Effects of genistein on angiotensin-converting enzyme in rats

Life Sciences

Volumn 79, Issue 9, 2006, Pages 828-837

  Xu, Yin Yan ^a   Yang, Cui ^a   Li, Sheng Nan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin converting enzyme; Aorta; Endothelial cell; Estrogen; Extracellular signal regulated kinase 1 2; Genistein; Tamoxifen

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DIPEPTIDYL CARBOXYPEPTIDASE; ESTROGEN RECEPTOR; GENISTEIN; HORMONE RECEPTOR BLOCKING AGENT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; TAMOXIFEN;

ANIMAL CELL; ANIMAL EXPERIMENT; AORTA; ARTERY ENDOTHELIUM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; IMMUNOFLUORESCENCE; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE LEVEL;

ANIMALS; AORTA, THORACIC; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ESTROGEN ANTAGONISTS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; FLUORESCENT ANTIBODY TECHNIQUE; GENISTEIN; PEPTIDYL-DIPEPTIDASE A; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SELECTIVE ESTROGEN RECEPTOR MODULATORS; TAMOXIFEN;

EID: 33745712201     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.02.035     Document Type: Article

References (52)

1. Adlercreutz H. Western diet and Western diseases: some hormonal and biochemical mechanisms and associations. Scandinavian Journal of Clinical and Laboratory Investigation 201 (1990) 3-23 (Supplementum)
2. Anderson J.J., Ambrose W.W., and Garner S.C. Biphasic effects of genistein on bone tissue in the ovariectomized, lactating rat model. Proceedings of the Society for Experimental Biology and Medicine vol. 217 (1998), Society for Experimental Biology and Medicine, New York, NY 345-350
3. Asmar R.G., Pannier B., Santoni J.P., Laurent S., London G.M., Levy B.I., and Safar M.E. Reversion of cardiac hypertrophy and reduced arterial compliance after converting enzyme inhibition in essential hypertension. Circulation 78 (1988) 941-950
4. Baker V.L., Leitman D., and Jaffe R.B. Selective estrogen receptor modulators in reproductive medicine and biology. Obstetrical and Gynecological Survey 55 7 Suppl. 2 (2000) S21-S47
5. Barkhem T., Carlsson B., Nilsson Y., Enmark E., Gustafsson J., and Nilsson S. Differential response of estrogen receptor α and estrogen receptor β to partial estrogen agonists/antagonists. Molecular Pharmacology 54 (1998) 105-112
6. Barnes S. Evolution of the health benefits of soy isoflavones. Proceedings of the Society for Experimental Biology and Medicine vol. 217 (1998), Society for Experimental Biology and Medicine, New York, NY 386-392
7. Bartholomew R.M., and Ryan D.S. Lack of mutagenicity of some phytoestrogens in the salmonella/mammalian microsome assay. Mutation Research 78 4 (1980) 317-321
8. Baudin B., Berard M., Carrier J.L., Legrand Y., and Drouet L. Vascular origin determines angiotensin I-converting enzyme expression in endothelial cells. Endothelium: Journal of Endothelial Cell Research 5 (1997) 73-84
9. Brosnihan K.B., Li P., and Ferrario C.M. Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide. Hypertension 27 (1996) 523-528
10. Chappell M.C., Pirro N.T., Sykes A., and Ferrario C.M. Metabolism of angiotensin-(1-7) by angiotensin-converting enzyme. Hypertension 31 (1998) 362-367
11. Chen X.W., Garner S.C., and Anderson J.J. Isoflavones regulate interleukin-6 and osteoprotegerin synthesis during osteoblast cell differentiation via an estrogen-receptor-dependent pathway. Biochemical and Biophysical Research Communications 295 (2002) 417-422
12. Cole O.F., Fan T.P., and Lewis G.P. Isolation, characterisation, growth and culture of endothelial cells from the rat aorta. Cell Biology International Reports 10 6 (1986) 399-405
13. Corvol P., Michaud A., Soubrier F., and Williams T. Recent advances in knowledge of the structure and function of the angiotensin I converting enzyme. Journal of Hypertension 13 suppl. 3 (1995) S3-S10
14. Dixon R.A., and Ferreira D. Genistein. Phytochemistry 60 3 (2002) 205-211
15. Duarte J., Ocete M.A., Perez-Vizcaino F., Zarzuelo A., and Tamargo J. Effect of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase. European Journal of Pharmacology 338 (1997) 25-33
16. Dubey R.K., Gillespie D.G., Imthurn B., Rosselii M., Jackson E., and Keller P. Phytoestrogens inhibit growth and MAP kinase activity in human aortic smooth muscle cells. Hypertension 33 (1999) 177-182
17. Dwyer J.T., Goldin B.R., Saul N., Gualtieri L., Barakat S., and Adlercreutz H. Tofu and soy drinks contain phytoestrogens. Journal of the American Dietetic Association 94 7 (1994) 739-743
18. Dzau V.J. Molecular biology of angiotensin II biosynthesis and receptors. Canadian Journal of Cardiology 11 (1995) 21F-26F
19. Gallagher P.E., Li P., Lenhart J.R., Chappell M.C., and Brosnihan K.B. Estrogen regulation of angiotensin-converting enzyme mRNA. Hypertension 33 1 Pt 2 (1999) 323-328
20. Gibbons G.H. The pathophysiology of hypertension: the importance of angiotensin II in cardiovascular remodeling. American Journal of Hypertension: Journal of the American Society of Hypertension 11 (1998) 177S-181S
21. Grady D., Wenger N.K., Herrington D., Khan S., Furberg C., Hunninghake D., Vittinghoff E., and Hulley S. Postmenopausal hormone therapy increases risk of venous thromboembolic disease: the heart and estrogen/progestin replacement study. Annals of Internal Medicine 132 (2000) 689-696
22. Groff J.L., Harp J.B., and DiGirolamo M. Simplified enzymatic assay of angiotensin-converting enzyme in serum. Clinical Chemistry 39 (1993) 400-404
23. Honore E.K., Williams J.K., Anthony M.S., and Clarkson T.B. Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques. Fertility and Sterility 67 (1997) 148-154
24. Jaspard E., Costerousse O., Wei L., Corvol P., and Alhenc-Gelas F. The angiotensin I-converting enzyme (kinase II): molecular and regulatory aspects. Agents and Actions Supplement 38 (1992) 349-358
25. Kelloff G.J., Crowell J.A., Hawk E.T., Steele V.E., Lubet R.A., Boone C.W., Covey J.M., Doody L.A., Omenn G.S., Greenwald P., Hong W.K., Parkinson D.R., Bagheri D., Baxter G.T., Blunden M., Doeltz M.K., Eisenhauer K.M., Johnson K., Knapp G.G., Longfellow D.G., Malone W.F., Nayfield S.G., Seifried H.E., Swall L.M., and Sigman C.C. Strategy and planning for chemopreventive drug development: clinical development plans II. Journal of Cellular Biochemistry. Supplement 26 (1996) 54-71
26. Klinge C.M., Blankenship K.A., Risinger K.E., Bhatnagar S., Noisin E.L., Sumanasekera W.K., Zhao L., Brey D.M., and Keynton R.S. Resveratrol and estradiol rapidly activate MAPK signaling through estrogen receptors alpha and beta in endothelial cells. The Journal of Biological Chemistry 280 9 (2005) 7460-7468
27. Lee B.S., Won J.W., Lee S.K., Choi Y., Yoon S., Park K.H., Cho D.J., and Song C.H. The effect of isoflavone on serum lipid profiles and bone markers in postmenopausal woman. Journal of the Korean Society of Menopause 8 (2002) 59-67
28. Lehoux S., and Tedgui A. Signal transduction of mechanical stresses in the vascular wall. Hypertension 32 (1998) 338-345
29. Li P., Chappell M.C., Ferrario C.M., and Brosnihan K.B. Angiotensin-(1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide. Hypertension 29 (1997) 394-400
30. Lichtenstein A. Soy protein, isoflavones and cardiovascular disease risk. The Journal of Nutrition 128 (1998) 1589-1592
31. Liu D., Homan L.L., and Dillon J.S. Genistein acutely stimulates nitric oxide synthesis in vascular endothelial cells by a cyclic adenosine 3′, 5′-monophosphate-dependent mechanism. Endocrinology 145 (2004) 5532-5539
32. Magee J.C., Stone A.E., Oldham K.T., and Guice K.S. Isolation, culture, and characterization of rat lung microvascular endothelial cells. The American Journal of Physiology 267 (1994) L433-L441
33. MerzDemlow B.E., Duncan A.M., Wangen K.E., Xu X., Carr T.P., Phipps W.R., and Kurzer M.S. Soy isoflavones improve plasma lipids in normocholesterolemic, premenopausal women. The American Journal of Clinical Nutrition 71 (2000) 1462-1469
34. Messina M.J., Persky V., Setchell K.D., and Barnes S. Soy intake and cancer risk: a review of the in vitro and in vivo data. Nutrition and Cancer 21 (1994) 113-131
35. Murkies A. Phytoestrogens-what is the current knowledge?. Australian Family Physician 27 Suppl 1 (1998) S47-S51
36. Nestel P.J., Pomeroy S.E., Sasahara T., Yamashita T., Liang Y.L., Dart A.M., Jennings G.L., Abbey M., and Cameron J.D. Arterial compliance in obese subjects is improved with dietary plant n-3 fatty acid from flaxseed oil despite increased LDL oxidizability. Arteriosclerosis, Thrombosis, and Vascular Biology 17 (1997) 1163-7110
37. Neutel J.M. Effect of the renin-angiotensin system on the vessel wall: using ACE inhibition to improve endothelial function. Journal of Human Hypertension 18 (2004) 599-606
38. Polkowski K., and Mazurek A.P. Biological properties of genistein. A review of in vitro and in vivo data. Acta Poloniae Pharmaceutica 57 (2000) 135-155
39. Potter S.M., Baum J.A., Teng H., Stillman R.J., Shay N.F., and Erdman Jr. J.W. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. The American Journal of Clinical Nutrition 68 (1998) 1375S-1379S
40. Satake N., and Shibata S. The potentiating effect of genistein on the relaxation induced by isoproterenol in rat aortic rings. General Pharmacology 33 (1999) 221-227
41. Scribner A.W., Loscalzo J., and Napoli C. The effect of angiotensin-converting enzyme inhibition on endothelial function and oxidant stress. European Journal of Pharmacology 482 (2003) 95-99
42. Setchell K.D. Phytoestrogens: the biochemistry, physiology and implications for human health of soy isoflavones. The American Journal of Clinical Nutrition 68 (1998) 1333S-1346S
43. Setchell K.D.R., and Cassidy A. Dietary isoflavones: biological effects and relevance to human health. The Journal of Nutrition 129 (1999) 758S-767S
44. Tominaga S. Cancer incidence in Japanese in Japan, Hawaii, and western United States. National Cancer Institute Monograph 69 (1985) 83-92
45. Villard E., and Soubrier F. Molecular biology and genetics of the angiotensin-I-converting enzyme: potential implications in cardiovascular diseases. Cardiovascular Research 32 (1996) 999-1007
46. Voigt L.F., Weiss N.S., Chu J., Daling J.R., McKnight B., and Van Belle G. Progestagen supplementation of exogenous oestrogens and risk of endometrial cancer. Lancet 338 (1991) 274-277
47. Walker H.A., Dean T.S., Sanders T.A., Jackson G., Ritter J.M., and Chowienczyk P.J. The phytoestrogen genistein produces acute nitric oxide-dependent dilation of human forearm vasculature with similar potency to 17β-estradiol. Circulation 103 (2001) 258-262
48. Welches W.R., Brosnihan K.B., and Ferrario C.M. A comparison of the properties and enzymatic activity of three angiotensin processing enzymes: angiotensin converting enzyme, prolyl endopeptidase, and neutral endopeptidase. Life Sciences 52 (1993) 1461-1480
49. Wesselman J.P., Dobrian A.D., Schriver S.D., and Prewitt R.L. Src tyrosine kinases and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases mediate pressure-induced c-fos expression in cannulated rat mesenteric small arteries. Hypertension 37 (2001) 955-960
50. Wong W.W., Smith E.O., Stuff J.E., Hachey D.L., Heird W.C., and Powell H.J. Cholesterol-lowering effect of soy protein in nomocholesterolemic and hypercholesterolemic men. The American Journal of Clinical Nutrition 68 (1988) 1385S-1389S
51. Yamakoshi J., Piskula M.K., Izumi T., Tobe K., Saito M., Kataoka S., Obata A., and Kikuchi M. Isoflavone aglycone-rich extract without soy protein attenuates atherosclerosis development in cholesterol-fed rabbits. The Journal of Nutrition 130 (2000) 1887-1893
52. Yamashita Y., Kawada S., and Nakano H. Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol. Biochemical Pharmacology 39 4 (1990) 737-744