Rats subjected to extended L-tryptophan restriction during early postnatal stage exhibit anxious-depressive features and structural changes

Journal of Neuropathology and Experimental Neurology

Volumn 65, Issue 6, 2006, Pages 562-570

  Zhang, Limei ^a   Guadarrama, Leyla ^a   Corona Morales, Aleph A ^a   Vega Gonzalez, Arturo ^a   Rocha, Luisa ^b   Escobar, Alfonso ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Animal model of depression; BrdU; c Fos; Dendrite spines; Dendrite varicosities; Golgi Cox; Serotonin

Indexed keywords

BROXURIDINE; PROTEIN C FOS; SEROTONIN; TRYPTOPHAN; TRYPTOPHAN HYDROXYLASE;

AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BRAIN CORTEX; BRAIN STEM; CONTROLLED STUDY; CORPUS STRIATUM; DENTATE GYRUS; DEPRESSION; DIET RESTRICTION; DIET THERAPY; DIETARY INTAKE; EMOTIONAL DISORDER; FORCED SWIMMING TEST; GOLGI COMPLEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; MAIZE; MALE; MAZE TEST; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PERINATAL PERIOD; PREFRONTAL CORTEX; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SEROTONINERGIC SYSTEM; STATISTICAL SIGNIFICANCE; AGE; ANIMAL; ANXIETY; BRAIN; CELL COUNT; COMPARATIVE STUDY; DISEASE MODEL; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; NEWBORN; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN RESTRICTION; SILVER STAINING; SWIMMING; ULTRASTRUCTURE; WISTAR RAT;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANXIETY; BEHAVIOR, ANIMAL; BRAIN; BROMODEOXYURIDINE; CELL COUNT; DEPRESSION; DIET, PROTEIN-RESTRICTED; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; MALE; MAZE LEARNING; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; SEROTONIN; SILVER STAINING; SWIMMING; TRYPTOPHAN; TRYPTOPHAN HYDROXYLASE;

EID: 33746692033     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-200606000-00004     Document Type: Article

References (58)

1. Schatzberg AF, Garlow SJ, Nemeroff CB. Molecular and cellular mechanisms in depression. In: Davis KL, Charney D, Coyle JT, et al., eds. Neuropsychopharmacology: The Fifth Generation of Progress. Philadelphia: Lippincott Williams & Wilkins, 2002:1039-50
2. Mann JJ, Huang YY, Underwood MD, et al. A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide. Arch Gen Psychiatry 2000;57:729-38
3. Schildkraut JJ. Catecholamine hypothesis of affective disorders: A review of supporting evidence. Am J Psychiatry 1965;130:695-99
4. Carlsson A, Fuxe K, Ungerstedt U. The effect of imipramine on central 5 hydroxytryptamine neurons. J Pharm Pharmacol 1968;20:150-51
5. Vetulani J, Nalepa I. Antidepressant: Past, present and future. Eur J Pharmacol 2000;405:351-63
6. Panzer MJ. Are SSRIs really more effective for anxious depression? Ann Clin Psychiatry 2005;17:23-29
7. Whitaker-Azmitia PM. Role of serotonin and other neurotransmitter receptors in brain development: Basis for developmental pharmacology. Pharmacol Rev 1991;43:533-61
8. Lauder JM. Ontogeny of the serotoninergic system in the rat: Serotonin as a developmental signal. Ann NY Acad Sci 1990;600:297-313
9. Vaidya VA, Merek GJ, Aghajanian GK, et al. 5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and neocortex. J Neurosci 1997;17:2785-95
10. Zetterström TSC, Pei Q, Madav TR, et al. Manipulation of brain 5-HT level affect gene expression for BDNF in rat brain. Neuropharmacology 1999;38:1063-73
11. Azmitia EC, Rubinstein VJ, Strafaci JA, et al. 5-HT1A agonist and dexamethasone reversal of para-chloroamphetamine induced loss of MAP2 and synaptophysin immunoreactivity in adult rat brain. Brain Res 1995;677:181-92
12. Mazer C, Muneyyirci J, Taheny K, et al. Serotonin depletion during synaptogenesis leads to decreased synaptic density and learning deficit in the adult rat: A possible model of neurodevelopmental disorders with cognitive deficits. Brain Res 1997;760:68-73
13. Moorman JM, Jackson A, Grahame-Smith DG, Leslie RA. Induction of c-Fos in rat forebrain by pharmacological manipulation of 5-hydroxytryptamine levels. Neuroscience 1995;68:1089-96
14. Moorman JM, Leslie RA. P-chloroamphetamine induces c-Fos in rat brain: A study of serotonin2A/2C receptor function. Neuroscience 1996;72:129-39
15. Tilakaratne N, Friedman E. Genomic responses to 5-HT1A or 5-HT2A/2C receptor activation is differentially regulated in four regions of rat brain. Eur J Pharmacol 1996;307:211-17
16. Pei Q, Lewis L, Sprakes ME, et al. Serotoninergic regulation of mRNA expression of Arc, an immediate early gene selectively localized at neural dendrites. Neuropharmacology 2000;39:463-70
17. Neumeister A. Tryptophan depletion, serotonin, and depression: Where do we stand? Psychopharmacol Bull 2003;37:99-115
18. Benkelfat C, Ellenbogen MA, Dean P, et al. Mood-lowering effect of tryptophan depletion: Enhanced susceptibility in young men a genetic risk for major affective disorders. Arch Gen Psychiatry 1994;51:687-97
19. Klaassen T, Riedel WJ, van Someren A, et al. Mood effects of 24-hour tryptophan depletion in healthy first-degree relatives of patients with affective disorders. Biol Psychiatry 1999;46:489-97
20. Quintin P, Benkelfat C, Launay JM, et al. Clinical and neurochemical effect of acute tryptophan depletion in unaffected relatives of patients with bipolar affective disorder. Biol Psychiatry 2001;50:184-90
21. Neumeister A, Konstantinidis A, Stastny J, et al. Association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioural responses to tryptophan depletion in healthy women with and without family history of depression. Arch Gen Psychiatry 2002;59:613-20
22. Delgado P, Miller HL, Salomon RM, et al. Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: Implications for the role of serotonin in the mechanism of antidepressant action. Biol Psychiatry 1999;46:212-20
23. Bressani R. Chemistry, technology and nutritive value of maize tortillas. Food Rev Int 1990;6:225-64
24. Bazua CD, Guerra R, Sterner H. Extruded corn flour as an alternative to lime-treated corn flour for tortilla preparation. J Food Sci 1979;44:940-41
25. Cohen A. The mental health of indigenous peoples: an international overview. [World Health Organization web site] July 31, 1999. Available at: http://www.who.int/hhr/activities/indigenous/en/. Accessed October 20, 2005
26. Manson SM, Shore JH, Bloom JD. The depressive experience in American Indian communities: a challenge for psychiatric theory and diagnosis. In: Kleinman A, Good B, eds. Culture and Depression: Studies in the Anthropology and Cross-Cultural Psychiatry of Affect and Disorder. Berkeley, CA: University of California Press, 1985:331-68
27. Pedersen D. Mental Health Amongst the Indigenous Peoples of Latin America. Working Paper No. 19. Series on International Mental and Behavioral Health. Cambridge, MA: Center for the Study of Culture and Medicine, Program in Medical Anthropology, Harvard University, 1993
28. Aitken AR, Törk I. Early development of serotonin-containing neurons and pathways as seen in whole-mount preparations of the fetal rat brain. J Comp Neurol 1988;274:32-47
29. IIlescas R. La teoria quimica de la formacion de nixtamal. Rev Soc Mex Hist Nat 1943;4:129-36
30. Porsolt RD, Anton G, Blavet N, et al. Behavioral despair in rats: A new model sensitive to antidepressant treatments. Eur J Pharmacol 1978;47:379-91
31. Detke MJ, Rickels M, Lucki I. Active behaviours in the rat forced swimming test differentially produced by serotoninergic and noradrenergic antidepressants. Psychopharmacology 1995;121:66-72
32. Heinrichs SCSwim stressor. In: Crawley JL, Gerfen CR, McKay R, et al., eds. Current Protocols in Neuroscience. New York: John Wiley & Sons, 1997:8.4.1-14
33. Pellow S, Chopin P, File SE, et al. Validation of open-closed arm entries in an elevated plus maze as a measure of anxiety in the rat. J Neurosci Methods 1985;14:149-67
34. File SE, Gonzalez LE, Andrews N. Comparative study of pre- and postsynaptic 5-HT1A receptor modulation of anxiety in two ethological animal tests. J Neurosci 1996;16:4810-15
35. Willner P, Towell A, Sampson D, et al. Reduction of sucrose preference by chronic unpredictable mild stress and its restoration by a tricyclic antidepressant. Psychopharmacology (Berl) 1987;93:358-64
36. Peat MA, Gibb JW. High-performance liquid chromatographic determination of indolamines, dopamine, and norepinephrine in rat brain with fluorometric detection. Analytical Biochemistry 1983;128:275-80
37. Lowry OH, Rosebrough NJ, Farr AL, et al. Protein measurement with the folin phenol reagent. J Biol Chem 1951;193:265-75
38. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. New York: Academic Press, 1998
39. Speddin M, Jay T, Costa E, et al. A pathophysiological paradigm for the therapy of psychiatric disease. Nat Rev Drug Discov 2005;4:467-76
40. Seong E, Seasholtz AF, Burmeister M. Mouse models for psychiatric disorders. Trends Genet 2002;18:643-50
41. Azmitia EC, Whitaker-Azmitia PM. Cell biology and maturation of the serotonergic system. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress. New York: Raven Press, 1995:443-80
42. Fadda F, Cocco S, Stancampiano R. A physiological method to selectively decrease brain serotonin release. Brain Res Protoc 2000;5:219-22
43. Duman RS. Depression: A case of neuronal life and death? Biol Psychiatry 2004;56:140-45
44. Imai H, Steindler DA, Kitai ST. The organization of divergent axonal projections from the midbrain raphe nuclei in the rat. J Comp Neurol 1986;243:363-80
45. Törk I. Raphe nuclei and serotonin containing system. In: Paxinos G., ed. The Rat Nervous System. Sydney: Academic Press, 1985:43-78
46. Vertes RP. PHA-L analysis of projections from the supramamillary nucleus in the rat. J Comp Neurol 1992;326:595-622
47. Törk I. Anatomy of the serotonergic system. Ann N Y Acad Sci 1990;600:9-34
48. Martin GR. 5-Hydroxytryptamine receptors. In: The IUPHAR Compendium of the Receptor Characterization and Classification. London: IUPHAR Media, 1998:167-85
49. Koh T, Nakazawa M, Kani K, Maeda T. Significant non-serotonergic raphe projection to the visual cortex of the rat. An immunohistochemical study combined with retrograde tracing. J Hirnforsch 1991;32:707-14
50. Djavadian RL. Serotonin and neurogenesis in the hippocampal dentate gyrus of adult mammals. Acta Neurobiol Exp (Wars) 2004;64:189-200
51. Willner P. Validity, reliability and utility of the chronic mild stress model of depression: A 10-year review and evaluation. Psychopharmacology (Berl) 1997;134:319-29
52. Papp M, Klimek V, Willner P. Parallel changes in dopamine D2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine. Psychopharmacology (Berl) 1994;115:441-46
53. Willner P. Dopaminergic mechanisms in depression and mania. In: Watson S, ed. Psychopharmacology: The Fourth Generation of Progress, PA online edition. New York: Lippincott Williams & Wilkins, 2000
54. Wise RA. Neuroleptics and operant behavior: The anhedonia hypothesis. Behav Brain Sci 1982;5:39-87
55. Skolnick P. Dopamine and depression. In: Schmidt WJ, Reith ME, eds. Dopamine and Glutamate in Psychiatric Disorders. Totowa, NJ: Humana Press, 2005:199-214
56. Del Rio J, Frechilla D. Glutamate and depression. In: Schmidt WJ, Raith EA, eds. Dopamine and Glutamate in Psychiatric Disorders. Totowa, NJ: Humana Press, 2005:215-34
57. Duman RS, Malberg J, Thome J. Neural plasticity to stress and antidepressant treatment. Biol Psychiatry 1999;46:1181-91
58. Duman RS, Heninger GR, Nestler EJ. A molecular and cellular theory of depression. Arch Gen Psychiatry 1997;54:597-606