메뉴 건너뛰기




Volumn 17, Issue 7, 2006, Pages 1979-1985

Nested N-terminal megalin fragments induce high-titer autoantibody and attenuated Heymann nephritis

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AUTOANTIBODY; COMPLEMENT COMPONENT C3; COMPLEMENT MEMBRANE ATTACK COMPLEX; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN G1; MEGALIN;

EID: 33745827421     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2005101144     Document Type: Article
Times cited : (19)

References (35)
  • 1
    • 0024475110 scopus 로고
    • Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor
    • Raychowdhury R, Niles J, McCluskey R, Smith J: Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor. Science 244: 1163-1165, 1989
    • (1989) Science , vol.244 , pp. 1163-1165
    • Raychowdhury, R.1    Niles, J.2    McCluskey, R.3    Smith, J.4
  • 2
    • 0028925427 scopus 로고
    • Role of receptor-associated 39-45kDa protein in active Heymann nephritis
    • Huang J, Makker S: Role of receptor-associated 39-45kDa protein in active Heymann nephritis. Kidney Int 47: 432-441, 1995
    • (1995) Kidney Int , vol.47 , pp. 432-441
    • Huang, J.1    Makker, S.2
  • 3
    • 0021331906 scopus 로고
    • Characterization of the antigen (gp600) of Heymann nephritis
    • Makker S, Singh A: Characterization of the antigen (gp600) of Heymann nephritis. Lab Invest 50: 287-293, 1984
    • (1984) Lab Invest , vol.50 , pp. 287-293
    • Makker, S.1    Singh, A.2
  • 4
    • 0005701635 scopus 로고
    • Biochemical analysis of nephritogenic rat kidney tubular membrane fraction (Fx1A)
    • Makker S, Singh A: Biochemical analysis of nephritogenic rat kidney tubular membrane fraction (Fx1A). Fed Proc 41: 1159, 1982
    • (1982) Fed Proc , vol.41 , pp. 1159
    • Makker, S.1    Singh, A.2
  • 5
    • 0004846480 scopus 로고
    • The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border
    • Kerjaschki D, Farquhar MG: The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border. Proc Natl Acad Sci U S A 79: 5557-5581, 1982
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 5557-5581
    • Kerjaschki, D.1    Farquhar, M.G.2
  • 6
    • 0027770948 scopus 로고
    • Epitope specificity of anti-gp330 autoantibodies determines the development of proteinuria in active Heymann nephritis
    • Van Leer EH, Ronco P, Verroust P, van der Wal AM, Hoedemaeker PJ, De Heer E: Epitope specificity of anti-gp330 autoantibodies determines the development of proteinuria in active Heymann nephritis. Am J Pathol 142: 821-829, 1993
    • (1993) Am J Pathol , vol.142 , pp. 821-829
    • Van Leer, E.H.1    Ronco, P.2    Verroust, P.3    Van Der Wal, A.M.4    Hoedemaeker, P.J.5    De Heer, E.6
  • 8
    • 0029021951 scopus 로고
    • Megalin (gp330) possesses an antigenic epitope capable of inducing passive Heymann nephritis independent of the nephritogenic epitope in receptor-associated protein
    • Orlando RA, Kerjaschki D, Farquhar MG: Megalin (gp330) possesses an antigenic epitope capable of inducing passive Heymann nephritis independent of the nephritogenic epitope in receptor-associated protein. J Am Soc Nephrol 6: 61-67, 1995
    • (1995) J Am Soc Nephrol , vol.6 , pp. 61-67
    • Orlando, R.A.1    Kerjaschki, D.2    Farquhar, M.G.3
  • 9
    • 0028019068 scopus 로고
    • Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family
    • Saito A, Pietromonaco S, Loo AK, Farquhar MG: Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family. Proc Natl Acad Sci U S A 91: 9725-9729, 1994
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 9725-9729
    • Saito, A.1    Pietromonaco, S.2    Loo, A.K.3    Farquhar, M.G.4
  • 10
    • 0029915185 scopus 로고    scopus 로고
    • Isolation of cDNAs encoding immunogenic regions of gp330, the autoantigen involved in Heymann nephritis
    • Luca ME, De Geus B, Sahali D, Bruijn JA, Verroust P, De Heer E: Isolation of cDNAs encoding immunogenic regions of gp330, the autoantigen involved in Heymann nephritis. Clin Exp Immunol 104: 312-317, 1996
    • (1996) Clin Exp Immunol , vol.104 , pp. 312-317
    • Luca, M.E.1    De Geus, B.2    Sahali, D.3    Bruijn, J.A.4    Verroust, P.5    De Heer, E.6
  • 11
    • 0029965469 scopus 로고    scopus 로고
    • Induction of Heymann nephritis with a gp330/megalin fusion protein
    • Raychowdhury R, Zheng G, Brown D, McCluskey RT: Induction of Heymann nephritis with a gp330/megalin fusion protein. Am J Pathol 148: 1613-1623, 1996
    • (1996) Am J Pathol , vol.148 , pp. 1613-1623
    • Raychowdhury, R.1    Zheng, G.2    Brown, D.3    McCluskey, R.T.4
  • 12
    • 0029774556 scopus 로고    scopus 로고
    • Mapping rat megalin: The second cluster of ligand binding repeats contains a 46-amino acid pathogenic epitope involved in the formation of immune deposits in Heymann nephritis
    • Saito A, Yamazaki H, Rader K, Nakatani A, Ullrich R, Kerjaschki D, Orlando RA, Farquhar MG: Mapping rat megalin: The second cluster of ligand binding repeats contains a 46-amino acid pathogenic epitope involved in the formation of immune deposits in Heymann nephritis. Proc Natl Acad Sci U S A 93: 8601-8605, 1996
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 8601-8605
    • Saito, A.1    Yamazaki, H.2    Rader, K.3    Nakatani, A.4    Ullrich, R.5    Kerjaschki, D.6    Orlando, R.A.7    Farquhar, M.G.8
  • 13
    • 0842300356 scopus 로고    scopus 로고
    • Conformation and glycosylation of a megalin fragment correlate with nephritogenicity in Heymann nephritis
    • Tramontano A, Makker SP: Conformation and glycosylation of a megalin fragment correlate with nephritogenicity in Heymann nephritis. J Immunol 172: 2367-2373, 2004
    • (2004) J Immunol , vol.172 , pp. 2367-2373
    • Tramontano, A.1    Makker, S.P.2
  • 14
    • 84984766757 scopus 로고    scopus 로고
    • Megalin and cubilin: Multifunctional endocytic receptors
    • Christensen EI, Birn H: Megalin and cubilin: Multifunctional endocytic receptors. Nat Rev Mol Cell Biol 3: 256-266, 2002
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 256-266
    • Christensen, E.I.1    Birn, H.2
  • 15
    • 0031720661 scopus 로고    scopus 로고
    • All four putative ligand-binding domains in megalin contain pathogenic epitopes capable of inducing passive Heymann nephritis
    • Yamazaki H, Ullrich R, Exner M, Saito A, Orlando RA, Kerjaschki D, Farquhar MG: All four putative ligand-binding domains in megalin contain pathogenic epitopes capable of inducing passive Heymann nephritis. J Am Soc Nephrol 9: 1638-1644, 1998
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1638-1644
    • Yamazaki, H.1    Ullrich, R.2    Exner, M.3    Saito, A.4    Orlando, R.A.5    Kerjaschki, D.6    Farquhar, M.G.7
  • 16
    • 0033971370 scopus 로고    scopus 로고
    • A small N-terminal 60-kD fragment of gp600 (megalin), the major autoantigen of active Heymann nephritis, can induce a full-blown disease
    • Oleinikov AV, Feliz BJ, Makker SP: A small N-terminal 60-kD fragment of gp600 (megalin), the major autoantigen of active Heymann nephritis, can induce a full-blown disease. J Am Soc Nephrol 11: 57-64, 2000
    • (2000) J Am Soc Nephrol , vol.11 , pp. 57-64
    • Oleinikov, A.V.1    Feliz, B.J.2    Makker, S.P.3
  • 17
    • 0028324029 scopus 로고
    • Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP)
    • Zheng G, Bachinsky DR, Stamenkovic I, Strickland DK, Brown D, Andres G, McCluskey RT: Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP). J Histochem Cytochem 42: 531-542, 1994
    • (1994) J Histochem Cytochem , vol.42 , pp. 531-542
    • Zheng, G.1    Bachinsky, D.R.2    Stamenkovic, I.3    Strickland, D.K.4    Brown, D.5    Andres, G.6    McCluskey, R.T.7
  • 18
    • 0032837162 scopus 로고    scopus 로고
    • Megalin in normal tissues and carcinoma cells carries oligo/poly alpha2,8 deaminoneuraminic acid as a unique posttranslational modification
    • Ziak M, Meier M, Roth J: Megalin in normal tissues and carcinoma cells carries oligo/poly alpha2,8 deaminoneuraminic acid as a unique posttranslational modification. Glycoconj J 16: 185-188, 1999
    • (1999) Glycoconj J , vol.16 , pp. 185-188
    • Ziak, M.1    Meier, M.2    Roth, J.3
  • 19
    • 0032956457 scopus 로고    scopus 로고
    • Identification of megalin as the sole rat kidney sialoglycoprotein containing poly alpha2,8 deaminoneuraminic acid
    • Ziak M, Kerjaschki D, Farquhar MG, Roth J: Identification of megalin as the sole rat kidney sialoglycoprotein containing poly alpha2,8 deaminoneuraminic acid. J Am Soc Nephrol 10: 203-209, 1999
    • (1999) J Am Soc Nephrol , vol.10 , pp. 203-209
    • Ziak, M.1    Kerjaschki, D.2    Farquhar, M.G.3    Roth, J.4
  • 20
    • 0024206422 scopus 로고
    • A possible ligand of serum origin for the kidney autoantigen of Heymann nephritis
    • Kanalas JJ, Makker SP: A possible ligand of serum origin for the kidney autoantigen of Heymann nephritis. J Immunol 141: 4152-4157, 1988
    • (1988) J Immunol , vol.141 , pp. 4152-4157
    • Kanalas, J.J.1    Makker, S.P.2
  • 21
    • 0027494324 scopus 로고
    • Analysis of glomeruli-eluted Gp330 autoantibodies and of Gp330 antigen of Heymann nephritis
    • Makker SP: Analysis of glomeruli-eluted Gp330 autoantibodies and of Gp330 antigen of Heymann nephritis. J Immunol 151: 6500-6508, 1993
    • (1993) J Immunol , vol.151 , pp. 6500-6508
    • Makker, S.P.1
  • 22
    • 0029069289 scopus 로고
    • Transcription and translation of gp600 and receptor-associated protein (RAP) in active Heymann nephritis
    • Makker S, Widstrom R, Huang J: Transcription and translation of gp600 and receptor-associated protein (RAP) in active Heymann nephritis. Am J Pathol 146: 1481-1487, 1995
    • (1995) Am J Pathol , vol.146 , pp. 1481-1487
    • Makker, S.1    Widstrom, R.2    Huang, J.3
  • 23
    • 0018148111 scopus 로고
    • Classes and subclasses of rat immunoglobulins: Interaction with the complement system and with staphylococcal protein A
    • Medgyesi GA, Fust G, Gergely J, Bazin H: Classes and subclasses of rat immunoglobulins: Interaction with the complement system and with staphylococcal protein A. Mol Immunol 15: 125-129, 1978
    • (1978) Mol Immunol , vol.15 , pp. 125-129
    • Medgyesi, G.A.1    Fust, G.2    Gergely, J.3    Bazin, H.4
  • 26
    • 0022551108 scopus 로고
    • Complement-induced glomerular epithelial cell injury. Role of the membrane attack complex in rat membranous nephropathy
    • Cybulsky AV, Rennke HG, Feintzeig ID, Salant DJ: Complement-induced glomerular epithelial cell injury. Role of the membrane attack complex in rat membranous nephropathy. J Clin Invest 77: 1096-1107, 1986
    • (1986) J Clin Invest , vol.77 , pp. 1096-1107
    • Cybulsky, A.V.1    Rennke, H.G.2    Feintzeig, I.D.3    Salant, D.J.4
  • 27
    • 0024598866 scopus 로고
    • Heymann nephritis: Mechanisms of renal injury
    • Salant DJ, Quigg RJ, Cybulsky AV: Heymann nephritis: Mechanisms of renal injury. Kidney Int 35: 976-984, 1989
    • (1989) Kidney Int , vol.35 , pp. 976-984
    • Salant, D.J.1    Quigg, R.J.2    Cybulsky, A.V.3
  • 28
    • 0032487498 scopus 로고    scopus 로고
    • Inhibition of complement regulation is key to the pathogenesis of active Heymann nephritis
    • Schiller B, He C, Salant DJ, Lim A, Alexander JJ, Quigg RJ: Inhibition of complement regulation is key to the pathogenesis of active Heymann nephritis. J Exp Med 188: 1353-1358, 1998
    • (1998) J Exp Med , vol.188 , pp. 1353-1358
    • Schiller, B.1    He, C.2    Salant, D.J.3    Lim, A.4    Alexander, J.J.5    Quigg, R.J.6
  • 31
    • 0032588777 scopus 로고    scopus 로고
    • Expression of oligo/polyalpha2,8-linked deaminoneuraminic acid and megalin during kidney development and maturation: Mutually exclusive distribution with polyalpha2,8-linked N-acetylneuraminic acid of N-CAM
    • Ziak M, Roth J: Expression of oligo/polyalpha2,8-linked deaminoneuraminic acid and megalin during kidney development and maturation: Mutually exclusive distribution with polyalpha2,8-linked N-acetylneuraminic acid of N-CAM. Histochem Cell Biol 112: 169-178, 1999
    • (1999) Histochem Cell Biol , vol.112 , pp. 169-178
    • Ziak, M.1    Roth, J.2
  • 32
    • 0034058722 scopus 로고    scopus 로고
    • Characterization of the N-linked oligosaccharides of megalin (gp330) from rat kidney
    • Morelle W, Haslam SM, Ziak M, Roth J, Morris HR, Dell A: Characterization of the N-linked oligosaccharides of megalin (gp330) from rat kidney. Glycobiology 10: 295-304, 2000
    • (2000) Glycobiology , vol.10 , pp. 295-304
    • Morelle, W.1    Haslam, S.M.2    Ziak, M.3    Roth, J.4    Morris, H.R.5    Dell, A.6
  • 34
    • 0035424309 scopus 로고    scopus 로고
    • Post-translational protein modifications in antigen recognition and autoimmunity
    • Doyle HA, Mamula MJ: Post-translational protein modifications in antigen recognition and autoimmunity. Trends Immunol 22: 443-449, 2001
    • (2001) Trends Immunol , vol.22 , pp. 443-449
    • Doyle, H.A.1    Mamula, M.J.2
  • 35
    • 0036231529 scopus 로고    scopus 로고
    • Posttranslational protein modifications: New flavors in the menu of autoantigens
    • Doyle HA, Mamula MJ: Posttranslational protein modifications: New flavors in the menu of autoantigens. Curr Opin Rheumatol 14: 244-249, 2002
    • (2002) Curr Opin Rheumatol , vol.14 , pp. 244-249
    • Doyle, H.A.1    Mamula, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.