Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure

Kidney International

Volumn 70, Issue 3, 2006, Pages 496-506

  Holly, M K ^a   Dear, J W ^a   Hu, X ^a   Schechter, A N ^a   Gladwin, M T ^b   Hewitt, S M ^c   Yuen, P S T ^a   Star, R A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Acute renal failure; DIGE; Proteomics; Rat model; Sepsis

Indexed keywords

ACTINONIN; ALBUMIN; BIOLOGICAL MARKER; INTERLEUKIN 10; INTERLEUKIN 6; MEPRIN; MEPRIN 1 ALPHA; MEPRIN 1 ALPHA INHIBITOR; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; AGED; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CECUM LIGATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOKINE PRODUCTION; DIFFERENCE IN GEL ELECTROPHORESIS; DISEASE MARKER; DRUG TARGETING; GEL ELECTROPHORESIS; LIGATION; MALE; MORTALITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN URINE LEVEL; RAT; SEPSIS; URINE VOLUME;

ACUTE KIDNEY INJURY; ANIMALS; ANTI-BACTERIAL AGENTS; BIOLOGICAL MARKERS; CECUM; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG DESIGN; ELECTROPHORESIS; HYDROXAMIC ACIDS; KIDNEY; KIDNEY FAILURE, ACUTE; LIGATION; LIVER; MALE; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; NITRITES; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS;

EID: 33746537718     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5001575     Document Type: Article

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