Biglycan deficiency increases osteoclast differentiation and activity due to defective osteoblasts

Bone

Volumn 38, Issue 6, 2006, Pages 778-786

  Bi, Yanming ^a   Nielsen, Karina L ^b   Kilts, Tina M ^a   Yoon, Anne ^a   A Karsdal, Morten ^b   Wimer, Helen F ^c   Greenfield, Edward M ^d   Heegaard, Anne Marie ^c   Young, Marian F ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NORDIC BIOSCIENCE A S   (Denmark)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DEPARTMENT OF PALEOBIOLOGY   (United States)

Author keywords

Biglycan; ECM; Osteoclast; Osteolysis; Proteoglycan

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CALCITRIOL; LIPOPOLYSACCHARIDE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIGLYCAN DEFICIENCY; BONE MARROW; CALVARIA; CELL ACTIVITY; CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CELL STIMULATION; CONTROLLED STUDY; GENOTYPE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PROTEIN ANALYSIS; PROTEIN DEFECT; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SPLEEN; STEM CELL; WILD TYPE;

ANIMALS; BIGLYCAN; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOCLASTS; OSTEOPROTEGERIN; PROTEOGLYCANS; RANK LIGAND; SECRETORY LEUKOCYTE PEPTIDASE INHIBITOR; SKULL; TITANIUM;

EID: 33746013439     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.11.005     Document Type: Article

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