Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-l-cysteine in vitro

Toxicology

Volumn 224, Issue 1-2, 2006, Pages 108-118

  Mally, Angela ^a   Walker, Cheryl L ^b   Everitt, Jeffrey I ^c   Dekant, Wolfgang ^a   Vamvakas, Spiros ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF TEXAS   (United States)

^c CIIT CENTERS FOR HEALTH RESEARCH   (United States)

Author keywords

Eker rat; Renal cell tumor; S (dichlorovinyl) l cysteine; Trichloroethene; TSC 2; VHL

Indexed keywords

(DICHLOROVINYL)CYSTEINE; CARCINOGEN; DRUG METABOLITE; TRICHLOROETHYLENE; TUBERIN; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CANCER SUSCEPTIBILITY; CARCINOGENIC ACTIVITY; CARCINOGENICITY; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION; CHEMICAL CARCINOGENESIS; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; EXPOSURE; FEEDING; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; INTOXICATION; KIDNEY CARCINOMA; KIDNEY EPITHELIUM; KIDNEY TUBULE; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; TUMOR SUPPRESSOR GENE;

EID: 33745212267     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.04.036     Document Type: Article

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