Epithelial Injury Induced by Exposure to Residual Oil Fly-Ash Particles: Role of Reactive Oxygen Species?

American Journal of Respiratory Cell and Molecular Biology

Volumn 17, Issue 5, 1997, Pages 625-633

  Dye, Janice A ^a   Adler, Kenneth B ^b   Richards, Judy H ^b   Dreher, Kevin L ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

OIL; REACTIVE OXYGEN METABOLITE;

AIR POLLUTION; ANIMAL; ARTICLE; CELL LINE; DRUG EFFECT; EPITHELIUM CELL; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; RAT; TRACHEA;

AIR POLLUTION; ANIMALS; CELL LINE; EPITHELIAL CELLS; INDUSTRIAL OILS; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; TRACHEA;

EID: 0031280280     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.17.5.2749     Document Type: Article

References (48)

1. Schwartz, J. 1994. Air pollution and daily mortality: a review and meta-analysis. Environ. Res. 64:36-52.
2. Pope, C. A., III, D. W. Dockery, and J. Schwartz. 1995. Review of epidemiological evidence of health effects of particulate air pollulion. Inhal. Toxicol. 7:1-18.
3. Dockery, D. W., and C. A. Pope, III. 1994. Acute respiratory effects of particulate air pollution. Annu. Rev. Public Health 15:107-132.
4. Schwartz, J., and R. Morris. 1995. Air pollution and hospital admissions for cardiovascular disease in Detroit, Michigan. Am. J. Epidemiol. 142:23-35.
5. Spengler, J. D., and G. D. Thurston. 1983. Mass and elemental composition of fine and course particles in six U.S. cities. Air Pollution Control Assoc. J. 33:1162-1171.
6. Kaartinen, L., P. Nettesheim, K. B. Adler, and S. H. Randell. 1993. Rat tracheal epithelial cell dilferenlation in vitro. In Vitro Cell. Dev. Biol. 29A:481-492.
7. Cohn, L. A., and K. B. Adler. 1992. Interactions between airway epithelium and mediators of inflammation. Exp. Lung Res. 18:299-322.
8. Hatch, G. E., E. Boykin, J. A. Graham, J. Lewtas, F. Pott, K. Loud, and J. L. Mumford. 1985. Inhalable particles and pulmonary host defense: in vivo and in vitro effects of ambient air and combustion particles. Environ. Res. 36:67-80.
9. Mustafa, M. G., A. D. Hacker, J. J. Ospital, M. Z. Hussain, and S. D. Lee. 1977. Biochemical effects of environmental oxidant pollutants in animal lungs. In Biochemical Effects of Environmental Pollutants. S. D. Lee, editor. Ann Arbor Science, Ann Arbor, MI, 59-96.
10. Jaskot, R. H., E. G. Challet, E. C. Grose, and M. A. Grady. 1983. An automated analysis of glutathione peroxidase, S-transferase, and reductase activity in animal tissue. J. Anal. Toxicol. 7:86-88.
11. Habig, W. H., M. J. Pabst, and W. B. Jakoby. 1974. Glutathione S-transferases: the first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249:7130-7139.
12. Anderson, M. E. 1985. Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol. 113:548-555.
13. Miller, N. J., C. Rice-Evans, M. J. Davies, V. Gophinathan, and A. Milner. 1993. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin. Sci. 84:407-412.
14. Gad, S. C., and C. S. Weil. 1995. Statistics for toxicologists. In Principles and Methods of Toxicology. A. W. Hayes, editor. Raven Press, New York, 221-274.
15. Anderson, M. E., and A. Meister. 1983. Transport and direct utilization of γ-glutamylcyst(e)ine for glutathione synthesis. Proc. Natl. Acad. Sci. USA 80:707-711.
16. Griffith, O. W., and A. Meister. 1979. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (s-n-butyl homocysteine sulfoximine). J. Biol. Chem. 254:7558-7560.
17. Deneke, S. M., and B. L. Fanburg. 1989. Regulation of cellular glutathione. Am. J. Physiol. 257 (Lung Cell. Mol. Physiol. 1):L163-L173.
18. Beckman, J. S., T. W. Beckman, J. Chen, P. A. Marshall, and B. A. Freeman. 1990. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA 87:1620-1624.
19. Dreher, K. L., R. H. Jaskot, J. R. Lehmann, J. H. Richards, J. K. McGee, A. J. Ghio, and D. L. Costa. 1997. Soluble transition metals mediate residual oil fly ash induced acute lung injury. J. Toxicol. Environ. Health 50:285-305.
20. Jaskot, R. H., D. L. Costa, U. P. Kodavanti, J. R. Lehmann, D. Winsett, and K. Dreher. 1995. Comparison of lung inflammation and airway reactivity in three strains of rats exposed to residual oil fly ash particles. Am. J. Respir. Crit. Care Med. 151:A264. (Abstr.)
21. Dreher, K., R. Jaskot, U. Kodavanti, J. Lehmann, D. Winsett, and D. Costa. 1996. Soluble transition metals mediate the acute pulmonary injury and airway hyperreactivity induced by residual oil fly ash particles. Chest 109 (Suppl. 3):33S-34S.
22. Pritchard, R. J., A. J. Ghio, J. R. Lehmann, D. W. Winsett, J. S. Tepper, P. Park, M. I. Gilmour, K. L. Dreher, and D. L. Costa. 1996. Oxidant generation and lung injury after particulate air pollutant exposure increase with the concentrations of associated metals. Inhal. Toxicol. 8:457-477.
23. Kodavanti, U. P., R. H. Jaskot, W.-Y. Su, D. L. Costa, A. J. Ghio, and K. L. Dreher. 1997. Genetic variability in combustion particle-induced chronic lung injury. Am. J. Physiol. 272 (Lung Cell Mol. Physiol. 16):L521-L532.
24. Schneeberger, E. E., and R. D. Lynch. 1992. Structure, function, and regulation of cellular tight junctions. Am. J. Physiol. 262 (Lung Cell. Mol. Physiol. 6):L647-L661.
25. Mercer, R. R., M. L. Russel, V. L. Roggli, and J. D. Crapo. 1994. Cell number and distribution in human and rat airways. Am. J. Respir. Cell Mol. Biol. 10:613-624.
26. Yeh, H. C., G. M. Schum, and M. T. Duggan. 1979. Anatomical models of the tracheobronchial and pulmonary regions of the rat. Anat. Rec. 195:483-492.
27. Schwartz, J. 1994. What are people dying of on high air pollution days? Environ. Res. 64:26-35.
28. Fox, R. B. 1984. Prevention of granulocyte-mediated oxidant lung injury in rats by a hydroxyl radical scavenger, dimethylthiourea. J. Clin. Invest. 74:1456-1464.
29. Parker, N. B., E. M. Berger, W. J. Curtis, M. E. Muldrow, S. L. Linas, and J. E. Repine. 1985. Hydrogen peroxide causes dimethylthiourea consumption while hydroxyl radical causes dimethylsulfoxide consumption in vitro. J. Free Radic. Biol. Med. 1:415-419.
30. Wasil, M., B. Halliwell, M. Grootveld, C. P. Moorhouse, D. C. S. Hutchison, and H. Baum. 1987. The specificity of thiourea, dimethylthiourea, and dimethylsulphoxide as scavengers of hydroxyl radicals. Biochem. J. 243: 867-870.
31. Kelner, M. J., R. Bagnell, and K. J. Welch. 1990. Thioureas react with superoxide radicals to yield a sulfhydryl compound. Explanation tor protective effect against paraquat. J. Biol. Chem. 265:1306-1311.
32. Rao, P. S., J. M. Luber, Jr., J. Millinowicz, P. Lalezar, and H. S. Mueller. 1988. Specificity of oxygen radical scavengers and assessment of free radical scavenger efficiency using luminol enhanced chemiluminescence. Biochem. Biophys. Res. Commun. 150:39-44.
33. Kinnula, V. L., J. R. Yankaskas, L. Chang, I. Virtanen, A. Linnala, B. H. Kang, and J. D. Crapo. 1994. Primary and immortalized (BEAS 2B) human bronchial epithelial cells have significant antioxidative capacity in vitro. Am. J. Respir. Cell Mol. Biol. 11:568-576.
34. Shi, X., N. S. Dalal, and V. Vallyathan. 1988. ESR evidence for the hydroxyl radical formation in aqueous suspension of quartz particles and its possible significance to lipid peroxidation in silicosis. J. Toxicol. Environ. Health 25:235-245.
35. Vallyathan, V., J. F. Mega, X. Shi, and N. S. Dalal. 1992. Enhanced generation of free radicals from phagocytes induced by mineral dusts. Am. J. Respir. Cell Mol. Biol. 6:404-413.
36. Schapira, R. M., A. J. Ghio, R. M. Effros, J. Morrisey, C. A. Dawson, and A. D. Hacker. 1994. Hydroxyl radicals are formed in the rat lung after asbestos instillation in vivo. Am. J. Respir. Cell Mol. Biol. 10:573-579.
37. Schapira, R. M., A. J. Ghio, R. M. Effros, J. Morrisey, U. A. Almagro, C. A. Dawson, and A. D. Hacker. 1995. Hydroxyl radical production and lung injury in the rat following silica or titanium dioxide instillation in vivo. Am. J. Respir. Cell Mol. Biol. 12:220-226.
38. Koppenol, W. H., J. J. Moreno, W. A. Pryor, H. Ischiropoulos, and J. S. Beckman. 1992. Peroxynitrite: a cloaked oxidant from superoxide and nitric oxide. Chem. Res. Toxicol. 5:834-842.
39. Till, G. O., L. S. Guilds, M. Mahrougui, H. P. Friedl, O. Trentz, and P. A. Ward. 1989. Role of xanthine oxidase in thermal injury of skin. Am. J. Pathol. 135:195-202.
40. 2 contributes to reperfusion injury of ischemic skeletal muscle. Am. J. Physiol. 258:H1415-H1419.
41. Meyer, M., H. L. Pahl, and P. A. Baeuerle. 1994. Regulation of transcription factors NF-κB and AP-1 by redox changes. Chem. Biol. Interact. 91:91-100.
42. Kaltschmidt, B., P. A. Baeuerle, and C. Kaltschmidt. 1993. Potential involvement of the transcription factor NF-κB in neurological disorders. Mol. Aspects Med. 14:171-190.
43. Marui, N., M. K. Offermann, R. Swerlick, C. Kunsch, C. A. Rosen, M. Ahmad, R. W. Alexander, and R. M. Medford. 1993. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J. Clin. Invest. 92:1866-1874.
44. Detterbeck, F. C., B. A. Keagy, E. J. Kron, and B. R. Wilcox. 1990. Oxygen free radical scavengers decrease reperfusion injury in lung transplantation. Ann. Thorac. Surg. 50:204-210.
45. Ikeda, Y., and D. M. Long. 1990. Comparative effects of direct and indirect hydroxyl radical scavengers on traumatic brain oedema. Acta Neurochir. Wien. 51(Suppl.):74-76.
46. Fairshter, R. D., N. D. Vasiri, L. C. Dearden, K. Malott, and M. Caserio. 1984. Effect of dimethylthiourea on paraquat toxicity in rats. Toxicol. Appl. Pharmacol. 74:150-154.
47. Lewis, C. P. L., D. Dinsdale, and B. Nemery. 1994. Potentiation of oxidant-induced toxicity in hamster lung slices by dimethylthiourea. Free Radic. Biol. Med. 16:561-569.
48. Andreoli, S. P., J. A. McAteer, and C. Mallett. 1990. Reactive oxygen molecule-mediated injury in endothelial and renal tubular epithelial cells in vitro. Kidney Int. 38:785-794.