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Volumn 32, Issue 4, 2006, Pages 372-380

Risk factors for thrombosis and bleeding and their influence on therapeutic decisions in patients with essential thrombocythemia

Author keywords

Essential thrombocythemia; Risk factors; Therapy

Indexed keywords

ANAGRELIDE; HYDROXYUREA; JANUS KINASE 2; MOLECULAR MARKER; PRV 1 PROTEIN; THROMBOPOIETIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 33745728719     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-942758     Document Type: Review
Times cited : (28)

References (63)
  • 1
    • 25844456843 scopus 로고    scopus 로고
    • Essential thrombocythemia
    • Finazzi G, Harrison C. Essential thrombocythemia. Semin Hematol 2005;42(4):230-238
    • (2005) Semin Hematol , vol.42 , Issue.4 , pp. 230-238
    • Finazzi, G.1    Harrison, C.2
  • 2
    • 20444502966 scopus 로고    scopus 로고
    • Risk-adapted therapy in essential thrombocythemia and polycythemia vera
    • Finazzi G, Barbui T. Risk-adapted therapy in essential thrombocythemia and polycythemia vera. Blood Rev 2005; 19(5):243-252
    • (2005) Blood Rev , vol.19 , Issue.5 , pp. 243-252
    • Finazzi, G.1    Barbui, T.2
  • 3
    • 21444457418 scopus 로고    scopus 로고
    • When and how to treat essential thrombocythemia
    • Barbui T, Finazzi G. When and how to treat essential thrombocythemia. N Engl J Med 2005;353(1):85-86
    • (2005) N Engl J Med , vol.353 , Issue.1 , pp. 85-86
    • Barbui, T.1    Finazzi, G.2
  • 4
    • 0036307706 scopus 로고    scopus 로고
    • The risk of thrombosis in essential thrombocythemia and polycythemia vera
    • Pearson TC. The risk of thrombosis in essential thrombocythemia and polycythemia vera. Semin Oncol 2002;29(suppl 10):16-21
    • (2002) Semin Oncol , vol.29 , Issue.SUPPL. 10 , pp. 16-21
    • Pearson, T.C.1
  • 5
    • 0021914091 scopus 로고
    • Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia
    • Michiels JJ, Abels J, Steketee J, van Vliet HHDM, Vuzevski VD. Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia. Ann Intern Med 1985;102:466-471
    • (1985) Ann Intern Med , vol.102 , pp. 466-471
    • Michiels, J.J.1    Abels, J.2    Steketee, J.3    Van Vliet, H.H.D.M.4    Vuzevski, V.D.5
  • 6
    • 0032909014 scopus 로고    scopus 로고
    • Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia
    • Michiels JJ. Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia. Clin Appl Thromb Hemost 1999;5:30-36
    • (1999) Clin Appl Thromb Hemost , vol.5 , pp. 30-36
    • Michiels, J.J.1
  • 7
    • 0029152021 scopus 로고
    • Hydroxyurea in essential thrombocytosis
    • Van Genderen P, Michiels JJ. Hydroxyurea in essential thrombocytosis. N Engl J Med 1995;333:802-803
    • (1995) N Engl J Med , vol.333 , pp. 802-803
    • Van Genderen, P.1    Michiels, J.J.2
  • 8
  • 9
    • 0023840798 scopus 로고
    • Controlled and uncontrolled thrombocytosis. Its clinical role in essential thrombocythemia
    • Lahuerta-Palacios JJ, Bornstein R, Fernandez-Debora FJ, et al. Controlled and uncontrolled thrombocytosis. Its clinical role in essential thrombocythemia. Cancer 1988;61(6):1207-1212
    • (1988) Cancer , vol.61 , Issue.6 , pp. 1207-1212
    • Lahuerta-Palacios, J.J.1    Bornstein, R.2    Fernandez-Debora, F.J.3
  • 10
    • 0025213422 scopus 로고
    • Incidence and risk factors for thrombotic complications in a historical cohort of 100 patients with essential thrombocythemia
    • Cortelazzo S, Viero P, Finazzi G, D'Emilio A, Rodeghiero F, Barbui T. Incidence and risk factors for thrombotic complications in a historical cohort of 100 patients with essential thrombocythemia. J Clin Oncol 1990;8(3):556-562
    • (1990) J Clin Oncol , vol.8 , Issue.3 , pp. 556-562
    • Cortelazzo, S.1    Viero, P.2    Finazzi, G.3    D'Emilio, A.4    Rodeghiero, F.5    Barbui, T.6
  • 11
    • 0028913012 scopus 로고
    • Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis
    • Cortelazzo S, Finazzi G, Ruggeri M, et al. Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis. N Engl J Med 1995;332(17):1132-1136
    • (1995) N Engl J Med , vol.332 , Issue.17 , pp. 1132-1136
    • Cortelazzo, S.1    Finazzi, G.2    Ruggeri, M.3
  • 12
    • 0033781129 scopus 로고    scopus 로고
    • Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: Long-term follow-up of a randomized clinical trial
    • Finazzi G, Ruggeri M, Rodeghiero F, Barbui T. Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: long-term follow-up of a randomized clinical trial. Br J Haematol 2000;110(3):577-583
    • (2000) Br J Haematol , vol.110 , Issue.3 , pp. 577-583
    • Finazzi, G.1    Ruggeri, M.2    Rodeghiero, F.3    Barbui, T.4
  • 13
    • 0035865604 scopus 로고    scopus 로고
    • Long-term use of anagrelide in young patients with essential thrombocythemia
    • Storen EC, Tefferi A. Long-term use of anagrelide in young patients with essential thrombocythemia. Blood 2001;97(4):863-866
    • (2001) Blood , vol.97 , Issue.4 , pp. 863-866
    • Storen, E.C.1    Tefferi, A.2
  • 14
    • 6844261163 scopus 로고    scopus 로고
    • Should a platelet limit of 600 × 10(9)/L be used as a diagnostic criterion in essential thrombocythaemia? An analysis of the natural course including early stages
    • Lengfelder E, Hochhaus A, Kronawitter U, et al. Should a platelet limit of 600 × 10(9)/L be used as a diagnostic criterion in essential thrombocythaemia? An analysis of the natural course including early stages. Br J Haematol 1998;100(1):15-23
    • (1998) Br J Haematol , vol.100 , Issue.1 , pp. 15-23
    • Lengfelder, E.1    Hochhaus, A.2    Kronawitter, U.3
  • 15
    • 28944455594 scopus 로고    scopus 로고
    • Long-term outcome of 231 patients with essential thrombocythemia
    • Chim C-S, Kwong Y-K, Lie AK-W, et al. Long-term outcome of 231 patients with essential thrombocythemia. Arch Intern Med 2005;165:2651-2658
    • (2005) Arch Intern Med , vol.165 , pp. 2651-2658
    • Chim, C.-S.1    Kwong, Y.-K.2    Lie, A.K.-W.3
  • 16
    • 0030707621 scopus 로고    scopus 로고
    • Thrombotic complications in essential thrombocythemia with relatively low platelet counts
    • Regev A, Stark P, Blickstein D, Lahav M. Thrombotic complications in essential thrombocythemia with relatively low platelet counts. Am J Hematol 1997;56(3):168-172
    • (1997) Am J Hematol , vol.56 , Issue.3 , pp. 168-172
    • Regev, A.1    Stark, P.2    Blickstein, D.3    Lahav, M.4
  • 17
    • 0028118495 scopus 로고
    • Erythromelalgic, thrombotic and haemorrhagic manifestations of thrombocythaemia
    • van Genderen PJ, Michiels JJ. Erythromelalgic, thrombotic and haemorrhagic manifestations of thrombocythaemia. Presse Med 1994;23(2):73-77
    • (1994) Presse Med , vol.23 , Issue.2 , pp. 73-77
    • Van Genderen, P.J.1    Michiels, J.J.2
  • 18
    • 0029954991 scopus 로고    scopus 로고
    • Acquired von Willebrand disease in myeloproliferative disorders
    • van Genderen PJ, Leenknegt H, Michiels JJ, Budde U. Acquired von Willebrand disease in myeloproliferative disorders. Leuk Lymphoma 1996;22(suppl 1):79-82
    • (1996) Leuk Lymphoma , vol.22 , Issue.SUPPL. 1 , pp. 79-82
    • Van Genderen, P.J.1    Leenknegt, H.2    Michiels, J.J.3    Budde, U.4
  • 21
    • 0022862698 scopus 로고
    • Subunit composition of plasma von Willebrand factor in patients with the myleproloferative syndrome
    • Budde U, Dent JA, Berkovitz SD, Ruggeri ZM, Zimmerman TS. Subunit composition of plasma von Willebrand factor in patients with the myleproloferative syndrome. Blood 1986;68:1213-1217
    • (1986) Blood , vol.68 , pp. 1213-1217
    • Budde, U.1    Dent, J.A.2    Berkovitz, S.D.3    Ruggeri, Z.M.4    Zimmerman, T.S.5
  • 22
    • 0022649246 scopus 로고
    • Abnormalities of von Willebrand factor in myeloproliferative disease: A relationship with bleeding diathesis
    • Fabris F, Casonato A, DelBen MG, DeMarco L, Girolami A. Abnormalities of von Willebrand factor in myeloproliferative disease: a relationship with bleeding diathesis. Br J Haematol 1986;63:75-83
    • (1986) Br J Haematol , vol.63 , pp. 75-83
    • Fabris, F.1    Casonato, A.2    Delben, M.G.3    Demarco, L.4    Girolami, A.5
  • 23
    • 2942579910 scopus 로고    scopus 로고
    • Practice guidelines for the therapy of essential thrombocythemia. A statement from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation
    • Barbui T, Barosi G, Grossi A, et al. Practice guidelines for the therapy of essential thrombocythemia. A statement from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation. Haematologica 2004;89(2):215-232
    • (2004) Haematologica , vol.89 , Issue.2 , pp. 215-232
    • Barbui, T.1    Barosi, G.2    Grossi, A.3
  • 24
    • 0025801628 scopus 로고
    • Thrombotic and hemorrhagic complications in essential thrombocythemia. A retrospective study of 103 patients
    • Colombi M, Radaelli F, Zocchi L, Maiolo AT. Thrombotic and hemorrhagic complications in essential thrombocythemia. A retrospective study of 103 patients. Cancer 1991;67(11):2926-2930
    • (1991) Cancer , vol.67 , Issue.11 , pp. 2926-2930
    • Colombi, M.1    Radaelli, F.2    Zocchi, L.3    Maiolo, A.T.4
  • 25
    • 0033000430 scopus 로고    scopus 로고
    • Major vascular complications in essential thrombocythemia: A study of the predictive factors in a series of 148 patients
    • Besses C, Cervantes F, Pereira A, et al. Major vascular complications in essential thrombocythemia: a study of the predictive factors in a series of 148 patients. Leukemia 1999; 13(2):150-154
    • (1999) Leukemia , vol.13 , Issue.2 , pp. 150-154
    • Besses, C.1    Cervantes, F.2    Pereira, A.3
  • 26
    • 0035160530 scopus 로고    scopus 로고
    • A long-term retrospective study of young women with essential thrombocythemia
    • Tefferi A, Fonseca R, Pereira DL, Hoagland HC. A long-term retrospective study of young women with essential thrombocythemia. Mayo Clin Proc 2001;76(1):22-28
    • (2001) Mayo Clin Proc , vol.76 , Issue.1 , pp. 22-28
    • Tefferi, A.1    Fonseca, R.2    Pereira, D.L.3    Hoagland, H.C.4
  • 27
  • 28
    • 0032723580 scopus 로고    scopus 로고
    • Essential thrombocythemia in young adults: Treatment and outcome of 16 pregnancies
    • Randi ML, Rossi C, Fabris F, Girolami A. Essential thrombocythemia in young adults: treatment and outcome of 16 pregnancies. J Intern Med 1999;246(5):517-518
    • (1999) J Intern Med , vol.246 , Issue.5 , pp. 517-518
    • Randi, M.L.1    Rossi, C.2    Fabris, F.3    Girolami, A.4
  • 29
    • 0036720394 scopus 로고    scopus 로고
    • Predictive values of X-chromosome inactivation patterns and clinicohematologic parameters for vascular complications in female patients with essential thrombocythemia
    • Shih LY, Lin TL, Lai CL, et al. Predictive values of X-chromosome inactivation patterns and clinicohematologic parameters for vascular complications in female patients with essential thrombocythemia. Blood 2002;100(5):1596-1601
    • (2002) Blood , vol.100 , Issue.5 , pp. 1596-1601
    • Shih, L.Y.1    Lin, T.L.2    Lai, C.L.3
  • 30
    • 0027537177 scopus 로고
    • Vascular complications of essential thrombocythaemia: A link to cardiovascular risk factors
    • Watson KV, Key N. Vascular complications of essential thrombocythaemia: a link to cardiovascular risk factors. Br J Haematol 1993;83(2):198-203
    • (1993) Br J Haematol , vol.83 , Issue.2 , pp. 198-203
    • Watson, K.V.1    Key, N.2
  • 31
    • 0035112570 scopus 로고    scopus 로고
    • The predictive value of vascular risk factors and gender for the development of thrombotic complications in essential thrombocythemia
    • Jantunen R, Juvonen E, Ikkala E, Oksanen K, Anttila P, Ruutu T. The predictive value of vascular risk factors and gender for the development of thrombotic complications in essential thrombocythemia. Ann Hematol 2001;80(2):74-78
    • (2001) Ann Hematol , vol.80 , Issue.2 , pp. 74-78
    • Jantunen, R.1    Juvonen, E.2    Ikkala, E.3    Oksanen, K.4    Anttila, P.5    Ruutu, T.6
  • 32
    • 0036176284 scopus 로고    scopus 로고
    • Frequent occurrence of anticardiolipin antibodies, Factor V Leiden mutation, and perturbed endothelial function in chronic myeloproliferative disorders
    • Jensen MK, de Nully Brown P, Thorsen S, Hasselbalch HC. Frequent occurrence of anticardiolipin antibodies, Factor V Leiden mutation, and perturbed endothelial function in chronic myeloproliferative disorders. Am J Hematol 2002; 69(3):185-191
    • (2002) Am J Hematol , vol.69 , Issue.3 , pp. 185-191
    • Jensen, M.K.1    De Nully Brown, P.2    Thorsen, S.3    Hasselbalch, H.C.4
  • 34
    • 0029877730 scopus 로고    scopus 로고
    • Reduction of antithrombin III, protein C, and protein S levels and activated protein C resistance in polycythemia vera and essential thrombocythemia patients with thrombosis
    • Bucalossi A, Marotta G, Bigazzi C, Galieni P, Dispensa E. Reduction of antithrombin III, protein C, and protein S levels and activated protein C resistance in polycythemia vera and essential thrombocythemia patients with thrombosis. Am J Hematol 1996;52(1):14-20
    • (1996) Am J Hematol , vol.52 , Issue.1 , pp. 14-20
    • Bucalossi, A.1    Marotta, G.2    Bigazzi, C.3    Galieni, P.4    Dispensa, E.5
  • 35
    • 0023900982 scopus 로고
    • Essential thrombocythemia. Clinical characteristics and course of 61 cases
    • Hehlmann R, Jahn M, Baumann B, Kopeke W. Essential thrombocythemia. Clinical characteristics and course of 61 cases. Cancer 1988;61(12):2487-2496
    • (1988) Cancer , vol.61 , Issue.12 , pp. 2487-2496
    • Hehlmann, R.1    Jahn, M.2    Baumann, B.3    Kopeke, W.4
  • 36
    • 0030887759 scopus 로고    scopus 로고
    • Prevention and treatment of thrombotic complications in essential thrombocythaemia: Efficacy and safety of aspirin
    • van Genderen PJ, Mulder PG, Waleboer M, van de Moesdijk D, Michiels JJ. Prevention and treatment of thrombotic complications in essential thrombocythaemia: efficacy and safety of aspirin. Br J Haematol 1997;97(1):179-184
    • (1997) Br J Haematol , vol.97 , Issue.1 , pp. 179-184
    • Van Genderen, P.J.1    Mulder, P.G.2    Waleboer, M.3    Van De Moesdijk, D.4    Michiels, J.J.5
  • 37
    • 0036735354 scopus 로고    scopus 로고
    • Factor V Leiden mutation carriership and venous thromboembolism in polycythemia vera and essential thrombocythemia
    • Ruggeri M, Gisslinger H, Tosetto A, et al. Factor V Leiden mutation carriership and venous thromboembolism in polycythemia vera and essential thrombocythemia. Am J Hematol 2002;71(1):1-6
    • (2002) Am J Hematol , vol.71 , Issue.1 , pp. 1-6
    • Ruggeri, M.1    Gisslinger, H.2    Tosetto, A.3
  • 38
    • 2042477375 scopus 로고    scopus 로고
    • Hemostatic gene polymorphisms and the prevalence of thrombotic complications in polycythemia vera and essential thrombocythemia
    • Afshar-Kharghan V, Lopez JA, Gray LA, et al. Hemostatic gene polymorphisms and the prevalence of thrombotic complications in polycythemia vera and essential thrombocythemia. Blood Coagul Fibrinolysis 2004;15(1):21-24
    • (2004) Blood Coagul Fibrinolysis , vol.15 , Issue.1 , pp. 21-24
    • Afshar-Kharghan, V.1    Lopez, J.A.2    Gray, L.A.3
  • 39
    • 15244363669 scopus 로고    scopus 로고
    • Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: A cohort study
    • Gisslinger H, Mullner M, Pabinger I, et al. Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study. Haematologica 2005;90(3):408-410
    • (2005) Haematologica , vol.90 , Issue.3 , pp. 408-410
    • Gisslinger, H.1    Mullner, M.2    Pabinger, I.3
  • 40
    • 0345184883 scopus 로고    scopus 로고
    • Homocysteine levels in polycythaemia vera and essential thrombocythaemia
    • Gisslinger H, Rodeghiero F, Ruggeri M, et al. Homocysteine levels in polycythaemia vera and essential thrombocythaemia. Br J Haematol 1999;105(2):551-555
    • (1999) Br J Haematol , vol.105 , Issue.2 , pp. 551-555
    • Gisslinger, H.1    Rodeghiero, F.2    Ruggeri, M.3
  • 41
    • 0033832645 scopus 로고    scopus 로고
    • High prevalence of hyperhomocysteinemia due to marginal deficiency of cobalamin or folate in chronic myeloproliferative disorders
    • Faurschou M, Nielsen OJ, Jensen MK, Hasselbalch HC. High prevalence of hyperhomocysteinemia due to marginal deficiency of cobalamin or folate in chronic myeloproliferative disorders. Am J Hematol 2000;65(2):136-140
    • (2000) Am J Hematol , vol.65 , Issue.2 , pp. 136-140
    • Faurschou, M.1    Nielsen, O.J.2    Jensen, M.K.3    Hasselbalch, H.C.4
  • 42
    • 12244274339 scopus 로고    scopus 로고
    • Thrombophilic genotypes, natural anticoagulants, and plasma homocysteine in myeloproliferative disorders: Relationship with splanchnic vein thrombosis and arterial disease
    • Amitrano L, Guardascione MA, Ames PR, et al. Thrombophilic genotypes, natural anticoagulants, and plasma homocysteine in myeloproliferative disorders: relationship with splanchnic vein thrombosis and arterial disease. Am J Hematol 2003;72(2):75-81
    • (2003) Am J Hematol , vol.72 , Issue.2 , pp. 75-81
    • Amitrano, L.1    Guardascione, M.A.2    Ames, P.R.3
  • 43
    • 0036247965 scopus 로고    scopus 로고
    • Patients with essential thrombocythaemia have an increased prevalence of antiphospholipid antibodies which may be associated with thrombosis
    • Harrison CN, Donohoe S, Carr P, Dave M, Mackie I, Machin SJ. Patients with essential thrombocythaemia have an increased prevalence of antiphospholipid antibodies which may be associated with thrombosis. Thromb Haemost 2002; 87(5):802-807
    • (2002) Thromb Haemost , vol.87 , Issue.5 , pp. 802-807
    • Harrison, C.N.1    Donohoe, S.2    Carr, P.3    Dave, M.4    Mackie, I.5    Machin, S.J.6
  • 44
    • 0034808096 scopus 로고    scopus 로고
    • Hereditary thrombophilia as a cause of Budd-Chiari syndrome: A study from Western India
    • Mohanty D, Shetty S, Ghosh K, Pawar A, Abraham P. Hereditary thrombophilia as a cause of Budd-Chiari syndrome: a study from Western India. Hepatology 2001;34:666-670
    • (2001) Hepatology , vol.34 , pp. 666-670
    • Mohanty, D.1    Shetty, S.2    Ghosh, K.3    Pawar, A.4    Abraham, P.5
  • 45
    • 0034307368 scopus 로고    scopus 로고
    • Factor V Leiden mutation, prothrombin gene mutation and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis: Results of a case-control study
    • Janssen HL, Meinardi JR, Vleggaar FP, et al. Factor V Leiden mutation, prothrombin gene mutation and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis: results of a case-control study. Blood 2000;96:2364-2368
    • (2000) Blood , vol.96 , pp. 2364-2368
    • Janssen, H.L.1    Meinardi, J.R.2    Vleggaar, F.P.3
  • 46
    • 0033555392 scopus 로고    scopus 로고
    • A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications
    • Harrison CN, Gale RE, Machin SJ, Linch DC. A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications. Blood 1999;93(2):417-424
    • (1999) Blood , vol.93 , Issue.2 , pp. 417-424
    • Harrison, C.N.1    Gale, R.E.2    Machin, S.J.3    Linch, D.C.4
  • 47
    • 0034993370 scopus 로고    scopus 로고
    • Clonal hemopoiesis and risk of thrombosis in young female patients with essential thrombocythemia
    • Chiusolo P, La Barbera EO, Laurenti L, et al. Clonal hemopoiesis and risk of thrombosis in young female patients with essential thrombocythemia. Exp Hematol 2001;29(6):670-676
    • (2001) Exp Hematol , vol.29 , Issue.6 , pp. 670-676
    • Chiusolo, P.1    La Barbera, E.O.2    Laurenti, L.3
  • 48
    • 0037438644 scopus 로고    scopus 로고
    • Monoclonal myelopoiesis and subnormal erythropoietin concentration are independent risk factors for thromboembolic complications in essential thrombocythemia
    • Andreasson B, Harrison C, Lindstedt G, Linch D, Kutti J. Monoclonal myelopoiesis and subnormal erythropoietin concentration are independent risk factors for thromboembolic complications in essential thrombocythemia. Blood 2003;101(2):783
    • (2003) Blood , vol.101 , Issue.2 , pp. 783
    • Andreasson, B.1    Harrison, C.2    Lindstedt, G.3    Linch, D.4    Kutti, J.5
  • 49
    • 9644275709 scopus 로고    scopus 로고
    • Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders
    • Kralovics R, Skoda RC. Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders. Blood Rev 2005;19(1):1-13
    • (2005) Blood Rev , vol.19 , Issue.1 , pp. 1-13
    • Kralovics, R.1    Skoda, R.C.2
  • 50
    • 22544481483 scopus 로고    scopus 로고
    • Gain of function, loss of control - A molecular basis for chronic myeloproliferative disorders
    • Cazzola M, Skoda R. Gain of function, loss of control-a molecular basis for chronic myeloproliferative disorders. Haematologica 2005;90(7):871-874
    • (2005) Haematologica , vol.90 , Issue.7 , pp. 871-874
    • Cazzola, M.1    Skoda, R.2
  • 51
    • 25844461158 scopus 로고    scopus 로고
    • The Jak2V617F mutation, PRV-1 overexpression, and EEC formation define a similar cohort of MPD patients
    • Goerttler PS, Steimle C, Marz E, et al. The Jak2V617F mutation, PRV-1 overexpression, and EEC formation define a similar cohort of MPD patients. Blood 2005;106(8):2862-2864
    • (2005) Blood , vol.106 , Issue.8 , pp. 2862-2864
    • Goerttler, P.S.1    Steimle, C.2    Marz, E.3
  • 52
    • 0037100542 scopus 로고    scopus 로고
    • The expression pattern of c-mpl in megakaryocytes correlates with thrombotic risk in essential thrombocythemia
    • Teofili L, Pierconti F, Di Febo A, et al. The expression pattern of c-mpl in megakaryocytes correlates with thrombotic risk in essential thrombocythemia. Blood 2002;100(2):714-717
    • (2002) Blood , vol.100 , Issue.2 , pp. 714-717
    • Teofili, L.1    Pierconti, F.2    Di Febo, A.3
  • 53
    • 0242663394 scopus 로고    scopus 로고
    • Quantification of PRV-1 mRNA distinguishes polycythemia vera from secondary erythrocytosis
    • Klippel S, Strunck E, Temerinac S, et al. Quantification of PRV-1 mRNA distinguishes polycythemia vera from secondary erythrocytosis. Blood 2003;102(10):3569-3574
    • (2003) Blood , vol.102 , Issue.10 , pp. 3569-3574
    • Klippel, S.1    Strunck, E.2    Temerinac, S.3
  • 54
    • 0242266436 scopus 로고    scopus 로고
    • Increased risk for vascular complications in PRV-1 positive patients with essential thrombocythaemia
    • Johansson P, Ricksten A, Wennstrom L, Palmqvist L, Kutti J, Andreasson B. Increased risk for vascular complications in PRV-1 positive patients with essential thrombocythaemia. Br J Haematol 2003;123(3):513-516
    • (2003) Br J Haematol , vol.123 , Issue.3 , pp. 513-516
    • Johansson, P.1    Ricksten, A.2    Wennstrom, L.3    Palmqvist, L.4    Kutti, J.5    Andreasson, B.6
  • 55
    • 2542454747 scopus 로고    scopus 로고
    • PRV-1 mRNA expression discriminates two types of essential thrombocythemia
    • Griesshammer M, Klippel S, Strunck E, et al. PRV-1 mRNA expression discriminates two types of essential thrombocythemia. Ann Hematol 2004;83(6):364-370
    • (2004) Ann Hematol , vol.83 , Issue.6 , pp. 364-370
    • Griesshammer, M.1    Klippel, S.2    Strunck, E.3
  • 56
    • 21244487393 scopus 로고    scopus 로고
    • Thrombotic and bleeding complications in four subpopulations of patients with essential thrombocythemia defined by c-Mpl protein expression and PRV-1 mRNA levels
    • Goerttler PL, Marz E, Jhansson PL, et al. Thrombotic and bleeding complications in four subpopulations of patients with essential thrombocythemia defined by c-Mpl protein expression and PRV-1 mRNA levels. Haematologica 2005; 90(6):851-853
    • (2005) Haematologica , vol.90 , Issue.6 , pp. 851-853
    • Goerttler, P.L.1    Marz, E.2    Jhansson, P.L.3
  • 57
    • 17844383458 scopus 로고    scopus 로고
    • A unique donal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, et al. A unique donal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434(7037):1144-1148
    • (2005) Nature , vol.434 , Issue.7037 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 58
    • 27744606173 scopus 로고    scopus 로고
    • JAK2 mutation in essential thrombocythaemia: Clinical associations and long-term prognostic relevance
    • Wolanskyj AP, Lasho TL, Schwager SM, et al. JAK2 mutation in essential thrombocythaemia: clinical associations and long-term prognostic relevance. Br J Haematol 2005; 131(2):208-213
    • (2005) Br J Haematol , vol.131 , Issue.2 , pp. 208-213
    • Wolanskyj, A.P.1    Lasho, T.L.2    Schwager, S.M.3
  • 59
    • 27144443646 scopus 로고    scopus 로고
    • Clinical implications of the JAK2 V617F mutation in essential thrombocythemia
    • Antonioli E, Guglielmelli P, Pancrazzi A, et al. Clinical implications of the JAK2 V617F mutation in essential thrombocythemia. Leukemia 2005;19(10):1847-1849
    • (2005) Leukemia , vol.19 , Issue.10 , pp. 1847-1849
    • Antonioli, E.1    Guglielmelli, P.2    Pancrazzi, A.3
  • 60
    • 28244442441 scopus 로고    scopus 로고
    • Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: A prospective study
    • Campbell PJ, Scott LM, Buck G, et al. Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study. Lancet 2005;366(9501):1945-1953
    • (2005) Lancet , vol.366 , Issue.9501 , pp. 1945-1953
    • Campbell, P.J.1    Scott, L.M.2    Buck, G.3
  • 61
    • 13444256042 scopus 로고    scopus 로고
    • Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia
    • Elliott MA, Tefferi A. Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia. Br J Haematol 2005;128(3):275-290
    • (2005) Br J Haematol , vol.128 , Issue.3 , pp. 275-290
    • Elliott, M.A.1    Tefferi, A.2
  • 62
    • 33646474989 scopus 로고    scopus 로고
    • Clinical and laboratory features, and pathobiology of platelet-mediated microvascular disturbances, major thrombosis and bleeding complications and the molecular etiology of et and PV
    • Michiels JJ, Berneman Z, Van Bockstaele D, van der Planken M, De Raeve H, Schroyens W. Clinical and laboratory features, and pathobiology of platelet-mediated microvascular disturbances, major thrombosis and bleeding complications and the molecular etiology of ET and PV. Semin Thromb Hemost 2006;32:174-207
    • (2006) Semin Thromb Hemost , vol.32 , pp. 174-207
    • Michiels, J.J.1    Berneman, Z.2    Van Bockstaele, D.3    Van Der Planken, M.4    De Raeve, H.5    Schroyens, W.6
  • 63
    • 33745735078 scopus 로고    scopus 로고
    • Chronische myeloproliferative Erkrankungen
    • Herausgeber M, Classen R, Dierkesmann H, et al, eds. Rationelle Diagnostik und Therapie in der Inneren Medizin - Leitlinien. München, Germany: Verlag Urban und Fischer, Chapter B2
    • Griesshammer M, Hochhaus A. Chronische myeloproliferative Erkrankungen. In: Herausgeber M, Classen R, Dierkesmann H, et al, eds. für die deutsche Gesellschaft für Innere Medizin. Rationelle Diagnostik und Therapie in der Inneren Medizin - Leitlinien. München, Germany: Verlag Urban und Fischer, Vol. 13. 2002, Chapter B2
    • (2002) Für Die Deutsche Gesellschaft für Innere Medizin , vol.13
    • Griesshammer, M.1    Hochhaus, A.2


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