A Proximal Arginine R206 Participates in Switching of the Bradyrhizobium japonicum FixL Oxygen Sensor

Journal of Molecular Biology

Volumn 360, Issue 1, 2006, Pages 80-89

  Gilles Gonzalez, Marie Alda ^a   Caceres, Ana Isabel ^b   Sousa, Eduardo Henrique Silva ^a   Tomchick, Diana R ^a   Brautigam, Chad ^a   Gonzalez, Constancio ^b   Machius, Mischa ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

FixJ; PAS domain; response regulator; sensor kinase; two component system

Indexed keywords

ARGININE; CYANIDE; FERRIC ION; HEME; HEME PROPIONATE 7; LIGAND; OXYGEN; PORPHYRIN; PROPIONIC ACID DERIVATIVE; PROTEIN HISTIDINE KINASE; PROTEIN HISTIDINE KINASE FIXL; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOSENSOR; BRADYRHIZOBIUM JAPONICUM; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; ESCHERICHIA COLI; FUNCTIONAL ASSESSMENT; GENE SWITCHING; GENETIC VARIABILITY; LIGAND BINDING; NONHUMAN; OXYGEN AFFINITY; OXYGEN SATURATION; OXYGEN SENSING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SUBSTITUTION REACTION; WILD TYPE;

BRADYRHIZOBIUM JAPONICUM;

EID: 33745240395     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.04.054     Document Type: Article

References (32)

1. Gilles-Gonzalez M.A., and Gonzalez G. Heme-based sensors: defining characteristics, recent developments, and regulatory hypotheses. J. Inorg. Biochem. 99 (2005) 1-22
2. Gilles-Gonzalez M.A., and Gonzalez G. Signal transduction by heme-containing PAS-domain proteins. J. Appl. Physiol. 96 (2004) 774-783
3. Gong W., Hao B., Mansy S.S., Gonzalez G., Gilles-Gonzalez M.A., and Chan M.K. Structure of a biological oxygen sensor: a new mechanism for heme-driven signal transduction. Proc. Natl Acad. Sci. USA 95 (1998) 15177-15182
4. Delgado-Nixon V.M., Gonzalez G., and Gilles-Gonzalez M.A. Dos, a heme-binding PAS protein from Escherichia coli is a direct oxygen sensor. Biochemistry 39 (2000) 2685-2691
5. Chang A.L., Tuckerman J.R., Gonzalez G., Mayer R., Weinhouse H., Volman G., et al. Phosphodiesterase A1, a regulator of cellulose synthesis in Acetobacter xylinum, is a heme-based sensor. Biochemistry 40 (2001) 3420-3426
6. Dunham C.M., Dioum E.M., Tuckerman J.R., Gonzalez G., Scott W.G., and Gilles-Gonzalez M.A. A distal arginine in oxygen-sensing heme-PAS domains is essential to ligand binding, signal transduction, and structure. Biochemistry 42 (2003) 7701-7708
7. Key J., and Moffat K. Crystal structures of deoxy and CO-bound bjFixLH reveal details of ligand recognition and signaling. Biochemistry 44 (2005) 4627-4635
8. 2 sensing and ligand discrimination by the FixL heme domain of Bradyrhizobium japonicum. Biochemistry 41 (2002) 12952-12958
9. Balland V., Bouzhir-Sima L., Kiger L., Marden M.C., Vos M.H., Liebl U., and Mattioli T.A. Role of arginine 220 in the oxygen sensor FixL from Bradyrhizobium japonicum. J. Biol. Chem. 280 (2005) 15279-15288
10. 2 sensing: a single convergent structure of the heme moiety is relevant to the downregulation of kinase activity. Biochemistry, in the press.
11. Sciotti M.A., Chanfon A., Hennecke H., and Fischer H.M. Disparate oxygen responsiveness of two regulatory cascades that control expression of symbiotic genes in Bradyrhizobium japonicum. J. Bacteriol. 185 (2003) 5639-5642
12. Preisig O., Zufferey R., Thony-Meyer L., Appleby C.A., and Hennecke H. A high-affinity cbb3-type cytochrome oxidase terminates the symbiosis-specific respiratory chain of Bradyrhizobium japonicum. J. Bacteriol. 178 (1996) 1532-1538
13. Gilles-Gonzalez M.A., Gonzalez G., Perutz M.F., Kiger L., Marden M.C., and Poyart C. Heme-based sensors, exemplified by the kinase FixL, are a new class of heme protein with distinctive ligand binding and autoxidation. Biochemistry 33 (1994) 8067-8073
14. 2, NO, and CO by electrostatic interactions with the bound ligand. J. Biol. Inorg. Chem. 2 (1997) 544-552
15. Carver T.E., Olson J.S., Smerdon S.J., Krzywda S., Wilkinson A.J., Gibson Q.H., et al. Contributions of residue 45(CD3) and heme-6-propionate to the biomolecular and geminate recombination reactions of myoglobin. Biochemistry 30 (1991) 4697-4705
16. Hayashi T., Matsuo T., Hitomi Y., Okawa K., Suzuki A., Shiro Y., et al. Contribution of heme-propionate side-chains to structure and function of myoglobin: chemical approach by artificially created prosthetic groups. J. Inorg. Biochem. 91 (2002) 94-100
17. Gilles-Gonzalez M.A., Ditta G.S., and Helinski D.R. A haemoprotein with kinase activity encoded by the oxygen sensor of Rhizobium meliloti. Nature 350 (1991) 170-172
18. Gilles-Gonzalez M.A., and Gonzalez G. Regulation of the kinase activity of heme protein FixL from the two-component system FixL/FixJ of Rhizobium meliloti. J. Biol. Chem. 268 (1993) 16293-16297
19. Lois A.F., Weinstein M., Ditta G.S., and Helinski D.R. Autophosphorylation and phosphatase activities of the oxygen-sensing protein FixL of Rhizobium meliloti are coordinately regulated by oxygen. J. Biol. Chem. 268 (1993) 4370-4375
20. Tuckerman J.R., Gonzalez G., Dioum E.M., and Gilles-Gonzalez M.A. Ligand and oxidation-state specific regulation of the heme-based oxygen sensor FixL from Sinorhizobium meliloti. Biochemistry 41 (2002) 6170-6177
21. Sousa E.H.S., Gonzalez G., and Gilles-Gonzalez M.-A. Oxygen blocks reaction of the FixL/FixJ complex with ATP, but influences neither FixJ nor ATP binding to FixL. Biochemistry 44 (2005) 15359-15365
22. Koga H., Sagara Y., Yaoi T., Tsujimura M., Nakamura K., Sekimizu K., et al. Essential role of the Arg 112 residue of cytochrome P450cam for electron transfer from reduced putidaredoxin. Fed. Eur. Biochem. Soc. 331 (1993) 109-112
23. Oprea T.I., Hummer G., and Garcia A.E. Identification of a functional water channel in cytochrome P450 enzymes. Proc. Natl Acad. Sci. USA 94 (1997) 2133-2138
24. Qian J., Mills D.A., Geren L., Wang K., Hoganson C.W., Schmidt B., et al. Role of the conserved arginine pair in proton and electron transfer in cytochrome c oxidase. Biochemistry 43 (2004) 5748-5756
25. Seibold S.A., Mills D.A., Ferguson-Miller S., and Cukier R.I. Water chain formation and possible proton pumping routes in Rhodobacter sphaeroides cytochrome c oxidase: a molecular dynamics comparison of the wild-type and R481K mutant. Biochemistry 44 (2005) 10475-10485
26. Branden G., Branden M., Schmidt B., Mills D.A., Ferguson-Miller S., and Brzezinski P. The protonation state of a heme propionate controls electron transfer in cytochrome c oxidase. Biochemistry 44 (2005) 10466-10474
27. Tuckerman J.R., Gonzalez G., and Gilles-Gonzalez M.A. Complexation precedes phosphorylation for two-component regulatory system FixL/FixJ of Sinorhizobium meliloti. J. Mol. Biol. 308 (2001) 449-455
28. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
29. Otwinowski Z., and Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276 (1997) 307-326
30. Murshudov G.N. Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallog. sect. D 53 (1997) 240-255
31. Collaborative Computational Project, Number 4. The CCP4 suite: programs for protein crystallography. Acta Crystallog. sect. D 50 (1994) 760-763
32. Jones T.A., Zou J.Y., Cowan S.W., and Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallog. sect. A 47 (1991) 110-119