High risk of HIV-related mortality is associated with selenium deficiency

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology

Volumn 15, Issue 5, 1997, Pages 370-374

  Baum, Marianna K ^a   Shor Posner, Gail ^a   Lai, Shenghan ^a   Zhang, Guoyan ^a   Lai, Hong ^a   Fletcher, Mary Ann ^a   Sauberlich, Howerde ^b   Page, J Bryan ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

HIV infection; Mortality; Nutrition; Selenium

Indexed keywords

ALPHA TOCOPHEROL; CD4 ANTIGEN; CYANOCOBALAMIN; RETINOL; SELENIUM; ZIDOVUDINE; ZINC;

ADULT; ARTICLE; FEMALE; HIGH RISK POPULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONGITUDINAL STUDY; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; MORTALITY; PRIORITY JOURNAL; SELENIUM DEFICIENCY; VITAMIN DEFICIENCY; ZINC DEFICIENCY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030669818     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199708150-00007     Document Type: Article

References (42)

1. Polk BF, Fox R, Brookmeyer R, et al. Predictors of the acquired immunodeficiency syndrome developing in a cohort of seropositive homosexual men. N Engl J Med 1987;316:61-6.
2. Mann D, Murray C, Yarchoan R. Nlattner WA, Goedert JJ. HLA antigen frequencies in HIV-1 seropositive disease-free individuals and patients with AIDS. J Acquir Immune Defic Syndr 1988;1: 13-7.
3. Cheng-Meyer C, Seta D, Tateno M, Levy JA. Biological features of HIV-1 that correlate virulence in the host. Science 1988;240: 80-2.
4. Blaxhult A, Granath F, Lidman K, Giesecke J. The influence of age on the latency period to AIDS in people infected by HIV through blood transfusion. AIDS 1990;4:125-9.
5. Des Jarlais DC, Friedman SR, Marmor M, et al. Development of AIDS. HIV seroconversion, and potential cofactors for T4 cell loss in a cohort of intravenous drug users. AIDS 1987;1:105-11.
6. Baum MK, Shor-Posner G, Lu Y, et al. Micronutrients and HIV-1 disease progression. AIDS 1995;9:1051-6.
7. Semba RD, Graham N, Caiaffa WT, Margolick JB, Vlement L, Vlahov D. Increased mortality associated with vitamin A deficiency during human immunodeficiency virus type 1 infection. Arch Intern Med 1993;153:2149-54.
8. Serwadda D, Murgewa D, Sewankamboo NK, et al. Slim disease: new disease in Uganda and its association with HTLV-III infection. Lancet 1985;2:849-52.
9. Malebranchi R, Arnoux E, Guerin JM, et al. Acquired immunodeficiency syndrome with severe gastrointestinal manifestations in Haiti. Lancet 1983;2:873-7.
10. Beach RS, Mantero-Atienza E, Shor-Posner G, et al. Specific nutrient abnormalities in asymptomatic HIV-1 infection. AIDS 1992; 6:701.
11. 6 status with parameters of immune function in early HIV-1 infection. J Acquir Immune Defic Syndr 1991;4:1122-32.
12. Shetty PS, Jung RT, Stampler M, et al. Rapid turnover transport proteins: an index of subclinical protein-energy malnutrition. Lancet 1979;2:230-2.
13. Fletcher MA, Gjerset GJ, Hassett J, et al. and the Transfusion Safety Study. Effect of age on HIV-1 induced changes in lymphocytes populations among persons with congenital clotting disorders. Blood 1992;80:831-40.
14. Graham NMH, Sorensen D, Odaka N, et al. Relationship of serum copper and zinc levels to HIV-1 seropositivity and progression to AIDS. J Acquir Immune Defic Syndr 1991;4:976-80.
15. Bologna R, Indacochea F, Shor-Posner G, et al. Selenium and immunity in HIV-1-infected pediatric patients. J Nutr Immunol 1994;3:41-9.
16. Campa A, Shor-Posner G. Scott GB, et al. Mortality risk in selenium deficient HIV+ children. AIDS (in press).
17. Constans J, Pellegrin JL, Sergeant C, et al. Serum selenium predicts outcome in HIV infection [letter]. J Acquir Immune Defic Syndr 1995;10:392.
18. Cohen HJ, Brown M, Hamilton D, Lyons-Patterson J, Avissar N, Liegey P. Glutathione peroxidase and selenium deficiency in patients receiving home parenteral nutrition: time course for development of deficiency and repletion of enzyme activity in plasma and blood cell. Am J Clin Nutr 1989;49:132-9.
19. Lockitch G. Selenium: clinical significance and analytical concepts. Crit Rev Clin Lab Sci 1989;27:483-541.
20. Dworkin BM, Rosenthal WS, Wormser GP, et al. Abnormalities of blood selenium and glutathione peroxidase in patients with acquired immunodeficiency syndrome and AIDS-related complex. Biol Trace Elem Res 1988;20:86-96.
21. Cirelli A, Ciardi M, De Simone C, et al. Serum selenium concentration and disease progress in patients with HIV infection. Clin Biochem 1991;24:211-4.
22. Mantero-Atienza E, Sotomayor MG, Shor-Posner G, et al. Selenium status and immune function in asymptomatic HIV-1 seropositive men. Nutr Res 1991;11:1237-50.
23. Staat FJT, Ela SW, Roederer M, Anderson MT, Herzenberg LA. Glutathione deficiency and human immunodeficiency virus infection. Lancet 1992;339:909-12.
24. Allavena C, Dousset B, May T, Dubors F, Canton P, Nelleville F. Relationship of trace element, immunological markers, and HIV-1 infection progression. Biol Trace Elem Res 1995;47:133-8.
25. Papadopulos-Eleopulos E. Reappraisal of AIDS - is the oxidation induced by the risk factors the primary cause? Med Hypotheses 1988;25:151-62.
26. Revillard JP, Vincent CMA, Favier AE, et al. Lipid peroxidation in human immunodeficiency virus infection. J Acquir Immune Defic Syndr 1992;5:637-8.
27. Sappey C, Favier A, Leclercq P, Micoud M, Faure P, Pelen F. Relative decrease in antioxidant status during evolution of HIV infection: effect on lipid peroxidation [Abstract 7502]. Presented at the VIIIth International Conference on AIDS. Amsterdam, The Netherlands, July 19-24, 1992.
28. Repetto M, Reides C, Gomez Carrelero ML, Costa M, Griemberg G, Llesuy S. Oxidative stress in blood of HIV-infected patients. Clin Chim Acta 1996;255:107-17.
29. Pace GW, Leaf CD. The role of oxidative stress in HIV disease. Free Radic Biol Med 1995;19(4):523-528.
30. Sonnerberg A, Cailin G, Akerlund B, Jarstrand C. Increased production of malondialdehyde in patients with HIV infection. Soc J Infect Dis 1988;20:287-90.
31. Malvy DJ-M, Richard M-J, Arnaud J, Favier A, Amedee-Manesme O. Relationship of plasma malondialdehyde, vitamin E and antioxidant micronutrients to human immunodeficiency virus-1 seropositivity. Clin Chim Acta 1994;224:89-94.
32. Halliwell B. Oxidants and human disease: some new concepts. FASEB J 1987;1:358-64.
33. Shu-Yu Y, Lu XP, Liao SD. Selenium stimulates c-fos and suppresses c-myc gene expression in human hepatoma cells. In: Collery P, Priorier LA, Manfait M, Etienne JC, eds. Metal ions in biology and medicine. Paris: John Libbey Eurotext, 1990:487.
34. Sappey C, Legrand-Poels S, Best-Belpomme M, Favier A, Rentier B, Peitte J. Stimulation of glutathione peroxidase activity decreases HIV type 1 activation after oxidative stress. AIDS Res Hum Retroviruses 1994;10:1451-61.
35. Taylor EW, Ramanathan CS, Jallurl RK, Nadimpalli RG. A basis for new approaches to the chemotherapy of AIDS: novel genes in HIV-1 potentially encode selenoproteins expressed by ribosomal frameshifting and termination suppression. J Med Chem 1994;37: 2637-54.
36. Senkevitch G, Bugert JJ, Sisler JR, Koonin EV, Darai G, Moss B. Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes. Science 1996;273:813-6.
37. Bock A, Forchammer K, Heider J, et al. Selenocysteine: the 21st amino acid. Mol Microbiol 1991;5:15-20.
38. Ramanathan CS, Taylor EW. Computational genomic analysis of hemorrhagic fever viruses: viral selenoproteins as a potential factor in pathogenesis. Biol Trace Elem Res 1997;56:93-106.
39. Battigello JMA, Cui M, Roshong S, Carter B. Enediyne mediated cleavage of RNA. Biol Org Med Chem 1995;3:839-49.
40. Taylor EW, Nadimpalli RG, Ramanathan CS. Genomic structures of viral agents in relation to the biosynthesis of selenoproteins. Biol Trace Elem Res 1997;56:63-91.
41. Taylor EW, Ramanathan CS, Nadimpalli RG, Schinazi RF. Do some viruses encode selenoproteins? Assessment of the theory in the light of current theoretical, experimental and clinical data. Antiviral Res 1995;26:A271-86.
42. Delmas-Beauvieux M-C, Peuchant E, Coucouron A, et al. The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or β-carotene. Am J Clin Nutr 1996;64:101-7.