Efficient in vivo catheter-based pericardial gene transfer mediated by adenoviral vectors

Clinical Cardiology

Volumn 22, Issue 1 SUPPL., 1999, Pages

  March, Keith L ^b,e   Woody, Michael ^a   Mehdi, Khawar ^a   Zipes, Douglas P ^a   Brantly, Mark ^c   Trapnell, Bruce C ^d  

^a INDIANA UNIVERSITY   (United States)

^b RICHARD L ROUDEBUSH VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; BETA GALACTOSIDASE; LUCIFERASE; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CORONARY ARTERY DISEASE; DOG; GENE EXPRESSION; GENE TRANSFER; NONHUMAN; PERICARDIUM;

EID: 0032928509     PISSN: 01609289     EISSN: None     Source Type: Journal    
DOI: 10.1002/clc.4960221308     Document Type: Conference Paper

References (45)

1. Isner J, Walsh K, Symes J, Pieczek A, Takeshita S, Lowry J, Rossow S, Rosenfield K, Weir L, Brogi E, Schainfeld R: Arterial gene therapy for therapeutic angiogenesis in patients with peripheral artery disease. Circulation 1995;91:2687-2692
2. Nabel EG, Plautz GE, Nabel GJ: Recombinant growth factor gene expression in vascular cells in vivo. Ann NY Acad Sci 1994;714: 247-252
3. Lemarchand P, Jones M, Yamada I, Crystal RG: In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circ Res 1992;72: 1132-1138
4. Lee SW, Trapnell BC, Rade JJ, Virmani R, Dichek DA: In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries. Circ Res 1993;73:797-807
5. Guzman RJ, Lemarchand P, Crystal RG, Epstein SE, Finkel T: Efficient gene transfer into myocardium by direct injection of adenovirus vectors. Circulation 1993;88:2838-2847
6. March KL, Madison JE, Trapnell BC: Pharmacokinetics of adenoviral vector-mediated gene delivery to vascular smooth muscle cells: Modulation by poloxamer 407 and implications for cardiovascular gene therapy. Hum Gene Ther 1995;6:41-43
7. Isner J, Van Belle E, Maillard L, Rivard A, Fabre JE: Effects of poloxamer 407 on transfection time and percutaneous adenovirus-mediated gene transfer in native and stented vessels. Hum Gene Ther 1998;1:9(7):1013-1024
8. Isner J, Feldman LJ, Pastore CJ, Aubailly N. Kearney M: Improved efficiency of arterial gene transfer by use of poloxamer 407 as a vehicle for adenoviral vectors. Gene Ther 1997;4(3): 189-198
9. March KL, Trapnell B: Pharmacokinetics of Local Vector Delivery to Vascular Tissues: Implications for Efficiency and Localization, p. 477-493. Norwell, Mass.: Kluwer Academic Press, 1997
10. Barr E, Carroll J, Kalynych AM, Tripathy SK, Kozasrsky K, Wilson JM, Leiden JM: Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. Gene Ther 1994; 1:51-58
11. Giordano FJ, Ping P, McKirnan MD, Nozaki S, DeMaria AN, Dillmann WH, Mathieu-Costello O, Hammond HK: Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart. Nature Med 1995;2(5):534-539
12. Crystal RG, Mack CA, Patel SR, Schwarz EA, Zanzonico P, Hahn RT, Ilercil A, Devereux RB, Goldsmith SJ, Christian TR, Sanborn TA, Kovesdi I, Hackett N, Isom OW, Rosengart TK: Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart. J Thorac Cardiol Surg 1998;115(1):168-176
13. Kass-Eisler A, Falck-Pedersen E, Alvira M, Rivera J, Buttrick PM, Wittenberg BA, Cipriani L, Leinwand LA: Quantitative determination of adenovirus-mediated gene delivery in rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci USA 1993;90:11498-11502
14. French BA, Mazur W, Geske RS, Bolli R: Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors. Circulation 1994;90:2414-2424
15. Koh GY, Soonpaa MH, Klug MG, Pride HP, Cooper BJ, Zipes DP, Field LJ: Stable fetal cardiomyocyte grafts in the hearts of dystrophic mice and dogs. J Clin Invest 1995;96:2034-2042
16. March KL, Woody M, Mehdi K, Zipes DP, Brantley M, Trapnell BL: High efficiency adenovirus-mediated pericardial gene transfer in vivo (abstr). J Am Coll Cardiol 1996;27(2):31A
17. Laubach V, Ryan J, Brantly M: Characterization of a human alpha 1-antitripsin null allele involving aberrant mRNA splicing. Hum Mol Genetics 1993;2:1001-1005
18. Mittereder N, Yei S, Bachurski C, Cuppoletti J, Whitsett JA, Tolstoshev P, Trapnell BC: Evaluation of the efficacy and safety of in vitro, adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA. Hum Gene Ther 1994;5:719-731
19. Miyazaki T, Pride HP, Zipes DP: Prostaglandins in the pericardial fluid modulate neural regulation of cardiac electrophysiologic properties. Circ Res 1990;66:163-175
20. Dannenburg AM, Suga M, Adams DO, Edelson PJ, Koren MS: Methods for Studying Mononuclear Phagocytes, p. 375-396. New York: Academic Press, 1981
21. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principal of protein-dye binding. Anal Biochem 1976;72:248-254
22. Hughes D, Elliott D, Washabau R, Keuppers F: Effects of age, sex, reproductive status, and hospitalization on serum alpha 1-antitripsin concentration in dogs. Am J Vet Res 1995;56:568-572
23. Heistad DD, Lamping KG, Rios CD, Chun JA, Ooboshi H, Davidson BL: Intrapericardial administration of adenovirus for gene transfer. Am J Phys 1997;272(1 Pt 2):H310-317
24. Santamore WP, Constantinescu MS, Bogen D, Johnston WE: Non-uniform distribution of normal pericardial fluid. Basic Res Cardiol 1990;85:541-549
25. Yei, S, Mittereder N, Tang K, O'Sullivan C, Trapnell BC: Adenovirus-mediated gene transfer for cystic fibrosis: Quantitative evaluation of repeated in vivo vector administration to the lung. Gene Ther 1994;1:192-200
26. Ayers G, Rho TH, Pride HP, Zipes DP: Amiodarone: Electrophysiological effects when instilled into the pericardial sac. J Cardiol Electro 1996;7(8):713-721
27. Willerson JT, Igo SR, Yao SK, Ober JC, Maoris MP, Ferguson JJ: Localized administration of sodium nitroprusside enhances its protection against platelet aggregation in stenosed and injured coronary arteries. Texas Heart Inst J 1996;23(1):1-8
28. Back SH, Keefer LK, Mehdi K, March KL: Intrapericardial nitric oxide donor reduces neointimal and adventitial thickening following porcine coronary overstretch (abstr). J Am Call Cardiol 1997;51A
29. Roessler BJ, Allen ED, Wilson JM, Hartman JW, Davidson BL: Adenoviral-mediated gene transfer to rabbit synovium in vivo. J Clin Invest 1993;92:1085-1092
30. Yang Y, Raper SE, Cohn JA, Engelhardt JF: An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer. Proc Natl Acad Sci USA 1993;90,4601-4605
31. Smythe WR, Hwang HC, Amin KM, Eck SL, Davidson BL, Wilson JM, Kaiser LR, Albelda SM: Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: An effective in vitro drug sensitization system. Cancer Res 1994;54:2055-2069
32. Oldfield EH, Ram Z, Chiang Y, Blaese RM: Intrathecal gene therapy for the treatment of leptomeningeal carcinomatosis. Hum Gene Ther 1995;6:55-85
33. Li T, Adamian M, Roof DJ, Berson EL, Dryja TP, Roessler BJ, Davidson BL: In vivo transfer of a reporter gene to the retina mediated by an adenoviral vector. Inv Ophthal Vis Sci 1994;35: 2543-2549
34. Setoguchi Y, Jaffe HA, Chu CS, Crystal RG: Intrapericardial in vivo gene therapy to delivery α1-antitrypsin to the system. Am J Respir Cell Mol Biol 1994:10:369-377
35. Jaffe HA, Danel C, Longenecker G, Merzger M, Setoguchi Y, Rosenfeld MS, Gant TW, Thorgeirsson SS, Stratford-Perricaudet LS, Perricaudet M, Pavirani A, Lecocq J-P, Crystal RG: Adenovirus-mediated in vivo gene transfer and expression in normal rat liver. Nat Genet 1992;1:368-371
36. Page E, Upshaw-Earley J, Goings G: Permeability of rat atrial endocardium, epicardium, and myocardium to large molecules. Stretch-dependent effects. Circ Res 1992;71:159-173
37. March KL, Stoll HP, Szabo A: Sustained transmyocardial loading with bFGF following single intrapericardial delivery: Local kinetics and tissue penetration. Circulation 1998:98(17):I-399
38. Harada K, Grossman W, Friedman M, Edelman ER, Prasad PV, Keighley CS, Manning WJ, Sellke FW, Simons M: Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts. J Clin Invest 1994;94:623-630
39. Amano J, Suzuki A, Sunamori M, Shichiri M, Marumo F: Atrial natriuretic peptide in the pericardial fluid of patients with heart disease. Clin Sci 993;85:165-168
40. Darsinos JT, Samouilidou EC, Krumholz B, Kontoyanni M, Pistevos AK, Karli JN, Theodorakis MG, Levis GM, Moulopoulos SD: Distribution of lidocaine and digoxin in heart tissues and aorta following intrapericardial administration. Intern J Clin Pharm, Ther, and Toxic 1993;31:611-615
41. Kohnoe S, Maehara Y, Takahashi I, Saiton A, Okada Y, Sugimachi K: Intrapericardial mitomycin C for the management of malignant pericardial effusion secondary to gastric cancer: Case report and review. Chemotherapy 1994;4057-4060
42. Banai S, Jaklitsch MT, Shou M, Lazarous DF, Scheinowitz M, Biro S, Epstein SE, Unger EF: Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs. Circulation 1994;89:2183-2189
43. Unger EF, Banai S, Shou M, Lazarous DF, Jaklitsch MT, Scheinowitz M, Correa R, Klingbeil C, Epstein SE: Basic fibroblast growth factor enhances myocardial collateral flow in a canine model. Am J Physiol 1994;266 (Heart Circ. Physiol 35): H1588-H1595
44. Simons M, Lopez JJ, Edelman ER, Stamler A, Hibberd MG, Prasad P, Caputo RP, Carrozza JP, Douglas PS, Sellke FW: Basic fibroblast growth factor in a porcine model of chronic myocardial ischemia: A comparison of angiographic, echocardiographic and coronary flow parameters. J Pharm Exper Ther 1997;282(1):385-390
45. Simons M, Harada K, Friedman M, Lopez JJ, Wang SY, Li J, Prasad PV, Pearlman JD, Edelman ER, Sellke FW: Vascular endothelial growth factor administration in chronic myocardial ischemia. Am J Phys 1996;270(5 Pt 2):H1791-802