Genomic responses to 5-HT(1A) or 5-HT(2A/2C) receptor activation is differentially regulated in four regions of rat brain

European Journal of Pharmacology

Volumn 307, Issue 2, 1996, Pages 211-217

  Tilakaratne, Nanda ^a   Friedman, Eitan ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

5 HT(1A) receptor; 5 HT(2A C) receptor; c fios; ngf1c; tis1

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; COMPLEMENTARY DNA; KETANSERIN; MESSENGER RNA; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; RECEPTOR SUBTYPE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 1C RECEPTOR; SEROTONIN 2A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ANTAGONISM; GENE EXPRESSION; HIPPOCAMPUS; IMMEDIATE EARLY GENE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; NORTHERN BLOTTING; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; REGULATORY MECHANISM; TISSUE DISTRIBUTION;

EID: 0030603722     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00233-6     Document Type: Article

References (25)

1. Bading, H., D. Ginty, and M.E. Greenberg, (1993) Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways, Science 260, 181-186.
2. Chomczynski, P. and N. Sacchi, (1987) Single step method of RNA isolation by acid guanidium thiocyanate phenol chloroform extraction, Anal. Biochem. 162, 156-159.
3. Davis, L.G., M.D. Dibner, and J.F. Battey, (1986) Basic Methods in Molecular Biology Elsevier, N.Y., pp. 147-149.
4. Dragunow, M., R.W. Currie, R.L.M. Faull, H.A. Robertson, and K. Jansen, (1989) Immediate early genes, kindling and long-term potentiation, Neurosci. and Biobehav. Rev. 13, 301-313.
5. 1a receptor antagonists: utility as research tools and therapeutic agents. Trends Pharmacol. Sci. 14, 441-448.
6. 1A receptor antagonist, WAY-100635, Eur. J. Pharmacol. 281, 81-88.
7. Green, A.R. and L.I. Backus, (1990) Animal models of serotonin behavior. In P.M. Whitaker-Azmitia and S.J. Peroutka (Eds.), The Neuropharmacology of Serotonin, Vol. 600, Ann. N.Y. Acad. Sci., New York, pp. 237-248.
8. 1a receptor: Pharmacological, biochemical, functional and regulatory properties. In P.M. Whitaker-Azmitia and S.J. Peroutka (Eds.), The Neuropharmacology of Serotonin, Vol. 600, Ann. N.Y. Acad. Sci., New York, pp. 114-131.
9. Hoyer. D., D.E. Clarke, J.R. Fozard, P.R. Hartig, G.R. Martin, E.J. Mylecharane, P.R. Saxena and P.P.A. Humphrey. (1994) International Union for Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol. Rev. 46, 157-203.
10. Iwaki, K., V.P. Sukhatme, H.E. Shubeita, and K.R. Chien, (1990) Alpha and beta adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal myacaridal cells, J. Biol. Chem. 265, 13809-13817.
11. 2/1C receptor activiation causes a localized expression of the immediate-early gene c-fos in rat brain: evidence for involvement of dorsal raphe nucleus projection fibers, Neurosci. 53:(2), 458-463.
12. Lim, R., B. Varnum, and H. Herschman, (1987) Cloning of tetradecanoyl phorbol ester-induced primary response' sequences and the expression in density-arrested Swiss 3T3 cells and a non-proliferative variant, Oncogene 1, 263-270.
13. 1A-receptors, as measured by behavioral tests and receptor binding in rats, Neuropharmacol. 31, 25-32.
14. Massieu, L., R. Rocamona, J.M. Palacio, and W.G.M.B. Hendrikus, (1992) Administration of quinilonic acid in the rat hippocampus induces expression of c-fos mRNA, Mol.Brain Res. 16, 88-96.
15. 1A receptors in the cerebellum of normal and x-irradiated rats during postnatal development, Neurosci. 51 (2), 475-485.
16. 1A receptors in the rat immature cerebellum, NeuroReport 4, 763-766.
17. 1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro, J. Neurochem. 66:(1),203-209.
18. 1A receptor mRNA in rat forebrain and cerebullum, Develop. Brain Res. 80, 149-157.
19. Morgan, J.I. and T. Curran, (1991) Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes, fos and jun, Ann. Rev. Neurosci. 14, 421-451.
20. Palacios, J.M., C. Waeber, D. Hoyer, and G. Mengod, (1990) Distribution of Serotonin receptors, Annals N.Y. Acad. Sci. 600, 36-50.
21. Richard, D., S. Rivest, and C. Rivier, (1992) The 5 hydroxytryptamine agonist fenfluramine increases fos like immunoreactivity in the brain, Brain Res. 594, 131-137.
22. 1a receptor antagonist WAY 100135: an in vivo microdialysis study, Eur. J. Pharmacol. 239, 195-202.
23. Sagar. S.M., F.R. Sharp, and T. Curran, (1988) Expression of c-fos protein in brain: metabolic mapping at the cellular level, Science 240, 1328-1331.
24. Sheng, M. and M.E. Greenberg, (1990) The regulation and function of c-fos and other immediate early genes in the nervous system, Neuron 4, 478-485.
25. Starkey, S.J. and M. Skingle, (1993) Effects of WAY 100135, 8-OH-DPAT, and sumatriptan on 5-HT release evoked by a single electrical pulse in slices of guinea pig dorsal raphe nucleus, Br. J. Pharmacol. 108, 100P.