Inhibition of β-defensin gene expression in airway epithelial cells by low doses of residual oil fly ash is mediated by vanadium

Toxicological Sciences

Volumn 92, Issue 1, 2006, Pages 115-125

  Klein Patel, Marcia E ^a   Diamond, Gill ^b   Boniotto, Michelle ^a,c   Saad, Sherif ^a   Ryan, Lisa K ^a  

^a RUTGERS SCHOOL OF DENTAL MEDICINE   (United States)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Bovine; Defensins; Epithelial cells; Human; Innate immunity; Lung; Metals; Particulate matter; Residual oil fly ash; Vanadium

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BETA DEFENSIN 2; FERRIC SULFATE; INTERLEUKIN 1BETA; MESSENGER RNA; NICKEL SULFATE; SILICON DIOXIDE; TITANIUM DIOXIDE; TRACHEAL ANTIMICROBIAL PEPTIDE; UNCLASSIFIED DRUG; VANADIUM DERIVATIVE; VANADIUM PENTOXIDE; VANADYL SULFATE;

AIR QUALITY; AMBIENT AIR; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; COW; EPITHELIUM CELL; FLY ASH; GENE EXPRESSION REGULATION; HOST RESISTANCE; HUMAN; HUMAN CELL; IN VITRO STUDY; LEACHING; LUNG ALVEOLUS CELL TYPE 2; MORBIDITY; MORTALITY; NONHUMAN; PARTICULATE MATTER; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFECTION; RESPIRATORY TRACT INFLAMMATION; STIMULUS RESPONSE; TRACHEA MUCOSA;

BASE SEQUENCE; BETA-DEFENSINS; CARBON; CELL LINE; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; MASS SPECTROMETRY; PARTICULATE MATTER; PULMONARY ALVEOLI; TRACHEA; VANADIUM;

BOS TAURUS;

EID: 33745601078     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfj214     Document Type: Article

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