How does cross-reactive stimulation affect the longevity of CD8+ T cell memory?

PLoS Computational Biology

Volumn 2, Issue 6, 2006, Pages 0508-0517

  Ganusov, Vitaly V ^a,c   Pilyugin, Sergei S ^b   Ahmed, Rafi ^a   Antia, Rustom ^a  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; MEMORY ARCHITECTURE; PATHOGENS; POPULATION STATISTICS;

CELL MEMORY; CELL POPULATIONS; IMMUNE RESPONSE; IMMUNOLOGICAL MEMORY; MEMORY CELL;

T-CELLS;

ARTICLE; CD8+ T LYMPHOCYTE; CROSS REACTION; HOMEOSTASIS; LONGEVITY; MATHEMATICAL MODEL; MEMORY CELL; PATHOGENESIS; ANIMAL; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; C57BL MOUSE; CELL LINEAGE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MOUSE; PHYSIOLOGY; STATISTICAL MODEL; THEORETICAL MODEL; VERTEBRATE;

VERTEBRATA;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL LINEAGE; IMMUNOLOGIC MEMORY; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MODELS, IMMUNOLOGICAL; MODELS, STATISTICAL; MODELS, THEORETICAL; VERTEBRATES;

EID: 33745611127     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.0020055     Document Type: Article

References (31)

1. Zinkernagel R (2002) On differences between immunity and immunological memory. Curr Opin Immunol 14: 523-536.
2. Ahmed R, Gray D (1996) Immunological memory and protective immunity: nderstanding their relation. Science 272: 54-60.
3. Welsh RM, Selin LK, Szomolanyi-Tsuda E (2004) Immunological memory to viral infections. Annu Rev Immunol 22: 711-743.
4. Antia R, Ganusov VV, Ahmed R (2005) The role of models in understanding CD8(+) T-cell memory. Nat Rev Immunol 5: 101-111.
5. Tough D, Sprent J (1994) Turnover of naive- and memory-phenotype T cells. J Exp Med 179: 1127-1135.
6. Tough D, Borrow P, Sprent J (1996) Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 272: 1947-1950.
7. Lau L, Jamieson B, Somasundaram T, Ahmed R (1994) Cytotoxic T-cell memory without antigen. Nature 369: 648-652.
8. Hou S, Hyland L, Ryan K, Portner A, Doherty P (1994) Virus-specific CD8+ T-cell memory determined by clonal burst size. Nature 369: 652-654.
9. Mullbacher A (1994) The long-term maintenance of cytotoxic T cell memory does not require persistence of antigen. J Exp Med 179:: 317-321.
10. Ahmed R (1996) Tickling memory T cells. Science 272: 1904.
11. Beverley P (1990) Is T-cell memory maintained by cross-reactive stimulation? Immunol Today 11: 203-205.
12. Selin L, Nahill S, Welsh R (1994) Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses. J Exp Med 179: 1933-1943.
13. Kim SK, Cornberg M, Wang XZ, Chen HD, Selin LK, et al. (2005) Private specificities of CD8 T cell responses control patterns of heterologous immunity. J Exp Med 201: 523-533.
14. Tanchot C, Rocha B (1995) The peripheral T cell repertoire: Independent homeostatic regulation of virgin and activated CD8+ T cell pools. Eur J Immunol 25: 2127-2136.
15. Freitas A, Rocha B (1993) Lymphocyte lifespans: Homeostasis, selection and competition. Immunol Today 14: 25-29.
16. Tanchot C, Rosado M, Agenes F, Freitas A, Rocha B (1997) Lymphocyte homeostasis. Sem Immunol 9: 331-337.
17. Antia R, Pilyugin S, Ahmed R (1998) Models of immune memory: On the role of cross-reactive stimulation, competition, and homeostasis in maintaining immune memory. Proc Natl Acad Sci U S A 95: 14926-14931.
18. Callard R, Stark J, Yates A (2003) Fratricide: A mechanism for T memory-cell homeostasis. Trends Immunol 24: 370-375.
19. Brehm M, Pinto A, Daniels K, Schneck J, Welsh R, et al. (2002) T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens. Nat Immunol 3: 627-634.
20. Brehm MA, Markees TG, Daniels KA, Greiner DL, Rossini AA (2003) Direct visualization of cross-reactive effector and memory allo-specific CD8 T cells generated in response to viral infections. J Immunol 170: 4077-4086.
21. Welsh R, Selin L (2002) No one is naive: The significance of heterologous T-cell immunity. Nat Rev Immunol 2: 417-426.
22. De St. Groth F, Webster RG (1966) Disquisitions of original antigenic sin. i. Evidence in man. J Exp Med 124: 331-345
23. De St. Groth F, Webster RG (1966) Disquisitions on original antigenic sin. ii. Proof in lower creatures. J Exp Med 124: 347-361
24. Klenerman P, Zinkernagel R (1998) Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes. Nature 394: 482-485.
25. Mason D (1998) A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today 19: 395-404.
26. Borghans J, Noest A, De Boer R (1999) How specific should immunological memory be? J Immunol 163: 569-575.
27. Selin L, Vergilis K, Welsh R, Nahill S (1996) Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterologous viral infections. J Exp Med 183: 2489-2499.
28. Selin L, Lin M, Kraemer K, Pardoll D, Schneck J, et al. (1999) Attrition of T cell memory: Selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses. Immunity 11: 733-742.
29. Murali-Krishna K, Altman J, Suresh M, Sourdive D, Zajac A, et al. (1998) Counting antigen-specific CD8+ T cells: A re-evaluation of bystander activation during viral infection. Immunity 8: 177-187.
30. Arstila T, Casrouge A, Baron V, Even J, Kanellopoulos J, et al. (1999) A direct estimate of the human alpha beta T cell receptor diversity. Science 286: 958-961.
31. Casrouge A, Beaudoing E, Dalle S, Pannetier C, Kanellopoulos J, et al. (2000) Size estimate of the alpha beta TCR repertoire of naive mouse splenocytes. J Immunol 164: 5782-5787.