N-terminal residues in Cx43 and Cx40 determine physiological properties of gap junction channels, but do not influence heteromeric assembly with each other or with Cx26

Journal of Cell Science

Volumn 119, Issue 11, 2006, Pages 2258-2268

  Gemel, Joanna ^a   Lin, Xianming ^b   Veenstra, Richard D ^b   Beyer, Eric C ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Channel gating; Connexins; Gap junctions; Heteromeric channels; Intercellular communication

Indexed keywords

AMINO ACID; CONNEXIN 26; CONNEXIN 40; CONNEXIN 43; GLYCINE; LUCIFER YELLOW; MUTANT PROTEIN; POLYAMINE; SERINE; SPERMINE; TRITON X 100;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC CURRENT; GAP JUNCTION; GENE MUTATION; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; OLIGOMERIZATION; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PURIFICATION; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS; WILD TYPE;

CELL LINE; CONNEXIN 43; CONNEXINS; GAP JUNCTIONS; HELA CELLS; HUMANS; IMMUNOBLOTTING; ION CHANNEL GATING; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; SPERMINE;

EID: 33745502336     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02953     Document Type: Article

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