-
1
-
-
0032522873
-
Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
-
LAZAROU J., POMERANZ B., COREY P. - Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. J. Am. Med. Assoc., 1998, 279, 1200-5.
-
(1998)
J. Am. Med. Assoc.
, vol.279
, pp. 1200-1205
-
-
Lazarou, J.1
Pomeranz, B.2
Corey, P.3
-
2
-
-
0009829065
-
Admissions to hospital caused by adverse drugs reactions: Cross sectional incidence study
-
POUYANNE P., HARAMBURU F., IMBS J., BEGAUD B. - Admissions to hospital caused by adverse drugs reactions: cross sectional incidence study. Br. Med. J., 2000, 320, 1036.
-
(2000)
Br. Med. J.
, vol.320
, pp. 1036
-
-
Pouyanne, P.1
Haramburu, F.2
Imbs, J.3
Begaud, B.4
-
3
-
-
0027399842
-
Study of glucose-6-phosphate deshydrogenase: History and molecular biology
-
BEUTLER E. - Study of glucose-6-phosphate deshydrogenase: history and molecular biology. Am. J. Hematol., 1993, 42, 53-8.
-
(1993)
Am. J. Hematol.
, vol.42
, pp. 53-58
-
-
Beutler, E.1
-
4
-
-
26444539817
-
Genetic control of isoniazid metabolism in man
-
EVANS DAP., MANLEY KA., MCKUSICK VA. - Genetic control of isoniazid metabolism in man. Br. Med. J., 1960, 2, 485-91.
-
(1960)
Br. Med. J.
, vol.2
, pp. 485-491
-
-
Evans, D.A.P.1
Manley, K.A.2
McKusick, V.A.3
-
5
-
-
0032793249
-
Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment
-
INGELMANN-SUNDBERG M., OSCARSON M., MCLELLAN R. - Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment. TIPS, 1999, 20, 342-9.
-
(1999)
TIPS
, vol.20
, pp. 342-349
-
-
Ingelmann-Sundberg, M.1
Oscarson, M.2
McLellan, R.3
-
6
-
-
0037328994
-
Pharmacogenetics of the major polymorphic metabolising enzymes
-
DALY A. - Pharmacogenetics of the major polymorphic metabolising enzymes. Fundam. Clin. Pharmacol., 2003, 17, 27-41.
-
(2003)
Fundam. Clin. Pharmacol.
, vol.17
, pp. 27-41
-
-
Daly, A.1
-
7
-
-
0038294345
-
Pharmacogenetics of drug metabolising enzymes: Importance for personalised medecine
-
OSCARSON M. - Pharmacogenetics of drug metabolising enzymes: importance for personalised medecine. Clin. Chem. Lab. Med., 2003, 41, 573-80.
-
(2003)
Clin. Chem. Lab. Med.
, vol.41
, pp. 573-580
-
-
Oscarson, M.1
-
8
-
-
0030935086
-
Use of in vitro and in vivo data to estimate the likehood of metabolic pharmacokinetic interactions
-
BERTZ RJ., GRAMMENAM GR. - Use of in vitro and in vivo data to estimate the likehood of metabolic pharmacokinetic interactions. Clin. Pharmacokinet., 1997, 32, 210-258.
-
(1997)
Clin. Pharmacokinet.
, vol.32
, pp. 210-258
-
-
Bertz, R.J.1
Grammenam, G.R.2
-
9
-
-
0026254621
-
Genotype or phenotype: The definition of a pharmacogenetic polymorphism
-
MEYER U. - Genotype or phenotype: the definition of a pharmacogenetic polymorphism. Pharmacogenetics, 1991, 1, 66-7.
-
(1991)
Pharmacogenetics
, vol.1
, pp. 66-67
-
-
Meyer, U.1
-
10
-
-
0033973035
-
Interethnic differences of drug-metabolising enzymes
-
GAEDIGK A. - Interethnic differences of drug-metabolising enzymes. Int. J. Clin. Pharmacol. Ther., 2000, 38, 61-8.
-
(2000)
Int. J. Clin. Pharmacol. Ther.
, vol.38
, pp. 61-68
-
-
Gaedigk, A.1
-
11
-
-
4544292592
-
La pharmacogénétique ou la promesse d'une médecine personnalisée: Variations du métabolisme et du transport des médicaments
-
ALLORGE D., LORIOT MA. - La pharmacogénétique ou la promesse d'une médecine personnalisée: variations du métabolisme et du transport des médicaments. Ann. Biol. Clin., 2004, 62, 500-511.
-
(2004)
Ann. Biol. Clin.
, vol.62
, pp. 500-511
-
-
Allorge, D.1
Loriot, M.A.2
-
12
-
-
0742286803
-
Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
-
ZANGER U., RAIMUNDO S., EICHELBAUM M. - Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry. Naunyn-Schmiedeberg's Arch. Pharmacol., 2004, 369, 133-40.
-
(2004)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.369
, pp. 133-140
-
-
Zanger, U.1
Raimundo, S.2
Eichelbaum, M.3
-
13
-
-
0346363770
-
CYP2D6 genotyping strategy based on gene copy number determination by Taqman real-time PCR
-
SCHAEFFELER E., SCHWAB M., EICHELBAUM M., ZANGER U. - CYP2D6 genotyping strategy based on gene copy number determination by Taqman real-time PCR. Human Mutat., 2003, 22, 476-85.
-
(2003)
Human Mutat.
, vol.22
, pp. 476-485
-
-
Schaeffeler, E.1
Schwab, M.2
Eichelbaum, M.3
Zanger, U.4
-
14
-
-
0029622336
-
An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis
-
BROLY F., MAREZ D., SABBAGH N., LEGRAND M., MILLESCAMPS S., LOGUIDICE JM., et al. - An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis. Pharmacogenetics, 1995, 5, 373-84.
-
(1995)
Pharmacogenetics
, vol.5
, pp. 373-384
-
-
Broly, F.1
Marez, D.2
Sabbagh, N.3
Legrand, M.4
Millescamps, S.5
Loguidice, J.M.6
-
15
-
-
0036204756
-
Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs
-
BERTILSSON L., DAHL M., DALEN P., AL-SHURBAJI A. - Molecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugs. Br. J. Clin. Pharmacol., 2002, 53, 111-22.
-
(2002)
Br. J. Clin. Pharmacol.
, vol.53
, pp. 111-122
-
-
Bertilsson, L.1
Dahl, M.2
Dalen, P.3
Al-Shurbaji, A.4
-
16
-
-
0034966799
-
Pharmacogenetics: A new diagnostic tool in the management of antidepressive drug therapy
-
STEIMER W., MULLER B., LEUCHT S., KISSLING W. - Pharmacogenetics: a new diagnostic tool in the management of antidepressive drug therapy. Clin. Chim. Acta, 2001, 308, 33-41.
-
(2001)
Clin. Chim. Acta
, vol.308
, pp. 33-41
-
-
Steimer, W.1
Muller, B.2
Leucht, S.3
Kissling, W.4
-
17
-
-
0014128388
-
Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds
-
HAMMER W., SJÖQVIST F. - Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds. Life Sci., 1967, 8, 1895-903.
-
(1967)
Life Sci.
, vol.8
, pp. 1895-1903
-
-
Hammer, W.1
Sjöqvist, F.2
-
18
-
-
0027136288
-
Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
-
JOHANSSON I., LUNDQVIST E., BERTILSSON L., DAHL ML., SJÖQVIST F., INGELMAN-SUNDBERG M. - Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc. Natl. Acad. Sci. USA, 1993, 90, 11825-9.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11825-11829
-
-
Johansson, I.1
Lundqvist, E.2
Bertilsson, L.3
Dahl, M.L.4
Sjöqvist, F.5
Ingelman-Sundberg, M.6
-
19
-
-
0032847652
-
Therapeutic drug monitoring of antidepressants: Cost implications and relevance to clinical practice
-
BURKE MJ., PRESKORN SH. - Therapeutic drug monitoring of antidepressants: cost implications and relevance to clinical practice. Clin. Pharmacokinet., 1999, 37, 147-85.
-
(1999)
Clin. Pharmacokinet.
, vol.37
, pp. 147-185
-
-
Burke, M.J.1
Preskorn, S.H.2
-
20
-
-
10544248170
-
The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: Sreening costs and influence on clinical outcomes in psychiatry
-
CHEN S., CHOU WH., BLOUIN RA., MAO Z., HUMPHRIES LL., MEEK QC. et al. - The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: sreening costs and influence on clinical outcomes in psychiatry. Clin. Pharmacol. Ther., 1996, 60, 522-34.
-
(1996)
Clin. Pharmacol. Ther.
, vol.60
, pp. 522-534
-
-
Chen, S.1
Chou, W.H.2
Blouin, R.A.3
Mao, Z.4
Humphries, L.L.5
Meek, Q.C.6
-
21
-
-
1242269894
-
Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: Ultrarapid metabolism of antidepressants as a cause of non response. A pilot study
-
KAWANISHI C., LUNDGREN S., AGREN H., BERTILSSON L. - Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of non response. A pilot study. Eur. J. Clin. Pharmacol., 2004, 59, 803-7.
-
(2004)
Eur. J. Clin. Pharmacol.
, vol.59
, pp. 803-807
-
-
Kawanishi, C.1
Lundgren, S.2
Agren, H.3
Bertilsson, L.4
-
22
-
-
0034894010
-
CYP2D6 and CYP2C19 genotype-based deose recommendations for anti-depressants: A first step towards subpopulation-specific dosages
-
KIRCHLEINER J., BROSEN K., DAHL M., GRAM LF., KASPER S., ROOTS I. et al. - CYP2D6 and CYP2C19 genotype-based deose recommendations for anti-depressants: a first step towards subpopulation-specific dosages. Acta Psychiatr. Scand. 2001, 104, 173-692.
-
(2001)
Acta Psychiatr. Scand.
, vol.104
, pp. 173-692
-
-
Kirchleiner, J.1
Brosen, K.2
Dahl, M.3
Gram, L.F.4
Kasper, S.5
Roots, I.6
-
23
-
-
0242312707
-
Drug methylation in cancer therapy: Lessons from the TPMT polymorphism
-
KRYNETSKI E., EVANS W. - Drug methylation in cancer therapy: lessons from the TPMT polymorphism. Oncogene 2003, 22, 7403-13.
-
(2003)
Oncogene
, vol.22
, pp. 7403-7413
-
-
Krynetski, E.1
Evans, W.2
-
24
-
-
0028044714
-
Thiopurine methyltransferase activity in american white subjects and black subjects
-
MCLEOD H., LIN J., SCOOT E., PUI C., EVANS W. - Thiopurine methyltransferase activity in american white subjects and black subjects. Clin. Pharmacol. Ther., 1994, 55, 15-20.
-
(1994)
Clin. Pharmacol. Ther.
, vol.55
, pp. 15-20
-
-
McLeod, H.1
Lin, J.2
Scoot, E.3
Pui, C.4
Evans, W.5
-
25
-
-
0035871560
-
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
-
EVANS WE., HON Y., BOMGAARS L., COUTRE S., HOLDSWORTH M., JANCO R. et al. - Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J. Clin. Oncol., 2001, 19, 2293-301.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 2293-2301
-
-
Evans, W.E.1
Hon, Y.2
Bomgaars, L.3
Coutre, S.4
Holdsworth, M.5
Janco, R.6
-
26
-
-
0033486029
-
Mercaptopurine therapy intolerance and heterozygoty at the thiopurine S-methyl-transferase gene locus
-
RELLING M., HANCOK M., RIVIERA G. et al. - Mercaptopurine therapy intolerance and heterozygoty at the thiopurine S-methyl-transferase gene locus. J. Natl. Cancer Inst., 1999, 91, 2001-8.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 2001-2008
-
-
Relling, M.1
Hancok, M.2
Riviera, G.3
-
27
-
-
0032801395
-
Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recippients treated with azathioprine
-
DERVIEUX T., MEDARD Y., BAUDOUIN V. et al. - Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recippients treated with azathioprine. Br. J. Clin. Pharmacol. 1999, 48, 793-800.
-
(1999)
Br. J. Clin. Pharmacol.
, vol.48
, pp. 793-800
-
-
Dervieux, T.1
Medard, Y.2
Baudouin, V.3
-
28
-
-
0014398534
-
Comparison of the isoniazid inactivation in Finns and Lapons
-
TITINEN H., MATTILA MJ., ERIKSSON AW. - Comparison of the isoniazid inactivation in Finns and Lapons. Ann. Med. Intern. Fenn., 1968, 57, 161-166.
-
(1968)
Ann. Med. Intern. Fenn.
, vol.57
, pp. 161-166
-
-
Titinen, H.1
Mattila, M.J.2
Eriksson, A.W.3
-
29
-
-
0034960840
-
Population screening for isoniazid acetylator phenotype
-
SEIFART HI., PARKIN DP., BOTHA FJ., DONALD PR., VAN DER WATT BJ. - Population screening for isoniazid acetylator phenotype. Pharmaco-epidemiol. Drug Safety, 2001, 10, 127-134.
-
(2001)
Pharmaco-Epidemiol. Drug Safety
, vol.10
, pp. 127-134
-
-
Seifart, H.I.1
Parkin, D.P.2
Botha, F.J.3
Donald, P.R.4
Van Der Watt, B.J.5
-
30
-
-
0017191066
-
Variations between individuals and populations in acetylation of isoniazid and its significance for the treatment of pulmonary tuberculosis
-
ELLARD JA. - Variations between individuals and populations in acetylation of isoniazid and its significance for the treatment of pulmonary tuberculosis. Clin. Pharmacol., 1976, 19, 610.
-
(1976)
Clin. Pharmacol.
, vol.19
, pp. 610
-
-
Ellard, J.A.1
-
31
-
-
0026716854
-
Genetically determined differences in drug metabolism as a risk factor in drug toxicity
-
EICHELBAUM M., KROEMER MK., MIKUS G. - Genetically determined differences in drug metabolism as a risk factor in drug toxicity. Toxicol. Lett. Spec. 1992, 64-65, 115-122.
-
(1992)
Toxicol. Lett. Spec.
, vol.64-65
, pp. 115-122
-
-
Eichelbaum, M.1
Kroemer, M.K.2
Mikus, G.3
-
32
-
-
17644441355
-
Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicine-induced hepatotoxicity
-
OHNO M., YAMAGUCHI I., YAMAMOTO I. et al. - Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicine-induced hepatotoxicity. Int. J. Tuberc. Lung Dis., 2000, 4, 256-261.
-
(2000)
Int. J. Tuberc. Lung Dis.
, vol.4
, pp. 256-261
-
-
Ohno, M.1
Yamaguchi, I.2
Yamamoto, I.3
-
33
-
-
20944449543
-
Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses?
-
KINZIG-SCHIPPERS M., TOMALIK-SCHARTE D., JETTER A. et al. - Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses? Antimicrob. Agents Chemother., 2005, 49, 1733-8.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 1733-1738
-
-
Kinzig-Schippers, M.1
Tomalik-Scharte, D.2
Jetter, A.3
-
34
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
HOFFMEYER S., BURK O., von RITCHER O. et al. - Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA, 2000, 97, 3473-8.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Ritcher, O.3
-
35
-
-
0038304548
-
Association of multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients
-
ANGLICHEAU D., VERSTUYFT C., LAURENT-PUIG T. et al. - Association of multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients. J. Am. Soc. Nephrol., 2003, 14, 1889-96.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 1889-1896
-
-
Anglicheau, D.1
Verstuyft, C.2
Laurent-Puig, T.3
|