Completing the cycles; the dynamics of endonuclear lipidomics

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1761, Issue 5-6, 2006, Pages 577-587

  Hunt, Alan N ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Electrospray ionisation mass spectrometry; Lipidomic; Nuclear phospholipid; Phosphatidylcholine; Phosphatidylinositol; Stable isotope labelling

Indexed keywords

CHOLINE KINASE; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; CHOLINEPHOSPHOTRANSFERASE; DIACYLGLYCEROL; MULTIENZYME COMPLEX; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL; PHOSPHOLIPID;

CELL FRACTIONATION; CELL MEMBRANE; CELL NUCLEUS; CELL NUCLEUS MATRIX; CELL PROLIFERATION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME REGULATION; HUMAN; LIPID ANALYSIS; LIPID COMPOSITION; LIPID METABOLISM; LIPID TRANSPORT; LIPOGENESIS; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL CYCLE; CELL NUCLEUS; CELL PHYSIOLOGY; CELL PROLIFERATION; HUMANS; NUCLEAR ENVELOPE; PHOSPHOLIPIDS; SIGNAL TRANSDUCTION;

EUKARYOTA;

EID: 33745458102     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2006.02.013     Document Type: Review

References (94)

1. D'Santos C., Clarke J.H., Irvine R.F., and Divecha N. Nuclei contain two differentially regulated pools of diacylglycerol. Curr. Biol. 9 (1999) 437-440
2. Jackowski S. Coordination of membrane phospholipid synthesis with the cell cycle. J. Biol. Chem. 269 (1994) 3858-3867
3. Wood R., Upreti G.C., and deAntueno R.J. A comparison of lipids from liver and hepatoma subcellular membranes. Lipids 21 (1986) 292-300
4. Sanchez-Yague J., Cabezas J.A., and Llanillo M. Fatty acid composition of subcellular particles from sheep platelets and topological distribution of phosphatidylethanolamine fatty acids in the plasma membrane. Lipids 26 (1991) 878-883
5. el-Achkar P., Van Dorsselaer A., Freysz L., Mandel P., and Mersel M. Phospholipid fatty acyl group composition in mitochondria, microsomes and plasma membranes isolated from rat astrocyte primary cultures: developmental studies. Dev. Neurosci. 9 (1987) 247-254
6. Cluett E.B., Kuismanen E., and Machamer C.E. Heterogeneous distribution of the unusual phospholipid semilysobisphosphatidic acid through the Golgi complex. Mol. Biol. Cell 8 (1997) 2233-2240
7. Williams S.D., Hsu F.F., and Ford D.A. Electrospray ionization mass spectrometry analyses of nuclear membrane phospholipid loss after reperfusion of ischemic myocardium. J. Lipid Res. 41 (2000) 1585-1595
8. Hunt A.N., Clark G.T., Attard G.S., and Postle A.D. Highly saturated endonuclear phosphatidylcholine is synthesized in situ and colocated with CDP-choline pathway enzymes. J. Biol. Chem. 276 (2001) 8492-8499
9. Hunt A.N., Clark G.T., Neale J.R., and Postle A.D. A comparison of the molecular specificities of whole cell and endonuclear phosphatidylcholine synthesis. FEBS Lett. 530 (2002) 89-93
10. Hunt A.N., and Postle A.D. Phosphatidylcholine biosynthesis inside the nucleus: is it involved in regulating cell proliferation?. Adv. Enzyme Regul. 44 (2004) 173-186
11. -/- cells. Biochem. Soc. Trans. 32 (2004) 1063-1065
12. Pulfer M., and Murphy R.C. Electrospray mass spectrometry of phospholipids. Mass Spectrom. Rev. 22 (2003) 332-364
13. Han X., and Gross R.W. Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics. J. Lipid Res. 44 (2003) 1071-1079
14. Hunt A.N., and Postle A.D. Dynamic lipidomic insights into phosphatidylcholine synthesis from organelle to organism. Spectrosc.-Int. J. 19 (2005) 127-135
15. Henneberry A.L., Wright M.M., and McMaster C.R. The major sites of cellular phospholipid synthesis and molecular determinants of fatty acid and lipid head group specificity. Mol. Biol. Cell 13 (2002) 3148-3161
16. Carter J.M., Waite K.A., Campenot R.B., Vance J.E., and Vance D.E. Enhanced expression and activation of CTP:phosphocholine cytidylyltransferase beta2 during neurite outgrowth. J. Biol. Chem. 278 (2003) 44988-44994
17. Ishidate K. Choline/ethanolamine kinase from mammalian tissues. Biochim. Biophys. Acta 1348 (1997) 70-78
18. Kent C. Regulatory enzymes of phosphatidylcholine biosynthesis: a personal perspective. Biochim. Biophys. Acta 1733 (2005) 53-66
19. McMaster C.R., and Bell R.M. CDP-choline:1,2-diacylglycerol cholinephosphotransferase. Biochim. Biophys. Acta 1348 (1997) 100-110
20. Vance D.E., Choy P.C., Farren .S.B., Lim P.H., and Schneider W.J. Asymmetry of phospholipid biosynthesis. Nature 270 (1977) 268-269
21. Choy P.C., Skrzypczak M., Lee D., and Jay F.T. Acyl-GPC and alkenyl/alkyl-GPC:acyl-CoA acyltransferases. Biochim. Biophys. Acta 1348 (1997) 124-133
22. Aoyama C., Yamazaki N., Terada H., and Ishidate K. Structure and characterization of the genes for murine choline/ethanolamine kinase isozymes alpha and beta. J. Lipid Res. 41 (2000) 452-464
23. Lykidis A., and Jackowski S. Regulation of mammalian cell membrane biosynthesis. Prog. Nucleic Acid Res. Mol. Biol. 65 (2001) 361-393
24. Lykidis A., Baburina I., and Jackowski S. Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant. J. Biol. Chem. 274 (1999) 26992-27001
25. Henneberry A.L., and McMaster C.R. Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine. Biochem. J. 339 (1999) 291-298
26. Henneberry A.L., Wistow G., and McMaster C.R. Cloning, genomic organization, and characterization of a human cholinephosphotransferase. J.Biol.Chem. 275 (2000) 29808-29815
27. DeLong C.J., Qin L., and Cui Z. Nuclear localization of enzymatically active green fluorescent protein-CTP:phosphocholine cytidylyltransferase alpha fusion protein is independent of cell cycle conditions and cell types. J. Biol. Chem. 275 (2000) 32325-32330
28. Lykidis A., Jackson P., and Jackowski S. Lipid activation of CTP: phosphocholine cytidylyltransferase alpha: characterization and identification of a second activation domain. Biochemistry 40 (2001) 494-503
29. DeLong C.J., Shen Y.-J., Thomas M.J., and Cui Z. Molecular distinction of phosphatidylcholine synthesis between the CDPcholine pathway and phosphatidylethanolamine methylation pathway. J. Biol. Chem. 274 (1999) 29683-29688
30. Postle A.D. Composition and role of phospholipids in the body. In: Sadler M., Caballero B., and Strain S. (Eds). Encyclopedia of Human Nutrition (1998), Academic Press, London 1193-1201
31. Hunt A.N., Burdge G.C., and Postle A.D. Phospholipid composition of neonatal guinea pig liver and plasma: effect of postnatal food restriction. Lipids 31 (1996) 489-495
32. Hunt A.N., Kelly F.J., and Postle A.D. Developmental variation in whole human lung phosphatidylcholine molecular species: a comparison with guinea pig and rat. Early Hum. Dev. 25 (1991) 157-171
33. Schneiter R., Brugger B., Sandhoff R., Zellnig G., Leber A., Lampl M., Athenstaedt K., Hrastnik C., Eder S., Daum G., Paltauf F., Wieland F.T., and Kohlwein S.D. Electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of the lipid molecular species composition of yeast subcellular membranes reveals acyl chain-based sorting/remodeling of distinct molecular species en route to the plasma membrane. J. Cell Biol. 146 (1999) 741-754
34. Surette M.E., and Chilton F.H. The distribution and metabolism of arachidonate-containing phospholipids in cellular nuclei. Biochem. J. 330 (1998) 915-921
35. Balsinde J. Roles of various phospholipases A2 in providing lysophospholipid acceptors for fatty acid phospholipid incorporation and remodelling. Biochem. J. 364 (2002) 695-702
36. Hunt A.N. Dynamic lipidomics of the nucleus. J. Cell. Biochem. 97 (2006) 244-251
37. Rose H.G., and Frenster J.H. Composition and metabolism of lipids within repressed and active chromatin of interphase lymphocytes. Biochim. Biophys. Acta 106 (1965) 577-591
38. Albi E., Mersel M., LeRay C., Tomassoni M.L., and ViolaMagni M.P. Rat liver chromatin phospholipids. Lipids 29 (1994) 715-719
39. Maraldi N.M., Santi S., Zini N., Ognibene A., Rizzoli R., Mazzotti G., Di Primo R., Baregg R., Bertagnolo V., Pagliarini C., and Capitani S. Decrease in nuclear phospholipids associated with DNA replication. J. Cell Sci. 104 (1993) 853-859
40. Martelli A.M., Bortul R., Tabellini G., Bareggi L.R., Manzoli L., Narducci P., and Cocco L. Diacylglycerol kinases in nuclear lipid-dependent signal transduction pathways. Cell. Mol. Life Sci. 59 (2002) 1129-1137
41. Vann L.R., Wooding F.B.P., Irvine R.F., and Divecha N. Metabolism and possible compartmentalization of inositol lipids in isolated rat-liver nuclei. Biochem. J. 327 (1997) 569-576
42. Osborne S.L., Thomas C.L., Gschmeissner S., and Schiavo G. Nuclear PtdIns(4,5)P2 assembles in a mitotically regulated particle involved in pre-mRNA splicing. J. Cell Sci. 114 (2001) 2501-2511
43. Maraldi N.M., Zini N., Santi S., and Manzoli F.A. Topology of inositol lipid signal transduction in the nucleus. J. Cell. Physiol. 181 (1999) 203-217
44. Attard G.S., Templer R.H., Smith W.S., Hunt A.N., and Jackowski S. Modulation of CTP:phosphocholine cytidylyltransferase by membrane curvature elastic stress. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 9032-9036
45. Hunt A.N., Normand I.C.S., and Postle A.D. CTP:cholinephosphate cytidylyltransferase in human and rat lung: association in vitro with cytoskeletal actin. Biochim. Biophys. Acta 1043 (1990) 19-26
46. Bladergroen B.A., Geelen M.J., Reddy A.C., Declercq P.E., and Van Golde L.M.G. Channelling of intermediates in the biosynthesis of phosphatidylcholine and phosphatidylethanolamine in mammalian cells. Biochem. J. 334 (1998) 511-517
47. Echevarria W., Leite M.F., Guerra M.T., Zipfel W.R., and Nathanson M.H. Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum. Nat. Cell Biol. 5 (2003) 440-446
48. Ralle T., Grund C., Franke W.W., and Stick R. Intranuclear membrane structure formations by CaaX-containing nuclear proteins. J. Cell Sci. 117 (2004) 6095-6104
49. Marius P., Guerra M.T., Nathanson M.H., Ehrlich B.E., and Leite M.F. Calcium release from ryanodine receptors in the nucleoplasmic reticulum. Cell Calcium 39 (2006) 65-73
50. Lagace T.A., and Ridgway N.D. The rate-limiting enzyme in phosphatidylcholine synthesis regulates proliferation of the nucleoplasmic reticulum. Mol. Biol. Cell 16 (2005) 1120-1130
51. Fricker M., Hollinshead M., White N., and Vaux D. Interphase nuclei of many mammalian cell types contain deep, dynamic, tubular membrane-bound invaginations of the nuclear envelope. J. Cell Biol. 136 (1997) 531-544
52. Sorensen V., Brech A., Khnykin D., Kolpakova E., Citores L., and Olsnes S. Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus. J. Cell Sci. 117 (2004) 1807-1819
53. Lewis J.D., and Tollervey D. Like attracts like: getting RNA processing together in the nucleus. Science 288 (2000) 1385-1389
54. Boshier D.P., Holloway H., and Kitchin L.F. A comparison of standard lipid staining techniques used in electron microscopic studies of mammalian tissues. Stain Technol. 59 (1984) 83-89
55. Hunt A.N., and Burdge G.C. Chromatin-associated phosphatidylcholine synthesis. Biochem. Soc. Trans. 26 (1998) S223
56. Martelli A.M., Fala F., Faenza I., Billi A.M., Cappellini A., Manzoli L., and Cocco L. Metabolism and signaling activities of nuclear lipids. Cell. Mol. Life Sci.. 61 (2004) 1143-1156
57. Struchkov V.A., and Strazhevskaya N.B. Structural and functional aspects of nuclear lipids in normal and tumor cells. Biochemistry (Mosc.) 65 (2000) 525-545
58. Albi E., and Viola-Magni M.P. The role of intranuclear lipids. Biol. Cell 96 (2004) 657-667
59. Henry S.M., and Hodge L.D. Evidence for a unique profile of phosphatidylcholine synthesis in late mitotic cells. J. Cell Biol. 97 (1983) 166-172
60. Dixon J.F., and Hokin L.E. Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase. J. Biol. Chem. 259 (1984) 14418-14425
61. Hirai H., Natori S., and Sekimizu K. Reversal by phosphatidylglycerol and cardiolipin of inhibition of transcription and replication by histones in vitro. Arch. Biochem. Biophys. 298 (1992) 458-463
62. Anthony P., Kanfer J.N., and Freysz L. Phosphatidylcholine metabolism in nuclei of phorbol ester-activated LA-N-1 neuroblastoma cells. Neurochem. Res. 25 (2000) 1073-1082
63. Hunt A.N., Burdge G.C., Wright S.M., and Postle A.D. S phase depletion of nuclear CTP:choline phosphate cytidylyltransferase. Biochem. Soc. Trans. 26 (1998) S222
64. Cornell R.B., and Northwood I.C. Regulation of CTP:phosphocholine cytidylyltransferase by amphitropism and relocalization. Trends Biochem. Sci. 25 (2000) 441-447
65. Rubbini S., Cocco L., Manzoli L., Lutterman J., Billi A.M., Matteucci A., and Wirtz K.W.A. Phosphoinositide signalling in nuclei of Friend cells: DMSO-induced differentiation reduces the association of phosphatidylinositol-transfer protein with the nucleus. Biochem. Biophys. Res. Commun. 230 (1997) 302-305
66. Routt S.M., and Bankaitis V.A. Biological functions of phosphatidylinositol transfer proteins. Biochem. Cell. Biol. 82 (2004) 254-262
67. Alb J.G., Cortese J.D., Phillips S.E., Albin R.L., Nagy T.R., Hamilton B.A., and Bankaitis V.A. Mice lacking phosphatidylinositol transfer protein-alpha exhibit spinocerebellar degeneration, intestinal and hepatic steatosis, and hypoglycaemia. J. Biol. Chem. 278 (2003) 33501-33518
68. Hunt A.N., Skippen A.J., Koster G., Postle A.D., and Cockcroft S. Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha. Biochim. Biophys. Acta 1686 (2004) 50-60
69. Bankaitis V.A., Cortese J., Phillips S.E., and Alb Jr. J.G. Phosphatidylinositol transfer protein function in the mouse. Adv. Enzyme Regul. 44 (2004) 201-218
70. Freyberg Z., Sweeney D., Siddhanta A., Bourgoin S., Frohman M., and Shields D. Intracellular localization of phospholipase D1 in mammalian cells. Mol. Biol. Cell 12 (2001) 943-955
71. Freyberg Z., Bourgoin S., and Shields D. Phospholipase D2 is localized to the rims of the Golgi apparatus in mammalian cells. Mol. Biol. Cell 13 (2002) 3930-3942
72. Antony P., Freysz L., Horrocks L.A., and Farooqui A.A. Effect of retinoic acid on the Ca2+-independent phospholipase A2 in nuclei of LA-N-1 neuroblastoma cells. Neurochem. Res. 26 (2001) 83-88
73. Martelli A.M., Fiume R., Faenza I., Tabellini G., Evangelisti C., Bortul R., Follo M.Y., Falà F., and Cocco L. Nuclear phosphoinositide specific phospholipase C (PI-PLC)-beta 1: a central intermediary in nuclear lipid-dependent signal transduction. Histol. Histopathol. 20 (2005) 1251-1260
74. Albi E., and Viola-Magni M.P. Chromatin-associated sphingomyelin: metabolism in relation to cell function. Cell Biochem. Funct. 21 (2003) 211-215
75. Martelli A.M., Mazzotti G., and Capitani S. Nuclear protein kinase C isoforms and apoptosis. Eur. J. Histochem. 48 (2004) 89-94
76. Li Y., Choi M., Cavey G., Daugherty J., Suino K., Kovach A., Bingham N.C., Kliewer S.A., and Xu H.E. Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1. Mol. Cell 17 (2005) 491-502
77. Forman B.M. Are those phospholipids in your pocket?. Cell Metab. 1 (2005) 153-155
78. Irvine R.F. Nuclear lipid signalling. Nat. Rev., Mol. Cell Biol. 4 (2003) 349-360
79. Topham M.K., Bunting M., Zimmerman G.A., McIntyre T.M., Blackshear P.J., and Prescott S.M. Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta. Nature 394 (1998) 697-700
80. Lagace T.A., Miller J.A., and Ridgway N.D. Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis. Mol. Biol. Cell 22 (2002) 4851-4862
81. Hodgkin M.N., Pettitt T.R., Martin A., Michell R.H., Pemberton A.J., and Wakelam M.J. Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?. Trends Biochem. Sci. 23 (1998) 200-204
82. Postle A.D., Heeley E.L., and Wilton D.C. A comparison of the molecular species compositions of mammalian lung surfactant phospholipids. Comp. Biochem. Physiol., A 129 (2001) 65-73
83. Mander A., Langton-Hewer S., Bernhard W., Warner J.O., and Postle A.D. Altered phospholipid composition and aggregate structure of lung surfactant is associated with impaired lung function in young children with respiratory infections. Am. J. Respir. Cell Mol. Biol. 27 (2002) 714-721
84. Postle A.D. The role of pulmonary surfactant in the asthmatic response. Clin. Exp. Allergy 30 (2000) 1201-1204
85. Veldhuizen E.J., and Haagsman H.P. Role of pulmonary surfactant components in surface film formation and dynamics. Biochim. Biophys. Acta 1467 (2000) 255-270
86. Kharakoz D.P., Khusainova R.S., Gorelov A.V., and Dawson K.A. Stoichiometry of dipalmitoylphosphatidylcholine-DNA interaction in the presence of Ca2+: a temperature-scanning ultrasonic study. FEBS Lett. 446 (1999) 27-29
87. Struchkov V.A., Strazhevskaya N.B., and Zhdanov R.I. DNA-bound lipids of normal and tumor cells: retrospective and outlooks for functional genomics. Bioelectrochemistry 58 (2002) 23-30
88. Quesada I., Rovira J.M., Martin F., Roche E., Nadal A., and Soria B. Nuclear KATP channels trigger nuclear Ca(2+) transients that modulate nuclear function. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 9544-9549
89. Tabellini G., Bortul R., Santi S., Riccio M., Baldini G., Cappellini A., Billi A.M., Berezney R., Ruggeri A., Cocco L., and Martelli A.M. Diacylglycerol kinase-θ is localized in the speckle domains of the nucleus. Exp. Cell Res. 287 (2003) 143-154
90. Huh Y.H., Chu S.Y., Park S.Y., Huh S.K., and Yoo S.H. Role of nuclear chromogranin B in inositol 1,4,5-trisphosphate-mediated nuclear Ca(2+) mobilization. Biochemistry 45 (2006) 1212-1226
91. Milne S.B., Ivanova P.T., DeCamp D., Hsueh R.C., and Brown H.A. A targeted mass spectrometric analysis of phosphatidylinositol phosphate species. J. Lipid Res. 46 (2005) 1796-1802
92. Sierra-Honigmann M.R., Bradley J.R., and Pober J.S. Cytosolic phospholipase A2 is in the nucleus of subconfluent endothelial cells but confined to the cytoplasm of confluent endothelial cells and redistributes to the nuclear envelope and cell junctions upon histamine stimulation. Lab. Invest. 74 (1996) 684-695
93. Fayard J.M., Tessier C., Pageaux J.F., Lagarde M., and Laugier C. Nuclear location of PLA2-I in proliferative cells. J. Cell Sci. 111 (1998) 985-994
94. Oishi T., Tamiya-Koizumi K., Kudo I., Iino S., Takagi K., and Yoshida S. Purification and characterization of nuclear alkaline phospholipase A2 in rat ascites hepatoma cells. FEBS Lett. 394 (1996) 55-60