Seungma-galgeun-tang attenuates proinflammatory activities through the inhibition of NF-κB signal pathway in the BV-2 microglial cells

Journal of Ethnopharmacology

Volumn 107, Issue 1, 2006, Pages 59-66

  Lyu, Sun Ae ^a   Lee, Seung Yeon ^a   Lee, Song Jin ^a   Son, Sung Woo ^a   Kim, Mun Ok ^a   Kim, Gi Young ^b   Kim, Young Hee ^c   Yoon, Hwa Jung ^a   Kim, Hoon ^a   Park, Dong Il ^a   Ko, Woo Shin ^a  

^a Dong Eui University   (South Korea)

^b Jeju National University   (South Korea)

^c Pusan National University   (South Korea)

Author keywords

Cyclooxygenase 2; Cytokines; Inducible nitric oxide synthase; Inhibitor kappa B; Nitric oxide; Nuclear factor kappa B; Seungma galgeun tang

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROSTAGLANDIN E2; SEUNGMA GALGEUN TANG; SYNAPTOTAGMIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CELL VIABILITY; CONCENTRATION RESPONSE; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; INFLAMMATION; MICROGLIA; NONHUMAN; PROSTAGLANDIN SYNTHESIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CYCLOOXYGENASE 2; DINOPROSTONE; DNA PRIMERS; DOWN-REGULATION; HYDROLYSIS; INFLAMMATION; INFLAMMATION MEDIATORS; MICE; MICROGLIA; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RNA, MESSENGER;

EID: 33745824260     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.02.002     Document Type: Article

References (47)

1. Adams V., Nehrhoff B., Spate U., Linke A., Schulze P.C., Baur A., Gielen S., Hambrecht R., and Schuler G. Induction of iNOS expression in skeletal muscle by IL-1β and NF-κB activation: an in vitro and in vivo study. Cardiovascular Research 54 (2002) 95-104
2. Adler K.B., Fischer B.M., Wright D.T., Cohn L.A., and Becker S. Interactions between respiratory epithelial cells and cytokines: relationships to lung inflammation. Annals of the New York Academy of Sciences 725 (1994) 128-145
3. Akiyama H., Barger S., Barnum S., Bradt B., Bauer J., Cole G.M., Cooper N.R., Eikelenboom P., Emmerling M., Fiebich B.L., Finch C.E., Frautschy S., Griffin W.S., Hampel H., Hull M., Landreth G., Lue L., Mrak R., Mackenzie I.R., McGeer P.L., O'Banion M.K., Pachter J., Pasinetti G., Plata-Salaman C., Rogers J., Rydel R., Shen Y., Streit W., Strohmeyer R., Tooyoma I., Van Muiswinkel F.L., Veerhuis R., Walker D., Webster S., Wegrzyniak B., Wenk G., and Wyss-Coray T. Inflammation and Alzheimer's disease. Neurobiology of Aging 21 (2000) 383-421
4. Albazzaz M.K., Pal C., Berman P., and Shale D.J. Inflammatory markers of lower respiratory tract infection in elderly people. Age and Aging 23 (1994) 299-302
5. Baldwin A.S. The NF-κB and Iκ-B proteins: new discoveries and insights. Annual Review of Immunology 14 (1996) 649-683
6. Bauer M.K., Lieb K., Schulze-Osthoff K., Berger M., Gebicke-Haerter P.J., Bauer J., and Fiebich B.L. Expression and regulation of cyclooxygenase-2 in rat microglia. European Journal of Biochemistry 243 (1997) 726-731
7. Candelario-Jalil E., Gonzalez-Falcon A., Garcia-Cabrera M., Leon O.S., and Fiebich B.L. Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat. Brain Research 1007 (2004) 98-108
8. Chang H.K., Yang H.Y., Lee T.H., Shin M.C., Lee M.H., Shin M.S., Kim C.J., Kim O.J., Hong S.P., and Cho S. Armeniacae semen extract suppresses lipopolysaccharide-induced expressions of cyclooxygenase [correction of cycloosygenase]-2 and inducible nitric oxide synthase in mouse BV2 microglial cells. Biological and Pharmaceutical Bulletin 28 (2005) 449-454
9. Dai Y., But P.P., Chan Y.P., Matsuda H., and Kubo M. Anti-pruritic and anti-inflammatory effects of aqueous extract from Si-Wu-Tang. Biological and Pharmaceutical Bulletin 25 (2002) 1175-1178
10. Dinarello C.A. Interleukin-1. Cytokine and Growth Factor Reviews 8 (1997) 253-265
11. Dubois R.N., Abramson S.B., Crofford L., Gupta R.A., Simon L.S., van De Putte L.B., and Lipsky P.E. Cyclooxygenase in biology and disease. FASEB Journal 12 (1998) 1063-1073
12. Eigler A., Sinha B., Hartmann G., and Endres S. Taming TNF: strategies to restrain this proinflammatory cytokine. Immunology Today 18 (1997) 487-492
13. Fiebich B.L., Biber K., Lieb K., van Calker D., Berger M., Bauer J., and Gebicke-Haerter P.J. Cyclooxygenase-2 expression in rat microglia is induced by adenosine A2a-receptors. Glia 18 (1996) 152-160
14. Fiebich B.L., Mueksch B., Boehringer M., and Hull M. Interleukin-1beta induces cyclooxygenase-2 and prostaglandin E(2) synthesis in human neuroblastoma cells: involvement of p38 mitogen-activated protein kinase and nuclear factor-κB. Journal of Neurochemistry 75 (2000) 2020-2028
15. 2 release in primary rat microglia. Journal of Neurochemistry 86 (2003) 173-178
16. Funk C.D. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 294 (2001) 1871-1875
17. Ghosh S., May M.J., and Kopp E.B. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annual Review of Immunology 16 (1998) 225-260
18. Guzik T.J., Korbut R., and Adamek-Gusik T. Nitric oxide and superoxide in inflammation and immune regulation. Journal of Physiology and Pharmacology 55 (2003) 469-487
19. Harbrecht B.G., Di Silvio M., Demetris A.J., Simmons R.L., and Billiar T.R. Tumor necrosis factor-alpha regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia. Hepatology 20 (1994) 1055-1060
20. Heo, J., 1999. DongEuiBoGam. Bub, Seoul. p. 731,937, in press.
21. Karin M., and Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa] B activity. Annual Review of Immunology 18 (2000) 621-663
22. Karin M., and Delhase M. The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signaling. Seminars in Immunology 12 (2000) 85-98
23. Kim S.H., Lee S.E., Oh H., Kim S.R., Yee S.T., Yu Y.B., Byun M.W., and Jo S.K. The radioprotective effects of bu-zhong-yi-qi-tang: a prescription of traditional Chinese medicine. American Journal of Chinese Medicine 30 (2002) 127-137
24. Liaudet L., Soriano E.G., and Szabo C. Biology of nitric oxide signaling. Critical Care Medicine 28 (2000) 37-52
25. Lin Y.L., and Lin J.K. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Molecular Pharmacology 52 (1997) 465-472
26. Ma X., and Trinchieri G. Regulation of interleukin-12 production in antigen-presenting cells. Advances in Immunology 79 (2001) 55-92
27. Ma J., Cheng G., Li D., and Liu H. The effects of Radix Puerariae decoction on levels of antibody and interleukin-2 in mice. Zhong Yao Cai 25 (2002) 731-732
28. MacMicking J., Xie Q.W., and Nathan C. Nitric oxide and macrophage function. Annual Review of Immunology 15 (1997) 323-350
29. Marletta M.A., Yoon P.S., Iyengar R., Leaf C.D., and Wishnok J.S. Macrophage oxidation of l-arginine to nitrite and nitrate: nitrite oxide is an intermediate. Biochemistry 27 (1998) 8706-8711
30. Minghetti L., and Levi G. Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures. Journal of Neurochemistry 65 (1995) 2690-2698
31. Moncada S., Palmer R.M., and Higgs E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacological Reviews 43 (1991) 109-142
32. Muller J.M., Ziegler-Heitbrock H.W.L., and Baeuerle P.A. Nuclear factor kappa B, a mediator of lipopolysaccharide effects. Immunobiology 187 (1993) 233-256
33. Munoz-Fernandez M.A., Fernandez M.A., and Fresno M. Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. European Journal of Immunology 22 (1992) 301-307
34. Murata T., Ushikubi F., Matsuoka T., Hirata M., Yamasaki A., Sugimoto Y., Ichikawa A., Aze Y., Tanaka T., Yoshida N., Ueno A., Oh-ishi S., and Narumiya S. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature 388 (1997) 678-682
35. O'Banion M.K., Miller J.C., Chang J.W., Kaplan M.D., and Coleman P.D. Interleukin-1β induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures. Journal of Neurochemistry 66 (1996) 2532-2540
36. Perry V.H., and Gordon S. Macrophages and microglia in the nervous system. Trends in Neurosciences 11 (1998) 273-277
37. Raz A., Wyche A., Siegel N., and Needleman P. Regulation of fibroblast cyclooxygenase synthesis by interleukin-1. Journal of Biological Chemistry 263 (1998) 3022-3028
38. Rink L., and Kirchner H. Recent progress in the tumor necrosis factor-alpha fiele. International Archives of Allergy and Applied Immunology 111 (1996) 199-209
39. Schletter J., Heine H., Ulmer A.J., and Rietschel E.T. Molecular mechanisms of endotoxin activity. Archives in Microbiology 164 (1995) 383-389
40. Schmidt H.H.H.W., and Kelm M. Determination of nitrite and nitrate by the Griess reaction. Methods in Nitric Oxide Research (1996), John-Wiley and Sons Ltd. pp. 491-497
41. Shin M.K., An D.K., and Lee S.I. Clinical Application of Oriental Medicine (1982), Sungbosa, Seoul pp. 71
42. Skehan P. Assays of cell growth and cytotoxicity. In: Studzinski G.P. (Ed). Cell Growth and Apoptosis (1998), Oxford University press, New York 180
43. Smith W.L., DeWitt D.L., and Garavito R.M. Cyclooxygenases: structural, cellular, and molecular biology. Annual Review of Biochemistry 69 (2000) 145-182
44. Trinchieri G. Proinflammatory and immunoregulatory functions of interleukin-12. International Reviews of Immunology 16 (1998) 365-396
45. Xie Q.W., Whisnant R., and Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon g and bacterial lipopolysaccharide. Journal of Experimental Medicine 177 (1993) 1779-1784
46. Xie Q.W., Kashiwabara Y., and Nathan C. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. Journal of Biological Chemistry 269 (1994) 4705-4708
47. Yui Y., Hattori R., Kosuga K., Eizawa H., Hiki K., and Kawai C. Purification of nitric oxide synthase from rat macrophages. Journal of Biological Chemistry 266 (1991) 12544-12547