Identification of regions of leukotriene C4 synthase which direct the enzyme to its nuclear envelope localization

Journal of Cellular Biochemistry

Volumn 98, Issue 6, 2006, Pages 1517-1527

  Svartz, Jesper ^a   Hallin, Elisabeth ^a   Shi, Yixuan ^a   Söderström, Mats ^a   Hammarström, Sven ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Bioluminescence resonance energy transfer (BRET); Eicosanoids; Fusion protein; Green fluorescent protein; Nuclear envelope; Subcellular localization; Transmembrane

Indexed keywords

AMINO ACID; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; GLUTATHIONE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; ICOSANOID; LEUKOTRIENE; LEUKOTRIENE A4; LEUKOTRIENE C4; LEUKOTRIENE C4 SYNTHASE; MEMBRANE PROTEIN; PROTEIN SUBUNIT;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL ACTIVATION; CELL NUCLEUS MEMBRANE; CELL STRAIN COS7; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME LOCALIZATION; ENZYME STRUCTURE; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; INFLAMMATORY CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OLIGOMERIZATION; OXYGENATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SEQUENCE ANALYSIS; STRUCTURAL PROTEOMICS;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; HYDROPHOBICITY; MOLECULAR SEQUENCE DATA; NUCLEAR ENVELOPE; NUCLEAR LOCALIZATION SIGNALS; PROTEIN STRUCTURE, TERTIARY;

EID: 33746551586     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20880     Document Type: Article

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