Ex vivo hypothermic recirculatory adenoviral gene transfer to the transplanted pig heart

Journal of Gene Medicine

Volumn 8, Issue 7, 2006, Pages 795-803

  Oi, Keiji ^a   Davies, William R ^a   Tazelaar, Henry D ^a   Bailey, Kent R ^a   Federspiel, Mark J ^a   Russell, Stephen J ^a   McGregor, Christopher G A ^a  

^a MAYO CLINIC   (United States)

Author keywords

Adenoviridae; Efficiency; Experimental model; Gene transfer techniques; Heart transplantation; Perfusion; Swine

Indexed keywords

ADENOVIRUS VECTOR; UNIVERSITY OF WISCONSIN SOLUTION;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY BLOOD VESSEL; EX VIVO STUDY; EXPERIMENTAL ANIMAL; GENE TRANSFER; GENETIC TRANSDUCTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART PERFUSION; HEART TRANSPLANTATION; HYPOTHERMIC RECIRCULATORY GENE TRANSFER SYSTEM; NONHUMAN; PERFUSION PRESSURE; PLAQUE FORMING CELL; PRIORITY JOURNAL; SWINE; TEMPERATURE;

ADENOVIRIDAE; ANIMALS; COLD; EDEMA; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEART TRANSPLANTATION; PERFUSION; SUS SCROFA; TRANSDUCTION, GENETIC; TRANSPLANTATION, HOMOLOGOUS;

ADENOVIRIDAE; ANIMALIA; SUS SCROFA;

EID: 33746217563     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.913     Document Type: Article

References (33)

1. Hosenpud JD, Bennett LE, Keck BM, Boucek MM, Novick RJ. The Registry of the International Society for Heart and Lung Transplantation: Eighteenth Official Report - 2001. J Heart Lung Transplant 2001; 20: 805-815.
2. Taylor DO, Edwards LB, Mohacsi PJ, et al. The Registry of the International Society for Heart and Lung Transplantation: Twentieth Official Adult Heart Transplant Report - 2003. J Heart Lung Transplant 2003; 22: 616-624.
3. Deng MC. Cardiac transplantation. Heart 2002; 87: 177-184.
4. Mueller XM. Drug immunosuppression therapy for adult heart transplantation. 1. Immune response to allograft and mechanism of action of immunosuppressants. Ann Thorac Surg 2004; 77: 354-362.
5. Ardehali A, Reddy R, Laks H. Gene therapy and heart transplantation. Expert Opin Investig Drugs 2000; 9: 1021-1027.
6. Vassalli G, Fleury S, Li J, et al. Gene transfer of cytoprotective and immunomodulatory molecules for prevention of cardiac allograft rejection. Eur J Cardiothorac Surg 2003; 24: 794-806.
7. Wang J, Ma Y, Knechtle SJ. Adenovirus-mediated gene transfer into rat cardiac allografts. Comparison of direct injection and perfusion. Transplantation 1996; 61: 1726-1729.
8. Lee J, Laks H, Drinkwater DC, et al. Cardiac gene transfer by intracoronary infusion of adenovirus vector-mediated reporter gene in the transplanted mouse heart. J Thorac Cardiovasc Surg 1996; 111: 246-252.
9. Donahue JK, Kikkawa K, Johns DC, Marban E, Lawrence JH. Ultrarapid, highly efficient viral gene transfer to the heart. Proc Natl Acad Sci U S A 1997; 94: 4664-4668.
10. Lee LY, Patel SR, Hackett NR, et al. Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121. Ann Thorac Surg 2000; 69: 14-23; discussion 23-24.
11. Sen L, Hong YS, Luo H, Cui G, Laks H. Efficiency, efficacy, and adverse effects of adenovirus vs. liposome-mediated gene therapy in cardiac allografts. Am J Physiol Heart Circ Physiol 2001; 281: H1433-1441.
12. Pellegrini C, Jeppsson A, Taner CB, et al. Highly efficient ex vivo gene transfer to the transplanted heart by means of hypothermic perfusion with a low dose of adenoviral vector. J Thorac Cardiovasc Surg 2000; 119: 493-500.
13. Griscelli F, Belli E, Opolon P, et al. Adenovirus-mediated gene transfer to the transplanted piglet heart after intracoronary injection. J Gene Med 2003; 5: 109-119.
14. Graham FL, Prevec L. Manipulation of adenovirus vectors. In Methods in Molecular Biology, EJ Murray (ed). Humana Press: Totowa, 1991; 109-128.
15. Wright MJ, Rosenthal E, Stewart L, et al. beta-Galactosidase staining following intracoronary infusion of cationic liposomes in the in vivo rabbit heart is produced by microinfarction rather than effective gene transfer: a cautionary tale. Gene Ther 1998; 5: 301-308.
16. Persson R, Wohlfart C, Svensson U, Everitt E. Virus-receptor interaction in the adenovirus system: characterization of the positive cooperative binding of virions on HeLa cells. J Virol 1985; 54: 92-97.
17. Wickham TJ, Filardo EJ, Cheresh DA, Nemerow GR. Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization. J Cell Biol 1994; 127: 257-264.
18. Jahania MS, Sanchez JA, Narayan P, Lasley RD, Mentzer RM Jr. Heart preservation for transplantation: principles and strategies. Ann Thorac Surg 1999; 68: 1983-1987.
19. McLaren AJ, Friend PJ. Trends in organ preservation. Transpl Int 2003; 16: 701-708.
20. March KL, Woody M, Mehdi K, et al. Efficient in vivo catheter-based pericardial gene transfer mediated by adenoviral vectors. Clin Cardiol 1999; 22: 123-29.
21. Boekstegers P, von Degenfeld G, Giehrl W, et al. Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins. Gene Ther 2000; 7: 232-240.
22. Emani SM, Shah AS, Bowman MK, et al. Catheter-based intracoronary myocardial adenoviral gene delivery: importance of intraluminal seal and infusion flow rate. Mol Ther 2003; 8: 306-313.
23. Davidson MJ, Jones JM, Emani SM, et al. Cardiac gene delivery with cardiopulmonary bypass. Circulation 2001; 104: 131-133.
24. Garcia-Dorado D, Oliveras J. Myocardial oedema: a preventable cause of reperfusion injury? Cardiovasc Res 1993; 27: 1555-1563.
25. Abunasra HJ, Smolenski RT, Yap J, et al. Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation. J Thorac Cardiovasc Surg 2003; 125: 998-1006.
26. Tevaearai HT, Eckhart AD, Shotwell KF, Wilson K, Koch WJ. Ventricular dysfunction after cardioplegic arrest is improved after myocardial gene transfer of a beta-adrenergic receptor kinase inhibitor. Circulation 2001; 104: 2069-2074.
27. Yang Z, Rostami S, Koeberlein B, Barker CF, Naji A. Cardiac allograft tolerance induced by intra-arterial infusion of recombinant adenoviral CTLA4Ig. Transplantation 1999; 67: 1517-1523.
28. Guillot C, Mathieu P, Coathalem H, et al. Tolerance to cardiac allografts via local and systemic mechanisms after adenovirus-mediated CTLA4Ig expression. J Immunol 2000; 164: 5258-5268.
29. David A, Chetritt J, Guillot C, et al. Interleukin-10 produced by recombinant adenovirus prolongs survival of cardiac allografts in rats. Gene Ther 2000; 7: 505-510.
30. Zuo Z, Wang C, Carpenter D, et al. Prolongation of allograft survival with viral IL-10 transfection in a highly histoincompatible model of rat heart allograft rejection. Transplantation 2001; 71: 686-691.
31. Guillot C, Guillonneau C, Mathieu P, et al. Prolonged blockade of CD40-CD40 ligand interactions by gene transfer of CD40Ig results in long-term heart allograft survival and donor-specific hyporesponsiveness, but does not prevent chronic rejection. J Immunol 2002; 168: 1600-1609.
32. Braudeau C, Bouchet D, Tesson L, et al. Induction of long-term cardiac allograft survival by heme oxygenase-1 gene transfer. Gene Ther 2004; 11: 701-710.
33. Hattori T, Shimokawa H, Higashi M, et al. Long-term treatment with a specific Rho-kinase inhibitor suppresses cardiac allograft vasculopathy in mice. Circ Res 2004; 94: 46-52.