Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist

Molecular Pharmacology

Volumn 63, Issue 6, 2003, Pages 1281-1288

  Burbridge, Mike F ^a   Venot, Virginie ^a   Casara, Patrick J ^a   Perron Sierra, Françoise ^a   Hickman, John A ^a   Tucker, Gordon C ^a  

^a INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; [7 [[4 (PYRIDIN 2 YLAMINO)BUTYRYLAMINO]METHYL] 6,9 DIHYDRO 5H BENZOCYCLOHEPTEN 5 YL]ACETIC ACID; ANTINEOPLASTIC AGENT; BETA1 INTEGRIN; CASPASE 8; CELL ADHESION MOLECULE; FOCAL ADHESION KINASE; INTEGRIN; INTEGRIN ANTAGONIST; PROTEIN BAK; PROTEIN KINASE B; S 34961; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL SURVIVAL; COLON CARCINOMA; CONCENTRATION RESPONSE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INCUBATION TIME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; CASPASE 8; CASPASE 9; CASPASES; CELL ADHESION; CELL SURVIVAL; COLONIC NEOPLASMS; CYCLOHEPTANES; ENZYME ACTIVATION; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HT29 CELLS; HUMANS; INTEGRIN ALPHA5; INTEGRINS; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; PYRIDINES;

EID: 0038441393     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.63.6.1281     Document Type: Article

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