Distinct signaling pathways are involved in Hypoxia- and IL-1-induced VEGF expression in human articular chondrocytes

Journal of Orthopaedic Research

Volumn 24, Issue 7, 2006, Pages 1544-1554

  Murata, Minako ^a,b   Yudoh, Kazuo ^a   Nakamura, Hiroshi ^a   Kato, Tomohiro ^a   Inoue, Kazuhiko ^b   Chiba, Junji ^b   Nishioka, Kusuki ^a   Masuko Hongo, Kayo ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Chondrocytes; Hypoxia; Mitogen activated protein kinase; Osteoarthritis; Vascular endothelial growth factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; INCUBATION TIME; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; WESTERN BLOTTING;

AGED; ANOXIA; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-1; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; OSTEOARTHRITIS, KNEE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33746145655     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20168     Document Type: Article

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