메뉴 건너뛰기




Volumn 190, Issue 1, 2006, Pages 55-73

Xenobiotic-metabolizing polymorphic enzymes. An opportunity for individualized drug treatment;Le polymorphisme génétique des enzymes du métabolisme des médicaments. Une opportunité pour un traitement individualisé

Author keywords

Cytochrome P450 enzym system; Methyltransferases; Pharmacogenetics

Indexed keywords


EID: 33745769055     PISSN: 00014079     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0001-4079(19)33353-9     Document Type: Review
Times cited : (3)

References (35)
  • 1
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
    • LAZAROU J., POMERANZ B., COREY P. - Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. J. Am. Med. Assoc., 1998, 279, 1200-5.
    • (1998) J. Am. Med. Assoc. , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.2    Corey, P.3
  • 2
    • 0009829065 scopus 로고    scopus 로고
    • Admissions to hospital caused by adverse drugs reactions: Cross sectional incidence study
    • POUYANNE P., HARAMBURU F., IMBS J., BEGAUD B. - Admissions to hospital caused by adverse drugs reactions: cross sectional incidence study. Br. Med. J., 2000, 320, 1036.
    • (2000) Br. Med. J. , vol.320 , pp. 1036
    • Pouyanne, P.1    Haramburu, F.2    Imbs, J.3    Begaud, B.4
  • 3
    • 0027399842 scopus 로고
    • Study of glucose-6-phosphate deshydrogenase: History and molecular biology
    • BEUTLER E. - Study of glucose-6-phosphate deshydrogenase: history and molecular biology. Am. J. Hematol., 1993, 42, 53-8.
    • (1993) Am. J. Hematol. , vol.42 , pp. 53-58
    • Beutler, E.1
  • 4
    • 26444539817 scopus 로고
    • Genetic control of isoniazid metabolism in man
    • EVANS DAP., MANLEY KA., MCKUSICK VA. - Genetic control of isoniazid metabolism in man. Br. Med. J., 1960, 2, 485-91.
    • (1960) Br. Med. J. , vol.2 , pp. 485-491
    • Evans, D.A.P.1    Manley, K.A.2    McKusick, V.A.3
  • 5
    • 0032793249 scopus 로고    scopus 로고
    • Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
    • INGELMANN-SUNDBERG M., OSCARSON M., MCLELLAN R. - Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment. TIPS, 1999, 20, 342-9.
    • (1999) TIPS , vol.20 , pp. 342-349
    • Ingelmann-Sundberg, M.1    Oscarson, M.2    McLellan, R.3
  • 6
    • 0037328994 scopus 로고    scopus 로고
    • Pharmacogenetics of the major polymorphic metabolising enzymes
    • DALY A. - Pharmacogenetics of the major polymorphic metabolising enzymes. Fundam. Clin. Pharmacol., 2003, 17, 27-41.
    • (2003) Fundam. Clin. Pharmacol. , vol.17 , pp. 27-41
    • Daly, A.1
  • 7
    • 0038294345 scopus 로고    scopus 로고
    • Pharmacogenetics of drug metabolising enzymes: Importance for personalised medecine
    • OSCARSON M. - Pharmacogenetics of drug metabolising enzymes: importance for personalised medecine. Clin. Chem. Lab. Med., 2003, 41, 573-80.
    • (2003) Clin. Chem. Lab. Med. , vol.41 , pp. 573-580
    • Oscarson, M.1
  • 8
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likehood of metabolic pharmacokinetic interactions
    • BERTZ RJ., GRAMMENAM GR. - Use of in vitro and in vivo data to estimate the likehood of metabolic pharmacokinetic interactions. Clin. Pharmacokinet., 1997, 32, 210-258.
    • (1997) Clin. Pharmacokinet. , vol.32 , pp. 210-258
    • Bertz, R.J.1    Grammenam, G.R.2
  • 9
    • 0026254621 scopus 로고
    • Genotype or phenotype: The definition of a pharmacogenetic polymorphism
    • MEYER U. - Genotype or phenotype: the definition of a pharmacogenetic polymorphism. Pharmacogenetics, 1991, 1, 66-7.
    • (1991) Pharmacogenetics , vol.1 , pp. 66-67
    • Meyer, U.1
  • 10
    • 0033973035 scopus 로고    scopus 로고
    • Interethnic differences of drug-metabolising enzymes
    • GAEDIGK A. - Interethnic differences of drug-metabolising enzymes. Int. J. Clin. Pharmacol. Ther., 2000, 38, 61-8.
    • (2000) Int. J. Clin. Pharmacol. Ther. , vol.38 , pp. 61-68
    • Gaedigk, A.1
  • 11
    • 4544292592 scopus 로고    scopus 로고
    • La pharmacogénétique ou la promesse d'une médecine personnalisée: Variations du métabolisme et du transport des médicaments
    • ALLORGE D., LORIOT MA. - La pharmacogénétique ou la promesse d'une médecine personnalisée: variations du métabolisme et du transport des médicaments. Ann. Biol. Clin., 2004, 62, 500-511.
    • (2004) Ann. Biol. Clin. , vol.62 , pp. 500-511
    • Allorge, D.1    Loriot, M.A.2
  • 12
    • 0742286803 scopus 로고    scopus 로고
    • Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
    • ZANGER U., RAIMUNDO S., EICHELBAUM M. - Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn-Schmiedeberg's Arch. Pharmacol., 2004, 369, 133-40.
    • (2004) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.369 , pp. 133-140
    • Zanger, U.1    Raimundo, S.2    Eichelbaum, M.3
  • 13
    • 0346363770 scopus 로고    scopus 로고
    • CYP2D6 genotyping strategy based on gene copy number determination by Taqman real-time PCR
    • SCHAEFFELER E., SCHWAB M., EICHELBAUM M., ZANGER U. - CYP2D6 genotyping strategy based on gene copy number determination by Taqman real-time PCR. Human Mutat., 2003, 22, 476-85.
    • (2003) Human Mutat. , vol.22 , pp. 476-485
    • Schaeffeler, E.1    Schwab, M.2    Eichelbaum, M.3    Zanger, U.4
  • 14
    • 0029622336 scopus 로고
    • An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis
    • BROLY F., MAREZ D., SABBAGH N., LEGRAND M., MILLESCAMPS S., LOGUIDICE JM., et al. - An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis. Pharmacogenetics, 1995, 5, 373-84.
    • (1995) Pharmacogenetics , vol.5 , pp. 373-384
    • Broly, F.1    Marez, D.2    Sabbagh, N.3    Legrand, M.4    Millescamps, S.5    Loguidice, J.M.6
  • 15
    • 0036204756 scopus 로고    scopus 로고
    • Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs
    • BERTILSSON L., DAHL M., DALEN P., AL-SHURBAJI A. - Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs. Br. J. Clin. Pharmacol., 2002, 53, 111-22.
    • (2002) Br. J. Clin. Pharmacol. , vol.53 , pp. 111-122
    • Bertilsson, L.1    Dahl, M.2    Dalen, P.3    Al-Shurbaji, A.4
  • 16
    • 0034966799 scopus 로고    scopus 로고
    • Pharmacogenetics: A new diagnostic tool in the management of antidepressive drug therapy
    • STEIMER W., MULLER B., LEUCHT S., KISSLING W. - Pharmacogenetics: a new diagnostic tool in the management of antidepressive drug therapy. Clin. Chim. Acta, 2001, 308, 33-41.
    • (2001) Clin. Chim. Acta , vol.308 , pp. 33-41
    • Steimer, W.1    Muller, B.2    Leucht, S.3    Kissling, W.4
  • 17
    • 0014128388 scopus 로고
    • Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds
    • HAMMER W., SJÖQVIST F. - Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds. Life Sci., 1967, 8, 1895-903.
    • (1967) Life Sci. , vol.8 , pp. 1895-1903
    • Hammer, W.1    Sjöqvist, F.2
  • 18
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
    • JOHANSSON I., LUNDQVIST E., BERTILSSON L., DAHL ML., SJÖQVIST F., INGELMAN-SUNDBERG M. - Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc. Natl. Acad. Sci. USA, 1993, 90, 11825-9.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.L.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6
  • 19
    • 0032847652 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of antidepressants: Cost implications and relevance to clinical practice
    • BURKE MJ., PRESKORN SH. - Therapeutic drug monitoring of antidepressants: cost implications and relevance to clinical practice. Clin. Pharmacokinet., 1999, 37, 147-85.
    • (1999) Clin. Pharmacokinet. , vol.37 , pp. 147-185
    • Burke, M.J.1    Preskorn, S.H.2
  • 20
    • 10544248170 scopus 로고    scopus 로고
    • The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: Sreening costs and influence on clinical outcomes in psychiatry
    • CHEN S., CHOU WH., BLOUIN RA., MAO Z., HUMPHRIES LL., MEEK QC. et al. - The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: sreening costs and influence on clinical outcomes in psychiatry. Clin. Pharmacol. Ther., 1996, 60, 522-34.
    • (1996) Clin. Pharmacol. Ther. , vol.60 , pp. 522-534
    • Chen, S.1    Chou, W.H.2    Blouin, R.A.3    Mao, Z.4    Humphries, L.L.5    Meek, Q.C.6
  • 21
    • 1242269894 scopus 로고    scopus 로고
    • Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: Ultrarapid metabolism of antidepressants as a cause of non response. A pilot study
    • KAWANISHI C., LUNDGREN S., AGREN H., BERTILSSON L. - Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of non response. A pilot study. Eur. J. Clin. Pharmacol., 2004, 59, 803-7.
    • (2004) Eur. J. Clin. Pharmacol. , vol.59 , pp. 803-807
    • Kawanishi, C.1    Lundgren, S.2    Agren, H.3    Bertilsson, L.4
  • 22
    • 0034894010 scopus 로고    scopus 로고
    • CYP2D6 and CYP2C19 genotype-based deose recommendations for anti-depressants: A first step towards subpopulation-specific dosages
    • KIRCHLEINER J., BROSEN K., DAHL M., GRAM LF., KASPER S., ROOTS I. et al. - CYP2D6 and CYP2C19 genotype-based deose recommendations for anti-depressants: a first step towards subpopulation-specific dosages. Acta Psychiatr. Scand. 2001, 104, 173-692.
    • (2001) Acta Psychiatr. Scand. , vol.104 , pp. 173-692
    • Kirchleiner, J.1    Brosen, K.2    Dahl, M.3    Gram, L.F.4    Kasper, S.5    Roots, I.6
  • 23
    • 0242312707 scopus 로고    scopus 로고
    • Drug methylation in cancer therapy: Lessons from the TPMT polymorphism
    • KRYNETSKI E., EVANS W. - Drug methylation in cancer therapy: lessons from the TPMT polymorphism. Oncogene 2003, 22, 7403-13.
    • (2003) Oncogene , vol.22 , pp. 7403-7413
    • Krynetski, E.1    Evans, W.2
  • 24
    • 0028044714 scopus 로고
    • Thiopurine methyltransferase activity in american white subjects and black subjects
    • MCLEOD H., LIN J., SCOOT E., PUI C., EVANS W. - Thiopurine methyltransferase activity in american white subjects and black subjects. Clin. Pharmacol. Ther., 1994, 55, 15-20.
    • (1994) Clin. Pharmacol. Ther. , vol.55 , pp. 15-20
    • McLeod, H.1    Lin, J.2    Scoot, E.3    Pui, C.4    Evans, W.5
  • 25
    • 0035871560 scopus 로고    scopus 로고
    • Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
    • EVANS WE., HON Y., BOMGAARS L., COUTRE S., HOLDSWORTH M., JANCO R. et al. - Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J. Clin. Oncol., 2001, 19, 2293-301.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 2293-2301
    • Evans, W.E.1    Hon, Y.2    Bomgaars, L.3    Coutre, S.4    Holdsworth, M.5    Janco, R.6
  • 26
    • 0033486029 scopus 로고    scopus 로고
    • Mercaptopurine therapy intolerance and heterozygoty at the thiopurine S-methyl-transferase gene locus
    • RELLING M., HANCOK M., RIVIERA G. et al. - Mercaptopurine therapy intolerance and heterozygoty at the thiopurine S-methyl-transferase gene locus. J. Natl. Cancer Inst., 1999, 91, 2001-8.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 2001-2008
    • Relling, M.1    Hancok, M.2    Riviera, G.3
  • 27
    • 0032801395 scopus 로고    scopus 로고
    • Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recippients treated with azathioprine
    • DERVIEUX T., MEDARD Y., BAUDOUIN V. et al. - Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recippients treated with azathioprine. Br. J. Clin. Pharmacol. 1999, 48, 793-800.
    • (1999) Br. J. Clin. Pharmacol. , vol.48 , pp. 793-800
    • Dervieux, T.1    Medard, Y.2    Baudouin, V.3
  • 28
    • 0014398534 scopus 로고
    • Comparison of the isoniazid inactivation in Finns and Lapons
    • TITINEN H., MATTILA MJ., ERIKSSON AW. - Comparison of the isoniazid inactivation in Finns and Lapons. Ann. Med. Intern. Fenn., 1968, 57, 161-166.
    • (1968) Ann. Med. Intern. Fenn. , vol.57 , pp. 161-166
    • Titinen, H.1    Mattila, M.J.2    Eriksson, A.W.3
  • 30
    • 0017191066 scopus 로고
    • Variations between individuals and populations in acetylation of isoniazid and its significance for the treatment of pulmonary tuberculosis
    • ELLARD JA. - Variations between individuals and populations in acetylation of isoniazid and its significance for the treatment of pulmonary tuberculosis. Clin. Pharmacol., 1976, 19, 610.
    • (1976) Clin. Pharmacol. , vol.19 , pp. 610
    • Ellard, J.A.1
  • 31
    • 0026716854 scopus 로고
    • Genetically determined differences in drug metabolism as a risk factor in drug toxicity
    • EICHELBAUM M., KROEMER MK., MIKUS G. - Genetically determined differences in drug metabolism as a risk factor in drug toxicity. Toxicol. Lett. Spec. 1992, 64-65, 115-122.
    • (1992) Toxicol. Lett. Spec. , vol.64-65 , pp. 115-122
    • Eichelbaum, M.1    Kroemer, M.K.2    Mikus, G.3
  • 32
    • 17644441355 scopus 로고    scopus 로고
    • Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicine-induced hepatotoxicity
    • OHNO M., YAMAGUCHI I., YAMAMOTO I. et al. - Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicine-induced hepatotoxicity. Int. J. Tuberc. Lung Dis., 2000, 4, 256-261.
    • (2000) Int. J. Tuberc. Lung Dis. , vol.4 , pp. 256-261
    • Ohno, M.1    Yamaguchi, I.2    Yamamoto, I.3
  • 33
    • 20944449543 scopus 로고    scopus 로고
    • Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses?
    • KINZIG-SCHIPPERS M., TOMALIK-SCHARTE D., JETTER A. et al. - Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses? Antimicrob. Agents Chemother., 2005, 49, 1733-8.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 1733-1738
    • Kinzig-Schippers, M.1    Tomalik-Scharte, D.2    Jetter, A.3
  • 34
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • HOFFMEYER S., BURK O., von RITCHER O. et al. - Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA, 2000, 97, 3473-8.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    Von Ritcher, O.3
  • 35
    • 0038304548 scopus 로고    scopus 로고
    • Association of multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients
    • ANGLICHEAU D., VERSTUYFT C., LAURENT-PUIG T. et al. - Association of multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients. J. Am. Soc. Nephrol., 2003, 14, 1889-96.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 1889-1896
    • Anglicheau, D.1    Verstuyft, C.2    Laurent-Puig, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.