메뉴 건너뛰기




Volumn 188, Issue 7, 1998, Pages 1353-1358

Inhibition of complement regulation is key to the pathogenesis of active Heymann nephritis

Author keywords

Autoantibodies; Complement regulation; Crry; Glomerulus; Heymann nephritis

Indexed keywords

AUTOANTIBODY; COMPLEMENT COMPONENT C3; IMMUNOGLOBULIN G;

EID: 0032487498     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.7.1353     Document Type: Article
Times cited : (53)

References (42)
  • 1
    • 0024212032 scopus 로고
    • Experimental glomerulonephritis
    • Salant, D.J., and A.V. Cybulsky. 1988. Experimental glomerulonephritis. Methods Enzymol. 162:421-461.
    • (1988) Methods Enzymol. , vol.162 , pp. 421-461
    • Salant, D.J.1    Cybulsky, A.V.2
  • 2
    • 0030410436 scopus 로고    scopus 로고
    • Molecular mechanisms of glomerular injury in rat experimental membranous nephropathy (Heymann nephritis)
    • Kerjaschki, D., and T.J. Neale. 1996. Molecular mechanisms of glomerular injury in rat experimental membranous nephropathy (Heymann nephritis). J. Am. Soc. Nephrol. 7:2518-2526.
    • (1996) J. Am. Soc. Nephrol. , vol.7 , pp. 2518-2526
    • Kerjaschki, D.1    Neale, T.J.2
  • 3
    • 0019210858 scopus 로고
    • A new role for complement in experimental membranous nephropathy in rats
    • Salant, D.J., S. Belok, M.P. Madaio, and W.G. Couser. 1980. A new role for complement in experimental membranous nephropathy in rats. J. Clin. Invest. 66:1339-1350.
    • (1980) J. Clin. Invest. , vol.66 , pp. 1339-1350
    • Salant, D.J.1    Belok, S.2    Madaio, M.P.3    Couser, W.G.4
  • 4
    • 0027494324 scopus 로고
    • Analysis of glomeruli-eluted Gp330 autoantibodies and of Gp330 antigen of Heymann nephritis
    • Makker, S.P. 1993. Analysis of glomeruli-eluted Gp330 autoantibodies and of Gp330 antigen of Heymann nephritis. J. Immunol. 151:6500-6508.
    • (1993) J. Immunol. , vol.151 , pp. 6500-6508
    • Makker, S.P.1
  • 5
    • 0022551108 scopus 로고
    • Complement-induced glomerular epithelial cell injury: Role of the membrane attack complex in rat membranous nephropathy
    • Cybulsky, A.V., H.G. Rennke, I.D. Feintzeig, and D.J. Salant. 1986. Complement-induced glomerular epithelial cell injury: role of the membrane attack complex in rat membranous nephropathy. J. Clin. Invest. 77:1096-1107.
    • (1986) J. Clin. Invest. , vol.77 , pp. 1096-1107
    • Cybulsky, A.V.1    Rennke, H.G.2    Feintzeig, I.D.3    Salant, D.J.4
  • 6
    • 0023713899 scopus 로고
    • Anti-Fx1A produces complement-dependent cytotoxicity of glomerular epithelial cells
    • Quigg, R.J., A.V. Cybulsky, J.B. Jacobs, and D.J. Salant. 1988. Anti-Fx1A produces complement-dependent cytotoxicity of glomerular epithelial cells. Kidney Int. 34:43-52.
    • (1988) Kidney Int. , vol.34 , pp. 43-52
    • Quigg, R.J.1    Cybulsky, A.V.2    Jacobs, J.B.3    Salant, D.J.4
  • 7
    • 0024464371 scopus 로고
    • Depletion of C6 prevents development of proteinuria in experimental membranous nephropathy in rats
    • Baker, P.J., R.F. Ochi, M. Schulze, R.J. Johnson, C. Campbell, and W.G. Couser. 1989. Depletion of C6 prevents development of proteinuria in experimental membranous nephropathy in rats. Am. J. Pathol. 135:185-194.
    • (1989) Am. J. Pathol. , vol.135 , pp. 185-194
    • Baker, P.J.1    Ochi, R.F.2    Schulze, M.3    Johnson, R.J.4    Campbell, C.5    Couser, W.G.6
  • 8
    • 0004846480 scopus 로고
    • The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border
    • Kerjaschki, D., and M.G. Farquhar. 1982. The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border. Proc. Natl. Acad. Sci. USA 79:5557-5581.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 5557-5581
    • Kerjaschki, D.1    Farquhar, M.G.2
  • 9
    • 0025216074 scopus 로고
    • Molecular cloning of a cDNa encoding a major pathogenic domain of the Heymann nephritis antigen gp330
    • Pietromonaco, S., D. Kerjaschki, S. Binder, R. Ullrich, and M.G. Farquhar. 1990. Molecular cloning of a cDNA encoding a major pathogenic domain of the Heymann nephritis antigen gp330. Proc. Natl. Acad. Sci. USA. 87:1811-1815.
    • (1990) Proc. Natl. Acad. Sci. USA. , vol.87 , pp. 1811-1815
    • Pietromonaco, S.1    Kerjaschki, D.2    Binder, S.3    Ullrich, R.4    Farquhar, M.G.5
  • 11
    • 0029965469 scopus 로고    scopus 로고
    • Induction of Heymann nephritis with a gp330/megalin fusion protein
    • Raychowdhury, R., G. Zheng, D. Brown, and R.T. McCluskey. 1996. Induction of Heymann nephritis with a gp330/megalin fusion protein. Am. J. Pathol. 148:1613-1623.
    • (1996) Am. J. Pathol. , vol.148 , pp. 1613-1623
    • Raychowdhury, R.1    Zheng, G.2    Brown, D.3    McCluskey, R.T.4
  • 12
    • 0021799978 scopus 로고
    • P65: A C3b-binding protein on murine cells that shares antigenic determinants with the human C3b receptor (CR1) and is distinct from murine C3b receptor
    • Wong, W., and D.T. Fearon. 1985. p65: a C3b-binding protein on murine cells that shares antigenic determinants with the human C3b receptor (CR1) and is distinct from murine C3b receptor. J. Immunol. 134:4048-4056.
    • (1985) J. Immunol. , vol.134 , pp. 4048-4056
    • Wong, W.1    Fearon, D.T.2
  • 13
    • 0024534350 scopus 로고
    • The murine complement receptor gene family. I. Analysis of mCRY gene products and their homology to human CR1
    • Paul, M.S., M. Aegerter, S.E. O'Brien, C.B. Kurtz, and J.H. Weis. 1989. The murine complement receptor gene family. I. Analysis of mCRY gene products and their homology to human CR1. J. Immunol. 142:582-589.
    • (1989) J. Immunol. , vol.142 , pp. 582-589
    • Paul, M.S.1    Aegerter, M.2    O'Brien, S.E.3    Kurtz, C.B.4    Weis, J.H.5
  • 14
    • 0027313975 scopus 로고
    • Mouse Crry/p65 is a regulator of the alternative pathway of complement activation
    • Foley, S., B. Li, M. Dehoff, H. Molina, and V.M. Holers. 1993. Mouse Crry/p65 is a regulator of the alternative pathway of complement activation. Eur. J. Immunol. 23:1381-1384.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1381-1384
    • Foley, S.1    Li, B.2    Dehoff, M.3    Molina, H.4    Holers, V.M.5
  • 15
    • 0027442105 scopus 로고
    • Mouse Crry/p65: Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF
    • Li, B., C. Sallee, M. Dehoff, S. Foley, H. Molina, and V.M. Holers. 1993. Mouse Crry/p65: Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF. J. Immunol. 151:4295-4305.
    • (1993) J. Immunol. , vol.151 , pp. 4295-4305
    • Li, B.1    Sallee, C.2    Dehoff, M.3    Foley, S.4    Molina, H.5    Holers, V.M.6
  • 16
    • 0028954469 scopus 로고
    • Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein
    • Kim, Y.-U., T. Kinoshita, H. Molina, D. Hourcade, T. Seya, L.M. Wagner, and V.M. Holers. 1995. Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein. J. Exp. Med. 181:151-159.
    • (1995) J. Exp. Med. , vol.181 , pp. 151-159
    • Kim, Y.-U.1    Kinoshita, T.2    Molina, H.3    Hourcade, D.4    Seya, T.5    Wagner, L.M.6    Holers, V.M.7
  • 17
    • 0029084359 scopus 로고
    • Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells
    • Quigg, R.J., B.P. Morgan, V.M. Holers, S. Adler, A.E. Sneed, and C.F. Lo. 1995. Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells. Kidney Int. 48:412-421.
    • (1995) Kidney Int. , vol.48 , pp. 412-421
    • Quigg, R.J.1    Morgan, B.P.2    Holers, V.M.3    Adler, S.4    Sneed, A.E.5    Lo, C.F.6
  • 20
    • 0025824579 scopus 로고
    • Effect of nephritogenic antibody on complement regulation in cultured rat glomerular epithelial cells
    • Quigg, R.J., A.V. Cybulsky, and D.J. Salant. 1991. Effect of nephritogenic antibody on complement regulation in cultured rat glomerular epithelial cells. J. Immunol. 147:838-845.
    • (1991) J. Immunol. , vol.147 , pp. 838-845
    • Quigg, R.J.1    Cybulsky, A.V.2    Salant, D.J.3
  • 21
    • 0028946568 scopus 로고
    • Crry and CD59 regulate complement in rat glomerular epithelial cells and are inhibited by the nephritogenic antibody of passive Heymann nephritis
    • Quigg, R.J., V.M. Holers, B.P. Morgan, and A.E. Sneed. 1995. Crry and CD59 regulate complement in rat glomerular epithelial cells and are inhibited by the nephritogenic antibody of passive Heymann nephritis. J. Immunol. 154:3437-3443.
    • (1995) J. Immunol. , vol.154 , pp. 3437-3443
    • Quigg, R.J.1    Holers, V.M.2    Morgan, B.P.3    Sneed, A.E.4
  • 23
    • 0029162211 scopus 로고
    • Molecular characterization of rat Crry: Widespread distribution of two alternative forms of Crry mRNA
    • Quigg, R.J., C.F. Lo, J.J. Alexander, A.E. Sneed, and G. Moxley. 1995. Molecular characterization of rat Crry: widespread distribution of two alternative forms of Crry mRNA. Immunogenetics. 42:362-367.
    • (1995) Immunogenetics , vol.42 , pp. 362-367
    • Quigg, R.J.1    Lo, C.F.2    Alexander, J.J.3    Sneed, A.E.4    Moxley, G.5
  • 24
    • 0031570281 scopus 로고    scopus 로고
    • Production of the rat complement regulator, Crry, as an active soluble protein in Pichia pastoris
    • He, C., J.J. Alexander, A. Lim, and R.J. Quigg. 1997. Production of the rat complement regulator, Crry, as an active soluble protein in Pichia pastoris. Arch. Biochem. Biophys. 341: 347-352.
    • (1997) Arch. Biochem. Biophys. , vol.341 , pp. 347-352
    • He, C.1    Alexander, J.J.2    Lim, A.3    Quigg, R.J.4
  • 25
    • 0024227144 scopus 로고
    • Type II collagen-induced arthritis in rats
    • Ridge, S.C., A.L. Oronsky, and S.S. Kerwar. 1988. Type II collagen-induced arthritis in rats. Methods Enzymol. 162: 355-360.
    • (1988) Methods Enzymol. , vol.162 , pp. 355-360
    • Ridge, S.C.1    Oronsky, A.L.2    Kerwar, S.S.3
  • 26
    • 0024393715 scopus 로고
    • Studies with antibodies to cultured rat glomerular epithelial cells: Subepithehal immune deposit formation after in vivo injection
    • Quigg, R.J., D.R. Abrahamson, A.V. Cybulsky, J. Badalamenti, A.W.M. Minto, and D.J. Salant. 1989. Studies with antibodies to cultured rat glomerular epithelial cells: subepithehal immune deposit formation after in vivo injection. Am. J. Pathol. 134:1125-1133.
    • (1989) Am. J. Pathol. , vol.134 , pp. 1125-1133
    • Quigg, R.J.1    Abrahamson, D.R.2    Cybulsky, A.V.3    Badalamenti, J.4    Minto, A.W.M.5    Salant, D.J.6
  • 28
    • 0028329185 scopus 로고
    • Complement inhibitor of rat cell membrane resembling mouse Crry/p65
    • Takizawa, H., N. Okada, and H. Okada. 1994. Complement inhibitor of rat cell membrane resembling mouse Crry/p65. J. Immunol. 152:3032-3038.
    • (1994) J. Immunol. , vol.152 , pp. 3032-3038
    • Takizawa, H.1    Okada, N.2    Okada, H.3
  • 29
    • 0026647670 scopus 로고
    • 1-integrin on glomerular epithelial cells and inhibits adhesion and growth
    • 1-integrin on glomerular epithelial cells and inhibits adhesion and growth. Am. J. Physiol. 262:F770-F776.
    • (1992) Am. J. Physiol. , vol.262
    • Adler, S.1    Chen, X.2
  • 30
    • 0028334224 scopus 로고
    • Antibodies to glycolipids activate complement and promote proteinuria in passive Heymann nephritis
    • Susani, M., M. Schulze, M. Exner, and D. Kerjaschki. 1994. Antibodies to glycolipids activate complement and promote proteinuria in passive Heymann nephritis. Am. J. Pathol. 144: 807-819.
    • (1994) Am. J. Pathol. , vol.144 , pp. 807-819
    • Susani, M.1    Schulze, M.2    Exner, M.3    Kerjaschki, D.4
  • 31
    • 0000098775 scopus 로고    scopus 로고
    • Glomerular injury due to antibody alone
    • E.G. Neilson and W.G. Couser, editors. Lippincott-Raven, Philadelphia
    • Salant, D.J., Y. Natori, and F. Shimizu. 1997. Glomerular injury due to antibody alone. In Immunologic Renal Diseases. E.G. Neilson and W.G. Couser, editors. Lippincott-Raven, Philadelphia. 359-375.
    • (1997) Immunologic Renal Diseases , pp. 359-375
    • Salant, D.J.1    Natori, Y.2    Shimizu, F.3
  • 32
    • 0024475110 scopus 로고
    • Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor
    • Raychowdhury, R., J.L. Niles, R.T. McCluskey, and J.A. Smith. 1989. Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor. Science. 244:1163-1165.
    • (1989) Science. , vol.244 , pp. 1163-1165
    • Raychowdhury, R.1    Niles, J.L.2    McCluskey, R.T.3    Smith, J.A.4
  • 33
    • 0024566684 scopus 로고
    • Decay accelerating factor regulates complement activation on glomerular epithelial cells
    • Quigg, R.J., A. Nicholson-Weller, A.V. Cybulsky, J. Badalamenti, and D.J. Salant. 1989. Decay accelerating factor regulates complement activation on glomerular epithelial cells. J. Immunol. 142:877-882.
    • (1989) J. Immunol. , vol.142 , pp. 877-882
    • Quigg, R.J.1    Nicholson-Weller, A.2    Cybulsky, A.V.3    Badalamenti, J.4    Salant, D.J.5
  • 37
    • 0029011719 scopus 로고
    • Urinary excretion of protectin (CD59), complement SC5b-9 and cytokines in membranous glomerulonephritis
    • Lehto, T., E. Honkanen, A.M. Teppo, and S. Meri. 1995. Urinary excretion of protectin (CD59), complement SC5b-9 and cytokines in membranous glomerulonephritis. Kidney Int. 47:1403-1411.
    • (1995) Kidney Int. , vol.47 , pp. 1403-1411
    • Lehto, T.1    Honkanen, E.2    Teppo, A.M.3    Meri, S.4
  • 39
    • 0028120820 scopus 로고
    • Therapeutic uses of recombinant complement protein inhibitors
    • Kalli, K.R., P. Hsu, and D.T. Fearon. 1994. Therapeutic uses of recombinant complement protein inhibitors. Springer Semin. Immunopathol. 15:417-431.
    • (1994) Springer Semin. Immunopathol. , vol.15 , pp. 417-431
    • Kalli, K.R.1    Hsu, P.2    Fearon, D.T.3
  • 40
    • 0028085598 scopus 로고
    • Therapeutic regulation of the complement system in acute injury states
    • Moore, F.D., Jr. 1994. Therapeutic regulation of the complement system in acute injury states. Adv. Immunol. 56:267-299.
    • (1994) Adv. Immunol. , vol.56 , pp. 267-299
    • Moore Jr., F.D.1
  • 41
    • 0029031562 scopus 로고
    • The effects of soluble recombinant complement receptor 1 on complement-mediated experimental glomerulonephritis
    • Couser, W.G., R.J. Johnson, B.A. Young, C.G. Yeh, C.A. Toth, and A.R. Rudolph. 1995. The effects of soluble recombinant complement receptor 1 on complement-mediated experimental glomerulonephritis. J. Am. Soc. Nephrol. 5: 1888-1894.
    • (1995) J. Am. Soc. Nephrol. , vol.5 , pp. 1888-1894
    • Couser, W.G.1    Johnson, R.J.2    Young, B.A.3    Yeh, C.G.4    Toth, C.A.5    Rudolph, A.R.6
  • 42
    • 0031569285 scopus 로고    scopus 로고
    • A soluble chimeric complement inhibitory protein that possesses both decay-accelerating and factor I cofactor activities
    • Higgins, P.J., K. Jone-Long, R. Lobell, C. Sardonini, M.K. Alessi, and C.G. Yeh. 1997. A soluble chimeric complement inhibitory protein that possesses both decay-accelerating and factor I cofactor activities. J. Immunol. 158:2872-2881.
    • (1997) J. Immunol. , vol.158 , pp. 2872-2881
    • Higgins, P.J.1    Jone-Long, K.2    Lobell, R.3    Sardonini, C.4    Alessi, M.K.5    Yeh, C.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.