004). Anti-termination by SIV Tat requires flexibility of the nascent TAR structure. J Mol Biol 344, 11-28.
44. Soneoka, Y., Cannon, P. M., Ramsdale, E. E., Griffiths, J. C., Romano, G., Kingsman, S. M. & Kingsman, A. J. (1995). A transient three-plasmid expression system for the production of high titer retroviral vectors. Nucleic Acids Res 23, 628-633.
45. Strappe, P. M., Greatorex, J., Thomas, J., Biswas, P., McCann, E & Lever, A. M. L. (2003). The packaging signal of simian immunodeficiency virus is upstream of the major splice donor at a distance from the RNA cap site similar to that of human immunodeficiency virus types 1 and 2. J Gen Virol 84, 2423-2430.
46. Swain, A. & Coffin, J. M. (1989). Polyadenylation at correct sites in genome RNA is not required for retrovirus replication or genome encapsidation. J Virol 63, 3301-3306.
47. Swain, A. & Coffin, J. M. (1993). Influence of sequences in the long terminal repeat and flanking cell DNA on polyadenylation of retroviral transcripts. J Virol 67, 6265-6269.
48. Swanstrom, R., Varmus, H. E. & Bishop, J. M. (1981). The terminal redundancy of the retrovirus genome facilitates chain elongation by reverse transcriptase. J Biol Chem 256, 1115-1121.
49. Topping, R., Demoitie, M.-A., Shin, N. H. & Telesnitsky, A. (1998). Cis-acting elements required for strong stop acceptor template selection during Moloney murine leukemia virus reverse transcription. J Mol Biol 281, 1-15.
50. Verhoef, K., Marzio, G., Hillen, W., Bujard, H. & Berkhout, B. (2001). Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat. J Virol 75, 979-987.
51. Wagner, R., Graf, M., Bieler, K., Wolf, H., Grunwald, T., Foley, P. & Überla, K. (2000). Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: implications for the safety of lentiviral vectors. Hum Gene Ther 11, 2403-2413.