Region-specific interrelations between apoptotic proteins expression and DNA fragmentation in the neonatal rat brain

Neurochemical Research

Volumn 31, Issue 7, 2006, Pages 869-875

  Menshanov, Petr N ^a   Bannova, Anita V ^a   Dygalo, Nikolay N ^a  

^a INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

Author keywords

Apoptotic proteins; DNA fragmentation; Naturally occurring cell death; Neonatal brain

Indexed keywords

BIOLOGICAL MARKER; BRAIN PROTEIN; CASPASE 3; DNA FRAGMENT; MESSENGER RNA; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL XL; PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN REGION; BRAIN STEM; CELL DEATH; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVATION; HIPPOCAMPUS; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BLOTTING, WESTERN; BRAIN; CASPASE 3; CASPASES; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

ANIMALIA;

EID: 33746526021     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-006-9089-8     Document Type: Article

References (37)

1. Oppenheim RW (1991) Cell death during development of the nervous system. Annu Rev Neurosci 14:453-501
2. Yuan J, Yankner BA (2000) Apoptosis in the nervous system. Nature 407:802-809
3. Roth KA, D'Sa C (2001) Apoptosis and brain development. Ment Retard Dev Disabil Res Rev 7:261-266
4. Troy CM, Salvesen GS (2002) Caspases on the brain. J Neurosci Res 69:145-150
5. Young C, Klocke BJ, Tenkova T et al (2003) Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain. Cell Death Differ 10:1148-1155
6. Grojean S, Schroeder H, Pourie G et al (2003) Histopathological alterations and functional brain deficits after transient hypoxia in the newborn rat pup: a long term follow-up. Neurobiol Dis 14:265-278
7. Nakajima W, Ishida A, Lange MS et al (2000) Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat. J Neurosci 20:7994-8004
8. Chong MJ, Murray MR, Gosink EC et al (2000) Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system. Proc Natl Acad Sci USA 97:889-894
9. Parsadanian AS, Cheng Y, Keller-Peck CR et al (1998) Bcl-xL is an antiapoptotic regulator for postnatal CNS neurons. J Neurosci 18:1009-1019
10. Qiu J, Grafe MR, Schmura SM et al (2001) Differential NF-kappa B regulation of Bcl-x gene expression in hippocampus and basal forebrain in response to hypoxia. J Neurosci Res 64:223-234
11. Armstrong RC, Aja TJ, Hoang KD et al (1997) Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. J Neurosci 17:553-562
12. Lossi L, Tamagno I, Merighi A (2004) Molecular morphology of neuronal apoptosis: analysis of caspase 3 activation during postnatal development of mouse cerebellar cortex. J Mol Histol 35:621-629
13. Machaalani R, Waters KA (2003) Increased neuronal cell death after intermittent hypercapnic hypoxia in the developing piglet brainstem. Brain Res 985:127-134
14. Oomman S, Finckbone V, Dertien J et al (2004) Active caspase-3 expression during postnatal development of rat cerebellum is not systematically or consistently associated with apoptosis. J Comp Neurol 476:154-173
15. Oppenheim RW, Flavell RA, Vinsant S et al (2001) Programmed cell death of developing mammalian neurons after genetic deletion of caspases. J Neurosci 21:4752-4760
16. Kalinina TS, Bannova AV, Dygalo NN (2002) Quantitative evaluation of DNA fragmentation. Bull Exp Biol Med 134:554-556
17. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
18. Shishkina GT, Kalinina TS, Dygalo NN (2004) Attenuation of alpha(2A)-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood. Neuroscience 129:521-528
19. Suzuki Y, Farbman AI (2000) Tumor necrosis factor-alpha-induced apoptosis in olfactory epithelium in vitro: possible roles of caspase 1 (ICE), caspase 2 (ICH-1), and caspase 3 (CPP32). Exp Neurol 165:35-45
20. Tamatani M, Che YH, Matsuzaki H et al (1999) Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons. J Biol Chem 274:8531-8538
21. Shindler KS, Latham CB, Roth KA (1997) Bax deficiency prevents the increased cell death of immature neurons in Bcl-x-deficient mice. J Neurosci 17:3112-3119
22. Nudel U, Zakut R, Shani M et al (1983) The nucleotide sequence of the rat cytoplasmic beta-actin gene. Nucleic Acids Res 11:1759-1771
23. Lowry OH, Rosebrough NJ, Farr AL et al (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
24. Eldadah BA, Yakovlev AG, Faden AI (1996) A new approach for the electrophoretic detection of apoptosis. Nucleic Acids Res 24:4092-4093
25. Najbauer J, Yan XX, Leon M (2002) Internucleosomal DNA fragmentation during deprived and non-deprived olfactory development. Brain Res 926:118-125
26. White LD, Barone S Jr (2001) Qualitative and quantitative estimates of apoptosis from birth to senescence in the rat brain. Cell Death Differ 8:345-356
27. Dygalo NN, Bannova AV, Kalinina TS et al (2004) Clonidine increases caspase-3 mRNA level and DNA fragmentation in the developing rat brainstem. Brain Res Dev Brain Res 152:225-231
28. Thomaidou D, Mione MC, Cavanagh JF et al (1997) Apoptosis and its relation to the cell cycle in the developing cerebral cortex. J Neurosci 17:1075-1085
29. Yu WH (1976) The effect of 5-bromodeoxyuridine on the postnatal development of the rat cerebellum: a biochemical study. Brain Res 118:281-291
30. de Bilbao F, Guarin E, Nef P et al (1999) Postnatal distribution of cpp32/caspase 3 mRNA in the mouse central nervous system: an in situ hybridization study. J Comp Neurol 409:339-357
31. Mooney SM, Miller MW (2000) Expression of Bcl-2, bax, and caspase-3 in the brain of the developing rat. Brain Res Dev Brain Res 123:103-117
32. Vekrellis K, McCarthy MJ, Watson A et al (1997) Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development 124:1239-1249
33. Kuida K, Zheng TS, Na S et al (1996) Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384:368-372
34. Houde C, Banks KG, Coulombe N et al (2004) Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase-3-null mice. J Neurosci 24:9977-9984
35. Allsopp TE, McLuckie J, Kerr LE et al (2000) Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis. Cell Death Differ 7:984-993
36. Lorenzo HK, Susin SA (2004) Mitochondrial effectors in caspase-independent cell death. FEBS Lett 557:14-20
37. Ravagnan L, Roumier T, Kroemer G (2002) Mitochondria, the killer organelles and their weapons. J Cell Physiol 192:131-137