Calcium salicylate-mediated apoptosis in human HT-1080 fibrosarcoma cells

Cell Proliferation

Volumn 39, Issue 4, 2006, Pages 249-260

  Mahdi, J G ^a,c   Alkarrawi, M A ^a   Mahdi, A J ^b   Bowen, I D ^a   Humam, D ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c NONE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CALCIUM SALICYLATE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; SALICYLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASSAY; CYTOLOGY; HUMAN; HUMAN CELL; IMMUNOCHEMISTRY; MORPHOLOGY; PROTEIN EXPRESSION; TUMOR GROWTH; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; FIBROSARCOMA; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INDICATORS AND REAGENTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; SALICYLATES; TETRAZOLIUM SALTS; THIAZOLES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33745844095     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2006.00390.x     Document Type: Article

References (55)

1. Aguilar-Santelises M, Rottenberg ME, Lewin N, Mellstedt H, Jondal M (1996) Bcl-2 Bax and p53 expression in B-CLL in relation to in vitro survival and clinical progression. Int. J. Cancer 69, 114-119.
2. Azmi S, Dhawan D, Singh N (1996) Calcium ionophore A 23187 induces apoptotic cell death in rat thymocytes. Cancer Lett. 107, 97-103.
3. 2 and Bax in neuroendocrine lung tumors. Am. J. Pathol. 149, 1941-1952.
4. Brooks G, Yu XM, Wang Y, Crabbe MJ, Shattock MJ, Harper JV (2003) Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle. J. Pharm. Pharmacol. 55, 519-526.
5. Chresta CM, Masters JRW, Hickman JA (1996) Hypersensitivity of testicular tumors to etoposide-induced apoptosis is associated with functional p53 and high Bax/bcl-2 ratio. Cancer Res. 56, 1834-1841.
6. Claudia O (2003) Aspirin protects against cancer of the upper aerodigestive tract. Lancet Oncol. 4, 200.
7. Eguchi-Ishimae M, Eguchi M, Ishii E, Miyazaki S, Ueda K, Kamada N, Mizutani S (2001) Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals. Blood 97, 737-743.
8. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825.
9. Frantz B, O'Neill EA (1995) The effect of sodium salicylate and aspirin on NF-B. Science 270, 2017-2018.
10. Funkhouser EM, Sharp GB (1995) Aspirin and reduced risk of esophageal carcinoma. Cancer 76, 1116-1119.
11. Gazzaniga P, Gradilone A, Vercillo R, Gandini P, Silvestri I, Napolitano M, Vincenzoni A, Gallucci M, Agliano AM (1996) Bcl-2/Bax mRNA expression ratio as prognostic factor in low-grade urinary bladder cancer. Int. J. Cancer 69, 100-104.
12. Giardina C, Boulares H, Inan MS (1999) NSAIDs and butyrate sensitize a human colorectal cancer cell line to TNF-alpha and Fas ligation: the role of reactive oxygen species. Biochim. Biophys. Acta. 1448, 425-438.
13. Green DR (2000) Apoptotic pathways: paper wraps stone blunts scissors. Cell 102, 1-4.
14. Hector AA, Suzane I, Williams SR, Denis C, Jeanne LB (2001) Aspirin effects on endometrial cancer cell growth. Obstet. Gynecol. 97, 423-427.
15. Hial V, De Mello MC, Horakova Z, Beaven MA (1977) Antiproliferative activity of anti-inflammatory drugs in two mammalian cell culture lines. J. Pharmacol. Exp. Ther. 202, 446-454.
16. Huang DC, Strasser A (2000) BH3-only proteins - essential initiators of apoptotic cell death. Cell 103, 839-842.
17. Husain SS, Szabo IL, Pai R, Soreghan B, Jones MK, Tarnawski AS (2001) MAPK (ERK2) kinase- a key target for NSAIDs-induced inhibition of gastric cancer cell proliferation and growth. Life Sci. 69, 3045-3054.
18. Jaattela M (1999) Escaping cell death: survival proteins in cancer. Exp. Cell Res. 248, 30-43.
19. Karlsson JO, Ostwald K, Kabjorn C, Andersson M (1994) A method for protein assay in Laemmli buffer. Anal. Biochem. 219, 144-146.
20. Kuo P-L, Lin T-C, Lin C-C (2002) The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines. Life Sci. 71, 1879-1892.
21. Mahdi JG, Al Karaawi M, Pepper CJ, Bowen ID (2005) Sub-milimolar concentrations of the novel phenolic compound JMC-18 induces apoptosis in the human HT-1080 fibrosarcoma cell line. European Cell Proliferation Society 27th meeting, Queen Mary, University of London 7th-10th September 2005.
22. Mahdi JG, Mahdi AJ, Mahdi AJ, Bowen ID (2006) The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential. Cell Prolif. 39, 147-155.
23. Marra DE, Liao JK (2001) Salicylates and vascular smooth muscle cells proliferation: molecular mechanism for cell cycle arrest. Trends Cardiovasc. Med. 11, 339-344.
24. KiP1. Circulation 102, 2124-2130.
25. Masmoudi Chevalier TL, Sabatier L, Soria JC (2004) Cyclooxygenase 2 inhibitors and cancer chemoprevention. Bull. Cancer Suppl. 91 (2): S77-S84.
26. Mayer F, Stoop H, Scheffer GL, Scheper R, Oosterhuis JW, Looijenga LH, Bokemeyer C (2003) Molecular determinants of treatment response in human germ cell tumors. Clin. Cancer Res. 9, 767-773.
27. 2 on proliferation and apoptosis of epithelial ovarian cancer cells. J. Soc. Gynecol. Invest. 9, 168-173.
28. Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates cell apoptosis. Cell 74, 609-619.
29. Patrono C, Coller B, Fitzgerald GA, Hirsh J, Roth G (2004) Platelet-active drugs: the relationships among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic. Ther. Chest. 126, 234S-264S.
30. Perugini RA, McDade TB, Vittimberga FJ, Duffy AJ, Callery MP (2000) Sodium salicylate inhibits proliferation and induces G1 cell cycle arrest in human pancreatic cancer cell lines. J. Gastrointest. Surg. 4, 24-33.
31. Raz A (2002) Is inhibition of cyclooxygenase required for the anti-tumorigenic effects of nonsterolidal: anti-inflammatory drugs (NSAIDs)? In vitro versus in vivo results and the relevance for the prevention and treatment of cancer. Biochem. Pharmacol. 63, 343-347.
32. Reed JC (2000) Mechanisms of apoptosis. Am. J. Pathol. 157, 1415-1430.
33. Rogers HW, Callery MP, Deck B, Unanue ER (1996) Listeria monocytogenes induces apoptosis of infected hepatocytes. J. Immunol. 156, 679-684.
34. Ruschoff J, Wallinger S, Dietmaie W, Bocker T, Brockhoff G, Hofstadte RF, Fishel R (1998) Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection. Proc. Natl. Acad. Sci. USA 95, 11301-11306.
35. Santini G, Sciulli MG, Marinacci R, Fusco O, Spoletini L, Pace A, Ricciardulli A, Natoli C, Procopio A, Maclouf J, Patrignani P (1999) Cyclooxygenase-independent induction of p21WAF-1/cip1, apoptosis and differentiation by L-745,337, a selective PGH synthase-2 inhibitor, and salicylate in HT-29 cells. Apoptosis 4, 151-162.
36. Sedlak TW, Oltvai ZN, Yang E, Wang K, Boise LH, Thompson CB, Korsmeyer SJ (1995) Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc. Natl. Acad. Sci. USA 92, 7834-7838.
37. Shiff SJ, Koutsos MI, Qiao L, Rigas B (1996) Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adeno carcinoma cells: effects on cell cycle and apoptosis. Exp. Cell Res. 222, 179-188.
38. Shimokawa T, Smith WL (1992) Prostaglandin endoperoxide synthase. The aspirin acetylation region. J. Biol. Chem. 267, 12387-12392.
39. Smith WL, Dewitt DL, Shimokawa T, Kraemer SA, Meade EA (1990) Molecular basis for the inhibition of prostanoid biosynthesis by nonsteroidal anti-inflammatory agents. Stroke 21, IV24-IV28.
40. Smith ML, Hawcroft G, Hull MA (2000) The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur. J. Cancer 36, 664-674.
41. Soini Y, Kinnula V, Kaarteenaho-Wiik R, Kurttila E, Linnainmaa K, Paakko P (1999) Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and Bax in malignant mesothelioma. Clin. Cancer Res. 5, 3508-3515.
42. Stark LA, Din FVN, Zwacka RM, Dunlop MG (2001) Aspirin induced activation of the NF-êB signalling pathway: a novel mechanism for aspirin mediated apoptosis in colon cancer cells. FASEB J. 15, 1273-1275.
43. CIP1/WAF1-independent pathways. Cancer Lett. 133, 77-82.
44. Vane JR, Botting RM (2003) The mechanism of action of aspirin. Thromb. Res. 110, 255-258.
45. Vaux DL, Aguila HL, Weissman IL (1992) Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell-mediated killing. Int. Immunol. 4, 821-824.
46. Walker PR, Sikorska M (1997) New aspects of the mechanism of DNA fragmentation in apoptosis. Biochem. Cell Biol. 75, 287-299.
47. Wong BCY, Zhu GH, Lam SK (1999) Aspirin induced apoptosis in gastric cancer cells. Biomed. Pharmacother. 53, 315-318.
48. Wu KK (2003) Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. Semin. Vasc. Med. 3, 107-1012.
49. Wyllie AH (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284, 555-556.
50. Wyllie AH, Beattie GJ, Hargreaves AD (1981) Chromatin changes in apoptosis. Histochem. J. 13, 681-692.
51. Xu X-M, Sansores-Garcia L, Chen X-M, Matijevic-Aleksic NM, Wu KK (1999) Suppression of inducible cyclooxygenase-2 gene transcription by aspirin and salicylate. Proc. Natl. Acad. Sci. USA 96, 5292-5297.
52. Yin MJ, Yamamoto Y, Gaynor RB (1998) The antiinflammatory agents aspirin and salicylate inhibit the activity of I (kappa) B kinase-beta. Nature 396, 77-80.
53. Yoneda K, Yamamoto T, Osaki T (1998) p53- and p21-independent apoptosis of squamous cell carcinoma cells induced by 5-fluorouracil and radiation. Oral Oncol. 34, 529-537.
54. Zhou XM, Chun B, Wong Y, Fan XM, Zhang HB, Kung MCM, Fan DM, Lam SK (2001) Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of Bax and Bak. Carcinogenesis 22, 1393-1397.
55. Zou H, Henzel WJ, Liu XA, Lutschg A, Wang X (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413.