Glutamate leakage from a compartmentalized intracellular metabolic pool and activation of the lipoxygenase pathway mediate oxidative astrocyte death by reversed glutamate transport

GLIA

Volumn 54, Issue 1, 2006, Pages 47-57

  Re, Diane B ^a   Nafia, Imane ^a   Melon, Christophe ^a   Shimamoto, Keiko ^b   Kerkerian Le Goff, Lydia ^a   Had Aissouni, Laurence ^a  

^a CNRS   (France)

^b SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

Author keywords

Astrocytes; Cell death; Glutamate metabolism; Glutamate transport; Ischemia

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; ASPARTIC ACID; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; GLUTATHIONE; LIPOXYGENASE; PYROGLUTAMIC ACID; PYRROLIDONE 2,4 CARBOXYLIC ACID; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ARTICLE; ASTROCYTE; CELL COMPARTMENTALIZATION; CELL DEATH; CELL METABOLISM; CELL SURVIVAL; CYTOTOXICITY; ENZYME ACTIVATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ASPARTIC ACID; ASTROCYTES; BRAIN; BRAIN ISCHEMIA; CELL COMPARTMENTATION; CELL DEATH; CELLS, CULTURED; CYTOPROTECTION; ENZYME ACTIVATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID TRANSPORTER 1; EXTRACELLULAR FLUID; GLUTAMIC ACID; INTRACELLULAR FLUID; LIPOXYGENASE; MICE; OXIDATIVE STRESS; RATS;

EID: 33745519494     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20353     Document Type: Article

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