Interleukin-6 and tumor necrosis factor-α production after acute psychological stress, exercise, and infused isoproterenol: Differential effects and pathways

Psychosomatic Medicine

Volumn 62, Issue 4, 2000, Pages 591-598

  Goebel, Marion U ^a,c   Mills, Paul J ^a   Irwin, Michael R ^a,d   Ziegler, Michael G ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

^d VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Cytokine production; Exercise; Isoproterenol; Psychological stress; Sympathetic nervous system activation

Indexed keywords

CYTOKINE; INTERLEUKIN 6; ISOPRENALINE; TUMOR NECROSIS FACTOR ALPHA;

ADRENERGIC ACTIVITY; ADULT; ARTICLE; CYTOKINE PRODUCTION; DOWN REGULATION; EXERCISE; FEMALE; HUMAN; HUMAN EXPERIMENT; IMMUNE RESPONSE; LEUKOCYTOSIS; MALE; MENTAL STRESS; NORMAL HUMAN; PHYSICAL STRESS; PRIORITY JOURNAL; SPEECH;

EID: 0033862716     PISSN: 00333174     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006842-200007000-00019     Document Type: Article

References (65)

1. The pathophysiology of tumor necrosis factor
2. The pathophysiologic roles of interleukin-6 in human disease
3. New insights into the biology of the acute phase response
4. Inflammatory cytokines and cytokine antagonists in whole blood cultures of patients with systemic juvenile chronic arthritis
5. IL-6 and APPs: Anti-inflammatory and immunosuppressive mediators
6. Neuroendocrine-immune system interaction and au-toimmunity
7. Immune-neuro-endocrine interactions: Facts and hypotheses
8. Catecholamine influences and sympathetic neural modulation of immune responsiveness
9. Modulation of lipopo-lysaccharide-induced tumor necrosis factor-α production by selective α- and β-adrenergic drugs in mice
10. Exercise and circadian rhythm-induced variations in plasma cortisol differentially regulate interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-α (TNFα) production in humans: High sensitivity of TNFα and resistance of IL-6
11. Immobilization stress may increase plasma interleukin-6 via central and peripheral catecholamines
12. The reactivity of the cardiovascular system and immunomodulation by catecholamines in juvenile chronic arthritis
13. Adrenergic regulation of macrophage-derived tumor necrosis factor-α generation during a chronic polyarthritis pain model
14. Circulating concentrations of proinflammatory cytokines in mild and moderate heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
15. β-Adrenergic receptor-dependent and -independent stimulation of adenylate cyclase is impaired during severe sepsis in humans
16. The restraint stress-induced elevation in plasma interleukin-6 negatively regulates the plasma TNF-α level
17. The effects of psychological stress on plasma interleukin-6 activity in rats
18. Exposure to physical and psychological stressors elevates plasma interleukin 6: Relationship to the activation of hypothalamic-pituitary-adrenal axis
19. Stress down-regulates lipopolysaccharide-induced expression of proinflammatory cytokines in the spleen, pituitary, and brain of mice
20. Stressor-induced alteration of cytokine production in multiple sclerosis patients and controls
21. The effects of psychological stress on humans: Increased cytokines and a Th1-like response in stress-induced anxiety
22. Psychological stress, cytokine production, and severity of upper respiratory illness
23. The acute immune response to exercise: What does it mean?
24. Sympathetic and immune interactions during dynamic exercise
25. Immune responses to inflammation and trauma: A physical training model
26. Immune response to heavy exertion
27. Sport and the overtraining syndrome: Immunological aspects
28. Effect of exhaustive exercise stress on the cytokine response
29. Effect of physical exercise on in vitro production of interleukin-1, interleukin-6, tumor necrosis factor-α, interleukin-2 and interferon-γ
30. Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-α and IL-1β production
31. Increased circulating cytokine receptors and ex vivo interleukin-1 receptor antagonist and interleukin-1β production but decreased tumor necrosis factor-α production after 5-km run
32. Regulation of cytokine and chemokine production by transmitters and co-transmitters of the autonomic nervous sytem
33. The β-adrenoceptor agonist clenbuterol is a potent inhibitor of the LPS-induced production of TNF-α and IL-6 in vitro and in vivo
34. 2-adrenoreceptor activation
35. Role of epinephrine in TNF and IL-6 production from perfused isolated rat liver
36. Norepinephrine-mediated inhibition of antitumor cytotoxic T lymphocyte generation involves a β-adrenergic receptor mechanism and decreased TNF-α gene expression
37. 2-adrenoceptors
38. Role of beta-adrenoceptor on renal interleukin-6 and tumor necrosis factor in spontaneously hypertensive rats
39. Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood
40. Epinephrine inhibits endotoxin-induced IL-1β production: Roles of tumor necrosis factor-α and IL-10
41. Epinephrine inhibits tumor necrosis factor-α and potentiates interleukin 10 production during human endotoxemia
42. Menstrual cycle effects on catecholamine and cardiovascular responses to acute stress in black but not white normotensive women
43. Effect of beta blockade on plasma catecholamine levels during psychological and exercise stress
44. L-selectin expression affects T-cell circulation following isoproterenol infusion in humans
45. A more sensitive radioenzymatic assay for catecholamines
46. Impact of three different types of exercise on components of the inflammatory response
47. The cytokine response to strenuous exercise
48. Cate-cholamine-induced leukocytosis: Early observations, current findings and future directions
49. Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: A potential role for leukocyte trafficking
50. Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans
51. Similarities and differences of the immune response to exercise and trauma: The IFN-γ concept
52. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation
53. Exercise-induced increase in serum interleukin-6 in humans is related to muscle damage
54. Prolonged submaximal eccentric exercise is associated with increased levels of plasma IL-6
55. Evidence that interleukin-6 is produced in the human skeletal muscle during prolonged running
56. Lymphocyte subset redistribution in response to acute experimental stress: Effects of gender, ethnicity, hypertension, and the sympathetic nervous system
57. Effects of β-adrenergic blockade on immunologic and cardiovascular changes induced by mental stress
58. Increased training load and the β-adrenergic-receptor system on human lymphocytes
59. Cellular responses to moderate and heavy exercise
60. The effects of moderate exercise training on natural killer cells and upper respiratory tract infections
61. Chronic stress modulates the virus-specific immune response to latent herpes simplex virus type 1
62. 2-adrenoceptors in endotoxin-stimulated renal macrophages
63. Shift toward T lymphocytes with a T helper 1 cytokine-secretion profile in the joints of patients with rheumatoid arthritis
64. Cytokine expression in advanced human atherosclerotic plaques: Dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines
65. Interleukin-6 spillover in peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure