-
1
-
-
0031783251
-
Acute hepatic allograft rejection: Incidence, risk factors, and impact on outcome
-
Wiesner RH, Demetris AJ, Belle SH, et al. Acute hepatic allograft rejection: incidence, risk factors, and impact on outcome. Hepatology 1998;28:638-645
-
(1998)
Hepatology
, vol.28
, pp. 638-645
-
-
Wiesner, R.H.1
Demetris, A.J.2
Belle, S.H.3
-
2
-
-
0042360213
-
Chronic renal failure after transplantation of a nonrenal organ
-
Ojo AO, Held PJ, Port FK, et al. Chronic renal failure after transplantation of a nonrenal organ. N Engl J Med 2003;349:931-940
-
(2003)
N Engl J Med
, vol.349
, pp. 931-940
-
-
Ojo, A.O.1
Held, P.J.2
Port, F.K.3
-
3
-
-
0016724057
-
Rapamycin (AY-22,989), a new antifungal antibiotic. I: Taxonomy of the producing streptomycete and isolation of the active principle
-
Vezina C, Kudelski A, Sehgal SN. Rapamycin (AY-22,989), a new antifungal antibiotic. I: taxonomy of the producing streptomycete and isolation of the active principle. J Antibiot (Tokyo) 1975;28:721-726
-
(1975)
J Antibiot (Tokyo)
, vol.28
, pp. 721-726
-
-
Vezina, C.1
Kudelski, A.2
Sehgal, S.N.3
-
4
-
-
0030064388
-
The side effect profile of sirolimus: A phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients
-
Murgia MG, Jordan S, Kahan BD. The side effect profile of sirolimus: a phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients. Kidney Int 1996;49:209-216
-
(1996)
Kidney Int
, vol.49
, pp. 209-216
-
-
Murgia, M.G.1
Jordan, S.2
Kahan, B.D.3
-
5
-
-
0035018702
-
Dyslipidemia during sirolimus therapy in liver transplant recipients occurs with concomitant cyclosporine but not tacrolimus
-
Trotter JF, Wachs ME, Trouillot TE, et al. Dyslipidemia during sirolimus therapy in liver transplant recipients occurs with concomitant cyclosporine but not tacrolimus. Liver Transpl 2001;7:401-408
-
(2001)
Liver Transpl
, vol.7
, pp. 401-408
-
-
Trotter, J.F.1
Wachs, M.E.2
Trouillot, T.E.3
-
6
-
-
0037961738
-
Cardiovascular risk factors of sirolimus compared with cyclosporine: Early experience from two randomized trials in renal transplantation
-
Legendre C, Campistol JM, Squifflet JP, et al. Cardiovascular risk factors of sirolimus compared with cyclosporine: early experience from two randomized trials in renal transplantation. Transplant Proc 2003;35:151S-153S
-
(2003)
Transplant Proc
, vol.35
-
-
Legendre, C.1
Campistol, J.M.2
Squifflet, J.P.3
-
7
-
-
0042768010
-
Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: Incidence, risk factors, progression, and prognosis
-
Chueh SC, Kahan BD. Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: incidence, risk factors, progression, and prognosis. Transplantation 2003;76:375-382
-
(2003)
Transplantation
, vol.76
, pp. 375-382
-
-
Chueh, S.C.1
Kahan, B.D.2
-
8
-
-
0035077151
-
Steroid-free immunosuppression through thymoglobulin induction in liver transplantation
-
Eason JD, Blazek J, Mason A, et al. Steroid-free immunosuppression through thymoglobulin induction in liver transplantation. Transplant Proc 2001;33:1470-1471
-
(2001)
Transplant Proc
, vol.33
, pp. 1470-1471
-
-
Eason, J.D.1
Blazek, J.2
Mason, A.3
-
9
-
-
0037469018
-
Steroid-free liver transplantation using rabbit antithymocyte globulin and early tacrolimus monotherapy
-
Eason JD, Nair S, Cohen AJ, et al. Steroid-free liver transplantation using rabbit antithymocyte globulin and early tacrolimus monotherapy. Transplantation 2003;75:1396-1399
-
(2003)
Transplantation
, vol.75
, pp. 1396-1399
-
-
Eason, J.D.1
Nair, S.2
Cohen, A.J.3
-
10
-
-
0036193103
-
Immunoprophylaxis with basiliximab, a chimeric anti-interleukin-2 receptor monoclonal antibody, in combination with azathioprine-containing triple therapy in liver transplant recipients
-
Calmus Y, Scheele JR, Gonzalez-Pinto I, et al. Immunoprophylaxis with basiliximab, a chimeric anti-interleukin-2 receptor monoclonal antibody, in combination with azathioprine-containing triple therapy in liver transplant recipients. Liver Transpl 2002;8:123-131
-
(2002)
Liver Transpl
, vol.8
, pp. 123-131
-
-
Calmus, Y.1
Scheele, J.R.2
Gonzalez-Pinto, I.3
-
11
-
-
0036192366
-
Improved treatment response with basiliximab immunoprophylaxis after liver transplantation: Results from a double-blind randomized placebo-controlled trial
-
Neuhaus P, Clavien PA, Kittur D, et al. Improved treatment response with basiliximab immunoprophylaxis after liver transplantation: results from a double-blind randomized placebo-controlled trial. Liver Transpl 2002;8:132-142
-
(2002)
Liver Transpl
, vol.8
, pp. 132-142
-
-
Neuhaus, P.1
Clavien, P.A.2
Kittur, D.3
-
12
-
-
17744397506
-
Use of daclizumab as initial immunosuppression in liver transplant recipients with impaired renal function
-
Emre S, Gondolesi G, Polat K, et al. Use of daclizumab as initial immunosuppression in liver transplant recipients with impaired renal function. Liver Transpl 2001;7:220-225
-
(2001)
Liver Transpl
, vol.7
, pp. 220-225
-
-
Emre, S.1
Gondolesi, G.2
Polat, K.3
-
13
-
-
0035872742
-
Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation
-
Vincenti F, Ramos E, Brattstrom C, et al. Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation. Transplantation 2001;71:1282-1287
-
(2001)
Transplantation
, vol.71
, pp. 1282-1287
-
-
Vincenti, F.1
Ramos, E.2
Brattstrom, C.3
-
14
-
-
0034719368
-
Experience with daclizumab in liver transplantation: Renal transplant dosing without calcineurin inhibitors is insufficient to prevent acute rejection in liver transplantation
-
Hirose R, Roberts JP, Quan D, et al. Experience with daclizumab in liver transplantation: renal transplant dosing without calcineurin inhibitors is insufficient to prevent acute rejection in liver transplantation. Transplantation 2000;69:307-311
-
(2000)
Transplantation
, vol.69
, pp. 307-311
-
-
Hirose, R.1
Roberts, J.P.2
Quan, D.3
-
15
-
-
10844292763
-
Immunosuppressive drugs for kidney transplantation
-
Halloran PF. Immunosuppressive drugs for kidney transplantation. N Engl J Med 2004;351:2715-2729
-
(2004)
N Engl J Med
, vol.351
, pp. 2715-2729
-
-
Halloran, P.F.1
-
16
-
-
0036871663
-
What's in the pipeline? New immunosuppressive drugs in transplantation
-
Vincenti F. What's in the pipeline? New immunosuppressive drugs in transplantation. Am J Transplant 2002;2:898-903
-
(2002)
Am J Transplant
, vol.2
, pp. 898-903
-
-
Vincenti, F.1
-
17
-
-
3042743990
-
FTY720: Sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function
-
Brinkmann V, Cyster JG, Hla T. FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. Am J Transplant 2004;4:1019-1025
-
(2004)
Am J Transplant
, vol.4
, pp. 1019-1025
-
-
Brinkmann, V.1
Cyster, J.G.2
Hla, T.3
-
18
-
-
11144343254
-
Janus kinase 3: A novel target for selective transplant immunosuppression
-
Podder H, Kahan BD. Janus kinase 3: a novel target for selective transplant immunosuppression. Expert Opin Ther Targets 2004;8:613-629
-
(2004)
Expert Opin Ther Targets
, vol.8
, pp. 613-629
-
-
Podder, H.1
Kahan, B.D.2
-
19
-
-
0242332186
-
Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor
-
Changelian PS, Flanagan ME, Ball DJ, et al. Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. Science 2003;302:875-878
-
(2003)
Science
, vol.302
, pp. 875-878
-
-
Changelian, P.S.1
Flanagan, M.E.2
Ball, D.J.3
-
20
-
-
20244368823
-
Immunosuppression by the JAK3 inhibitor CP-690,550 delays rejection and significantly prolongs kidney allograft survival in non-human primates
-
Borie DC, Changelian PS, Larson MJ, et al. Immunosuppression by the JAK3 inhibitor CP-690,550 delays rejection and significantly prolongs kidney allograft survival in non-human primates. Transplantation 2005;79:791-801
-
(2005)
Transplantation
, vol.79
, pp. 791-801
-
-
Borie, D.C.1
Changelian, P.S.2
Larson, M.J.3
-
21
-
-
0038037898
-
Effects of the malononitrilamide FK778 on immune functions in vitro in whole blood from non-human primates and healthy human volunteers
-
Birsan T, Dambrin C, Klupp J, et al. Effects of the malononitrilamide FK778 on immune functions in vitro in whole blood from non-human primates and healthy human volunteers. Transpl Immunol 2003;11:163-167
-
(2003)
Transpl Immunol
, vol.11
, pp. 163-167
-
-
Birsan, T.1
Dambrin, C.2
Klupp, J.3
-
22
-
-
0037708567
-
Synergistic effects of malononitrilamides (FK778, FK779) with tacrolimus (FK506) in prevention of acute heart and kidney allograft rejection and reversal of ongoing heart allograft rejection in the rat
-
Bilolo KK, Ouyang J, Wang X, et al. Synergistic effects of malononitrilamides (FK778, FK779) with tacrolimus (FK506) in prevention of acute heart and kidney allograft rejection and reversal of ongoing heart allograft rejection in the rat. Transplantation 2003;75:1881-1887
-
(2003)
Transplantation
, vol.75
, pp. 1881-1887
-
-
Bilolo, K.K.1
Ouyang, J.2
Wang, X.3
-
23
-
-
16244382061
-
FK778 controls acute rejection after rat liver allotransplantation showing positive interaction with FK506
-
Yamamoto S, Okuda T, Yamasaki K, et al. FK778 controls acute rejection after rat liver allotransplantation showing positive interaction with FK506. Transplant Proc 2005;37:126-129
-
(2005)
Transplant Proc
, vol.37
, pp. 126-129
-
-
Yamamoto, S.1
Okuda, T.2
Yamasaki, K.3
-
24
-
-
29644438538
-
An overview of the pharmacokinetics and pharmacodynamics of efalizumab: A monoclonal antibody approved for use in psoriasis
-
Joshi A, Bauer R, Kuebler P, et al. An overview of the pharmacokinetics and pharmacodynamics of efalizumab: a monoclonal antibody approved for use in psoriasis. J Clin Pharmacol 2006;46:10-20
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 10-20
-
-
Joshi, A.1
Bauer, R.2
Kuebler, P.3
-
25
-
-
33644872811
-
LFA-1 (CD11a) as a therapeutic target
-
Nicolls MR, Gill RG. LFA-1 (CD11a) as a therapeutic target. Am J Transplant 2006;6:27-36
-
(2006)
Am J Transplant
, vol.6
, pp. 27-36
-
-
Nicolls, M.R.1
Gill, R.G.2
-
26
-
-
0036023131
-
CTLA4Ig combined with anti-LFA-1 prolongs cardiac allograft survival indefinitely
-
Corbascio M, Ekstrand H, Osterholm C, et al. CTLA4Ig combined with anti-LFA-1 prolongs cardiac allograft survival indefinitely. Transpl Immunol 2002;10:55-61
-
(2002)
Transpl Immunol
, vol.10
, pp. 55-61
-
-
Corbascio, M.1
Ekstrand, H.2
Osterholm, C.3
-
27
-
-
10744228165
-
Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance
-
Zheng XX, Sanchez-Fueyo A, Sho M, et al. Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance. Immunity 2003;19:503-514
-
(2003)
Immunity
, vol.19
, pp. 503-514
-
-
Zheng, X.X.1
Sanchez-Fueyo, A.2
Sho, M.3
-
28
-
-
0038805159
-
Campath-1H induction plus rapamycin monotherapy for renal transplantation: Results of a pilot study
-
Knechtle SJ, Pirsch JD, Fechner JJ, et al. Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot study. Am J Transplant 2003;3:722-730
-
(2003)
Am J Transplant
, vol.3
, pp. 722-730
-
-
Knechtle, S.J.1
Pirsch, J.D.2
Fechner, J.J.3
-
29
-
-
0038638396
-
Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H)
-
Kirk AD, Hale DA, Mannon RB, et al. Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H). Transplantation 2003;76:120-129
-
(2003)
Transplantation
, vol.76
, pp. 120-129
-
-
Kirk, A.D.1
Hale, D.A.2
Mannon, R.B.3
-
30
-
-
0942277001
-
The use of rituximab, anti-CD20 monoclonal antibody, in pediatric transplantation
-
Pescovitz MD. The use of rituximab, anti-CD20 monoclonal antibody, in pediatric transplantation. Pediatr Transplant 2004;8:9-21
-
(2004)
Pediatr Transplant
, vol.8
, pp. 9-21
-
-
Pescovitz, M.D.1
-
31
-
-
20044386299
-
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties
-
Larsen CP, Pearson TC, Adams AB, et al. Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. Am J Transplant 2005;5:443-453
-
(2005)
Am J Transplant
, vol.5
, pp. 443-453
-
-
Larsen, C.P.1
Pearson, T.C.2
Adams, A.B.3
-
32
-
-
0014941813
-
A theory of self-nonself discrimination
-
Bretscher P, Cohn M. A theory of self-nonself discrimination. Science 1970;169:1042-1049
-
(1970)
Science
, vol.169
, pp. 1042-1049
-
-
Bretscher, P.1
Cohn, M.2
-
33
-
-
0027403299
-
The role of the CD28 receptor during T cell responses to antigen
-
Linsley PS, Ledbetter JA. The role of the CD28 receptor during T cell responses to antigen. Annu Rev Immunol 1993;11:191-212
-
(1993)
Annu Rev Immunol
, vol.11
, pp. 191-212
-
-
Linsley, P.S.1
Ledbetter, J.A.2
-
34
-
-
0032543306
-
The role of T-cell costimulatory activation pathways in transplant rejection
-
Sayegh MH, Turka LA. The role of T-cell costimulatory activation pathways in transplant rejection. N Engl J Med 1998;338:1813-1821
-
(1998)
N Engl J Med
, vol.338
, pp. 1813-1821
-
-
Sayegh, M.H.1
Turka, L.A.2
-
35
-
-
0026459468
-
T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo
-
Turka LA, Linsley PS, Lin H, et al. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc Natl Acad Sci USA 1992;89:11102-11105
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11102-11105
-
-
Turka, L.A.1
Linsley, P.S.2
Lin, H.3
-
36
-
-
15844404353
-
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
-
Larsen CP, Elwood ET, Alexander DZ, et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 1996;381:434-438
-
(1996)
Nature
, vol.381
, pp. 434-438
-
-
Larsen, C.P.1
Elwood, E.T.2
Alexander, D.Z.3
-
37
-
-
12644262358
-
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
-
Kirk AD, Harlan DM, Armstrong NN, et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci USA 1997;94:8789-8794
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8789-8794
-
-
Kirk, A.D.1
Harlan, D.M.2
Armstrong, N.N.3
-
38
-
-
23944502334
-
Costimulation blockade with belatacept in renal transplantation
-
Vincenti F, Larsen C, Durrbach A, et al. Costimulation blockade with belatacept in renal transplantation. N Engl J Med 2005;353:770-781
-
(2005)
N Engl J Med
, vol.353
, pp. 770-781
-
-
Vincenti, F.1
Larsen, C.2
Durrbach, A.3
-
39
-
-
19944412462
-
Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival
-
Adams AB, Shirasugi N, Jones TR, et al. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. J Immunol 2005;174:542-550
-
(2005)
J Immunol
, vol.174
, pp. 542-550
-
-
Adams, A.B.1
Shirasugi, N.2
Jones, T.R.3
|