-
1
-
-
0028913550
-
A novel protein that interacts with the death domain of Fas/ APO1 containing a sequence motif related to the death domain
-
Boldin, M.P., E.E. Varfolomeev, Z. Pancer, I.L. Mett, J.H. Camonis, and D. Wallach. 1995. A novel protein that interacts with the death domain of Fas/ APO1 containing a sequence motif related to the death domain. J. Biol. Chem. 270:7795-7798.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7795-7798
-
-
Boldin, M.P.1
Varfolomeev, E.E.2
Pancer, Z.3
Mett, I.L.4
Camonis, J.H.5
Wallach, D.6
-
2
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease. in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin, M., T. Goncharov, Y. Goltsev, and D. Wallach. 1996. Involvement of MACH, a novel MORT1/FADD-interacting protease. in Fas/APO-1- and TNF receptor-induced cell death. Cell. 85:803-815.
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.1
Goncharov, T.2
Goltsev, Y.3
Wallach, D.4
-
3
-
-
0029753773
-
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation
-
Chen, Y.-R., X. Wang, D. Templeton, R.J. Davis, and T.-H. Tan. 1996. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation. J. Biol. Chem. 271:31929-31936.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31929-31936
-
-
Chen, Y.-R.1
Wang, X.2
Templeton, D.3
Davis, R.J.4
Tan, T.-H.5
-
4
-
-
0029026548
-
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
-
Chinnaiyan, A.M., K. O'Rourke, M. Tewari, and V.M. Dixit. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell. 81:505-512.
-
(1995)
Cell
, vol.81
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
5
-
-
0029965280
-
FADD/ MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
-
Chinnaiyan A.M., C.G. Tepper, M.F. Seldin, K. O'Rourke, F.C. Kischkel, S. Hellbardt, P.H. Krammer, M.E. Peter, and V.M. Dixit. 1996. FADD/ MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J. Biol. Chem. 271:4961-4965.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4961-4965
-
-
Chinnaiyan, A.M.1
Tepper, C.G.2
Seldin, M.F.3
O'Rourke, K.4
Kischkel, F.C.5
Hellbardt, S.6
Krammer, P.H.7
Peter, M.E.8
Dixit, V.M.9
-
6
-
-
0029959632
-
Specific cleavage of α-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1β-converting enzyme/Ced-3 protease distinct from the poly (ADP-ribose) polymerase protease
-
Cryns, V.L., L. Bergeron, H. Zhu, H. Li, and J. Yuan. 1996. Specific cleavage of α-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1β-converting enzyme/Ced-3 protease distinct from the poly (ADP-ribose) polymerase protease. J. Biol. Chem. 271:31277-31282
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31277-31282
-
-
Cryns, V.L.1
Bergeron, L.2
Zhu, H.3
Li, H.4
Yuan, J.5
-
7
-
-
0029782176
-
Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine- stimulated monocytes and epithelial cells
-
Cuenda, A., G. Alonso, N. Morrice, M. Jones, R. Meier, P. Cohen, and A.R. Nebreda. 1996. Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine- stimulated monocytes and epithelial cells. EMBO (Eur. Mol. Biol. Organ.) J. 15:4156-4164.
-
(1996)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.15
, pp. 4156-4164
-
-
Cuenda, A.1
Alonso, G.2
Morrice, N.3
Jones, M.4
Meier, R.5
Cohen, P.6
Nebreda, A.R.7
-
8
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphotylates the c-Jun activation domain
-
Derijard, B., M. Hibi, I.-H. Wu, T. Barrett, B. Su, T. Deng, M. Karin and R.J. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphotylates the c-Jun activation domain. Cell. 76:1025-1037.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.-H.3
Barrett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
9
-
-
0028935974
-
Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms
-
Derijard, B., J. Raingeaud, T. Barret, I.-H. Wu, J. Han, R.J. Ulevitch, and R.J. Davis. 1995. Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science. 267:682-685.
-
(1995)
Science
, vol.267
, pp. 682-685
-
-
Derijard, B.1
Raingeaud, J.2
Barret, T.3
Wu, I.-H.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
10
-
-
0030044324
-
ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis
-
Duan, H., A.M. Chinnaiyan, P.L. Hudson, J.P. Wing, W.W. He, and V.M. Dixit. 1996a. ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis. J. Biol. Chem. 271:1621-1625.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1621-1625
-
-
Duan, H.1
Chinnaiyan, A.M.2
Hudson, P.L.3
Wing, J.P.4
He, W.W.5
Dixit, V.M.6
-
11
-
-
0030008812
-
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B
-
Duan, H., K. Orth, A.M. Chinnaiyan, G.G. Poirier, C.J. Froelich, W.W. He, and V.M. Dixit. 1996b. ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B. J. Biol. Chem. 271:16720-16724.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16720-16724
-
-
Duan, H.1
Orth, K.2
Chinnaiyan, A.M.3
Poirier, G.G.4
Froelich, C.J.5
He, W.W.6
Dixit, V.M.7
-
13
-
-
0029022365
-
Involvement of an ICE-like protease in Fas-mediated apoptosis
-
Enari, M., H. Hug, and S. Nagata. 1995. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature. 375:78-81.
-
(1995)
Nature
, vol.375
, pp. 78-81
-
-
Enari, M.1
Hug, H.2
Nagata, S.3
-
14
-
-
0029978182
-
Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
-
Enari, M., R.V. Talanian, W.W. Wong, and S. Nagata. 1996. Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature. 380:723-726.
-
(1996)
Nature
, vol.380
, pp. 723-726
-
-
Enari, M.1
Talanian, R.V.2
Wong, W.W.3
Nagata, S.4
-
15
-
-
0029005646
-
A novel human protease similar to the interleukin-1β converting enzyme induces apoptosis in transfected cells
-
Faucheu, C., A. Diu, A.W.E. Chan, A.-M. Blanchet, C. Miossec, F. Herve, V. Colard-Dutilleu, Y. Gu, R.A. Aldape, J.A. Lippke et al. 1995. A novel human protease similar to the interleukin-1β converting enzyme induces apoptosis in transfected cells. EMBO (Eur. Mol. Biol. Organ.) J. 14:1914-1922.
-
(1995)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.14
, pp. 1914-1922
-
-
Faucheu, C.1
Diu, A.2
Chan, A.W.E.3
Blanchet, A.-M.4
Miossec, C.5
Herve, F.6
Colard-Dutilleu, V.7
Gu, Y.8
Aldape, R.A.9
Lippke, J.A.10
-
16
-
-
0027973061
-
CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegance cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme
-
Fernandes-Alnemri, T., G. Litwack, and E.S. Alnemri. 1994. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegance cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme. J. Biol. Chem. 269:30761-30764.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30761-30764
-
-
Fernandes-Alnemri, T.1
Litwack, G.2
Alnemri, E.S.3
-
17
-
-
0029025549
-
Mch2, a new member of the apoptotic ced-3/ICE cystein protease gene family
-
Fernandes-Alnemri, T., G. Litwack, and E. Alnemri. 1995a. Mch2, a new member of the apoptotic ced-3/ICE cystein protease gene family. Cancer Res. 55: 2737-2742.
-
(1995)
Cancer Res.
, vol.55
, pp. 2737-2742
-
-
Fernandes-Alnemri, T.1
Litwack, G.2
Alnemri, E.3
-
18
-
-
0028884167
-
Mch3, a novel human cysteine protease highly related to CPP32
-
Fernandes-Alnemri, T., A. Takahashi, R. Armstrong, J. Krebs, L. Fritz, K. Tomaselli, L. Wang, Z. Yu, C. Croce, G. Salveson et al. 1995b. Mch3, a novel human cysteine protease highly related to CPP32. Cancer Res. 55:6045-6052.
-
(1995)
Cancer Res.
, vol.55
, pp. 6045-6052
-
-
Fernandes-Alnemri, T.1
Takahashi, A.2
Armstrong, R.3
Krebs, J.4
Fritz, L.5
Tomaselli, K.6
Wang, L.7
Yu, Z.8
Croce, C.9
Salveson, G.10
-
19
-
-
0344053451
-
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
-
Fernandes-Alnemri, T., R.C. Armstrong, J. Krebs, S.M. Srinivasula, L. Wang, F. Bullrich, L.C. Fritz, J.A. Trapani, K.J. Tomaselli, G. Litwack, and E.S. Alnemri. 1996. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl. Acad. Sci. USA. 93:7464-7469.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7464-7469
-
-
Fernandes-Alnemri, T.1
Armstrong, R.C.2
Krebs, J.3
Srinivasula, S.M.4
Wang, L.5
Bullrich, F.6
Fritz, L.C.7
Trapani, J.A.8
Tomaselli, K.J.9
Litwack, G.10
Alnemri, E.S.11
-
20
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han, J., J.D. Lee, L. Bibbs, and R.J. Ulevitch. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science. 265:808-811.
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.D.2
Bibbs, L.3
Ulevitch, R.J.4
-
21
-
-
0030044182
-
Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
-
Han, J., J-D. Lee, Y. Jiang, Z. Li, L. Feng, and R.J. Ulevitch. 1996. Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J. Biol. Chem. 271:2886-2891.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2886-2891
-
-
Han, J.1
Lee, J.-D.2
Jiang, Y.3
Li, Z.4
Feng, L.5
Ulevitch, R.J.6
-
22
-
-
0028288277
-
C.elegans cell survival gene ced-9 encodes a functional homologue of the mammalian proto-oncogene bcl-2
-
Hengartner, M.O., and H.R. Horvitz. 1994. C.elegans cell survival gene ced-9 encodes a functional homologue of the mammalian proto-oncogene bcl-2. Cell. 76:665-676.
-
(1994)
Cell
, vol.76
, pp. 665-676
-
-
Hengartner, M.O.1
Horvitz, H.R.2
-
23
-
-
0026582702
-
Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
-
Hengartner, M.O., R.E. Ellis, and H.R. Horvitz. 1992. Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature. 356:494-499.
-
(1992)
Nature
, vol.356
, pp. 494-499
-
-
Hengartner, M.O.1
Ellis, R.E.2
Horvitz, H.R.3
-
24
-
-
0025916387
-
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediated apoptosis
-
Itoh, N., S. Yonehara, A. Ishii, M. Yonehara, S. Mizushima, M. Sameshima, A. Hase, Y. Seto, and S. Nagata. 1991. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediated apoptosis. Cell. 66:233-243.
-
(1991)
Cell
, vol.66
, pp. 233-243
-
-
Itoh, N.1
Yonehara, S.2
Ishii, A.3
Yonehara, M.4
Mizushima, S.5
Sameshima, M.6
Hase, A.7
Seto, Y.8
Nagata, S.9
-
25
-
-
0027281373
-
A novel protein domain required for apoptosis
-
Itoh, N., and S. Nagata. 1993. A novel protein domain required for apoptosis. J. Biol. Chem. 268:10932-10937.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10932-10937
-
-
Itoh, N.1
Nagata, S.2
-
26
-
-
0031015043
-
Fas activation of the p38 mitogen-activated protein kinase signaling pathway requires ICE/CED-3 family proteases
-
Juo, P., C.J. Kuo, S.E. Reynolds, R.F. Konz, J. Raingeaud, R.J. Davis, H.-P. Biemann, and J. Blenis. 1997. Fas activation of the p38 mitogen-activated protein kinase signaling pathway requires ICE/CED-3 family proteases. Mol. Cell. Biol. 17:24-35.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 24-35
-
-
Juo, P.1
Kuo, C.J.2
Reynolds, S.E.3
Konz, R.F.4
Raingeaud, J.5
Davis, R.J.6
Biemann, H.-P.7
Blenis, J.8
-
27
-
-
0029078965
-
Identification and characterization of ICH-2, a novel member of the inlerleukin-1β-converting enzyme family of cysteine proteases
-
Kamens, J., M. Paskind, M. Hugunin, R.V. Talanian, H. Allen, D. Banach, N. Bump, M. Hackett, C.G. Johnston, P. Li et al. 1995. Identification and characterization of ICH-2, a novel member of the inlerleukin-1β-converting enzyme family of cysteine proteases. J. Biol. Chem. 270:15250-15256.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15250-15256
-
-
Kamens, J.1
Paskind, M.2
Hugunin, M.3
Talanian, R.V.4
Allen, H.5
Banach, D.6
Bump, N.7
Hackett, M.8
Johnston, C.G.9
Li, P.10
-
28
-
-
0027990778
-
Induction of apoptosis hy the Nedd2 gene, which encodes a protein similar to the Caenorhabditis elegance cell death gene ced-3 and the mammalian IL-1β-converting enzyme
-
Kumar, S., M. Kinoshita, M. Noda, N. Copeland, and N. Jenkins. 1994. Induction of apoptosis hy the Nedd2 gene, which encodes a protein similar to the Caenorhabditis elegance cell death gene ced-3 and the mammalian IL-1β-converting enzyme. Genes Dev. 8:1613-1626.
-
(1994)
Genes Dev.
, vol.8
, pp. 1613-1626
-
-
Kumar, S.1
Kinoshita, M.2
Noda, M.3
Copeland, N.4
Jenkins, N.5
-
29
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
Kyriakis, J.M., P. Banerjee, E. Nikolakaki, T. Dai, E.A. Rubie, M.F. Ahmad, J. Avruch, and J.R. Woodgett. 1994. The stress-activated protein kinase subfamily of c-Jun kinases. Nature. 369:156-160.
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
Dai, T.4
Rubie, E.A.5
Ahmad, M.F.6
Avruch, J.7
Woodgett, J.R.8
-
30
-
-
0030038488
-
Fas ligation induced apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells
-
Latinis, K.M., and G.A. Koretzky. 1996. Fas ligation induced apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. Blood. 87:871-875.
-
(1996)
Blood
, vol.87
, pp. 871-875
-
-
Latinis, K.M.1
Koretzky, G.A.2
-
31
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee, J.C., J.T. Laydon, P.C. McDonnell, T.F. Gallagher, S. Kumar, D. Green. D. McNulty, M.J. Blumenthal, J.R. Heys, S.W. Landvatter et al. 1994. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature. 372:739-746.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
32
-
-
0031016440
-
Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis
-
Lenczowski, J.M., L. Dominguez, A.M. Eder, L.B. King, C.M. Zacharchuk, and J.D. Ashwell. 1997. Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis. Mol. Cell. Biol. 17:170-181.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 170-181
-
-
Lenczowski, J.M.1
Dominguez, L.2
Eder, A.M.3
King, L.B.4
Zacharchuk, C.M.5
Ashwell, J.D.6
-
33
-
-
0030044012
-
Identification and characterization of CPP32/Mch-2 homolog 1, a novel cysteine protease similar to CPP32
-
Lippke, J.A., Y. Gu, C. Samecki, P.R. Caron, and M.S.-S. Su. 1996. Identification and characterization of CPP32/Mch-2 homolog 1, a novel cysteine protease similar to CPP32. J. Biol. Chem. 271:1825-1828.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1825-1828
-
-
Lippke, J.A.1
Gu, Y.2
Samecki, C.3
Caron, P.R.4
Su, M.S.-S.5
-
34
-
-
0029005805
-
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis
-
Los, M., M.V. Craen, L.C. Penning, H. Schenk, M. Weatendorp, P.A. Baeuerle. W. Droge, P.M. Krammer, W. Fiers, and K. Schulze-Osthoff. 1995. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature. 375:81-83.
-
(1995)
Nature
, vol.375
, pp. 81-83
-
-
Los, M.1
Craen, M.V.2
Penning, L.C.3
Schenk, H.4
Weatendorp, M.5
Baeuerle, P.A.6
Droge, W.7
Krammer, P.M.8
Fiers, W.9
Schulze-Osthoff, K.10
-
35
-
-
0029802815
-
Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity
-
Martin, S.J., D.M. Finucane, G.P. Amarante-Mendes, G.A. O'Brien, and D.R. Green. 1996. Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity. J. Biol. Chem. 271:28753-28756.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28753-28756
-
-
Martin, S.J.1
Finucane, D.M.2
Amarante-Mendes, G.P.3
O'Brien, G.A.4
Green, D.R.5
-
36
-
-
0029610432
-
Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis
-
Mashima, T., M. Naito, N. Fujita, K. Noguchi, and T. Tsuruo. 1995. Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis. Biochem. Biophys. Res. Commun. 271:1185-1192.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.271
, pp. 1185-1192
-
-
Mashima, T.1
Naito, M.2
Fujita, N.3
Noguchi, K.4
Tsuruo, T.5
-
37
-
-
0031033274
-
Inhibition of Ced-3/ICE-related protease does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak
-
McCarthy, N.J., M.K.B. Whyte, C.S. Gilbert, and G.I. Evan. 1997. Inhibition of Ced-3/ICE-related protease does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J. Cell Biol. 136:215-227.
-
(1997)
J. Cell Biol.
, vol.136
, pp. 215-227
-
-
McCarthy, N.J.1
Whyte, M.K.B.2
Gilbert, C.S.3
Evan, G.I.4
-
38
-
-
0029039180
-
Evidence for multiple activators for stress-activated protein kinases/c-Jun amino-terminal kinases
-
Moriguchi, T., H. Kawasaki, S. Matsuda, Y. Gotoh, and E. Nishida. 1995. Evidence for multiple activators for stress-activated protein kinases/c-Jun amino-terminal kinases. J. Biol. Chem. 270:12969-12972.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12969-12972
-
-
Moriguchi, T.1
Kawasaki, H.2
Matsuda, S.3
Gotoh, Y.4
Nishida, E.5
-
39
-
-
15844431960
-
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3
-
Moriguchi, T., N. Kuroyanagi, K. Yamaguchi, Y. Gotoh, K. Irie, T. Kano, K. Shirakabe, Y. Muro, H. Shibuya, K. Matsumoto et al. 1996a. A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. J. Biol. Chem. 271:13675-13679.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13675-13679
-
-
Moriguchi, T.1
Kuroyanagi, N.2
Yamaguchi, K.3
Gotoh, Y.4
Irie, K.5
Kano, T.6
Shirakabe, K.7
Muro, Y.8
Shibuya, H.9
Matsumoto, K.10
-
40
-
-
10244241798
-
2
-
2. J. Biol. Chem. 271:26981-26988.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26981-26988
-
-
Moriguchi, T.1
Toyoshima, F.2
Gotoh, Y.3
Iwamatsu, A.4
Irie, K.5
Mori, E.6
Kuroyanagi, N.7
Hagiwara, M.8
Matsumoto, K.9
Nishida, E.10
-
41
-
-
0030702895
-
A novel SAPK/JNK kinase, MKK7, stimulated by TNFα and cellular stresses
-
In press
-
Moriguchi, T., F. Toyoshima, N. Masuyama, H. Hanafusa, Y. Gotoh, and E. Nishida. 1997. A novel SAPK/JNK kinase, MKK7, stimulated by TNFα and cellular stresses. EMBO J. In press.
-
(1997)
EMBO J.
-
-
Moriguchi, T.1
Toyoshima, F.2
Masuyama, N.3
Hanafusa, H.4
Gotoh, Y.5
Nishida, E.6
-
42
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods. 65: 55-63.
-
(1983)
J. Immunol. Methods.
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
43
-
-
0029032878
-
Molecular cloning and pro-apoptotic activity of ICErel-II and ICErel-III, members of the ICE/ CED-3 family of cysteine proteases
-
Munday, N.A., J.P. Vaillancourt, A. Ali, F.J. Casano, D.K. Miller, S.M. Molineaux, T.T. Yamin, V.L. Yu, and D.W. Nicholson. 1995. Molecular cloning and pro-apoptotic activity of ICErel-II and ICErel-III, members of the ICE/ CED-3 family of cysteine proteases. J. Biol. Chem. 270:15870-15876.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15870-15876
-
-
Munday, N.A.1
Vaillancourt, J.P.2
Ali, A.3
Casano, F.J.4
Miller, D.K.5
Molineaux, S.M.6
Yamin, T.T.7
Yu, V.L.8
Nicholson, D.W.9
-
44
-
-
15844412409
-
FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex
-
Muzio, M., A. Chinnaiyan, F. Kischkel, K. O'Rourke, A. Shevchenko, J. Ni, C. Scaffidi, J. Bretz, M. Zhang, R. Gentz et al. 1996. FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/Apo-1) death-inducing signaling complex. Cell. 85:817-827.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.2
Kischkel, F.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.8
Zhang, M.9
Gentz, R.10
-
45
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3-like proteases necessary for mammalian apoptosis
-
Nicholson, D., A. Ali, N. Thornberry, J. Vaillancourt, C. Ding, M. Gallant, Y. Gareau, P. Griffin, M. Labele, Y. Lazebnik et al. 1995. Identification and inhibition of the ICE/CED-3-like proteases necessary for mammalian apoptosis. Nature. 375:37-43.
-
(1995)
Nature
, vol.375
, pp. 37-43
-
-
Nicholson, D.1
Ali, A.2
Thornberry, N.3
Vaillancourt, J.4
Ding, C.5
Gallant, M.6
Gareau, Y.7
Griffin, P.8
Labele, M.9
Lazebnik, Y.10
-
46
-
-
0030051528
-
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
-
Raingeaud, J., A.J. Whitmarsh, T. Barrett, B. Derijard, and R.J. Davis. 1996. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol. 16: 1247-1255.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1247-1255
-
-
Raingeaud, J.1
Whitmarsh, A.J.2
Barrett, T.3
Derijard, B.4
Davis, R.J.5
-
47
-
-
0028022750
-
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
-
Rouse, J., P. Cohen, S. Trigon, M. Morange, A. Alonso-Llamazares, D. Zamanillo, T. Hunt, and A.R. Nebreda. 1994. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell. 78:1027-1037.
-
(1994)
Cell
, vol.78
, pp. 1027-1037
-
-
Rouse, J.1
Cohen, P.2
Trigon, S.3
Morange, M.4
Alonso-Llamazares, A.5
Zamanillo, D.6
Hunt, T.7
Nebreda, A.R.8
-
48
-
-
0030918572
-
Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
-
Rudel, T., and G.M. Bokoch. 1997. Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science. 276:1571-1574.
-
(1997)
Science
, vol.276
, pp. 1571-1574
-
-
Rudel, T.1
Bokoch, G.M.2
-
49
-
-
0028558986
-
Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
-
Sanchez, I., R.T. Hughes, B.J. Mayer, K. Yee, J.R. Woodgett, J. Avruch, J.M. Kyriakis, and L.I. Zon. 1994. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature. 372:794-798.
-
(1994)
Nature
, vol.372
, pp. 794-798
-
-
Sanchez, I.1
Hughes, R.T.2
Mayer, B.J.3
Yee, K.4
Woodgett, J.R.5
Avruch, J.6
Kyriakis, J.M.7
Zon, L.I.8
-
50
-
-
0029670910
-
CPP32/Apopain is a key interleukin-1β converting enzyme-like protease involved in Fas-mediated apoptosis
-
Schlegel, J., I. Peters, S. Orrenius, D.K. Miller, N.C. Thornberry, T.T. Yamin, and D.W. Nicholson. 1996. CPP32/Apopain is a key interleukin-1β converting enzyme-like protease involved in Fas-mediated apoptosis. J. Biol. Chem. 271:1841-1844.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1841-1844
-
-
Schlegel, J.1
Peters, I.2
Orrenius, S.3
Miller, D.K.4
Thornberry, N.C.5
Yamin, T.T.6
Nicholson, D.W.7
-
51
-
-
0029861379
-
The Ced-3/interleukin-1β converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2α are substrates for the apoptotic mediator CPP32
-
Srinivasula, S.M., T. Fernandes-Alnemri, J. Zangrilli, N. Robertson, R.C. Armstrong, L. Wang, J.A. Trapani, K.J. Tomaselli, G. Litwack, and E.S. Alnemri. 1996. The Ced-3/interleukin-1β converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2α are substrates for the apoptotic mediator CPP32. J. Biol. Chem. 271:27099-27106.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27099-27106
-
-
Srinivasula, S.M.1
Fernandes-Alnemri, T.2
Zangrilli, J.3
Robertson, N.4
Armstrong, R.C.5
Wang, L.6
Trapani, J.A.7
Tomaselli, K.J.8
Litwack, G.9
Alnemri, E.S.10
-
52
-
-
0030006618
-
Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade
-
Stein, B., H. Brady, M.X. Yang, D.B. Young, and M.S. Barbosa. 1996. Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade. J. Biol. Chem. 271:11427-11433.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11427-11433
-
-
Stein, B.1
Brady, H.2
Yang, M.X.3
Young, D.B.4
Barbosa, M.S.5
-
53
-
-
0028990125
-
Yama/CPP32β, a mammalian homolog of CED-3 is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-Ribose)polymerase
-
Tewari, M., L. Quan, K. O'Rourke, S. Desnoyers, Z. Zeng, D. Beidler, G. Poirer, G. Salvesen, and V. Dixit. 1995. Yama/CPP32β, a mammalian homolog of CED-3 is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-Ribose)polymerase. Cell. 81:801-809.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.6
Poirer, G.7
Salvesen, G.8
Dixit, V.9
-
54
-
-
0347537940
-
Requirement for ceramide-mitiated SAPK/JNK signaling in stress-induced apoptosis
-
Verheij, M., R. Bose, X.H. Lin, B. Yao, W.D. Jarvis, S. Grant, M.J. Birrer, E. Szabo, L.I. Zon, J.M. Kyriakis et al. 1996. Requirement for ceramide-mitiated SAPK/JNK signaling in stress-induced apoptosis. Nature. 380:75-79.
-
(1996)
Nature
, vol.380
, pp. 75-79
-
-
Verheij, M.1
Bose, R.2
Lin, X.H.3
Yao, B.4
Jarvis, W.D.5
Grant, S.6
Birrer, M.J.7
Szabo, E.8
Zon, L.I.9
Kyriakis, J.M.10
-
55
-
-
0028978248
-
Purification of an interleukin-1β converting enzyme-related cystein protease that cleaves sterole regulatory element-binding proteins between the leucine zipper and transmembrane domains
-
Wang, X., J.T. Pai, E.A. Wiedenfeld, J.C. Medina, C.A. Slaughter, J.L. Goldstein, and M.S. Brown. 1995. Purification of an interleukin-1β converting enzyme-related cystein protease that cleaves sterole regulatory element-binding proteins between the leucine zipper and transmembrane domains. J. Biol. Chem. 270:18044-18050.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18044-18050
-
-
Wang, X.1
Pai, J.T.2
Wiedenfeld, E.A.3
Medina, J.C.4
Slaughter, C.A.5
Goldstein, J.L.6
Brown, M.S.7
-
56
-
-
0029934289
-
JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells
-
Wilson, D.J., K.A. Fortner, D.H. Lynch, R.R. Mattingly, I.G. Macara, J.A. Posada, and R.C. Budd. 1996. JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells. Eur. J. Immunol. 26:989-994.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 989-994
-
-
Wilson, D.J.1
Fortner, K.A.2
Lynch, D.H.3
Mattingly, R.R.4
Macara, I.G.5
Posada, J.A.6
Budd, R.C.7
-
57
-
-
0028880006
-
Opposing effect of ERK and JNK-p38 MAP kinase on apoptosis
-
Xia, Z., M. Dickens, J. Raingeaud, R.J. Davis, and M.E. Greenberg. 1995. Opposing effect of ERK and JNK-p38 MAP kinase on apoptosis. Science. 270: 1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
58
-
-
0024596722
-
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor
-
Yonehara, S., A. Ishii, and M. Yonehara. 1989. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J. Exp. Med. 169:1747-1756.
-
(1989)
J. Exp. Med.
, vol.169
, pp. 1747-1756
-
-
Yonehara, S.1
Ishii, A.2
Yonehara, M.3
-
59
-
-
0026448963
-
Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the periods of extensive programmed cell death
-
Yuan, J., and H.R. Horvitz. 1992. Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the periods of extensive programmed cell death. Development. 116:309-320.
-
(1992)
Development
, vol.116
, pp. 309-320
-
-
Yuan, J.1
Horvitz, H.R.2
-
60
-
-
0027525104
-
The C. elegance cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
-
Yuan, J., S. Shaham, S. Ledouw, H.M. Ellis, and H.R. Horvitz. 1993. The C. elegance cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell. 75:641-652.
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledouw, S.3
Ellis, H.M.4
Horvitz, H.R.5
-
61
-
-
0030294374
-
A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells
-
Zhang, C., Z. Ao, A. Seth, and S.F. Schlossman. 1996. A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells. J. Immunol. 157:3980-3987.
-
(1996)
J. Immunol.
, vol.157
, pp. 3980-3987
-
-
Zhang, C.1
Ao, Z.2
Seth, A.3
Schlossman, S.F.4
|