Specific positive and negative effects of FLIP on cell survival in human prostate cancer

Carcinogenesis

Volumn 27, Issue 7, 2006, Pages 1349-1357

  Shimada, Keiji ^a   Nakamura, Mitsutoshi ^a   Matsuyoshi, Syuichi ^a   Ishida, Eiwa ^a   Konishi, Noboru ^a  

^a NARA MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BETA CATENIN; CYCLIN D1; FLICE INHIBITORY PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEASOME INHIBITOR; RAF PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INVASION; CARCINOGENESIS; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; METASTASIS POTENTIAL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UBIQUITINATION;

APOPTOSIS; BETA CATENIN; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CYCLIN D1; CYSTEINE PROTEINASE INHIBITORS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUPEPTINS; MALE; PROSTATIC NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-RAF; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 33745603200     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi380     Document Type: Article

References (37)

1. Irmler,M., Thome,M., Hahne,M. et al. (1997) Inhibition of death receptor signals by cellular FLIP. Nature, 388, 190-195.
2. Hu,S., Vincenz,C., Ni,J., Gentz,R. and Dixit,V.M. (1997) I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J. Biol. Chem.,, 272, 17255-17257.
3. Park,S.J., Kim,Y.Y., Ju,J.W., Han,B.G., Park,S.I. and Park,B.J. (2001) Alternative splicing variants of c-FLIP transduce the differential signal through the Raf or TRAF2 in TNF-induced cell proliferation. Biochem. Biophys. Res. Commun., 289, 1205-1210.
4. Kataoka,T., Budd,R.C., Holler,N. et al. (2000) The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. Curr. Biol., 10, 640-648.
5. Tai,T.S., Fang,L.W. and Lai,M.Z. (2004) c-FLICE inhibitory protein expression inhibits T-cell activation. Cell Death Differ., 11, 69-79.
6. Conticello,C., Pedini,F., Zeuner,A., Patti,M., Zerilli,M., Stassi,G., Messina,A., Peschle,C. and De Maria,R. (2004) IL-4 protects tumor cells from anti-CD95 and chemotherapeutic agents via up-regulation of antiapoptotic proteins. J. Immunol., 172, 5467-5477.
7. Engels,I.H., Stepczynska,A., Stroh,C. et al. (2000) Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis. Oncogene, 19, 4563-4573.
8. Voorhees,P.M., Dees,E.C., O'Neil,B. and Orlowski,R.Z. (2003) The proteasome as a target for cancer therapy. Clin. Cancer Res., 9, 6316-6325.
9. Zhang,H.G., Wang,J., Yang,X., Hsu,H.C. and Mountz,J.D. (2004) Regulation of apoptosis proteins in cancer cells by ubiquitin. Oncogene, 23, 2009-2015.
10. Orlowski,R.Z., Eswara,J.R., Lafond-Walker,A., Grever,M.R., Orlowski,M. and Dang,C.V. (1998) Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor. Cancer Res., 58, 4342-4348.
11. Fujita,J., Tsujinaka,T., Yano,M., Ebisui,C., Saito,H., Katsume,A., Akamatsu,K., Ohsugi,Y., Shiozaki,H. and Monden,M. (1996) Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinoma-bearing mice with modulation of lysosomal and ATP-ubiquitin-dependent proteolytic pathways. Int. J. Cancer, 68, 637-643.
12. Zhang,X., Jin,T.G., Yang,H. et al. (2004) Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer. Cancer Res., 64, 7086-7091.
13. Mullen,P., McPhillips,F., MacLeod,K. et al. (2004) Antisense oligonucleotide targeting of Raf-1: Importance of raf-1 mRNA expression levels and raf-1-dependent signaling in determining growth response in ovarian cancer. Clin. Cancer Res., 10, 2100-2108.
14. Sherr,C.J. and Roberts,J.M. (1999) CDK inhibitors: Positive and negative regulators of G1-phase progression. Genes Dev., 13, 1501-1512.
15. Salvat,C., Aquaviva,C., Jariel-Encontre,I., Ferrara,P., Pariat,M., Steff,A.M., Carillo,S. and Piechaczyk,M. (1999) Are there multiple proteolytic pathways contributing to c-Fos, c-Jun and p53 protein degradation in vivo? Mol. Biol. Rep., 26, 45-51.
16. Polakis,P. (1999) The oncogenic activation of beta-catenin. Curr. Opin. Genet. Dev., 9, 15-21.
17. Polakis,P. (2000) Wnt signaling and cancer. Genes Dev., 14, 1837-1851.
18. Levkowitz,G., Waterman,H., Zamir,E., Kam,Z., Oved,S., Langdon,W.Y., Beguinot,L., Geiger,B. and Yarden,Y. (1998) c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Genes Dev., 12, 3663-3674.
19. Thien,C.B. and Langdon,W.Y. (1998) c-Cbl: A regulator of T cell receptor-mediated signalling. Immunol. Cell Biol., 76, 473-482.
20. Shimada,K., Matsuyoshi,S., Nakamura,M., Ishida,E. and Konishi,N. (2005) Phosphorylation status of Fas-associated death domain-containing protein (FADD) is associated with prostate cancer progression. J. Pathol., 206, 423-432.
21. Shimada,K., Nakamura,M., Ishida,E., Kishi,M., Yonehara,S. and Konishi,N. (2002) Phosphorylation of Fas-associated death domain contributes to enhancement of etoposide-induced apoptosis in prostate cancer cells. Jpn. J. Cancer Res., 93, 1164-1174.
22. Shimada,K., Nakamura,M., Ishida,E., Kishi,M., Yonehara,S. and Konishi,N. (2003) c-Jun NH2-terminal kinase-dependent fas activation contributes to etoposide-induced apoptosis in p53-mutated prostate cancer cells. Prostate, 55, 265-280.
23. Shimada,K., Matsuyoshi,S., Nakamura,M., Ishida,E., Kishi,M. and Konishi,N. (2004) Phosphorylation of FADD is critical for sensitivity to anticancer drug-induced apoptosis. Carcinogenesis, 25, 1089-1097.
24. Shimada,K., Nakamura,M., Ishida,E., Kishi,M., Matsuyoshi,S. and Konishi,N. (2004) The molecular mechanism of sensitization to Fas-mediated apoptosis by 2-methoxyestradiol in PC3 prostate cancer cells. Mol. Carcinog., 39, 1-9.
25. Gowardhan,B., West,A.F., Robson,C.N. and Leung,H.Y. (2004) Adenovirus-mediated expression of a soluble fibroblast growth factor receptor inhibits in vitro growth of prostateDU145cells. Prostate, 61, 50-59.
26. Toyoshima,F., Moriguchi,T. and Nishida,E. (1997) Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/ SAPK and MKK6-p38 pathways independent of CPP32-like proteases. J. Cell Biol., 139, 1005-1015.
27. Konishi,N., Nakamura,M., Kishi,M., Nishimine,M., Ishida,E. and Shimada,K. (2002) Heterogeneous methylation and deletion patterns of the INK4a/ARF locus within prostate carcinomas. Am. J. Pathol., 160, 1207-1214.
28. Gleason,D.F. (1992) Histologic grading of prostate cancer: A perspective. Hum. Pathol., 23, 273-279.
29. Mathas,S., Lietz,A., Anagnostopoulos,I. et al. (2004) c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis. J. Exp. Med., 199, 1041-1052.
30. Mezzanzanica,D., Balladore,E., Turatti,F. et al. (2004) CD95-mediated apoptosis is impaired at receptor level by cellular FLICE-inhibitory protein (long form) in wild-type p53 human ovarian carcinoma. Clin. Cancer Res., 10, 5202-5214.
31. Kataoka,T. (2005) The caspase-8 modulator c-FLIP. Crit. Rev. Immunol., 25, 31-58.
32. Lan,M., Kojima,T., Osanai,M., Chiba,H. and Sawada,N. (2004) Oncogenic Raf-1 regulates epithelial to mesenchymal transition via distinct signal transduction pathways in an immortalized mouse hepatic cell line. Carcinogenesis, 25, 2385-2395.
33. Birkenkamp,K.U., Tuyt,L.M., Lummen,C., Wierenga,A.T., Kruijer,W. and Vellenga,E. (2000) The p38 MAP kinase inhibitor SB203580 enhances nuclear factor-kappa B transcriptional activity by a non-specific effect upon the ERK pathway. Br. J. Pharmacol., 131, 99-107.
34. Casanovas,O., Miro,F., Estanyol,J.M., Itarte,E., Agell,N. and Bachs,O. (2000) Osmotic stress regulates the stability of cyclin D1 in a p38SAPK2-dependent manner. J. Biol. Chem., 275, 35091-35097.
35. Casanovas,O., Jaumot,M., Paules,A.B., Agell,N. and Bachs,O. (2004) P38SAPK2 phosphorylates cyclin D3 at Thr-283 and targets it for proteasomal degradation. Oncogene, 23, 7537-7544.
36. Gilot,D., Serandour,A.L., Ilyin,G.P. et al. (2005) A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes. Carcinogenesis, 26, 2086-2094.
37. Naito,M., Katayama,R., Ishioka,T. et al. (2004) Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling. Mol. Cell Biol., 24, 8418-8427.