Suppression of tumor recurrence and metastasis by a combination of the PHSCN sequence and the antiangiogenic compound tetrathiomolybdate in prostate carcinoma

Neoplasia

Volumn 4, Issue 5, 2002, Pages 373-379

  Van Golen, Kenneth L ^a,b   Bao, Liwei ^a   Brewer, George J ^b   Pienta, Kenneth J ^a,b   Kamradt, Jeffrey M ^a   Livant, Donna L ^b   Merajver, Sofia D ^a  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Metastasis; PHSCN; Prostate carcinoma; Tetrathiomolybdate; Tumor recurrence

Indexed keywords

ANTINEOPLASTIC AGENT; COPPER; FIBRONECTIN; PROLYLHISTIDYLSERYLCYSTEINYLASPARAGINAMIDE; TETRATHIOMOLYBDIC ACID; UNCLASSIFIED DRUG; ACETYL PROLYL HISTIDYL SERYL CYSTEINYL ASPARAGINAMIDE; ACETYL-PROLYL-HISTIDYL-SERYL-CYSTEINYL-ASPARAGINAMIDE; ANGIOGENESIS INHIBITOR; MOLYBDENUM; OLIGOPEPTIDE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CANCER INHIBITION; CANCER PREVENTION; CANCER SIZE; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; COPPER DEFICIENCY; DRUG EFFICACY; DRUG MECHANISM; DRUG TOLERABILITY; HUMAN; HUMAN CELL; MALE; METASTASIS; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROSTATE CARCINOMA; RECURRENT CANCER; TREATMENT OUTCOME; TUMOR VASCULARIZATION; ADENOCARCINOMA; ANIMAL; CANCER TRANSPLANTATION; CELL CULTURE; COMPARATIVE STUDY; DISEASE MODEL; DRUG COMBINATION; LUNG TUMOR; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PROSTATE TUMOR; RAT; TUMOR RECURRENCE; VASCULARIZATION;

ADENOCARCINOMA; ANGIOGENESIS INHIBITORS; ANIMALS; COPPER; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; MOLYBDENUM; NEOPLASM RECURRENCE, LOCAL; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; OLIGOPEPTIDES; PROSTATIC NEOPLASMS; RATS; TUMOR CELLS, CULTURED;

EID: 0036708501     PISSN: 15228002     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.neo.7900258     Document Type: Article

References (17)

1. Contemporary update of prostate cancer staging nomograms (Partin Tables) for the new millennium
2. Chemotherapy for hormone refractory prostate cancer
3. Anti-invasive, antitumorigenic, and antimetastatic activities of the PHSCN sequence in prostate carcinoma
4. Invasion of selectively permeable sea urchin embryo basement membranes by metastatic tumor cells, but not by their normal counterparts
5. Physiology of fibronectin
6. Predominance of the metastatic phenotype in hybrids formed by fusion of mouse and human melanoma clones
7. Characterization of integrin subunits, cellular adhesion and tumorigenicity of four human prostate cell lines
8. Expression of cellular adhesion molecules on human prostate tumor cell lines
9. Downregulation of the beta4 integrin subunit in prostatic carcinoma and prostatic intraepithelial neoplasia
10. Prostatic carcinoma cell migration via alpha(v)beta3 integrin is modulated by a focal adhesion kinase pathway
11. RGD-recognizing integrins mediate interactions of human prostate carcinoma cells with endothelial cells in vitro
12. Human prostate carcinoma cells express functional alphallb(beta)3 integrin
13. Prostate-specific antigen, a serine protease, facilitates human prostate cancer cell invasion
14. Hepatocyte growth factor and invasion-stimulatory activity are induced in pleural fluid by surgery in lung cancer patients
15. Increased serum levels of soluble tumor necrosis factor a-receptors in patients undergoing partial liver resection
16. Over-expression of vascular endothelial growth factor after preoperative radiation therapy for rectal cancer