Characterization of the N-linked oligosaccharides of megalin (gp330) from rat kidney

Glycobiology

Volumn 10, Issue 3, 2000, Pages 295-304

  Morelle, Willy ^a   Haslam, Stuart M ^a   Ziak, Martin ^b   Roth, Jürgen ^b   Morris, Howard R ^a   Dell, Anne ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

gp330; Mass spectrometry; Megalin; N glycans; Structure analysis

Indexed keywords

CELL SURFACE RECEPTOR; GLYCAN; MANNOSE; MEGALIN; OLIGOSACCHARIDE;

ANIMAL TISSUE; ARTICLE; CHEMICAL STRUCTURE; FUCOSYLATION; KIDNEY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; RAT;

ANIMALIA;

EID: 0034058722     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/10.3.295     Document Type: Article

References (46)

1. Albersheim, P., Nevins, D.J., English, P.D. and Karr, A. (1967) A method for the analysis of sugars in plant cell wall polysaccharides by gas-liquid chromatography. Carbohydr. Res., 5, 340-345.
2. Bachinsky, D., Zheng, G., Niles, J., McLaughlin, M., Abbate, M. andres, G., Brown, D. and McCluskey, R. (1993) Detection of two forms of Gp330. Their role in Heymann nephritis. Am. J. Pathol., 143, 598-611.
3. Baenziger, J.U. and Green, E.D. (1988) Pituitary glycoprotein hormone oligosaccharides - structure, synthesis and function of the asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin. Biochim. Biophys. Acta, 947, 287-306.
4. Blanchard, D., Cartron, J.-P., Fournet, B., Montreuil, J., Van Halbeck, H. and Vliegenthart, J.F.G. (1983) Primary structure of the oligosaccharide determinant of blood-group CAD specificity. J. Biol. Chem., 258, 7691-7695.
5. Blanken, W.M. and Van den Eijnden, D.H. (1985) Biosynthesis of terminal Galα1-3Galβ1-4GlcNAc-R oligosaccharide sequences on glycoconjugates. Purification and acceptor specificity of a UDP-Gal:N-acetyllactosaminide α1-3 galactosyltransferase from calf thymus. J. Biol. Chem., 260, 12927-12934.
6. a activity. Biochem. Biophys. Res. Commun., 106, 331-337.
7. Chatelet, F., Brianti, E., Ronco, P., Roland, J. and Verroust, P. (1986) Ultrastructural-localization by monoclonal-antibodies of brush border antigens expressed by glomeruli. 2. Extrarenal distribution. Am. J. Pathol., 122, 512-519.
8. Christensen, E., Nielsen, S., Moestrup, S., Borre, C., Maunsbach, A., Deheer, E., Ronco, P., Hammond, T. and Verroust, P. (1995) Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules. Eur. J. Cell Biol., 66, 349-364.
9. Coddeville, B., Strecker, G., Wieruszeski, J.-M., Vliegenthart, J.F.G., Van Halbeek, H., Peter-Katalinic, J., Egge, H. and Spik, G. (1992) Heterogeneity of bovine lactotransferrin glycans. Characterization of α-D-Galp (1-3)-β-D-Gal- and α-NeuAc- (2-6)-β-D-GalpNAc- (1-4)-β-D-GlcNAc-substituted N-linked glycans. Carbohydr. Res., 236, 145-164.
10. Conzelmann, A. and Kornfeld, S. (1984) β-linked N-acetylgalactosamine residues present at the nonreducing termini of O-linked oligosaccharides of a cloned murine cytotoxic T lymphocyte line are absent in a Vicia villosa lectin resistant mutant cell line. J. Biol. Chem., 259, 12528-12535.
11. Debray, H., Dus, D., Wieruszeski, J.-M., Strecker, G. and Montreuil, J. (1991) Structures of the α (1-3)-galactose-containing asparagine-linked glycans of a Lewis lung-carcinoma cell subline resistant to aleuria-aurantia agglutinin - elucidation by H-1-NMR spectroscopy. Glycoconjugate J., 8, 29-37.
12. Dell, A. and Khoo, K.-H. (1993) Covalent structure determination of glycopolymers. Curr. Opin. Struc. Biol., 3, 687-693.
13. Dell, A., Reason, A.J., Khoo, K.-H., Panico, M., Mc Dowell, R.A. and Morris, H.R. (1994) Mass spectrometry of carbohydrate-containing bipolymers. Methods Enzymol., 230, 108-132.
14. Dell, A., Morris, H.R., Easton, R.L., Panico, M., Patankar, M., Oehninger, S., Koistinen, R., Koistinen, H., Seppala, M. and Clark, G.F. (1995) Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities. J. Biol. Chem., 270, 24116-24126.
15. Galili, U., Clark, M.R., Shohet, S.B., Buehler, J. and Macher, B.A. (1987) Evolutionary relationship between the natural anti-Gal antibody and the Galα1-3Gal epitope in primates. Proc. Natl. Acad. Sci. USA, 84, 1369-1373.
16. Geyer, R., Geyer, H., Stirm, S., Hunsmann, G., Schneider, J., Dabrowski, U. and Dabrowski, J. (1984) Major oligosaccharides in the glycoprotein of friend murine leukemia-virus. Structure elucidation in the glycoprotein by one-dimensional and two-dimensional proton nuclear magnetic-resonance and methylation analysis. Biochemistry, 23, 5628-5637.
17. Guhl, B., Ziak, M. and Roth, J. (1998) Unconventional antigen retrieval for carbohydrate and protein antigens. Histochem. Cell Biol., 110, 603-611.
18. Hammond, T.G., Majewski, R.R., Kaysen, J.H., Goda, F.O., Navar, G.L., Pontillon, F. and Verroust, P.J. (1997) Gentamicin inhibits rat renal cortical homotypic endosomal fusion: role of megalin. Am. J. Physiol.-Renal Physiol., 41, F117-F123.
19. Hard, K., Van Zadelhoff, G., Moonen, P., Kamerling, J.P. and Vliegenthart, J.F.G. (1992) The Asn-linked carbohydrates chains of human Tamm-Horsfall glycoprotein of one male. Novel sulfated and novel N-acetylgalactosamine-containing N-linked carbohydrates chains. Em. J. Biochem., 209, 895-915.
20. Kanalas, J.J. and Makker, S.P. (1991) Identification of the rat heymann nephritis autoantigen (gp 330) as a receptor-site tor plasminogen. J. Biol. Chem., 266, 10825-10829.
21. Kerjaschki, D. and Farquhar, M.G. (1982) The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush-border. Proc. Natl. Acad. Sci. USA, 79, 5557-5561.
22. Kerjaschki, D. and Farquhar, M.G. (1983) Immunocytochemical localization of the Heymannn nephritis antigen (gp 330) in glomerular epithelial-cells of normal lewis rats. J. Exp. Med., 157, 667-686.
23. Kerjaschki, D., Miettinen, A. and Farquhar, M.G. (1987) Initial events in the formation of immune deposits in passive Heymann nephritis - gp330-anti-gp330 immune-complexes form in epithelial coated pits and rapidly become attached to the glomerular-basement-membrane. J. Exp. Med., 166, 109-128.
24. Kounnas, M.Z., Chappell, D.A., Strickland, D.K. and Argraves, W.S. (1993) Glycoprotein-330, a member of the low-density-lipoprotein receptor family, binds lipoprotein-lipase in vitro. J. Biol. Chem., 268, 14176-14181.
25. Lundgren, S., Hjalm, G., Hellman, P., Ek, B., Juhlin, C., Rastad, J., Klareskog, L., Akerstom, G. and Rask, L. (1994) A protein involved in calcium sensing of the human parathyroid and placental cytotrophoblast cells belongs to the LDL-receptor protein superfamily. Exp. Cell Res., 212, 344-350.
26. Moestrup, S.K., Birn, H., Fischer, P.B., Petersen, C.M., Verroust, P.J., Sim, R.B., Christensen, E.I. and Nexo, E. (1996) Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis. Proc. Natl. Acad. Sci. USA, 93, 8612-8617.
27. Moestrup, S.K., Cui, S., Vorum, H., Bregengård, C., Bjorn, S.E., Norris, K., Gliemann, J. and Christensen, E.I. (1995) Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs. J. Clin. Invest., 96, 1404-1413.
28. Nykjaer, A., Dragun, D., Walther, D., Vorum, H., Jacobsen, C., Herz, J., Melsen, F., Christensen, E.I. and Willnow, T.E. (1999) An endocytic pathway essential for renal uptake and activation of the steroid 25- (OH) vitamin D-3. Cell, 96, 507-515.
29. Orlando, R.A., Rader, K., Authier, F., Yamazaki, H., Posner, B.I., Bergeron, J.J.M. and Farquhar, M.G. (1998) Megalin is an endocytic receptor for insulin. J. Am. Soc. Nephrol., 9, 1759-1766.
30. Piller, F., Blanchard, D., Huet, M. and Cartron, J.-P. (1986) Identification of a α-NeuAc (2-3 )β-D-galactopyranosyl N-acetyl-β-D-galactosaminyltransferase in human kidney. Carbohydr. Res. 149, 171-184.
31. Saito, A., Pietromonaco, S., Loo, A.K. and Farquhar, M.G. (1994) Complete cloning and sequencing of rat gp330/"megalin", a distinctive member of the low density lipoprotein receptor gene family. Proc. Natl. Acad. Sci. USA, 91, 9725-9729.
32. Serafini-Cessi, F. and Dall'Olio, F. (1983) Guinea-pig kidney β-N-acetylgalactosaminyltransferase towards Tamm-Horsfall glycoprotein. Requirement of sialic acid in the acceptor for transferase activity. Biochem. J., 215, 483-489.
33. Serafini-Cessi, F., Malagolini, N. and Dall'Olio, F. (1988) Characterization and partial purification of β-N-acetylgalactosaminyltransferase from urine of Sd (a+) individuals. Arch. Biochem. Biophys., 266, 573-582.
34. Spiro, R.G. and Bhoyroo, V.D. (1984) Occurence of α-D-galactosyl residues in the thyroglobulins from several species. Localization in the saccharide chains of the complex carbohydrate units. J. Biol. Chem., 259, 9858-9866.
35. Takeya, A., Hosomi, O. and Kogure, T. (1987) Identification and characterization of UDP-GalNAc-NeuAc-α-2-3-Gal-β1-4Glc (NAc)-β-1-4- (GalNAc to Gal)N-acetylgalactosaminyltransferase in human blood plasma. J. Biochem. (Tokyo), 101, 251-259.
36. Van den Eijnden, D.H., Neeleman, A.P., Van der Kanpp, W.P.W., Bakker, H., Agterberg, M. and Van Die, I. (1995) Novel glycosylation routes for glycoprotein. The LacdiNAc pathway. Biochem. Soc. Trans., 23, 175-179.
37. Varki, A. (1993) Biological roles of oligosaccharides: all the theories are correct. Glycobiology, 3, 97-130.
38. Watkins, W.M. (1980) In Harris, H. and Hirschhorn, K. (eds.). Advances in Human Genetics, Vol. 10. Plenum Press, New York, pp. 1-116, 379-385.
39. Willnow, T.E., Goldstein, J.L., Orth, K., Brown, M.S. and Herz, J. (1992) Low-density-lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance. J. Biol. Chem., 267, 26172-26180.
40. Yamashita, K., Hitoi, A., Matsuda, Y., Tsuji, A., Katunuma, N. and Kobata, A. (1983) Structural studies of the carbohydrate moieties of rat kidney γ-glutamyltranspeptidase. An extremely heterogeneous pattern enriched with nonreducing terminal N-acetylglucosamine residues. J. Biol. Chem., 258, 1098-1107.
41. Yamashita, K., Tachibana, Y., Matsuda, Y., Katunuma, N., Kochibe, N. and Kobata, A. (1988) Comparative studies of the sugar chains of aminopeptidase N and dipeptidylpeptidase IV purified from rat kidney brush-border membrane. Biochemistry, 27, 5565-5573.
42. Zheng, G., Bachinsky, D.R., Stamenkovic, I., Strickland, D.K., Brown, D. andres, G. and McCluskey, R.T. (1994) Organ distribution in rats of 2 members of the low-density-lipoprotein receptor gene family, gp 330 and lrp/α-2mr and the receptor-associated protein (RAP). J. Histochem. Cytochem., 42, 531-542.
43. Zheng, G., Marino, M., Zhao, J. and McCluskey, R.T. (1998) Megalin (gp330): a putative endocytic receptor for thyroglobulin (Tg). Endocrinology, 139, 1462-1465.
44. Ziak, M., Kerjaschki, D., Farquhar, M.G. and Roth, J. (1996) The single poly α 2.8 deaminoneuraminic acid bearing glycoprotein in rat kidney corresponds to megalin. Mol. Biol. Cell. 7, 3466.
45. Ziak, M., Kerjaschki, D., Farquhar, M.G. and Roth, J. (1999a) Identification of megalin as the sole rat kidney sialoglycoprotein containing poly α 2.8 deaminoneuraminic acid. J. Am. Soc. Nephrol., 10, 203-209.
46. Ziak, M., Meier, M. and Roth, J. (1999b) Megalin in normal tissues and carcinoma cells carries oligo/poly α2,8 deaminoneuraminic acid as a unique posttranslational modification. Glycoconj. J., 16, 185-188.