Prevention and treatment of thrombotic complications in essential thrombocythaemia: Efficacy and safety of aspirin

British Journal of Haematology

Volumn 97, Issue 1, 1997, Pages 179-184

  Van Genderen, Perry J J ^a   Mulder, Paul G H ^b   Waleboer, Marco ^a   Van De Moesdijk, Desiree ^a   Michiels, Jan J ^a,c  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c Goodheart Institute   (Netherlands)

Author keywords

aspirin; bleeding; essential thrombocythaemia; myeloproliferative disorder; thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; BUSULFAN; HYDROXYUREA;

ADULT; AGED; ARTICLE; BLEEDING; COHORT ANALYSIS; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; THROMBOCYTHEMIA; THROMBOSIS;

EID: 0030887759     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.d01-2127.x     Document Type: Article

References (27)

1. Baker, R.I. & Manoharan, A. (1988) Platelet function in myeloproliferative disorders: characterization and sequential studies show multiple platelet abnormalities, and change with time. European Journal of Haematology, 40, 267-272.
2. Barbui, T., Cortelazzo, S., Viero, P., Bassan, R., Dini, E. & Semeraro, N. (1983) Thrombohaemorrhagic complications in 101 cases of myeloproliferative disorders: relationship to platelet number and function. European Journal of Cancer and Clinical Oncology, 19, 1593-1599.
3. Bellucci, S., Janvier, M., Tobelem, G., Flandrin, G., Charpak, Y., Berger, R. & Boiron, M. (1986) Essential thrombocythemias: clinical, evolutionary and biological data. Cancer, 58, 2440-2447.
4. Budde, U., Schaefer, G., Mueller, N., Egli, H., Dent, J., Ruggeri, Z. & Zimmerman, T. (1984) Acquired von Willebrand's disease in the myeloproliferative syndrome. Blood, 64, 981-985.
5. Budde, U., Scharf, R., Franke, P., Hartmann-Budde, K., Dent, J. & Ruggeri, Z. (1993) Elevated platelet count as a cause of abnormal von Willebrand factor multimer distribution in plasma. Blood, 82, 1749-1757.
6. Colombi, M., Radaelli, F., Zocchi, L. & Maiolo, A. (1991) Thrombotic and hemorrhagic complications in essential thrombocythemia: a retrospective study of 103 patients. Cancer, 67, 2926-2930.
7. Cortelazzo, S., Finazzi, G., Ruggeri, M., Vestri, O., Galli, M., Rodeghiero, F. & Barbui, T. (1995) Hydroxyurea for patients with essential thrombocythemia and high risk of thrombosis. New England Journal of Medicine, 332, 1132-1136.
8. Cortelazzo, S., Viero, P., Finazzi, G, D'Emilio, A., Rodeghiero, F. & Barbui, T. (1990) Incidence and risk factors for thrombotic complications in a historical cohort of 100 patients with essential thrombocythemia. Journal of Clinical Oncology, 8, 556-562.
9. Fabris, F., Casonato, A., Del Ben, M., De Marco, L. & Girolami, A. (1986) Abnormalities of von Willebrand factor in myeloproliferative disease: a relationship with bleeding diathesis. British Journal of Haematology, 63, 75-83.
10. Fenaux, P., Simon, M., Caulier, M., Lai, J. & Goudemand, J. (1990) Clinical course of essential thrombocythemia. Cancer, 66, 549-556.
11. Grossi, A., Rosseti, S., Vannuchi, A., Rafanelli, D. & Ferrini, P. (1988) Occurrence of haemorrhagic and thrombotic events in myeloproliferative disorders: a retrospective study of 108 patients. Clinical and Laboratory Haematology, 10, 167-175.
12. Hehlmann, R., Jahn, M., Baumann, B. & Kopcke, W. (1988) Essential thrombocythemia: clinical characteristics and course of 61 cases. Cancer, 61, 2487-2496.
13. Kaplan, M., Mack, K. & Goldberg, J. (1986) Long term management of polycythemia vera with hydroxyurea: a progress report. Seminars in Hematology, 23, 167-171.
14. Landolfi, R. & Patrono, C. (1996) Aspirin in polycythemia vera and essential thrombocythemia: current facts and perspectives. Leukemia and Lymphoma, 22, (Suppl. 1), 83-86.
15. Michiels, J., Abels, J., Steketee, J., van Vliet, H. & Vuzevski, V. (1985) Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia. Annals of Internal Medicine, 102, 466-471.
16. Michiels, J., Koudstaal, P., Mulder, A. & van Vliet, H. (1993) Transient neurological and ocular manifestations in primary thrombocythemia. Neurology, 43, 1107-1110.
17. Preston, F., Emmanuel, I., Winfield, D. & Malia, R. (1974) Essential thrombocythaemia and peripheral gangrene. British Medical Journal, iii, 548-552.
18. Preston, F., Martin, J., Stewart, R. & Davies-Jones, G. (1979) Thrombocytosis, circulating platelet aggregates, and neurological dysfunction. British Medical Journal, ii, 1561-1563.
19. Rocca, R., Ciabattoni, C., Tartaglione, R., Cortelazzo, S., Barbui, T., Patrono, C. & Landolfi, R. (1995) Increased thromboxane biosynthesis in essential thrombocythaemia. Thrombosis and Haemostasis, 74, 1225-1230.
20. Schafer, A. (1984) Bleeding and thrombosis in the myeloproliferative disorders. Blood, 64, 1-12.
21. Schafer, A. (1991) Essential thrombocythemia. Progress in Thrombosis and Hemostasis, 10, 69-96.
22. Scheffer, M., Michiels, J., Simoons, M. & Roelandt, J. (1991) Thrombocythemia and coronary heart disease. American Heart Journal, 122, 573-576.
23. Tartaglia, A., Goldberg, J., Berk, P. & Wasserman, L. (1986) Adverse effects of antiaggregating platelet therapy in the treatment of polycythemia vera. Seminars in Hematology, 23, 172-176.
24. Van Genderen, P. & Michiels, J. (1993) Primary thrombocythemia: diagnosis, clinical manifestations and management. Annals of Hematology, 67, 57-62.
25. Van Genderen, P. & Michiels, J. (1994) Erythromelalgic, thrombotic and haemorrhagic manifestations of thrombocythaemia. Presse Medicale, 23, 73-77.
26. Vreeken, J. & van Aken, W. (1971) Spontaneous aggregation of blood platelets as a cause of idiopathic thrombosis and recurrent painful toes and fingers. Lancet, ii, 1394-1397.
27. Weinfeld, A., Swolin, B. & Westin, J. (1994) Acute leukaemia after hydroxyurea therapy in polycythaemia vera and allied disorders: prospective study of efficacy and leukaemogenicity with therapeutic implications. European Journal of Haematology, 52, 134-139.