2 MORPHOLINO 8 PHENYLCHROMONE;
AS 605240;
CARBOXYMETHYLCELLULOSE;
COLLAGEN ANTIBODY;
PHOSPHATIDYLINOSITOL 3 KINASE;
PHOSPHATIDYLINOSITOL 3 KINASE GAMMA;
PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR;
PROTEIN INHIBITOR;
PROTEIN P110;
UNCLASSIFIED DRUG;
WORTMANNIN;
ARTICLE;
CHRONIC GRAFT VERSUS HOST DISEASE;
CLINICAL FEATURE;
DRUG EFFICACY;
DRUG STRUCTURE;
ENZYME ACTIVITY;
HISTOPATHOLOGY;
IN VIVO STUDY;
KIDNEY DISEASE;
LONG TERM CARE;
NONHUMAN;
PROTEIN TARGETING;
PROTEINURIA;
RHEUMATOID ARTHRITIS;
SURVIVAL;
SYMPTOM;
SYSTEMIC LUPUS ERYTHEMATOSUS;
TOXICITY TESTING;
Function of PI3Kγ in thymocyte development, T-cell activation, and neutrophil migration
SASAKI T, IRIE-SASAKI J, JONES RG et al.: Function of PI3Kγ in thymocyte development, T-cell activation, and neutrophil migration. Science (2000) 287:1040-1045.
Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ-deficient mice
DEL PRETE A, VERMI W, DANDER E et al.: Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ-deficient mice. EMBO (2004) 23:3505-3515.
Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation
HIRSCH E, KATANAEV VL, GARLANDA C et al.: Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation. Science (2000) 287:1049-1053.
Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
CAMPS M, RÜCKLE T, JI H et al.: Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat. Med. (2005) 11:936-943.
PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus
BARBER DF, BARTOLOMÉ A, HERNANDEZ C et al.: PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus. Nat. Med. (2005) 11:933-935.
Pathogenic T cells in murine lupus exhibit spontaneous signaling through phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways
NICULESCU F, NGUYEN P, NICULESCU T, RUS H, RUS V, VIA CS: Pathogenic T cells in murine lupus exhibit spontaneous signaling through phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. Arthritis Rheum. (2003) 48:1071-1079.
Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo
BORLADO LR, REDONO C, ALVAREZ B et al.: Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo. FASEB J. (2000) 14:895-903.
