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Volumn 6, Issue 2, 2006, Pages 179-191

Translating genomic biomarkers into clinically useful diagnostics

Author keywords

Genomic biomarker; Microarray; Proteomics

Indexed keywords

BIOLOGICAL MARKER; DNA; PROTEIN;

EID: 33745480519     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/14737159.6.2.179     Document Type: Review
Times cited : (51)

References (122)
  • 2
    • 19844366493 scopus 로고    scopus 로고
    • High sensitive C-reactive protein: A novel biochemical markers and its role in coronary artery disease
    • Mitra B, Panja M. High sensitive C-reactive protein: a novel biochemical markers and its role in coronary artery disease. J. Assoc. Physicians India 53, 25-32 (2005).
    • (2005) J. Assoc. Physicians India , vol.53 , pp. 25-32
    • Mitra, B.1    Panja, M.2
  • 3
    • 17044418563 scopus 로고    scopus 로고
    • Novel serologic markers of cardiovascular risk
    • Oliveira GH. Novel serologic markers of cardiovascular risk. Curr. Atheroscler. Rep. 7, 148-154 (2005).
    • (2005) Curr. Atheroscler. Rep. , vol.7 , pp. 148-154
    • Oliveira, G.H.1
  • 4
    • 0037381602 scopus 로고    scopus 로고
    • Use of plasma brain natriuretic peptide concentration to aid in the diagnosis of heart failure
    • Shapiro BP, Chen HH, Burnett JC Jr, Redfield MM. Use of plasma brain natriuretic peptide concentration to aid in the diagnosis of heart failure. Mayo Clin. Proc. 78, 481-486 (2003).
    • (2003) Mayo Clin. Proc. , vol.78 , pp. 481-486
    • Shapiro, B.P.1    Chen, H.H.2    Burnett Jr., J.C.3    Redfield, M.M.4
  • 5
    • 0141917517 scopus 로고    scopus 로고
    • Clinical applications of B-type natriuretic peptide (BNP) testing
    • Cowie MR, Jourdain P, Maisel A et al. Clinical applications of B-type natriuretic peptide (BNP) testing. Eur. Heart J. 24, 1710-1718 (2003).
    • (2003) Eur. Heart J. , vol.24 , pp. 1710-1718
    • Cowie, M.R.1    Jourdain, P.2    Maisel, A.3
  • 6
    • 23244449046 scopus 로고    scopus 로고
    • B-type natriuretic peptide as a biomarker beyond heart failure: Speculations and opportunities
    • McKie PM, Burnett JC Jr. B-type natriuretic peptide as a biomarker beyond heart failure: speculations and opportunities. Mayo Clin. Proc. 80, 1029-1036 (2005).
    • (2005) Mayo Clin. Proc. , vol.80 , pp. 1029-1036
    • McKie, P.M.1    Burnett Jr., J.C.2
  • 7
    • 20244378550 scopus 로고    scopus 로고
    • Molecular genetic tumor markers in non-small cell lung cancer
    • Oyama T, Osaki T, Baba T et al. Molecular genetic tumor markers in non-small cell lung cancer. Anticancer Res. 25, 1193-1196 (2005).
    • (2005) Anticancer Res. , vol.25 , pp. 1193-1196
    • Oyama, T.1    Osaki, T.2    Baba, T.3
  • 8
  • 9
    • 0036126045 scopus 로고    scopus 로고
    • Cyclin D1 amplification and p16 (MTS1/CDK4) deletion correlate with poor prognosis in head and neck tumors
    • Namazie A, Alavi S, Olapade OI et al. Cyclin D1 amplification and p16 (MTS1/CDK4) deletion correlate with poor prognosis in head and neck tumors. Laryngoscope 112, 472-481 (2002).
    • (2002) Laryngoscope , vol.112 , pp. 472-481
    • Namazie, A.1    Alavi, S.2    Olapade, O.I.3
  • 10
    • 20544445201 scopus 로고    scopus 로고
    • 9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor α gene alterations
    • Perrone F, Tamborini E, Dagrada GP et al. 9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor α gene alterations. Cancer 104, 159-169 (2005).
    • (2005) Cancer , vol.104 , pp. 159-169
    • Perrone, F.1    Tamborini, E.2    Dagrada, G.P.3
  • 11
    • 17144399192 scopus 로고    scopus 로고
    • Biallelic deletions in INK4 in cutaneous melanoma are common and associated with decreased survival
    • Grafstrom E, Egyhazi S, Ringborg U, Hansson J, Platz A. Biallelic deletions in INK4 in cutaneous melanoma are common and associated with decreased survival. Clin. Cancer Res. 11, 2991-2997 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , pp. 2991-2997
    • Grafstrom, E.1    Egyhazi, S.2    Ringborg, U.3    Hansson, J.4    Platz, A.5
  • 12
    • 1842535882 scopus 로고    scopus 로고
    • Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer
    • Mitelman F, Johansson B, Mertens F. Fusion genes and rearranged genes as a linear function of chromosome aberrations in cancer. Nature Genet. 36, 331-334 (2004).
    • (2004) Nature Genet. , vol.36 , pp. 331-334
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 13
    • 4844228261 scopus 로고    scopus 로고
    • Will the new cytogenetics replace the old cytogenetics?
    • Salman M, Jhanwar SC, Ostrer H. Will the new cytogenetics replace the old cytogenetics? Clin. Genet. 66, 265-275 (2004).
    • (2004) Clin. Genet. , vol.66 , pp. 265-275
    • Salman, M.1    Jhanwar, S.C.2    Ostrer, H.3
  • 14
    • 0036211011 scopus 로고    scopus 로고
    • Combined comparative genomic hybridization and genomic microarray for detection of gene amplifications in pulmonary artery intimal sarcomas and adrenocortical tumors
    • Zhao J, Roth J, Bode-Lesniewska B et al. Combined comparative genomic hybridization and genomic microarray for detection of gene amplifications in pulmonary artery intimal sarcomas and adrenocortical tumors. Genes Chromosomes Cancer 34, 48-57 (2002).
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 48-57
    • Zhao, J.1    Roth, J.2    Bode-Lesniewska, B.3
  • 15
    • 25444523242 scopus 로고    scopus 로고
    • Identification of four gene variants associated with myocardial infarction
    • Shiffman D, Ellis SG, Rowland CM et al. Identification of four gene variants associated with myocardial infarction. Am. J. Hum. Genet. 77, 596-605 (2005).
    • (2005) Am. J. Hum. Genet. , vol.77 , pp. 596-605
    • Shiffman, D.1    Ellis, S.G.2    Rowland, C.M.3
  • 16
    • 0344091561 scopus 로고    scopus 로고
    • Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans
    • Carlson CS, Eberle MA, Rieder MJ, Smith JD, Kruglyak L, Nickerson DA. Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans. Nature Genet. 33, 518-521 (2003). Defines the number of polymorphisms that need to be genotyped in order to perform a whole-genome association study based on the resequencing of 50 genes in 47 individuals from two populations (African-American and European).
    • (2003) Nature Genet. , vol.33 , pp. 518-521
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3    Smith, J.D.4    Kruglyak, L.5    Nickerson, D.A.6
  • 17
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • Gabriel SB, Schaffner SF, Nguyen H et al. The structure of haplotype blocks in the human genome. Science 296, 2225-2229 (2002). Landmark paper describing the partitioning of the human genome into haplotype blocks and the similarities and differences between European, Asian and African populations.
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1    Schaffner, S.F.2    Nguyen, H.3
  • 18
    • 19944429040 scopus 로고    scopus 로고
    • A single-nucleotide polymorphism tagging set for human drug metabolism and transport
    • Ahmadi KR, Weale ME, Xue ZY et al. A single-nucleotide polymorphism tagging set for human drug metabolism and transport. Nature Genet. 37, 84-89 (2005). Important paper defining a single nucleotide polymorphism tagging set for genes involved in drug metabolism and transport.
    • (2005) Nature Genet. , vol.37 , pp. 84-89
    • Ahmadi, K.R.1    Weale, M.E.2    Xue, Z.Y.3
  • 19
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • The International HapMap Consortium. A haplotype map of the human genome. Nature 437, 1299-1320 (2005).
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 20
    • 19944422061 scopus 로고    scopus 로고
    • A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
    • Paik S, Shak S, Tang G et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N. Eng. J. Med. 351, 2817-2826 (2004). Validates a multigene assay for prediction of breast cancer recurrence. This assay is now commercially available.
    • (2004) N. Eng. J. Med. , vol.351 , pp. 2817-2826
    • Paik, S.1    Shak, S.2    Tang, G.3
  • 21
    • 4243098848 scopus 로고    scopus 로고
    • Molecular testing and prediction of clinical outcome in heart transplantation: A prospective multicenter trial
    • Mehra MR, Kobashigawa J, Hunt S et al. Molecular testing and prediction of clinical outcome in heart transplantation: a prospective multicenter trial. J. Heart Lung Transplant. 23, S106 (2004).
    • (2004) J. Heart Lung Transplant. , vol.23
    • Mehra, M.R.1    Kobashigawa, J.2    Hunt, S.3
  • 22
    • 20544440169 scopus 로고    scopus 로고
    • Noninvasive molecular screening for acute cardiac rejection: A multicenter prospective clinical study
    • Eisen HJ, Deng M, Mehra M et al. Noninvasive molecular screening for acute cardiac rejection: a multicenter prospective clinical study. J. Heart Lung Transplant. 22, S74 (2003).
    • (2003) J. Heart Lung Transplant. , vol.22
    • Eisen, H.J.1    Deng, M.2    Mehra, M.3
  • 24
    • 22844440427 scopus 로고    scopus 로고
    • Identification of hundreds of conserved and nonconserved human microRNAs
    • Bentwich I, Avniel A, Karov Y et al. Identification of hundreds of conserved and nonconserved human microRNAs. Nature Genet. 37, 766-770 (2005). Provides a prediction of the number of microRNAs present in the human genome and highlights the significant role of these molecules.
    • (2005) Nature Genet. , vol.37 , pp. 766-770
    • Bentwich, I.1    Avniel, A.2    Karov, Y.3
  • 25
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska EA et al. MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (2005).
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 26
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He L, Thomson JM, Hemann MT et al. A microRNA polycistron as a potential human oncogene. Nature 435, 828-833 (2005).
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 27
    • 27244434788 scopus 로고    scopus 로고
    • A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • Calin GA, Ferracin M, Cimmino A et al. A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N. Engl. J. Med. 353(17), 1793-801 (2005).
    • (2005) N. Engl. J. Med. , vol.353 , Issue.17 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3
  • 28
    • 31344441137 scopus 로고    scopus 로고
    • A single-molecule method for the quantitation of microRNA gene expression
    • Neely LA, Patel S, Garver J et al. A single-molecule method for the quantitation of microRNA gene expression. Nature Methods 3(1), 41-6 (2006).
    • (2006) Nature Methods , vol.3 , Issue.1 , pp. 41-46
    • Neely, L.A.1    Patel, S.2    Garver, J.3
  • 29
    • 9244242523 scopus 로고    scopus 로고
    • Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis
    • Xu XL, Yu J, Zhang HY et al. Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J. Gastroenterol. 10, 3441-3454 (2004).
    • (2004) World J. Gastroenterol. , vol.10 , pp. 3441-3454
    • Xu, X.L.1    Yu, J.2    Zhang, H.Y.3
  • 30
    • 11844302899 scopus 로고    scopus 로고
    • Promoter methylation profiling of 30 genes in human malignant melanoma
    • Furuta J, Umebayashi Y, Miyamoto K et al. Promoter methylation profiling of 30 genes in human malignant melanoma. Cancer Sci. 95, 962-968 (2004).
    • (2004) Cancer Sci. , vol.95 , pp. 962-968
    • Furuta, J.1    Umebayashi, Y.2    Miyamoto, K.3
  • 31
    • 33746662311 scopus 로고    scopus 로고
    • Quantitative assessment of DNA methylation: Potential applications for disease diagnosis, classification, and prognosis in clinical settings
    • Brena RM, Huang TH, Plass C. Quantitative assessment of DNA methylation: potential applications for disease diagnosis, classification, and prognosis in clinical settings. J. Mol. Med.17, 1-13 (2006). Good review of DNA methylation biomarkers and technologies.
    • (2006) J. Mol. Med. , vol.17 , pp. 1-13
    • Brena, R.M.1    Huang, T.H.2    Plass, C.3
  • 32
    • 20044390368 scopus 로고    scopus 로고
    • DNA methylation profiling of the human major histocompatibility complex: A pilot study for the human epigenome project
    • Rakyan VK, Hildmann T, Novik KL et al. DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project. PLoS Biol. 2, e405 (2004).
    • (2004) PLoS Biol. , vol.2
    • Rakyan, V.K.1    Hildmann, T.2    Novik, K.L.3
  • 33
    • 4544250024 scopus 로고    scopus 로고
    • Gene-promoter hypermethylation as a biomarker in lung cancer
    • Belinsky SA. Gene-promoter hypermethylation as a biomarker in lung cancer. Nature Rev. Cancer 4, 707-717 (2004).
    • (2004) Nature Rev. Cancer , vol.4 , pp. 707-717
    • Belinsky, S.A.1
  • 34
    • 0036515416 scopus 로고    scopus 로고
    • Emerging molecular markers of cancer
    • Sidransky D. Emerging molecular markers of cancer. Nature Rev. Cancer 2, 210-219 (2002).
    • (2002) Nature Rev. Cancer , vol.2 , pp. 210-219
    • Sidransky, D.1
  • 35
    • 11344292695 scopus 로고    scopus 로고
    • Genomic and proteomic profiling for biomarkers and signature profiles of toxicity
    • Merrick BA, Bruno ME. Genomic and proteomic profiling for biomarkers and signature profiles of toxicity. Curr. Opin. Mol. Ther. 6, 600-607 (2004).
    • (2004) Curr. Opin. Mol. Ther. , vol.6 , pp. 600-607
    • Merrick, B.A.1    Bruno, M.E.2
  • 36
    • 13444280261 scopus 로고    scopus 로고
    • Protein microarrays as tools for functional proteomics
    • LaBaer J, Ramachandran N. Protein microarrays as tools for functional proteomics. Curr. Opin. Chem. Biol. 9, 14-19 (2005).
    • (2005) Curr. Opin. Chem. Biol. , vol.9 , pp. 14-19
    • LaBaer, J.1    Ramachandran, N.2
  • 37
    • 0037250740 scopus 로고    scopus 로고
    • Antibody microarray profiling of human prostate cancer sera: Antibody screening and identification of potential biomarkers
    • Miller JC, Zhou H, Kwekel J et al. Antibody microarray profiling of human prostate cancer sera: antibody screening and identification of potential biomarkers. Proteomics 3, 56-63 (2003).
    • (2003) Proteomics , vol.3 , pp. 56-63
    • Miller, J.C.1    Zhou, H.2    Kwekel, J.3
  • 38
    • 23744444911 scopus 로고    scopus 로고
    • Challenges facing the development and use of protein chips to analyze the phosphoproteome
    • Beernink HT, Nock S. Challenges facing the development and use of protein chips to analyze the phosphoproteome. Expert Rev. Proteomics 2, 487-497 (2005).
    • (2005) Expert Rev. Proteomics , vol.2 , pp. 487-497
    • Beernink, H.T.1    Nock, S.2
  • 39
    • 24644448880 scopus 로고    scopus 로고
    • Distilling cancer biomarkers from the serum peptidome: High technology reading of tea leaves or an insight to clinical systems biology?
    • Robbins RJ, Villanueva J, Tempst P. Distilling cancer biomarkers from the serum peptidome: high technology reading of tea leaves or an insight to clinical systems biology? J. Clin. Oncol. 23, 4835-4837 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , pp. 4835-4837
    • Robbins, R.J.1    Villanueva, J.2    Tempst, P.3
  • 41
    • 23944470664 scopus 로고    scopus 로고
    • Peptidomic analysis of human blood specimens: Comparison between plasma specimens and serum by differential peptide display
    • Tammen H, Schulte I, Hess R et al. Peptidomic analysis of human blood specimens: comparison between plasma specimens and serum by differential peptide display. Proteomics 5, 3414-3422 (2005).
    • (2005) Proteomics , vol.5 , pp. 3414-3422
    • Tammen, H.1    Schulte, I.2    Hess, R.3
  • 42
    • 0037116832 scopus 로고    scopus 로고
    • Use of proteomic patterns in serum to identify ovarian cancer
    • Petricoin EF, Ardekani AM, Hitt BA et al. Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359, 572-577 (2002). Important paper that describes the first use of a proteomic signature of ovarian cancer.
    • (2002) Lancet , vol.359 , pp. 572-577
    • Petricoin, E.F.1    Ardekani, A.M.2    Hitt, B.A.3
  • 43
    • 25144483466 scopus 로고    scopus 로고
    • Autoantibody signatures in prostate cancer
    • Wang X, Yu J, Sreekumar A et al. Autoantibody signatures in prostate cancer. N. Engl. J. Med. 353, 1224-1235 (2005).
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1224-1235
    • Wang, X.1    Yu, J.2    Sreekumar, A.3
  • 44
    • 26944471174 scopus 로고    scopus 로고
    • The next wave in metabolome analysis
    • Nielsen J, Oliver S. The next wave in metabolome analysis. Trends Biotechnol. 23, 544-546 (2005).
    • (2005) Trends Biotechnol. , vol.23 , pp. 544-546
    • Nielsen, J.1    Oliver, S.2
  • 45
    • 0043069547 scopus 로고    scopus 로고
    • Understanding 'global' systems biology: Metabonomics and the continuum of metabolism
    • Nicholson JK, Wilson ID. Understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nature Rev. Drug Discov. 2, 668-676 (2003). Good overview of the use of metabonomics to elucidate complex gene-environment interactions through a systems biology approach.
    • (2003) Nature Rev. Drug Discov. , vol.2 , pp. 668-676
    • Nicholson, J.K.1    Wilson, I.D.2
  • 46
    • 2642566238 scopus 로고    scopus 로고
    • Metabolomics - A new exciting field within the "omics" sciences
    • Dettmer K, Hammock BD. Metabolomics - a new exciting field within the "omics" sciences. Environ. Health Perspect. 112, A396-A397 (2004).
    • (2004) Environ. Health Perspect. , vol.112
    • Dettmer, K.1    Hammock, B.D.2
  • 47
    • 0036007687 scopus 로고    scopus 로고
    • Metabolomics - The link between genotypes and phenotypes
    • Fiehn O. Metabolomics - the link between genotypes and phenotypes. Plant Mol. Biol. 48, 155-171 (2002).
    • (2002) Plant Mol. Biol. , vol.48 , pp. 155-171
    • Fiehn, O.1
  • 48
    • 0142040405 scopus 로고    scopus 로고
    • Metabolomics in systems biology
    • Weckwerth W. Metabolomics in systems biology. Annu. Rev. Plant Biol. 54, 669-689 (2003).
    • (2003) Annu. Rev. Plant Biol. , vol.54 , pp. 669-689
    • Weckwerth, W.1
  • 50
    • 0036913503 scopus 로고    scopus 로고
    • Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using H-NMR-based metabonomics
    • Brindle JT, Antti H, Holmes E et al. Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using H-NMR-based metabonomics. Nature Med. 8, 1439-1445 (2002).
    • (2002) Nature Med. , vol.8 , pp. 1439-1445
    • Brindle, J.T.1    Antti, H.2    Holmes, E.3
  • 51
    • 28444480986 scopus 로고    scopus 로고
    • Metabonomic modeling of drug toxicity
    • Keun HC. Metabonomic modeling of drug toxicity. Pharmacol. Ther. 109(1-2), 92-106 (2005).
    • (2005) Pharmacol. Ther. , vol.109 , Issue.1-2 , pp. 92-106
    • Keun, H.C.1
  • 53
    • 25444432040 scopus 로고    scopus 로고
    • Diagnostic genome profiling in mental retardation
    • de Vries BB, Pfundt R, Leisink M et al. Diagnostic genome profiling in mental retardation. Am. J. Hum. Genet. 77, 606-616 (2005).
    • (2005) Am. J. Hum. Genet. , vol.77 , pp. 606-616
    • De Vries, B.B.1    Pfundt, R.2    Leisink, M.3
  • 54
    • 15444376392 scopus 로고    scopus 로고
    • Comparing the genetic changes detected in the primary and secondary tumor sites of ovarian cancer using comparative genomic hybridization
    • Fishman A, Shalom-Paz E, Fejgin M, Gaber E, Altaras M, Amiel A. Comparing the genetic changes detected in the primary and secondary tumor sites of ovarian cancer using comparative genomic hybridization. Int. J. Gynecol. Cancer 15, 261-266 (2005).
    • (2005) Int. J. Gynecol. Cancer , vol.15 , pp. 261-266
    • Fishman, A.1    Shalom-Paz, E.2    Fejgin, M.3    Gaber, E.4    Altaras, M.5    Amiel, A.6
  • 55
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286, 531-537 (1999). Landmark paper describing the use of gene expression patterns to classify cancer subtypes.
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3
  • 56
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, Perou C, Tibshirani R et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl Acad. Sci. USA 98, 10869-10874 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.2    Tibshirani, R.3
  • 57
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van 't Veer LJ, Dai H, van de Vijver MJ et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530-536 (2002).
    • (2002) Nature , vol.415 , pp. 530-536
    • Van't Veer, L.J.1    Dai, H.2    Van De Vijver, M.J.3
  • 58
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver MJ, He YD, van't Veer LJ et al. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 347, 1999-2009 (2002).
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1999-2009
    • Van De Vijver, M.J.1    He, Y.D.2    Van't Veer, L.J.3
  • 59
    • 4143067096 scopus 로고    scopus 로고
    • Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer
    • Zhang Z, Bast RC Jr, Yu Y et al. Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer. Cancer Res. 64, 5882-5890 (2004).
    • (2004) Cancer Res. , vol.64 , pp. 5882-5890
    • Zhang, Z.1    Bast Jr., R.C.2    Yu, Y.3
  • 61
    • 27144472560 scopus 로고    scopus 로고
    • A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility
    • Reich D, Patterson N, Jager PL et al. A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nature Genet. 37, 1113-1118 (2005). One of the first studies to demonstrate the benefits of whole-genome admixture scans to define loci for complex diseases.
    • (2005) Nature Genet. , vol.37 , pp. 1113-1118
    • Reich, D.1    Patterson, N.2    Jager, P.L.3
  • 62
    • 26444577151 scopus 로고    scopus 로고
    • Whole genome association study of rheumatoid arthritis using 27 039 microsatellites
    • Tamiya G, Shinya M, Imanishi T et al. Whole genome association study of rheumatoid arthritis using 27 039 microsatellites. Hum. Mol. Genet. 14, 2305-2321 (2005).
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 2305-2321
    • Tamiya, G.1    Shinya, M.2    Imanishi, T.3
  • 63
    • 20144388722 scopus 로고    scopus 로고
    • Genome-wide association study in esophageal cancer using GeneChip mapping 10K array
    • Hu N, Wang C, Hu Y et al. Genome-wide association study in esophageal cancer using GeneChip mapping 10K array. Cancer Res. 65, 2542-2546 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 2542-2546
    • Hu, N.1    Wang, C.2    Hu, Y.3
  • 64
    • 6044263660 scopus 로고    scopus 로고
    • Proteomic analysis of human acute leukemia cells: Insight into their classification
    • Cui JW, Wang J, He K et al. Proteomic analysis of human acute leukemia cells: insight into their classification. Clin. Cancer Res. 10, 6887-6896 (2004).
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6887-6896
    • Cui, J.W.1    Wang, J.2    He, K.3
  • 65
    • 16544370448 scopus 로고    scopus 로고
    • Surfaced-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) differentiation of serum protein profiles of BRCA-1 and sporadic breast cancer
    • Becker S, Cazares LH, Watson P et al. Surfaced-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) differentiation of serum protein profiles of BRCA-1 and sporadic breast cancer. Ann. Surg. Oncol. 11, 907-914 (2004).
    • (2004) Ann. Surg. Oncol. , vol.11 , pp. 907-914
    • Becker, S.1    Cazares, L.H.2    Watson, P.3
  • 66
    • 18544375333 scopus 로고    scopus 로고
    • MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
    • Armstrong SA, Staunton JE, Silverman LB et al. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nature Genet. 30, 41-47 (2002).
    • (2002) Nature Genet. , vol.30 , pp. 41-47
    • Armstrong, S.A.1    Staunton, J.E.2    Silverman, L.B.3
  • 67
    • 19044399684 scopus 로고    scopus 로고
    • Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling
    • Yeoh EJ, Ross ME, Shurtleff SA et al. Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell 1, 133-143 (2002).
    • (2002) Cancer Cell , vol.1 , pp. 133-143
    • Yeoh, E.J.1    Ross, M.E.2    Shurtleff, S.A.3
  • 68
    • 16544369516 scopus 로고    scopus 로고
    • Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia
    • Bullinger L, Dohner K, Bair E et al. Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N. Engl. J. Med. 350, 1605-1616 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1605-1616
    • Bullinger, L.1    Dohner, K.2    Bair, E.3
  • 69
    • 19644379067 scopus 로고    scopus 로고
    • Toxicogenomics in the pharmaceutical industry: Hollow promises or real benefit?
    • Luhe A, Suter L, Ruepp S, Singer T, Weiser T, Albertini S. Toxicogenomics in the pharmaceutical industry: hollow promises or real benefit? Mutat. Res. 575, 102-115 (2005).
    • (2005) Mutat. Res. , vol.575 , pp. 102-115
    • Luhe, A.1    Suter, L.2    Ruepp, S.3    Singer, T.4    Weiser, T.5    Albertini, S.6
  • 70
    • 26944487205 scopus 로고    scopus 로고
    • Large-scale databases in toxicogenomics
    • Salter AH. Large-scale databases in toxicogenomics. Pharmacogenomics 6, 749-754 (2005).
    • (2005) Pharmacogenomics , vol.6 , pp. 749-754
    • Salter, A.H.1
  • 71
    • 19444376971 scopus 로고    scopus 로고
    • Drug metabolism and variability among patients in drug response
    • Wilkinson GR. Drug metabolism and variability among patients in drug response. N. Engl. J. Med. 352, 2211-2221 (2005). Comprehensive review of role of cytochrome P450 enzymes and impact of genetic variation in drug metabolism and response.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2211-2221
    • Wilkinson, G.R.1
  • 72
    • 4344579337 scopus 로고    scopus 로고
    • Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy
    • Evans WE. Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy. Ther. Drug. Monit. 26, 186-191 (2004).
    • (2004) Ther. Drug. Monit. , vol.26 , pp. 186-191
    • Evans, W.E.1
  • 74
    • 0035313156 scopus 로고    scopus 로고
    • Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia
    • Chen JS, Coustan-Smith E, Suzuki T et al. Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia. Blood 97, 2115-2120 (2001).
    • (2001) Blood , vol.97 , pp. 2115-2120
    • Chen, J.S.1    Coustan-Smith, E.2    Suzuki, T.3
  • 75
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Eng. J. Med. 350, 2129-2139 (2004).
    • (2004) N. Eng. J. Med. , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 76
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Jänne PA, Lee JC et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304, 1497-1500 (2004).
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Jänne, P.A.2    Lee, J.C.3
  • 77
    • 3543054544 scopus 로고    scopus 로고
    • Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment
    • Holleman A, Cheok MH, den Boer ML et al. Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. N. Eng. J. Med. 351, 533-542 (2004).
    • (2004) N. Eng. J. Med. , vol.351 , pp. 533-542
    • Holleman, A.1    Cheok, M.H.2    Den Boer, M.L.3
  • 78
    • 1842483155 scopus 로고    scopus 로고
    • Nutritional genomics: The next frontier in the postgenomic era
    • Kaput J, Rodriguez RL. Nutritional genomics: the next frontier in the postgenomic era. Physiol. Genomics 16, 166-177 (2004).
    • (2004) Physiol. Genomics , vol.16 , pp. 166-177
    • Kaput, J.1    Rodriguez, R.L.2
  • 79
    • 0037304548 scopus 로고    scopus 로고
    • A short-term, high-fat diet upregulates lipid metabolism and gene expression in human skeletal muscle
    • Cameron-Smith D, Burke LM, Angus DJ et al. A short-term, high-fat diet upregulates lipid metabolism and gene expression in human skeletal muscle. Am. J. Clin. Nutr. 77, 313-318 (2003).
    • (2003) Am. J. Clin. Nutr. , vol.77 , pp. 313-318
    • Cameron-Smith, D.1    Burke, L.M.2    Angus, D.J.3
  • 80
    • 26444493132 scopus 로고    scopus 로고
    • Nutrigenomics and nutrigenetics: The emerging faces of nutrition
    • Mutch DM, Wahli W, Williamson G. Nutrigenomics and nutrigenetics: the emerging faces of nutrition. FASEB J. 19(12), 1602-16 (2005). Good review of the emerging field of nutrigenomics.
    • (2005) FASEB J. , vol.19 , Issue.12 , pp. 1602-1616
    • Mutch, D.M.1    Wahli, W.2    Williamson, G.3
  • 81
    • 32444450912 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase 677C>T polymorphism and gastric cancer susceptibility in Mexico
    • In Press
    • Lacasana-Navarro M, Galvan-Portillo M, Chen J et al. Methylenetetrahydrofolate reductase 677C>T polymorphism and gastric cancer susceptibility in Mexico. Eur. J. Cancer (2006) (In Press).
    • (2006) Eur. J. Cancer
    • Lacasana-Navarro, M.1    Galvan-Portillo, M.2    Chen, J.3
  • 82
    • 23644452635 scopus 로고    scopus 로고
    • Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer
    • Wang L, Miao X, Tan W et al. Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer. Clin. Gastroenterol. Hepatol. 3(8), 743-751 (2005).
    • (2005) Clin. Gastroenterol. Hepatol. , vol.3 , Issue.8 , pp. 743-751
    • Wang, L.1    Miao, X.2    Tan, W.3
  • 83
    • 30044433308 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer: A nested case-control study
    • Van Guelpen BR, Wiren SM, Bergh AR et al. Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer: a nested case-control study. Eur. J. Cancer Prev. 15(1), 46-50 (2006).
    • (2006) Eur. J. Cancer Prev. , vol.15 , Issue.1 , pp. 46-50
    • Van Guelpen, B.R.1    Wiren, S.M.2    Bergh, A.R.3
  • 84
    • 23944519853 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) variants and bladder cancer: A population-based case-control study
    • Karagas MR, Park S, Nelson HH et al. Methylenetetrahydrofolate reductase (MTHFR) variants and bladder cancer: a population-based case-control study. Int. J. Hyg. Environ. Health. 208(5), 321-327 (2005).
    • (2005) Int. J. Hyg. Environ. Health , vol.208 , Issue.5 , pp. 321-327
    • Karagas, M.R.1    Park, S.2    Nelson, H.H.3
  • 85
    • 0346966836 scopus 로고    scopus 로고
    • Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
    • Krajinovic M, Lamothe S, Labuda D et al. Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia. Blood 103(1), 252-257 (2004).
    • (2004) Blood , vol.103 , Issue.1 , pp. 252-257
    • Krajinovic, M.1    Lamothe, S.2    Labuda, D.3
  • 86
    • 18344396568 scopus 로고    scopus 로고
    • Minimum information about a microarray experiment (MIAME) - Toward standards for microarray data
    • Brazma A, Hemingway P, Quackenbush J et al. Minimum information about a microarray experiment (MIAME) - toward standards for microarray data. Nature Genet. 29, 365-371 (2001). Important paper that set standards for publication of microarray data.
    • (2001) Nature Genet. , vol.29 , pp. 365-371
    • Brazma, A.1    Hemingway, P.2    Quackenbush, J.3
  • 89
    • 0036975148 scopus 로고    scopus 로고
    • Pattern recognition techniques in microarray data analysis
    • Valafar F. Pattern recognition techniques in microarray data analysis. Ann. NY Acad. Sci. 980, 41-64 (2002).
    • (2002) Ann. NY Acad. Sci. , vol.980 , pp. 41-64
    • Valafar, F.1
  • 90
    • 0035949684 scopus 로고    scopus 로고
    • Predicting clinical status of human breast cancer by using gene expression profiles
    • West M, Blanchette C, Dressman H et al. Predicting clinical status of human breast cancer by using gene expression profiles. Proc. Natl Acad. Sci. USA 98, 11462-11467 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11462-11467
    • West, M.1    Blanchette, C.2    Dressman, H.3
  • 91
    • 0035992248 scopus 로고    scopus 로고
    • Empirical Bayes methods and false discovery rates for microarrays
    • Efron B, Tibshirani R. Empirical Bayes methods and false discovery rates for microarrays. Genet. Epidemiol. 23, 70-86 (2002).
    • (2002) Genet. Epidemiol. , vol.23 , pp. 70-86
    • Efron, B.1    Tibshirani, R.2
  • 92
    • 0036517472 scopus 로고    scopus 로고
    • A comprehensive review of genetic association studies
    • Hirschhorn JN, Lohmueller K, Byrne E, Hirschhorn K. A comprehensive review of genetic association studies. Genet. Med. 4, 45-61 (2002). Comprehensive analysis of genetic association studies, noting the importance of careful study design and validation.
    • (2002) Genet. Med. , vol.4 , pp. 45-61
    • Hirschhorn, J.N.1    Lohmueller, K.2    Byrne, E.3    Hirschhorn, K.4
  • 94
    • 1842559788 scopus 로고    scopus 로고
    • Reproducibility of SELDI-TOF protein patterns in serum: Comparing datasets from different experiments
    • Baggerly KA, Morris JS, Coombes KR. Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments. Bioinformatics 20, 777-785 (2004).
    • (2004) Bioinformatics , vol.20 , pp. 777-785
    • Baggerly, K.A.1    Morris, J.S.2    Coombes, K.R.3
  • 95
    • 12444326150 scopus 로고    scopus 로고
    • Gene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors
    • Pusztai L, Ayers M, Stec J et al. Gene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors. Clin. Cancer Res. 9, 2406-2415 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2406-2415
    • Pusztai, L.1    Ayers, M.2    Stec, J.3
  • 96
    • 27144459430 scopus 로고    scopus 로고
    • Gene expression profile associated with response to doxorubicin-based therapy in breast cancer
    • Koike Folgueira MA, Carraro DM, Brentani H et al. Gene expression profile associated with response to doxorubicin-based therapy in breast cancer. Clin. Cancer Res. 11, 7434-7443 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , pp. 7434-7443
    • Koike Folgueira, M.A.1    Carraro, D.M.2    Brentani, H.3
  • 97
    • 24644434436 scopus 로고    scopus 로고
    • Serum proteomic fingerprinting discriminates between clinical stages and predicts disease progression in melanoma patients
    • Mian S, Ugurel S, Parkinson E et al. Serum proteomic fingerprinting discriminates between clinical stages and predicts disease progression in melanoma patients. J. Clin. Oncol. 23, 5088-5093 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , pp. 5088-5093
    • Mian, S.1    Ugurel, S.2    Parkinson, E.3
  • 98
    • 27144489697 scopus 로고    scopus 로고
    • Rethinking clinical proteomics
    • Constans A. Rethinking clinical proteomics. The Scientist 19, 20-21 (2005).
    • (2005) The Scientist , vol.19 , pp. 20-21
    • Constans, A.1
  • 99
    • 20444366275 scopus 로고    scopus 로고
    • Validation of genomics-based prognostic tests in malignant pleural mesothelioma
    • Gordon GJ, Rockwell GN, Godfrey, PA et al. Validation of genomics-based prognostic tests in malignant pleural mesothelioma. Clin. Cancer Res. 11, 4406-4414 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , pp. 4406-4414
    • Gordon, G.J.1    Rockwell, G.N.2    Godfrey, P.A.3
  • 102
    • 0036948076 scopus 로고    scopus 로고
    • Racial differences in responses to drug treatment
    • Taylor JSW, Ellis GR. Racial differences in responses to drug treatment. Am. J. Cardiovasc. Drugs 2(6), 389-399 (2002).
    • (2002) Am. J. Cardiovasc. Drugs , vol.2 , Issue.6 , pp. 389-399
    • Taylor, J.S.W.1    Ellis, G.R.2
  • 103
    • 0043014561 scopus 로고    scopus 로고
    • A review and assessment of potential sources of ethnic differences in drug responsiveness
    • Bjornsson TD, Wagner JA, Donahue SR et al. A review and assessment of potential sources of ethnic differences in drug responsiveness. J. Clin. Pharmacol. 43, 943-967 (2003).
    • (2003) J. Clin. Pharmacol. , vol.43 , pp. 943-967
    • Bjornsson, T.D.1    Wagner, J.A.2    Donahue, S.R.3
  • 104
    • 21344456345 scopus 로고    scopus 로고
    • Going from genome to pill
    • Service RF. Going from genome to pill. Science 308, 1858-1860 (2005).
    • (2005) Science , vol.308 , pp. 1858-1860
    • Service, R.F.1
  • 105
    • 22844452700 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors
    • Huntjens DR, Danhof M, Della Pasqua OE. Pharmacokinetic-pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors. Rheumatology (Oxford) 44, 846-859 (2005).
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 846-859
    • Huntjens, D.R.1    Danhof, M.2    Della Pasqua, O.E.3
  • 106
    • 26044474872 scopus 로고    scopus 로고
    • Validation and quality control of protein microarray-based analytical methods
    • Kricka LJ, Master SR. Validation and quality control of protein microarray-based analytical methods. Methods Mol. Med. 114, 233-255 (2005).
    • (2005) Methods Mol. Med. , vol.114 , pp. 233-255
    • Kricka, L.J.1    Master, S.R.2
  • 107
    • 28544438480 scopus 로고    scopus 로고
    • Present and future of rapid and/or high-throughput methods for nucleic acid testing
    • Csako G. Present and future of rapid and/or high-throughput methods for nucleic acid testing. Clin. Chim. Acta 363(1-2), 6-31 (2005).
    • (2005) Clin. Chim. Acta , vol.363 , Issue.1-2 , pp. 6-31
    • Csako, G.1
  • 108
    • 20144366490 scopus 로고    scopus 로고
    • Validation of tissue microarray immunohistochemistry staining and interpretation in diffuse large B-cell lymphoma
    • Zu Y, Steinberg SM, Campo E et al. Validation of tissue microarray immunohistochemistry staining and interpretation in diffuse large B-cell lymphoma. Leuk. Lymphoma 46, 693-701 (2005).
    • (2005) Leuk. Lymphoma , vol.46 , pp. 693-701
    • Zu, Y.1    Steinberg, S.M.2    Campo, E.3
  • 110
    • 0036514921 scopus 로고    scopus 로고
    • Needs assessment study of genetics education for general practitioners in Australia
    • Metcalfe S, Hurworth R, Newstead J, Robins R. Needs assessment study of genetics education for general practitioners in Australia. Genet. Med. 4, 71-77 (2002).
    • (2002) Genet. Med. , vol.4 , pp. 71-77
    • Metcalfe, S.1    Hurworth, R.2    Newstead, J.3    Robins, R.4
  • 111
    • 0037333738 scopus 로고    scopus 로고
    • Education: Teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine
    • Gurwitz D, Weizman A, Rehavi M. Education: teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine. Trends Pharmacol. Sci. 24, 122-125 (2003).
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 122-125
    • Gurwitz, D.1    Weizman, A.2    Rehavi, M.3
  • 112
    • 3543052218 scopus 로고    scopus 로고
    • From pharmacogenetics to personalized medicine: A vital need for educating health professionals and the community
    • Frueh FW, Gurwitz D. From pharmacogenetics to personalized medicine: a vital need for educating health professionals and the community. Pharmacogenomics 5, 571-579 (2004).
    • (2004) Pharmacogenomics , vol.5 , pp. 571-579
    • Frueh, F.W.1    Gurwitz, D.2
  • 113
    • 0038715898 scopus 로고    scopus 로고
    • American Cancer Society Guidelines for breast cancer screening: Update 2003
    • Smith RA, Saslow D, Sawyer KA et al. American Cancer Society Guidelines for breast cancer screening: update 2003. CA Cancer J. Clin. 53, 141-169 (2003).
    • (2003) CA Cancer J. Clin. , vol.53 , pp. 141-169
    • Smith, R.A.1    Saslow, D.2    Sawyer, K.A.3
  • 114
    • 0000938023 scopus 로고    scopus 로고
    • Notice of Intent; Genetic Testing under the Clinical Laboratory Improvement Amendments
    • May 4
    • Notice of Intent; Genetic Testing Under the Clinical Laboratory Improvement Amendments. 65 Fed. Reg. 25928, May 4, (2000)
    • (2000) Fed. Reg. , vol.65 , pp. 25928
  • 116
  • 117
    • 11044228905 scopus 로고    scopus 로고
    • A systematic review of cost-effectiveness analyses of pharmacogenomic interventions
    • Phillips KA, Van Bebber SL. A systematic review of cost-effectiveness analyses of pharmacogenomic interventions. Pharmacogenomics 5, 1139-1149 (2004). Nice review of published literature of cost-effectiveness of pharmacogenomic testing.
    • (2004) Pharmacogenomics , vol.5 , pp. 1139-1149
    • Phillips, K.A.1    Van Bebber, S.L.2
  • 118
    • 20544443149 scopus 로고    scopus 로고
    • The economic implications of noninvasive molecular testing for cardiac allograft rejection
    • Evans RW, Williams GE, Baron HM et al. The economic implications of noninvasive molecular testing for cardiac allograft rejection. Am. J. Transplant. 5, 1553-1558 (2005).
    • (2005) Am. J. Transplant. , vol.5 , pp. 1553-1558
    • Evans, R.W.1    Williams, G.E.2    Baron, H.M.3


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