Arginine 54 and tyrosine 118 residues of αA-crystallin are crucial for lens formation and transparency

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 7, 2006, Pages 3004-3010

  Xia, Chun Hong ^a   Liu, Haiquan ^a   Chang, Bo ^b   Cheng, Catherine ^a   Cheung, Debra ^a   Wang, Meng ^a   Huang, Qingling ^c   Horwitz, Joseph ^c   Gong, Xiaohua ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JACKSON LABORATORY   (United States)

^c JULES STEIN EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; ARGININE; BETA CRYSTALLIN; GAMMA CRYSTALLIN; GREEN FLUORESCENT PROTEIN; TYROSINE; ACTIN;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATARACT; CELL LOSS; CELL STRUCTURE; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE IDENTIFICATION; GENOME; HISTOPATHOLOGY; IN VIVO STUDY; LENS EPITHELIUM; LINKAGE ANALYSIS; MALE; MISSENSE MUTATION; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SLIT LAMP; TWO DIMENSIONAL ELECTROPHORESIS; ANIMAL; C3H MOUSE; C57BL MOUSE; CHROMOSOME MAP; DISEASE MODEL; DOMINANT GENE; EPITHELIUM CELL; GENETIC LINKAGE; GENETICS; LENS; METABOLISM; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; POINT MUTATION; RECESSIVE GENE; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ACTINS; ALPHA-CRYSTALLIN A CHAIN; ANIMALS; ARGININE; CATARACT; CHROMOSOME MAPPING; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EPITHELIAL CELLS; FEMALE; GENES, DOMINANT; GENES, RECESSIVE; GREEN FLUORESCENT PROTEINS; LENS, CRYSTALLINE; LINKAGE (GENETICS); MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MITOCHONDRIA; PHENOTYPE; POINT MUTATION; TYROSINE;

EID: 33746708291     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-0178     Document Type: Article

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