Increased neuronal cell death after intermittent hypercapnic hypoxia in the developing piglet brainstem

Brain Research

Volumn 985, Issue 2, 2003, Pages 127-134

  Machaalani, Rita ^a   Waters, Karen A ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

Author keywords

Apoptosis; Brain; Caspase 3; Medulla; SIDS; Swine; TUNEL

Indexed keywords

CASPASE 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; AROUSAL; ARTICLE; BRAIN STEM; CELL NUCLEUS; CELL POPULATION; CONTROLLED STUDY; CUNEATE NUCLEUS; ENZYME ACTIVITY; EVALUATION; EXPOSURE; FEMALE; GRACILE NUCLEUS; HEART FUNCTION; HYPERCAPNIA; HYPOXIA; IMMUNOHISTOCHEMISTRY; INFERIOR OLIVE; LATERAL RETICULAR NUCLEUS; MALE; MEDULLA OBLONGATA; MOTONEURON NUCLEUS; NERVE CELL NECROSIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY FUNCTION; SLEEP; SOLITARY TRACT NUCLEUS; SWINE; VAGUS NERVE;

EID: 0041878627     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(03)03003-8     Document Type: Article

References (29)

1. Blomgren K., Zhu C., Wang X., Karlsson J.O., Leverin A.L., Bahr B.A., Mallard C., Hagberg H. Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of 'pathological apoptosis'? J. Biol. Chem. 276:2001;10191-10198.
2. David J.C., Grongnet J.F. Effect of hypoxia on DNA fragmentation in different brain regions of the newborn piglet. Mol. Reprod. Dev. 57:2000;153-158.
3. Delivoria Papadopoulos M., Mishra O.P. Mechanisms of cerebral injury in perinatal asphyxia and strategies for prevention. J. Pediatr. 132:1998;S30-34.
4. D'Mello S.R., Kuan C.Y., Flavell R.A., Rakic P. Caspase-3 is required for apoptosis-associated DNA fragmentation but not for cell death in neurons deprived of potassium. J. Neurosci. Res. 59:2000;24-31.
5. Dobbing J., Sands J. Comparative aspects of the brain growth spurt. Early Hum. Dev. 3:1979;79-83.
6. Faleiro L., Kobayashi R., Fearnhead H., Lazebnik Y. Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells. EMBO J. 16:1997;2271-2281.
7. Gootman P.M., Buckley B.J., DiRusso S.M., Gootman N., Yao A.C., Pierce P.E., Griswold P.G., Epstein M.D., Cohen H.L., Nudel D.B. Age-related responses to stimulation of cardiopulmonary receptors in swine. Am. J. Physiol. 251:1986;H748-755.
8. Hall S.M., Haworth S.G. Normal adaptation of pulmonary arterial intima to extrauterine life in the pig: ultrastructural studies. J. Pathol. 149:1986;55-66.
9. Hartmann A., Hunot S., Michel P.P., Muriel M.P., Vyas S., Faucheux B.A., Mouatt Prigent A., Turmel H., Srinivasan A., Ruberg M., Evan G.I., Agid Y., Hirsch E.C. Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc. Natl. Acad. Sci. USA. 97:2000;2875-2880.
10. Hayashi T., Sakurai M., Abe K., Sadahiro M., Tabayashi K., Itoyama Y. Apoptosis of motor neurons with induction of caspases in the spinal cord after ischemia. Stroke. 29:1998;1007-1013.
11. Hunt C.E. The cardiorespiratory control hypothesis for sudden infant death syndrome. Clin. Perinatol. 19:1992;757-771.
12. Ishimaru M.J., Ikonomidou C., Tenkova T.I., Der T.C., Dikranian K., Sesma M.A., Olney J.W. Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain. J. Comp. Neurol. 408:1999;461-476.
13. Kemp J.S., Kowalski R.M., Burch P.M., Graham M.A., Thach B.T. Unintentional suffocation by rebreathing: A death scene and physiologic investigation of a possible cause of sudden infant death. J. Pediatr. 122:1993;874-880.
14. Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 26:1972;239-257.
15. Krajewska M., Wang H.G., Krajewski S., Zapata J.M., Shabaik A., Gascoyne R., Reed J.C. Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease. Cancer Res. 57:1997;1605-1613.
16. Labat-Moleur F., Guillermet C., Lorimier P., Robert C., Lantuejoul S., Brambilla E., Negoescu A. TUNEL apoptotic cell detection in tissue sections: critical evaluation and improvement critical evaluation and improvement. J. Histochem. Cytochem. 46:1998;327-334.
17. Lincz L.F. Deciphering the apoptotic pathway: all roads lead to death. Immunol. Cell. Biol. 76:1998;1-19.
18. Machaalani R., Waters K.A. The distribution and quantification of NMDA R1 mRNA and protein in the piglet brainstem and effects of intermittent hypercapnic hypoxia (IHH). Brain Res. 951:2002;293-300.
19. Machaalani R., Waters K.A. Correlations between brainstem NMDA receptor changes and active neuronal cell death after intermittent hypercapnic hypoxia in the developing piglet. Brain Res. 925:2003;127-134.
20. Martin L.J., Al-Abdulla N.A., Brambrink A.M., Kirsch J.R., Sieber F.E., Portera-Cailliau C. Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis. Brain Res. Bull. 46:1998;281-309.
21. Mooney S.M., Miller M.W. Effects of prenatal exposure to ethanol on the expression of bcl-2, bax and caspase 3 in the developing rat cerebral cortex and thalamus. Brain Res. 911:2001;71-81.
22. Olney J.W., Tenkova T., Dikranian K., Muglia L.J., Jermakowicz W.J., D'Sa C., Roth K.A. Ethanol-induced caspase-3 activation in the in vivo developing mouse brain. Neurobiol. Dis. 9:2002;205-219.
23. Paxinos G., Huang X. Atlas of the Human Brainstem. 1995;Academic Press, San Diego.
24. Scott S.C., Inman J.D., Moss I.R. Ontogeny of sleep/wake and cardiorespiratory behavior in unanesthetized piglets. Respir. Physiol. 80:1990;83-101.
25. Stennicke H.R., Salvesen G.S. Properties of the caspases. Biochim. Biophys. Acta. 1387:1998;17-31.
26. Waters K.A., Meehan B., Huang J.Q., Gravel R.A., Michaud J., Cote A. Neuronal apoptosis in sudden infant death syndrome. Pediatr. Res. 45:1999;166-172.
27. Waters K.A., Tinworth K.D. Depression of ventilatory responses after daily, cyclic hypercapnic hypoxia in piglets. J. Appl. Physiol. 90:2001;1065-1073.
28. Yoshikawa T. Atlas of Domestic Animals. 1967;University of Tokyo Press, Tokyo.
29. Yue X., Mehmet H., Penrice J., Cooper C., Cady E., Wyatt J.S., Reynolds E.O., Edwards A.D., Squier M.V. Apoptosis and necrosis in the newborn piglet brain following transient cerebral hypoxia-ischaemia. Neuropathol. Appl. Neurobiol. 23:1997;16-25.