Dynamic lipidomic insights into phosphatidylcholine synthesis from organelle to organism

Spectroscopy

Volumn 19, Issue 3, 2005, Pages 127-135

  Hunt, Alan N ^a,b   Postle, Anthony D ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Electrospray ionisation mass spectrometry; Lipidomics; Molecular species; Phosphatidylcholine; Phospholipid; Stable isotope

Indexed keywords

DERIVATIVES; IONIZATION; ISOTOPES; MASS SPECTROMETRY; METABOLISM; PHOSPHOLIPIDS;

ELECTROSPRAY IONIZATION MASS SPECTROMETRY; LIPIDOMICS; MOLECULAR SPECIES; PHOSPHATIDYLCHOLINE; STABLE ISOTOPES;

BIOCHEMISTRY;

CHOLINE DERIVATIVE; DEUTERIUM; PHOSPHATIDYLCHOLINE;

CELL COMPARTMENTALIZATION; CELL ORGANELLE; CHOLINE UPTAKE; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIPID COMPOSITION; LIPID METABOLISM; MASS SPECTROMETRY; MEDICAL RESEARCH; METABOLOMICS; MOLECULAR BIOLOGY; NONHUMAN; PHOSPHOLIPID SYNTHESIS; SENSITIVITY AND SPECIFICITY; SHORT SURVEY; TANDEM MASS SPECTROMETRY;

EID: 23944479733     PISSN: 07124813     EISSN: None     Source Type: Journal    
DOI: 10.1155/2005/262140     Document Type: Short Survey

References (35)

1. J.J. Batenburg and H.P. Haagsman, The lipids of pulmonary surfactant: dynamics and interactions with proteins, Prog. Lipid Res. 37 (1998), 235-276.
2. W. Bernhard, M. Linck, H. Creutzburg, A.D. Postle, A. Arning, I. Martin-Carrera and K.F. Sewing, High-performance liquid chromatographic analysis of phospholipids from different sources with combined fluorescence and ultraviolet detection, Anal. Biochem. 220 (1994), 172-180.
3. W. Bernhard, C.J. Pynn, A. Jaworski, G.A. Rau, J.M. Hohlfeld, J. Freihorst, C.F. Poets, D. Stoll and A.D. Postle, Mass spectrometric analysis of surfactant metabolism in human volunteers using deuteriated choline, Am. J. Respir. Crit. Care Med. 170 (2004), 54-58.
4. H.A. Boumann, P.T. Chin, A.J. Heck, B. de Kruijff and A.I. de Kroon, The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert diC16:1 substrates both in vivo and in vitro, J. Biol. Chem. 279 (2004), 40314-41319.
5. H.A. Boumann, M.J. Damen, C. Versluis, A.J. Heck, B. de Kruijff and A.I. de Kroon, The two biosynthetic routes leading to phosphatidylcholine in yeast produce different sets of molecular species. Evidence for lipid remodeling, Biochemistry 42 (2003), 3054-3059.
6. H.A. Boumann, B. de Kruijff, A.J. Heck and A.I. de Kroon, The selective utilization of substrates in vivo by the phosphatidylethanolamine and phosphatidylcholine biosynthetic enzymes Epot1p and Cpt1p in yeast, FEBS Lett. 569 (2004), 173-177.
7. G.C. Burdge, A.N. Hunt and A.D. Postle, Mechanisms of hepatic phosphatidylcholine synthesis in adult rat: effects of pregnancy, Biochem. J. 303 (1994), 941-947.
8. G.C. Burdge, F.J. Kelly and A.D. Postle, Synthesis of phosphatidylcholine in guinea-pig fetal lung involves acyl remodelling and differential turnover of individual molecular species, Biochim. Biophys. Acta 1166 (1993), 251-257.
9. P.A. Caesar, S.J. Wilson, I.C.S. Normand and A.D. Postle, A comparison of the specificity of phosphatidylcholine synthesis by human fetal lung maintained in either organ or organotypic culture, Biochem. J. 253 (1988), 451-457.
10. J.M. Carter, K.A. Waite, R.B. Campenot, J.E. Vance and D.E. Vance, Enhanced expression and activation of CTP:phosphocholine cytidylyltransferase beta2 during neurite outgrowth, J. Biol. Chem. 278 (2003), 44988-44994.
11. P.E. Cogo, L.J. Zimmermann, L. Meneghini, N. Mainini, L. Bordignon, V. Suma, M.Buffo and V.P. Carnielli, Pulmonary surfactant disaturated- phosphatidylcholine (DSPC) turnover and pool size in newborn infants with congenital diaphragmatic hernia (CDH), Pediatr. Res. 54 (2003), 653-658.
12. P.E. Cogo, L.J. Zimmermann, G. Verlato, P. Midrio, A. Gucciardi, C. Ori and V.P. Carnielli, A dual stable isotope tracer method for the measurement of surfactant disaturated-phosphatidylcholine net synthesis in infants with congenital diaphragmatic hernia, Pediatr. Res. 56 (2004), 184-190.
13. C.J. DeLong, A.M. Hicks and Z. Cui, Disruption of choline methyl group donation for phosphatidylethanolamine methylation in hepatocarcinoma cells, J. Biol. Chem. 277 (2002), 17217-17225.
14. C.J. DeLong, Y.J. Shen, M.J. Thomas and Z. Cui, Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and the phosphatidylethanolamine methylation pathway, J. Biol. Chem. 274 (1999), 29683-29688.
15. C. Enjalbal, R. Roggero, R. Cerdan, J. Martinez. H. Vial and J.L. Aubagnac, Automated monitoring of phosphatidylcholine biosyntheses in plasmodium falciparum by electrospray ionization mass spectrometry through stable isotope labeling experiments, Anal. Chem. 76 (2004), 4515-4521.
16. M. Gobley, Examen comparatif du jaune d'oeufe et de al matiere cerebrale, J. Pharm. Chim. 11 (1847), 409.
17. X. Han and R.W. Gross, Global analyses of cellular lipidomes directly from crade extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics, J. Lipid Res. 44 (2003), 1071-1079.
18. A.L. Henneberry, M.M. Wright and C.R. McMaster, The major sites of cellular phospholipid synthesis and molecular determinants of fatty acid and lipid head group specificity, Mol. Biol. Cell. 13 (2002), 3148-3161.
19. -/- cells, Biochem. Soc. Trans. 32 (2004), 1063-1065.
20. A.N. Hunt, G.T. Clark, G.S. Attard and A.D. Postle, Highly saturated endonuclear phosphatidylcholine is synthesized in situ and colocated with CDP-choline pathway enzymes, J. Biol. Chem. 276 (2001), 8492-8499.
21. A.N. Hunt, G.T. Clark, J.R. Neale and A.D. Postle, A comparison of the molecular specificities of whole cell and endonuclear phosphatidylcholine synthesis, FEBS Lett. 530 (2002), 89-93.
22. A.N. Hunt, H.C. Fenn, G.T. Clark, M.M. Wright, A.D. Postle and C.R. McMaster, Lipidomic analysis of the molecular specificity of a cholinephosphotransferase in situ, Biochem. Soc. Trans. 32 (2004), 1060-1062.
23. A.N. Hunt, F.J. Kelly and A.D. Postle, Developmental variation in whole human lung phosphatidylcholine molecular species: a comparison with guinea pig and rat, Early Hum. Dev. 25 (1991), 157-171.
24. A.N. Hunt and A.D. Postle, Phosphatidylcholine biosynthesis inside the nucleus: is it involved in regulating cell proliferation?, Adv. Enz. Regul. 44(2004), 173-186.
25. A.N. Hunt, A.J. Skippen, G. Koster, A.D. Postle and S. Cockcroft, Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha, Biochim. Biophys. Acta 1686 (2004), 50-60.
26. S.G. Ostrowski, C.T. Van Bell, N. Winograd and A.G. Ewing, Mass spectrometric imaging of highly curved membranes during Tetrahymena mating, Science 305 (2004), 71-73.
27. A.D. Postle, H. Dombrowsky, H. Clarke, C.J. Pynn, G. Koster and A.N. Hunt, Mass spectroscopic analysis of phosphatidylinositol synthesis using 6-deuteriated-myo-inositol: comparison of the molecular specificities and acyl remodelling mechanisms in mouse tissues and cultured cells, Biochem. Soc. Trans. 32 (2004), 1057-1059.
28. A.D. Postle, J. Madden, G.T. Clark and S.M. Wright, Electrospray ionization mass spectrometry analysis of differential turnover of phosphatidylcholine by human blood leukocytes, Phys. Chem. Chem. Phys. 6 (2004), 1018-1021.
29. A.D. Postle, Method for the sensitive analysis of individual molecular species of phosphatidylcholine by high-performance liquid chromatography using post-column fluorescence detection, J. Chromatogr. 415 (1987), 241-251.
30. M. Pulfer and R.C. Murphy, Electrospray mass spectrometry of phospholipids, Mass Spectrom. Rev. 22 (2003), 332-364.
31. S. Ruggierri, R. Roblin and P.H. Black, Lipids of whole cells and plasma membrane fractions from Balb/c3T3, SV3T3, and concanavalin A-selected revertant cells, J. Lipid Res. 20 (1979), 760-771.
32. K. Tran, Y. Wang, C.J. DeLong and Z. Cui, The assembly of very low density lipoproteins in rat hepatoma McA-RH7777 cells is inhibited by phospholipase A2 antagonists, J. Biol. Chem. 275 (2000), 25023-25030.
33. J.T. Venkatraman, T. Toohey and M.T. Clandinin, Does a threshold for the effect of dietary omega-3 fatty acids on the fatty acid composition of nuclear envelope phospholipids exist?, Lipids 27 (1992), 94-97.
34. G. Verlato, P.E. Cogo, E. Benetti, S. Gomirato, A. Gucciardi and V.P. Carnielli, Kinetics of surfactant in respiratory diseases of the newborn infant, J. Matern. Fetal Neonatal Med. 16(Suppl. 2) (2004), 21-24.
35. S.D. Williams, F.F. Hsu, D.A. Ford, Electrospray ionization mass spectrometry analyses of nuclear membrane phospholipid loss after reperfusion of ischemic myocardium, J. Lipid Res. 41 (2000), 1585-1595.