Disseminated Mycobacterium avium complex infection in AIDS: Immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D

Journal of Infectious Diseases

Volumn 173, Issue 1, 1996, Pages 259-262

  Haug, Charlotte J ^a   Aukrust, Pål ^b   Lien, Egil ^b   Müller, Fredrik ^b   Espevik, Terje ^b   Frøland, Stig S ^b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; BLOOD LEVEL; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MYCOBACTERIOSIS; MYCOBACTERIUM INTRACELLULARE AVIUM; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROSPECTIVE STUDY; VITAMIN DEFICIENCY;

EID: 0030066016     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/173.1.259     Document Type: Article

References (15)

1. Wallis RS, Ellner JJ, Shiratsuchi H. Macrophages, mycobacteria and HIV: the role of cytokines in determining mycobacterial virulence and regulating viral replication. Res Microbiol 1992;143:398-405.
2. Tartagila LA, Goeddel DV. Two TNF receptors. Immunol Today 1992;13:151-3.
3. Aukrust P, Liabakk NB, Müller F, Lien E, Espevik T, Frøland SS. Serum levels of tumor necrosis factor-α (TNFα) and soluble TNF receptors in human immunodeficiency virus type 1 infection - correlations to clinical, immunologic, and virologie parameters. J Infect Dis 1994;169:420-4.
4. Haug C, Müller F, Aukrust P, Frøland SS. Subnormal serum concentration of 1,25-vitamin D in human immunodeficiency virus infection: correlation with degree of immune deficiency and survival. J Infect Dis 1994;169:889-93.
5. Davies PDO. A possible link between vitamin D deficiency and impaired host defence to Mycobacterium tuberculosis. Tubercle 1985;66:301-6.
6. Rook GA, Taverne J, Leveton C, Steele J. The role of gamma-interferon, vitamin D3 metabolites and tumour necrosis factor in the pathogenesis of tuberculosis. Immunology 1987;62:229-34.
7. Smeland EB, Blomhoff HK, Funderud S, Shalaby MR, Espevik T. Interleukin 4 induces selective production of interleukin 6 from normal human B lymphocytes. J Exp Med 1989;170:1463-8.
8. Filley EA, Bull HA, Dowd PM, Rook GA. The effect of Mycobacterium tuberculosis on the susceptibility of human cells to the stimulatory and toxic effects of tumour necrosis factor. Immunology 1992;77:505-9.
9. Bogdan C, Nathan C. Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10. Ann NY Acad Sci 1993;685:713-39.
10. Müller F, Rollag H, Frøland SS. Reduced oxidative burst responses in monocytes and monocyte-derived macrophages from HIV-infected subjects. Clin Exp Immunol 1990;82:10-5.
11. Cope AP, Londei M, Chu NR, et al. Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex: reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis. J Clin Invest 1994;94:749-60.
12. Zhang Y, Nakata K, Weiden M, Rom WN. Mycobacterium tuberculosis enhances human immunodeficiency virus-1 replication by transcriptional activation at the long terminal repeat. J Clin Invest 1995;95:2324-31.
13. Breslau NA. Normal and abnormal regulation of 1,25-(OH)2D synthesis. Am J Med Sci 1988;296:417-25.
14. Abu-Amer Y, Bar-Shavit Z. Regulation of TNF-alpha release from bone marrow-derived macrophages by vitamin D. J Cell Biochem 1994;55:435-44.
15. Kuno H, Kurian SM, Hendy GN, et al. Inhibition of 1,25-dihydroxyvitamin D3 stimulated osteocalcin gene transcription by tumor necrosis factor-alpha: structural determinants within the vitamin D response element. Endocrinology 1994:134:2524-31.