메뉴 건너뛰기




Volumn 37, Issue 1, 2006, Pages 55-63

HOXA11 mutation in amegakaryocytic thrombocytopenia with radio-ulnar synostosis syndrome inhibits megakaryocytic differentiation in vitro

Author keywords

Gene expression; Hematopoietic precursor; Homeobox gene; HOXA11; Megakaryocytic differentiation

Indexed keywords

GLUTATHIONE TRANSFERASE; LEUKEMIA INHIBITORY FACTOR; MUTANT PROTEIN; TRANSCRIPTION FACTOR;

EID: 33745960015     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2006.04.001     Document Type: Article
Times cited : (44)

References (38)
  • 1
    • 0030729371 scopus 로고    scopus 로고
    • Effects of HOX homeobox genes in blood cell differentiation
    • Magli M.C., Largman C., and Lawrence H.J. Effects of HOX homeobox genes in blood cell differentiation. J. Cell. Physiol. 173 2 (1997) 168-177
    • (1997) J. Cell. Physiol. , vol.173 , Issue.2 , pp. 168-177
    • Magli, M.C.1    Largman, C.2    Lawrence, H.J.3
  • 3
    • 0031031880 scopus 로고    scopus 로고
    • Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia
    • Thorsteinsdottir U., et al. Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia. Mol. Cell. Biol. 17 1 (1997) 495-505
    • (1997) Mol. Cell. Biol. , vol.17 , Issue.1 , pp. 495-505
    • Thorsteinsdottir, U.1
  • 4
    • 0028883628 scopus 로고
    • Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells
    • Lawrence H.J., et al. Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells. Exp. Hematol. 23 11 (1995) 1160-1166
    • (1995) Exp. Hematol. , vol.23 , Issue.11 , pp. 1160-1166
    • Lawrence, H.J.1
  • 5
    • 0029954818 scopus 로고    scopus 로고
    • The role of HOX homeobox genes in normal and leukemic hematopoiesis
    • Lawrence H.J., et al. The role of HOX homeobox genes in normal and leukemic hematopoiesis. Stem Cells 14 3 (1996) 281-291
    • (1996) Stem Cells , vol.14 , Issue.3 , pp. 281-291
    • Lawrence, H.J.1
  • 6
    • 0030747208 scopus 로고    scopus 로고
    • Homeobox genes in embryogenesis and pathogenesis
    • Mark M., Rijli F.M., and Chambon P. Homeobox genes in embryogenesis and pathogenesis. Pediatr. Res. 42 4 (1997) 421-429
    • (1997) Pediatr. Res. , vol.42 , Issue.4 , pp. 421-429
    • Mark, M.1    Rijli, F.M.2    Chambon, P.3
  • 7
    • 0028079924 scopus 로고
    • Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells
    • Sauvageau G., et al. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc. Natl. Acad. Sci. U. S. A. 91 25 (1994) 12223-12227
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , Issue.25 , pp. 12223-12227
    • Sauvageau, G.1
  • 8
    • 18444411370 scopus 로고    scopus 로고
    • Activation of stem-cell specific genes by HOXA9 and HOXA10 homeodomain proteins in CD34+ human cord blood cells
    • Ferrell C.M., et al. Activation of stem-cell specific genes by HOXA9 and HOXA10 homeodomain proteins in CD34+ human cord blood cells. Stem Cells 23 (2005) 644-655
    • (2005) Stem Cells , vol.23 , pp. 644-655
    • Ferrell, C.M.1
  • 9
    • 0029947439 scopus 로고    scopus 로고
    • Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro
    • Helgason C.D., et al. Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro. Blood 87 7 (1996) 2740-2749
    • (1996) Blood , vol.87 , Issue.7 , pp. 2740-2749
    • Helgason, C.D.1
  • 10
    • 0037023544 scopus 로고    scopus 로고
    • HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors
    • Kyba M., Perlingeiro R.C., and Daley G.Q. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell 109 1 (2002) 29-37
    • (2002) Cell , vol.109 , Issue.1 , pp. 29-37
    • Kyba, M.1    Perlingeiro, R.C.2    Daley, G.Q.3
  • 11
    • 0028103855 scopus 로고
    • Homeodomain-DNA recognition
    • Gehring W.J., et al. Homeodomain-DNA recognition. Cell 78 2 (1994) 211-223
    • (1994) Cell , vol.78 , Issue.2 , pp. 211-223
    • Gehring, W.J.1
  • 12
    • 0028947525 scopus 로고
    • Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins
    • Chang C.P., et al. Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes Dev. 9 (1995) 663-674
    • (1995) Genes Dev. , vol.9 , pp. 663-674
    • Chang, C.P.1
  • 13
    • 0029865897 scopus 로고    scopus 로고
    • Hox homeodomain proteins exhibit selective complex stabilites with Pbx and DNA
    • Shen W.F., et al. Hox homeodomain proteins exhibit selective complex stabilites with Pbx and DNA. Nucleic Acid Res. 24 5 (1996) 898-906
    • (1996) Nucleic Acid Res. , vol.24 , Issue.5 , pp. 898-906
    • Shen, W.F.1
  • 14
    • 0030848853 scopus 로고    scopus 로고
    • AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins
    • Shen W.F., et al. AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Mol. Cell. Biol. 17 11 (1997) 6448-6458
    • (1997) Mol. Cell. Biol. , vol.17 , Issue.11 , pp. 6448-6458
    • Shen, W.F.1
  • 15
    • 0032964378 scopus 로고    scopus 로고
    • HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells
    • Shen W.F., et al. HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells. Mol. Cell. Biol. 19 4 (1999) 3051-3061
    • (1999) Mol. Cell. Biol. , vol.19 , Issue.4 , pp. 3051-3061
    • Shen, W.F.1
  • 16
    • 0029939199 scopus 로고    scopus 로고
    • Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus
    • Chang C.P., et al. Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus. Mol. Cell. Biol. 16 4 (1996) 1734-1745
    • (1996) Mol. Cell. Biol. , vol.16 , Issue.4 , pp. 1734-1745
    • Chang, C.P.1
  • 17
    • 0030929326 scopus 로고    scopus 로고
    • The Abd-like Hoxx homeodomain proteins can be subdivided by the ability to form complexes with Pbx1a on a novel DNA target
    • Shen W.F., et al. The Abd-like Hoxx homeodomain proteins can be subdivided by the ability to form complexes with Pbx1a on a novel DNA target. J. Biol. Chem. 272 13 (1997) 8198-8206
    • (1997) J. Biol. Chem. , vol.272 , Issue.13 , pp. 8198-8206
    • Shen, W.F.1
  • 18
    • 0036534442 scopus 로고    scopus 로고
    • Functional comparison of the Hoxa 4, Hoxa 10, and Hoxa 11 homeoboxes
    • Zhao Y., and Potter S.S. Functional comparison of the Hoxa 4, Hoxa 10, and Hoxa 11 homeoboxes. Dev. Biol. 244 1 (2002) 21-36
    • (2002) Dev. Biol. , vol.244 , Issue.1 , pp. 21-36
    • Zhao, Y.1    Potter, S.S.2
  • 19
    • 0033662329 scopus 로고    scopus 로고
    • Amegakaryocytic thrombocytopenia and radio-ulna synostosis are associated with HOXA11 mutation
    • Thompson A., and Nguyen L.T. Amegakaryocytic thrombocytopenia and radio-ulna synostosis are associated with HOXA11 mutation. Nat. Genet. 26 (2000) 397-398
    • (2000) Nat. Genet. , vol.26 , pp. 397-398
    • Thompson, A.1    Nguyen, L.T.2
  • 20
    • 0034936465 scopus 로고    scopus 로고
    • Congenital thrombocytopenia and radio-ulnar synostosis: a new familial syndrome
    • Thompson A.A., et al. Congenital thrombocytopenia and radio-ulnar synostosis: a new familial syndrome. Br. J. Haematol. 113 4 (2001) 866-870
    • (2001) Br. J. Haematol. , vol.113 , Issue.4 , pp. 866-870
    • Thompson, A.A.1
  • 21
    • 0028048369 scopus 로고
    • Generation of lymphohematopoietic cells from embryonic stem cells in culture
    • Nakano T., Kodama H., and Honjo T. Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science 265 5175 (1994) 1098-1101
    • (1994) Science , vol.265 , Issue.5175 , pp. 1098-1101
    • Nakano, T.1    Kodama, H.2    Honjo, T.3
  • 22
    • 0033557571 scopus 로고    scopus 로고
    • Maturation of embryonic stem cells into endothelial cells in an in vitro model of vasculogenesis
    • Hirashima M., et al. Maturation of embryonic stem cells into endothelial cells in an in vitro model of vasculogenesis. Blood 93 4 (1999) 1253-1263
    • (1999) Blood , vol.93 , Issue.4 , pp. 1253-1263
    • Hirashima, M.1
  • 23
    • 0031833476 scopus 로고    scopus 로고
    • Progressive lineage analysis by cell sorting and culture identifies FLK1 + VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages
    • Nishikawa S.I., et al. Progressive lineage analysis by cell sorting and culture identifies FLK1 + VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development 125 9 (1998) 1747-1757
    • (1998) Development , vol.125 , Issue.9 , pp. 1747-1757
    • Nishikawa, S.I.1
  • 24
    • 0029008293 scopus 로고
    • Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif
    • Phelan M.L., Rambaldi I., and Featherstone M.S. Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif. Mol. Cell. Biol. 15 8 (1995) 3989-3997
    • (1995) Mol. Cell. Biol. , vol.15 , Issue.8 , pp. 3989-3997
    • Phelan, M.L.1    Rambaldi, I.2    Featherstone, M.S.3
  • 25
    • 0034992579 scopus 로고    scopus 로고
    • Origin of hematopoietic progenitors during embryogenesis
    • Ogawa M., et al. Origin of hematopoietic progenitors during embryogenesis. Int. Rev. Immunol. 20 1 (2001) 21-44
    • (2001) Int. Rev. Immunol. , vol.20 , Issue.1 , pp. 21-44
    • Ogawa, M.1
  • 26
    • 18244403994 scopus 로고    scopus 로고
    • SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast, but not for its development
    • D'Souza S.L., Elefanty A.G., and Keller G. SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast, but not for its development. Blood 105 10 (2005) 3862-3870
    • (2005) Blood , vol.105 , Issue.10 , pp. 3862-3870
    • D'Souza, S.L.1    Elefanty, A.G.2    Keller, G.3
  • 27
    • 18744366334 scopus 로고    scopus 로고
    • Hox regulation of normal and leukemic hematopoietic stem cells
    • Abramovich C., and Humphries R.K. Hox regulation of normal and leukemic hematopoietic stem cells. Curr. Opin. Hematol. 12 3 (2005) 210-216
    • (2005) Curr. Opin. Hematol. , vol.12 , Issue.3 , pp. 210-216
    • Abramovich, C.1    Humphries, R.K.2
  • 28
    • 0031773463 scopus 로고    scopus 로고
    • Definition of the transcriptional activation domains of three human HOX proteins depends on the DNA-binding context
    • Vigano M.A., et al. Definition of the transcriptional activation domains of three human HOX proteins depends on the DNA-binding context. Mol. Cell. Biol. 18 11 (1998) 6201-6212
    • (1998) Mol. Cell. Biol. , vol.18 , Issue.11 , pp. 6201-6212
    • Vigano, M.A.1
  • 29
    • 0032857094 scopus 로고    scopus 로고
    • Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does not inhibit differentiation
    • Lerga A., et al. Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does not inhibit differentiation. Cell Growth Differ. 10 9 (1999) 639-654
    • (1999) Cell Growth Differ. , vol.10 , Issue.9 , pp. 639-654
    • Lerga, A.1
  • 30
    • 0031000626 scopus 로고    scopus 로고
    • Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase
    • Whalen A.M., et al. Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase. Mol. Cell. Biol. 17 4 (1997) 1947-1958
    • (1997) Mol. Cell. Biol. , vol.17 , Issue.4 , pp. 1947-1958
    • Whalen, A.M.1
  • 31
    • 1942518374 scopus 로고    scopus 로고
    • Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation
    • Vijapurkar U., et al. Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation. Mol. Cell. Biol. 24 9 (2004) 3827-3837
    • (2004) Mol. Cell. Biol. , vol.24 , Issue.9 , pp. 3827-3837
    • Vijapurkar, U.1
  • 32
    • 0037184004 scopus 로고    scopus 로고
    • SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells
    • Eklund E.A., et al. SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells. J. Biol. Chem. 277 39 (2002) 36878-36888
    • (2002) J. Biol. Chem. , vol.277 , Issue.39 , pp. 36878-36888
    • Eklund, E.A.1
  • 33
    • 0034733573 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon gamma-induced differentiation of myeloid leukemia cell lines
    • Eklund E.A., Jalava A., and Kakar R. Tyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon gamma-induced differentiation of myeloid leukemia cell lines. J. Biol. Chem. 275 26 (2000) 20117-20126
    • (2000) J. Biol. Chem. , vol.275 , Issue.26 , pp. 20117-20126
    • Eklund, E.A.1    Jalava, A.2    Kakar, R.3
  • 34
    • 28444455240 scopus 로고    scopus 로고
    • Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells
    • Lawrence H.J., et al. Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood 106 12 (2005) 3988-3994
    • (2005) Blood , vol.106 , Issue.12 , pp. 3988-3994
    • Lawrence, H.J.1
  • 35
    • 22044453432 scopus 로고    scopus 로고
    • Control of self-renewal and differentiation of hematopoietic stem cells: HOXB4 on the threshold
    • Klump H., Schiedlmeier B., and Baum C. Control of self-renewal and differentiation of hematopoietic stem cells: HOXB4 on the threshold. Ann. N. Y. Acad. Sci. 1044 (2005) 6-15
    • (2005) Ann. N. Y. Acad. Sci. , vol.1044 , pp. 6-15
    • Klump, H.1    Schiedlmeier, B.2    Baum, C.3
  • 36
    • 0038246245 scopus 로고    scopus 로고
    • Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4
    • Bjornsson J.M., et al. Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4. Mol. Cell. Biol. 23 11 (2003) 3872-3883
    • (2003) Mol. Cell. Biol. , vol.23 , Issue.11 , pp. 3872-3883
    • Bjornsson, J.M.1
  • 37
    • 10744230627 scopus 로고    scopus 로고
    • The transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic cells
    • Dorsam S.T., et al. The transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic cells. Blood 103 5 (2004) 1676-1684
    • (2004) Blood , vol.103 , Issue.5 , pp. 1676-1684
    • Dorsam, S.T.1
  • 38
    • 0037062407 scopus 로고    scopus 로고
    • Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney
    • Valerius M.T., et al. Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney. Proc. Natl. Acad. Sci. U. S. A. 99 12 (2002) 8090-8095
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , Issue.12 , pp. 8090-8095
    • Valerius, M.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.