-
1
-
-
0025826613
-
Renal involvement in tuberous sclerosis
-
BERNSTEIN, J. and ROBBINS, T.O., Renal involvement in tuberous sclerosis. Ann. N.Y. Acad. Sci., 615, 36-19 (1991).
-
(1991)
Ann. N.Y. Acad. Sci.
, vol.615
, pp. 36-119
-
-
Bernstein, J.1
Robbins, T.O.2
-
2
-
-
0029834567
-
Tuberous sclerosis-associated renal cell carcinoma. Clinical, pathological, and genetic features
-
BJORNSSON, J., SHORT, M.P., KWIATKOWSKI, D.J. and HENSKE E.P., Tuberous sclerosis-associated renal cell carcinoma. Clinical, pathological, and genetic features. Amer. J. Pathol., 149, 1201-1208 (1996).
-
(1996)
Amer. J. Pathol.
, vol.149
, pp. 1201-1208
-
-
Bjornsson, J.1
Short, M.P.2
Kwiatkowski, D.J.3
Henske, E.P.4
-
3
-
-
0001011456
-
A dominant gene for renal adenomas in the rat
-
EKER, R. and MOSSIGE, J., A dominant gene for renal adenomas in the rat. Nature (Lond.) 189, 858-859 (1961).
-
(1961)
Nature (Lond.)
, vol.189
, pp. 858-859
-
-
Eker, R.1
Mossige, J.2
-
4
-
-
0027770784
-
Identification and characterization of the tuberous sclerosis gene on chromosome 16
-
EUROPEAN CHROMOSOME 16 TUBEROUS SCLEROSIS CONSORTIUM, Identification and characterization of the tuberous sclerosis gene on chromosome 16. Cell, 75, 1305-1315 (1993).
-
(1993)
Cell
, vol.75
, pp. 1305-1315
-
-
-
5
-
-
0027954044
-
Mutations of the VHL tumour suppressor gene in renal carcinoma
-
GNARRA, J.R. and 23 OTHERS, Mutations of the VHL tumour suppressor gene in renal carcinoma. Nature (Genet.) 7, 85-90 (1994).
-
(1994)
Nature (Genet.)
, vol.7
, pp. 85-90
-
-
Gnarra, J.R.1
-
6
-
-
0021832510
-
Relationship between serum and histochemical markers for hepatitis B virus and rate of viral integration in hepatocellular carcinomas in Japan
-
HINO, O., KITAGAWA, T. and SUGANO, H., Relationship between serum and histochemical markers for hepatitis B virus and rate of viral integration in hepatocellular carcinomas in Japan. Int. J. Cancer, 35, 5-10 (1985).
-
(1985)
Int. J. Cancer
, vol.35
, pp. 5-10
-
-
Hino, O.1
Kitagawa, T.2
Sugano, H.3
-
7
-
-
0027458433
-
Spontaneous and radiation-induced renal tumors in the Ekerrat model of dominantly inherited cancer
-
HINO, O., KLEIN-SZANTO, A.J.P., FREED, J.J., TESTA, J.R., BROWN, D.Q., VILENSKY, M., YEUNG, R.S., TARTOF, K.D. and KNUDSON, A.G., Spontaneous and radiation-induced renal tumors in the Ekerrat model of dominantly inherited cancer. Proc. Natl. Acad. Sci. (Wash.), 90, 327-331 (1993a).
-
(1993)
Proc. Natl. Acad. Sci. (Wash.)
, vol.90
, pp. 327-331
-
-
Hino, O.1
Klein-Szanto, A.J.P.2
Freed, J.J.3
Testa, J.R.4
Brown, D.Q.5
Vilensky, M.6
Yeung, R.S.7
Tartof, K.D.8
Knudson, A.G.9
-
8
-
-
0028065161
-
The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene
-
HINO, O., KOBAYASHI, T., TSUCHIYA, H., KIKUCHI, Y., KOBAYASHI, E., MITANI, H. and HIRAYAMA, Y., The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene. Biochem. biophys. Res. Comm., 203, 1302-1308 (1994).
-
(1994)
Biochem. Biophys. Res. Comm.
, vol.203
, pp. 1302-1308
-
-
Hino, O.1
Kobayashi, T.2
Tsuchiya, H.3
Kikuchi, Y.4
Kobayashi, E.5
Mitani, H.6
Hirayama, Y.7
-
9
-
-
0027433684
-
A novel renal cell carcinoma susceptibility gene maps on chromosome 10 in the Eker rat
-
HINO, O., MITANI, H., NISHIZAWA, M., KATSUYAMA, H., KOBAYASHI, E. and HIRAYAMA, Y., A novel renal cell carcinoma susceptibility gene maps on chromosome 10 in the Eker rat. Jpn. J. Cancer Res., 84, 1106-1109 (1993b).
-
(1993)
Jpn. J. Cancer Res.
, vol.84
, pp. 1106-1109
-
-
Hino, O.1
Mitani, H.2
Nishizawa, M.3
Katsuyama, H.4
Kobayashi, E.5
Hirayama, Y.6
-
10
-
-
0024571438
-
Atypical cysts and carcinomas of the kidneys in the phacomatoses
-
IBRAHIM, R.E., WEINBERG, D.S. and WEIDNER, N., Atypical cysts and carcinomas of the kidneys in the phacomatoses. Cancer, 63, 148-157 (1989).
-
(1989)
Cancer
, vol.63
, pp. 148-157
-
-
Ibrahim, R.E.1
Weinberg, D.S.2
Weidner, N.3
-
11
-
-
0028270758
-
Spontaneous renal cell tumors in Long-Evans Cinnamon rats
-
IZUMI, K., KITAURA, K., CHONE, Y., TATE, H., NAKAGAWA, T., SUZUKI, Y. and MATSUMOTO, K., Spontaneous renal cell tumors in Long-Evans Cinnamon rats. Jpn. J. Cancer Res., 85, 563-566 (1994).
-
(1994)
Jpn. J. Cancer Res.
, vol.85
, pp. 563-566
-
-
Izumi, K.1
Kitaura, K.2
Chone, Y.3
Tate, H.4
Nakagawa, T.5
Suzuki, Y.6
Matsumoto, K.7
-
12
-
-
0029814436
-
Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region
-
JIN, F., WIENECKE, R., XIAO, G.-H., MAIZE, J.C., DECLUE, J.E. and YEUNG, R.S., Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region. Proc. nat. Acad. Sci.(Wash.), 93, 9154-9159 (1996).
-
(1996)
Proc. Nat. Acad. Sci.(Wash.)
, vol.93
, pp. 9154-9159
-
-
Jin, F.1
Wienecke, R.2
Xiao, G.-H.3
Maize, J.C.4
Declue, J.E.5
Yeung, R.S.6
-
13
-
-
0028815637
-
Cloning of the rat homologue of the von Hippel-Lindau tumor suppressor gene and its non-somatic mutation in rat renal cell carcinomas
-
KIKUCHI, Y., KOBAYASHI, E., NISHIZAWA, M., HAMAZAKI, S., OKADA, S. and HINO, O., Cloning of the rat homologue of the von Hippel-Lindau tumor suppressor gene and its non-somatic mutation in rat renal cell carcinomas. Jpn. J. Cancer Res., 86, 905-909 (1995).
-
(1995)
Jpn. J. Cancer Res.
, vol.86
, pp. 905-909
-
-
Kikuchi, Y.1
Kobayashi, E.2
Nishizawa, M.3
Hamazaki, S.4
Okada, S.5
Hino, O.6
-
14
-
-
0028830856
-
A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer
-
KOBAYASHI, T., HIRAYAMA, Y., KOBAYASHI, E., KUBO, Y. and HINO, O., A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer. Nature (Genet.), 9, 70-74 (1995).
-
(1995)
Nature (Genet.)
, vol.9
, pp. 70-74
-
-
Kobayashi, T.1
Hirayama, Y.2
Kobayashi, E.3
Kubo, Y.4
Hino, O.5
-
15
-
-
0030929668
-
Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-type Tsc2 gene
-
KOBAYASHI, T., MITANI, H., TAKAHASHI, R., HIRABAYASHI, M., UEDA, M., TAMURA, H. and HINO, O., Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-type Tsc2 gene. Proc. nat. Acad. Sci. (Wash.), 94, 3990-3993 (1997a).
-
(1997)
Proc. Nat. Acad. Sci. (Wash.)
, vol.94
, pp. 3990-3993
-
-
Kobayashi, T.1
Mitani, H.2
Takahashi, R.3
Hirabayashi, M.4
Ueda, M.5
Tamura, H.6
Hino, O.7
-
16
-
-
0031205937
-
Identification of a leader exon and a core promoter for the rat tuberous sclerosis 2 (Tsc2) gene and structural comparison with the human homologue
-
KOBAYASHI, T., URAKAMI, S., CHEADLE, J.P., ASPINWALL, R., HARRIS, P., SAMPSON, J.R. and HINO, O., Identification of a leader exon and a core promoter for the rat tuberous sclerosis 2 (Tsc2) gene and structural comparison with the human homologue. Mamm. Genome, 8, 554-558 (1997b).
-
(1997)
Mamm. Genome
, vol.8
, pp. 554-558
-
-
Kobayashi, T.1
Urakami, S.2
Cheadle, J.P.3
Aspinwall, R.4
Harris, P.5
Sampson, J.R.6
Hino, O.7
-
17
-
-
0030934101
-
Intragenic Tsc2 somatic mutations as Knudson's second hit in spontaneous and chemically induced renal carcinomas in the Eker rat model
-
KOBAYASHI, T., URAKAMI, S., HIRAYAMA, Y., YAMAMOTO, T., NISHIZAWA, M., TAKAHARA, T., KUBO, Y., and HINO, O., Intragenic Tsc2 somatic mutations as Knudson's second hit in spontaneous and chemically induced renal carcinomas in the Eker rat model. Jpn. J. Cancer Res., 88, 254-261 (1997c).
-
(1997)
Jpn. J. Cancer Res.
, vol.88
, pp. 254-261
-
-
Kobayashi, T.1
Urakami, S.2
Hirayama, Y.3
Yamamoto, T.4
Nishizawa, M.5
Takahara, T.6
Kubo, Y.7
Hino, O.8
-
18
-
-
0028913673
-
Early detection of Knudson's two-hits in preneoplastic renal cells of the Eker rat model by the laser microdissection procedure
-
KUBO, Y., KLIMEK, F., KIKUCHI, Y., BANNASCH, P. and HINO, O., Early detection of Knudson's two-hits in preneoplastic renal cells of the Eker rat model by the laser microdissection procedure. Cancer Res., 55, 989-990 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 989-990
-
-
Kubo, Y.1
Klimek, F.2
Kikuchi, Y.3
Bannasch, P.4
Hino, O.5
-
19
-
-
0028228998
-
Allelic Toss at the predisposing gene locus in spontaneous and chemically induced renal cell carcinomas in the Eker rat
-
KUBO, Y., MITANI, H. and HINO, O., Allelic Toss at the predisposing gene locus in spontaneous and chemically induced renal cell carcinomas in the Eker rat. Cancer Res., 54, 2633-2635 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 2633-2635
-
-
Kubo, Y.1
Mitani, H.2
Hino, O.3
-
20
-
-
0027240519
-
Identification of the von Hippel-Lindau tumor-suppressor gene
-
LATIF, F. and 30 OTHERS, Identification of the von Hippel-Lindau tumor-suppressor gene. Science, 260, 1317-1320 (1993).
-
(1993)
Science
, vol.260
, pp. 1317-1320
-
-
Latif, F.1
-
21
-
-
0030090948
-
Expression and differential splicing of the mouse Tsc2 homolog
-
OLSSON, P.C., SCHOFIELD, J.N., EDWARDS, Y.H. and FRISCHAUF, A.M., Expression and differential splicing of the mouse Tsc2 homolog. Mamm. Genome, 7, 212-215 (1996).
-
(1996)
Mamm. Genome
, vol.7
, pp. 212-215
-
-
Olsson, P.C.1
Schofield, J.N.2
Edwards, Y.H.3
Frischauf, A.M.4
-
22
-
-
0030044323
-
Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells
-
ORIMOTO, K., TSUCHIYA, H., KOBAYASHI, T., MATSUDA, T. and HINO, O., Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells. Biochem. biophys. Res. Comm., 219, 70-75 (1996).
-
(1996)
Biochem. Biophys. Res. Comm.
, vol.219
, pp. 70-75
-
-
Orimoto, K.1
Tsuchiya, H.2
Kobayashi, T.3
Matsuda, T.4
Hino, O.5
-
23
-
-
0001882366
-
Spontaneous hepatitis in an inbred strain of Long-Evans rats
-
SASAKI, M., YOSHIDA, M.C., KAGAMI, K., TAKEICHI, N., KOBAYASHI, H., DEMPO, K. and MORI, M., Spontaneous hepatitis in an inbred strain of Long-Evans rats. Rat Newslett., 14, 4-6 (1985).
-
(1985)
Rat Newslett.
, vol.14
, pp. 4-6
-
-
Sasaki, M.1
Yoshida, M.C.2
Kagami, K.3
Takeichi, N.4
Kobayashi, H.5
Dempo, K.6
Mori, M.7
-
24
-
-
17344381429
-
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
-
SCHMIDT, L. and 34 OTHERS, Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nature (Genet.), 16, 68-73 (1997).
-
(1997)
Nature (Genet.)
, vol.16
, pp. 68-73
-
-
Schmidt, L.1
-
25
-
-
0030842661
-
Polymerase chain reaction-single-strand conformation polymorphism analysis for the VHL gene in chemically induced kidney tumors of rats using intron-derived primers
-
SHIAO, Y.H., DIWAN, B.A., PERANTONI, A.O., CALVERT, R.J., ZBAR, B., LERMAN, M.I. and RICE, J.M., Polymerase chain reaction-single-strand conformation polymorphism analysis for the VHL gene in chemically induced kidney tumors of rats using intron-derived primers. Mol. Carcinogenesis, 19, 230-235 (1997).
-
(1997)
Mol. Carcinogenesis
, vol.19
, pp. 230-235
-
-
Shiao, Y.H.1
Diwan, B.A.2
Perantoni, A.O.3
Calvert, R.J.4
Zbar, B.5
Lerman, M.I.6
Rice, J.M.7
-
26
-
-
0028235907
-
Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary humanrenal cell carcinomas
-
SHUIN, T., KONDO, K., TORIGOE, S., KISHIDA, T., KUBOTA, Y., HOSAKA, M., NAGASHIMA, Y., KITAMURA, H., LATIF, F., ZBAR, B., LERMAN, M.I. and YAO, M., Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary humanrenal cell carcinomas. Cancer Res., 54, 2852-2855 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 2852-2855
-
-
Shuin, T.1
Kondo, K.2
Torigoe, S.3
Kishida, T.4
Kubota, Y.5
Hosaka, M.6
Nagashima, Y.7
Kitamura, H.8
Latif, F.9
Zbar, B.10
Lerman, M.I.11
Yao, M.12
-
27
-
-
0030879277
-
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34
-
SLEGTENHORST, M. and 40 OTHERS, Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science, 277, 805-808 (1997).
-
(1997)
Science
, vol.277
, pp. 805-808
-
-
Slegtenhorst, M.1
-
28
-
-
0030064915
-
Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model
-
TSUCHIYA, H., ORIMOTO, K., KOBAYASHI, T. and HINO, O., Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model. Cancer Res., 56, 429-433 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 429-433
-
-
Tsuchiya, H.1
Orimoto, K.2
Kobayashi, T.3
Hino, O.4
-
29
-
-
0030951972
-
Somatic mutation of the tuberous sclerosis (Tsc2) tumor suppressor gene in chemically induced rat renal carcinoma cell
-
URAKAMI, S., TOKUZEN, R., TSUDA, H., IGAWA, M. and HINO, O., Somatic mutation of the tuberous sclerosis (Tsc2) tumor suppressor gene in chemically induced rat renal carcinoma cell. J. Urol., 158, 275-278 (1997).
-
(1997)
J. Urol.
, vol.158
, pp. 275-278
-
-
Urakami, S.1
Tokuzen, R.2
Tsuda, H.3
Igawa, M.4
Hino, O.5
-
30
-
-
0027986502
-
Germline mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma
-
WHALEY, J.M., NAGLICH, J., GELBERT, L., HSIA, Y.E., LAMIELL, J.M., GRAN, J.S., COLLINS, D., NEUMANN, H.P.H., LAIDLAW, J., LI, F., KLEIN-SZANTO, A.J.P., SEIZINGER, B.R. and KLEY, N., Germline mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma. Amer. J. hum. Genet., 55, 1092-1102 (1994).
-
(1994)
Amer. J. Hum. Genet.
, vol.55
, pp. 1092-1102
-
-
Whaley, J.M.1
Naglich, J.2
Gelbert, L.3
Hsia, Y.E.4
Lamiell, J.M.5
Gran, J.S.6
Collins, D.7
Neumann, H.P.H.8
Laidlaw, J.9
Li, F.10
Klein-Szanto, A.J.P.11
Seizinger, B.R.12
Kley, N.13
-
31
-
-
0029021621
-
Identification of tuberin, the tuberous sclerosis-2 product
-
WIENECKE, R., KÖNIG, A. and DECLUE, J.E., Identification of tuberin, the tuberous sclerosis-2 product. J. biol. Chem., 270, 16409-16414 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16409-16414
-
-
Wienecke, R.1
König, A.2
Declue, J.E.3
-
32
-
-
0030972969
-
The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis
-
XIAO, G.-H., SHOARINEJAD, F., JIN, F., GOLEMIS, E.A. and YEUNG, R.S., The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis. J. biol. Chem., 272, 6097-6100 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6097-6100
-
-
Xiao, G.-H.1
Shoarinejad, F.2
Jin, F.3
Golemis, E.A.4
Yeung, R.S.5
-
33
-
-
0027273337
-
Elevated level of 8-hydroxydeoxyguanosine in DNA of liver, kidneys, and brain of Long-Evans Cinnamon rats
-
YAMAMOTO, F., KASAI, H., TOGASHI, Y., TAKEICHI, N., HORI, T. and NISHIMURA, S., Elevated level of 8-hydroxydeoxyguanosine in DNA of liver, kidneys, and brain of Long-Evans Cinnamon rats. Jpn. J. Cancer Res., 84, 508-511 (1993).
-
(1993)
Jpn. J. Cancer Res.
, vol.84
, pp. 508-511
-
-
Yamamoto, F.1
Kasai, H.2
Togashi, Y.3
Takeichi, N.4
Hori, T.5
Nishimura, S.6
-
34
-
-
0029294112
-
Familial renal cell carcinoma: Review of recent molecular genetics
-
YAO, M. and SHUIN, T., Familial renal cell carcinoma: review of recent molecular genetics. Int. J. Urol., 2, 61-70 (1995).
-
(1995)
Int. J. Urol.
, vol.2
, pp. 61-70
-
-
Yao, M.1
Shuin, T.2
-
35
-
-
0027996238
-
Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis (TSC) 2 gene
-
YEUNG, R.S., XIAO, G.-H., JIN, F., LEE, W.-C., TESTA, J.R. and KNUDSON, A.G., Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis (TSC) 2 gene. Proc. natl. Acad. Sci. (Wash.), 91, 11413-11416 (1994).
-
(1994)
Proc. Natl. Acad. Sci. (Wash.)
, vol.91
, pp. 11413-11416
-
-
Yeung, R.S.1
Xiao, G.-H.2
Jin, F.3
Lee, W.-C.4
Testa, J.R.5
Knudson, A.G.6
|