A directly labeled TR-FRET assay for monitoring phosphoinositide-3-kinase activity

Combinatorial Chemistry and High Throughput Screening

Volumn 9, Issue 7, 2006, Pages 565-670

  Yang, Xiaoke ^a   Li, Puyao ^a   Feldberg, Larry ^b   Kim, Steven C ^b   Bowman, Michael ^a   Hollander, Irwin ^b   Mallon, Robert ^b   Wolf, Stanley F ^a  

^a PFIZER INC   (United States)

^b WYETH RESEARCH   (United States)

Author keywords

Grp1; PH domain; Phosphoinositide 3; PI3 Kinase; TR FRET

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 3 KINASE; REAGENT; TERBIUM;

ARTICLE; BINDING AFFINITY; CELL GROWTH; CELL MOTILITY; CELL STRUCTURE; CELL SURVIVAL; DISSOCIATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME INHIBITION; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; MONITORING; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BIOLOGICAL ASSAY; CHELATING AGENTS; COMBINATORIAL CHEMISTRY TECHNIQUES; FLUORESCENCE RESONANCE ENERGY TRANSFER; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TERBIUM;

EID: 33746648697     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/138620706777935360     Document Type: Article

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