Vulnerable window for conduction block in a one-dimensional cable of cardiac cells, 1: Single extrasystoles

Biophysical Journal

Volumn 91, Issue 3, 2006, Pages 793-804

  Qu, Zhilin ^a   Garfinkel, Alan ^a   Weiss, James N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXTRASYSTOLE; GAP JUNCTION; HEART MUSCLE CELL; KINEMATICS; NERVE BLOCK; NERVE CONDUCTION; NONHUMAN; RABBIT; SIMULATION;

EID: 33746769811     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.106.080945     Document Type: Article

References (54)

1. Chen, P.-S., P. D. Wolf, E. G. Dixon, N. D. Danieley, D. W. Frazier, W. M. Smith, and R. E. Ideker. 1988. Mechanism of ventricular vulnerability to single premature stimuli in open chest dogs. Circ. Res. 62:1191-1209.
2. Shibata, N., P. S. Chen, E. G. Dixon, P. D. Wolf, N. D. Danieley, W. M. Smith, and R. E. Ideker. 1988. Influence of shock strength and timing on induction of ventricular arrhythmias in dogs. Am. J. Physiol. 255:H891-H901.
3. Winfree, A. T. 1989. Electrical instability in cardiac muscle: phase singularities and rotors. J. Theor. Biol. 138:353-405.
4. Roth, B. J. 1998. The pinwheel experiment revisited. J. Theor. Biol. 190:389-393.
5. Frazier, D. W., P. D. Wolf, J. M. Wharton, A. S. Tang, W. M. Smith, and R. E. Ideker. 1989. Stimulus-induced critical point. Mechanism for electrical initiation of reentry in normal canine myocardium. J. Clin. Invest. 83:1039-1052.
6. Trayanova, N., and J. Eason. 2002. Shock-induced arrhythmogenesis in the myocardium. Chaos. 12:962-972.
7. Rodriguez, B., L. Li, J. C. Eason, I. R. Efimov, and N. A. Trayanova. 2005. Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks. Circ. Res. 97:168-175.
8. El-Sherif, N., W. B. Gough, and M. Restivo. 1991. Reentrant ventricular arrhythmias in the late myocardial infarction period: Mechanism by which a short-long-short cardiac sequence facilitates the induction of reentry. Circulation. 83:268-278.
9. Starobin, J. M., Y. I. Zilberter, E. M. Rusnak, and C. F. Starmer. 1996. Wavelet formation in excitable cardiac tissue: the role of wavefront-obstacle interactions in initiating high-frequency fibrillatory-like arrhythmias. Biophys. J. 70:581-594.
10. Henry, H., and W. J. Rappel. 2004. The role of M cells and the long QT syndrome in cardiac arrhythmias: simulation studies of reentrant excitations using a detailed electrophysiological model. Chaos. 14:172-182.
11. Antzelevitch, C., S. Sicouri, S. H. Litovsky, A. Lukas, S. C. Krishnan, J. M. Di Diego, G. A. Gintant, and D. W. Liu. 1991. Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells. Circ. Res. 69:1427-1449.
12. Laurita, K. R., S. D. Girouard, and D. S. Rosenbaum. 1996. Modulation of ventricular repolarization by a premature stimulus. Role of epicardial dispersion of repolarization kinetics demonstrated by optical mapping of the intact guinea pig heart. Circ. Res. 79:493-503.
13. Akar, F. G., and D. S. Rosenbaum. 2003. Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure. Circ. Res. 93:638-645.
14. Restivo, M., W. Gough, and N. el-Sherif. 1990. Ventricular arrhythmias in the subacute myocardial infarction period. High-resolution activation and refractory patterns of reentrant rhythms. Circ. Res. 66:1310-1327.
15. Qu, Z., A. Garfinkel, P. S. Chen, and J. N. Weiss. 2000. Mechanisms of discordant alternans and induction of reentry in simulated cardiac tissue. Circulation. 102:1664-1670.
16. Comtois, P., A. Vinet, and S. Nattel. 2005. Wave block formation in homogeneous excitable media following premature excitations: dependence on restitution relations. Phys. Rev. E. 72:031919.
17. Akar, F. G., G. X. Yan, C. Antzelevitch, and D. S. Rosenbaum. 2002. Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome. Circulation. 105:1247-1253.
18. Restivo, M., E. B. Caref, D. O. Kozhevnikov, and N. El-Sherif. 2004. Spatial dispersion of repolarization is a key factor in the arrhythmogenicity of long QT syndrome. J. Cardiovasc. Electrophysiol. 15:323-331.
19. Pastore, J. M., S. D. Girouard, K. R. Laurita, F. G. Akar, and D. S. Rosenbaum. 1999. Mechanism linking T-wave alternans to the genesis of cardiac fibrillation. Circulation. 99:1385-1394.
20. Watanabe, M. A., F. H. Fenton, S. J. Evans, H. M. Hastings, and A. Karma. 2001. Mechanisms for discordant alternans. J. Cardiovasc. Electrophysiol. 12:196-206.
21. Fox, J. J., M. L. Riccio, F. Hua, E. Bodenschatz, and R. F. Gilmour. 2002. Spatiotemporal transition to conduction block in canine ventricle. Circ. Res. 90:289-296.
22. Echebarria, B., and A. Karma. 2002. Instability and spatiotemporal dynamics of alternans in paced cardiac tissue. Phys. Rev. Lett. 88:208101.
23. Sinha, S., and D. J. Christini. 2002. Termination of reentry in an inhomogeneous ring of model cardiac cells. Phys. Rev. E. 66:061903.
24. Sampson, K. J., and C. S. Henriquez. 2001. Simulation and prediction of functional block in the presence of structural and ionic heterogeneity. Am. J. Physiol. Heart Circ. Physiol. 281:H2597-H2603.
25. Sampson, K. J., and C. S. Henriquez. 2002. Interplay of ionic and structural heterogeneity on functional action potential duration gradients: Implications for arrhythmogenesis. Chaos. 12:819-828.
26. Laurita, K. R., and D. S. Rosenbaum. 2000. Interdependence of modulated dispersion and tissue structure in the mechanism of unidirectional block. Circ. Res. 87:922-928.
27. Qu, Z., A. Garfinkel, and J. N. Weiss. 2006. Vulnerable window for conduction block in a one-dimensional cable of cardiac cells, 2: Multiple extrasystoles. Biophys. J. 91:805-815.
28. Luo, C. H., and Y. Rudy. 1991. A model of the ventricular cardiac action potential: depolarization, repolarization, and their interaction. Circ. Res. 68:1501-1526.
29. Goldhaber, J. I., L. H. Xie, T. Duong, C. Motter, K. Khuu, and J. N. Weiss. 2005. Action potential duration restitution and alternans in rabbit ventricular myocytes: the key role of intracellular calcium cycling. Circ. Res. 96:459-466.
30. Courtemanche, M. 1996. Complex spiral wave dynamics in a spatially distributed ionic model of cardiac electrical activity. Chaos. 6:579-600.
31. Fox, J. J., R. F. Gilmour, and E. Bodenschatz. 2002. Conduction block in one-dimensional heart fibers. Phys. Rev. Lett. 89:198101.
32. Fox, J. J., M. L. Riccio, P. Drury, A. Werthman, and R. F. Gilmour Jr. 2003. Dynamic mechanism for conduction block in heart tissue. New Journal of Physics. 5:101.101-101.114.
33. Henry, H., and W. J. Rappel. 2005. Dynamics of conduction blocks in a model of paced cardiac tissue. Phys. Rev. E. 71:051911.
34. Starmer, C. F., V. N. Biktashev, D. N. Romashko, M. R. Stepanov, O. N. Makarova, and V. I. Krinsky. 1993. Vulnerability in an excitable medium: analytical and numerical studies of initiating unidirectional propagation. Biophys. J. 65:1775-1787.
35. Starmer, C. F., A. A. Lastra, V. V. Nesterenko, and A. O. Grant. 1991. Proarrhythmic response to sodium channel blockade: theoretical model and numerical experiments. Circulation. 84:1364-1377.
36. Quan, W., and Y. Rudy. 1990. Unidirectional block and reentry of cardiac excitation: a model study. Circ. Res. 66:367-382.
37. Restivo, M., W. B. Gough, and N. El-Sherif. 1990. Ventricular arrhythmias in the subacute myocardial infarction period: High-resolution activation and refractory patterns of reentrant rhythms. Circ. Res. 66:1310-1327.
38. Viswanathan, P. C., R. M. Shaw, and Y. Rudy. 1999. Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study. Circulation. 99:2466-2474.
39. Han, J., and G. K. Moe. 1964. Nonuniform recovery of excitability in ventricular muscle. Circ. Res. 14:44-60.
40. Laurita, K. R., S. D. Girouard, F. G. Akar, and D. S. Rosenbaum. 1998. Modulated dispersion explains changes in arrhythmia vulnerability during premature stimulation of the heart. Circulation. 98:2774-2780.
41. Gough, W., R. Mehra, M. Restivo, R. Zeiler, and N. El-Sherif. 1985. Reentrant ventricular arrhythmias in the late myocardial infarction period in the dog. 13. Correlation of activation and refractory maps. Circ. Res. 57:432-442.
42. Peters, N. S., and A. L. Wit. 1998. Myocardial architecture and ventricular arrhythmogenesis. Circulation. 97:1746-1754.
43. Akar, F. G., D. D. Spragg, R. S. Tunin, D. A. Kass, and G. F. Tomaselli. 2004. Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy. Circ. Res. 95:717-725.
44. Baker, L. C., B. London, B. R. Choi, G. Koren, and G. Salama. 2000. Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotes reentrant ventricular tachycardia. Circ. Res. 86:396-407.
45. Choi, B. R., T. Liu, and G. Salama. 2001. The distribution of refractory periods influences the dynamics of ventricular fibrillation. Circ. Res. 88:E49-E58.
46. Anyukhovsky, E. P., E. A. Sosunov, and M. R. Rosen. 1996. Regional difference in electrophysiological properties of epicardium, midmyocardium, and endocardium: in vitro and in vivo correlations. Circulation. 94:1981-1988.
47. Cao, J. M., Z. Qu, Y. H. Kim, T. J. Wu, A. Garfinkel, J. N. Weiss, H. S. Karagueuzian, and P. S. Chen. 1999. Spatiotemporal heterogeneity in the induction of ventricular fibrillation by rapid pacing: importance of cardiac restitution properties. Circ. Res. 84:1318-1331.
48. Yan, G. X., W. Shimizu, and C. Antzelevitch. 1998. Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations. Circulation. 98:1921-1927.
49. Panfilov, A. V., and A. N. Rudenko. 1987. Two regimes of the scroll ring drift in the three-dimensional active media. Physica D. 28:215-218.
50. Fenton, F., and A. Karma. 1998. Fiber-rotation-induced vortex turbulence in thick myocardium. Phys. Rev. Lett. 81:481-484.
51. Qu, Z., J. Kil, F. Xie, A. Garfinkel, and J. N. Weiss. 2000. Scroll wave dynamics in a three-dimensional cardiac tissue model: roles of restitution, thickness, and fiber rotation. Biophys. J. 78:2761-2775.
52. Harrild, D., and C. Henriquez. 2000. A computer model of normal conduction in the human atria. Circ. Res. 87:E25-E36.
53. Vigmond, E. J., R. Ruckdeschel, and N. Trayanova. 2001. Reentry in a morphologically realistic atrial model. J. Cardiovasc. Electrophysiol. 12:1046-1054.
54. Xie, F., Z. Qu, J. Yang, A. Baher, J. N. Weiss, and A. Garfinkel. 2004. A simulation study of the effects of cardiac anatomy in ventricular fibrillation. J. Clin. Invest. 113:686-693.