Heteromeric connexons formed by the lens connexins, connexin43 and connexin56

European Journal of Cell Biology

Volumn 80, Issue 1, 2001, Pages 11-19

  Berthoud, Viviana M ^a   Montegna, Elisabeth A ^a   Atal, Namita ^b   Aithal, Naga H ^a   Brink, Peter R ^c   Beyer, Eric C ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

Double whole cell patch clamp; Gap junctions; Heteromeric connexons; Lens connexins; Sucrose gradient sedimentation

Indexed keywords

CELL MEMBRANE PROTEIN; CONNEXIN 43; CONNEXIN 56; GAP JUNCTION PROTEIN; NUCLEAR PROTEIN; SUCROSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL MEMBRANE; CELL NUCLEUS; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; EPITHELIUM CELL; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; KIDNEY CELL CULTURE; LENS EPITHELIUM; MEMBRANE CHANNEL; MEMBRANE POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT;

EID: 0035138572     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-9335-00132     Document Type: Article

References (46)

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3. The gap junction protein connexin56 is phosphorylated in both the intracellular loop and the carboxy terminal regions
4. Isoform composition of connexin channels determines selectivity among second messengers and uncharged molecules
5. Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissues
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13. Distinct behavior of connexin56 and connexin46 gap junctional channels can be predicted from the behavior of their hemi-gap-junctional channels
14. Gap junction formation during development of the mouse lens
15. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity
16. 3 connexin gene leads to proteolysis and cataractogenesis in mice
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21. Changes in connexin expression and distribution during chick lens development
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26. Connexin46 is retained as monomers in a trans-Golgi compartment of osteoblastic cells
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29. Cell to cell communication and pH in the frog lens
30. Phosphorylation shifts unitary conductance and modifies voltage dependent kinetics of human connexin43 gap junction channels
31. Expression of the gap junction protein connexin43 in embryonic chick lens: Molecular cloning, ultrastructural localization, and post-translational phosphorylation
32. Multisubunit assembly of an integral plasma membrane channel protein, gap junction connexin43, occurs after exit from the ER
33. Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines
34. Two homologous protein components of hepatic gap junctions
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36. Chick connexin56, a novel lens gap junction protein
37. 2 treatment with development
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39. 2-connexin (connexin-26) can form heteromeric hemichannels
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41. Connexin43 and connexin45 form gap junctions with different molecular permeabilities in osteoblastic cells
42. Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes
43. Mouse Cx50, a functional member of the connexin family of gap junction proteins, is the lens fiber protein MP70
44. Selective interactions among the multiple connexin proteins expressed in the vertebrate lens: The second extracellular domain is a determinant of compatibility between connexins
45. Targeted ablation of connexin50 in mice results in microphthalmia and zonular pulverulent cataracts
46. Molecular cloning of sheep connexin49 and its identity with MP70