Patterns of chloroform-induced regenerative cell proliferation in BDF1 mice correlate with organ specificity and dose-response of tumor formation

Carcinogenesis

Volumn 19, Issue 1, 1998, Pages 187-193

  Templin, Michael V ^a,b   Constan, Alexander A ^a   Wolf, Douglas C ^a   Wong, Brian A ^a   Butterworth, Byron E ^a  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CHLOROFORM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CARCINOGENICITY; CELL DEGENERATION; CELL LABELING; CELL PROLIFERATION; CELL REGENERATION; CELL VACUOLE; CONTROLLED STUDY; DOSE RESPONSE; IMMUNOHISTOCHEMISTRY; KIDNEY ADENOMA; KIDNEY CARCINOMA; KIDNEY TUBULE; KIDNEY TUMOR; LABELING INDEX; LIVER CELL; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOMA; ANIMALS; BODY WEIGHT; CARCINOGENS; CARCINOMA; CELL DIVISION; CHLOROFORM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LIVER; LIVER NEOPLASMS; LIVER REGENERATION; MALE; MICE; ORGAN SIZE; SEX CHARACTERISTICS; TIME FACTORS;

EID: 0031869955     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.1.187     Document Type: Article

References (45)

1. Craun, G.F. (ed.) (1993) Safety of Water Disinfection: Balancing Chemical and Microbial Risks. ILSI Press, Washington, DC.
2. Symons, J.M., Bellar, T.A., Carswell, J.K. et al. (1975). National organics reconnaissance survey for halogenated organics. J. Am. Water Works Assoc., 67, 634.
3. Butler, E.C.V. and Dal Pont, G. (1992) Liquid chromatography electrochemistry procedure for the determination of chlorophenolic compounds in pulp mill effluents and receiving waters. J. Chomatogr., 609, 113-123.
4. Singh, H.B., Salas, L.J. and Stiles, R.E. (1982) Distribution of selected gaseous organic mutagens and suspect carcinogens in ambient air. Environ. Sci. Technol., 16, 872-880.
5. Aggazzotti, G., Fantuzzi, G., Tartoni, P.L. and Predieri, G. (1990) Plasma chloroform concentrations in swimmers using indoor swimming pools. Arch. Environ. Health, 45, 175-179.
6. Jo, W.K., Weisel, C.P. and Lioy, P.J. (1990) Routes of chloroform exposure and body burden from showering with chlorinated tap water. Risk Anal., 10, 575-580.
7. Eschenbrenner, A.B. and Miller, E. (1945) Induction of hepatomas in mice by repeated oral administration of chloroform with observations on sex differences. J. Natl Cancer Inst., 2, 251-255.
8. Reitz, R.H., Mendrala, A.L., Corley, R.A., Quast, J.F., Gargas, M.L., Andersen, M.E., Staats, D.A. and Conolly, R.B. (1990) Estimating the risk of liver cancer associated with human exposures to chloroform. Toxicol. Appl. Pharmacol., 105, 443-459.
9. Butterworth, B.E., Conolly, R.B. and Morgan, K.T. (1995) A strategy for establishing mode of action of chemical carcinogens as a guide for approaches to risk assessments. Cancer Lett., 93, 129-146.
10. Butterworth, B.E., Popp, J.A., Conolly, R.B. and Goldsworthy, T.L. (1992) Chemically-induced cell proliferation in carcinogenesis. In H. Vainio, P.N. Magee, D.B. McGregor and A.J. McMichael (eds) Mechanisms of Carcinogenesis in Risk Identification. IARC Scientific Publication No. 116, IARC, Lyons, France, pp. 279-305.
11. Walker, V.E., Fennell, T.R., Boucheron, J.A., Fedtke, N., Ciroussel, F. and Swenberg, J.A. (1990) Macromolecular adducts of ethylene oxide: a literature review and a time-course study on the formation of 7-(2-hydroxyethyl)guanine following exposures of rats by inhalation. Mutat. Res., 233, 151-164.
12. 1 mice. Environ. Mol. Mutagen., 23, 132-136.
13. 1 mice following chloroform inhalation. Env. Mol. Mutagen., 29, 49.
14. International Programme on Chemical Safety. (1994) Chloroform, Environmental Health Criteria 163, World Health Organization, Geneva.
15. National Cancer Institute (NCI) (1976) Carcinogenesis Bioassay of Chloroform. Bethesda, MD, National Tech. Inform. Service No. PB264018/AS.
16. 1 mice: Comparison of administration by gavage in corn oil versus ad libitum in drinking water. Fund. Appl. Toxicol., 22, 90-102.
17. 1 mice given chloroform by gavage. Fund. Appl. Toxicol., 23, 537-543.
18. 1 mice. Fund. Appl. Toxicol., 5, 760-769.
19. Templin, M.V., Jamison, K.C., Wolf, D.C., Morgan, K.T. and Butterworth, B.E. (1996a) Comparison of chloroform-induced toxicity in the kidneys, liver and nasal passages of male Osborne-Mendel and F-344 rats. Cancer Lett., 104, 71-78.
20. 1 mice (abstract). Proceedings of the Fifty-third Annual Meeting of the Japanese Cancer Association.
21. Matsushima, T. (1994). An inhalation carcinogenesis study of chloroform. Initial Report. Japan Bioassay Laboratory, Japan Industrial Safety and Health Association, 2445 Ohshibahara Hirasawa Hando Kanagawa, 257 Japan.
22. Templin, M.V., Larson, J.L., Butterworth, B.E., Jamison, K., Wong, B.A. and Wolf, D.C. (1996) A 90-day chloroform inhalation study in F-344 rats: Profile of toxicity and relevance to cancer studies. Fund. Appl. Toxicol., 32, 109-125.
23. 1 mice. Cancer Lett., 108, 225-231.
24. National Institutes of Health (NIH) (1985) Guide for the Care and Use of Laboratory Animals. United States Department of Health and Human Services, Public Health Service, NIH Publication No. 86-23.
25. Wong, B.A. and Moss, O.R. (1996) Application of a building management system to automate a 90-day chloroform inhalation study. Toxicol. Meth., 6, 53-64.
26. 3H]thymidine administered by injection or osmotic pump. Carcinogenesis, 11, 2245-2251.
27. 1 mice: Implications for cancer risk assessment. Fund. Appl. Toxicol., 30, 118-137.
28. 1 mice and male F-344 rats. Fund. Appl. Toxicol., 22, 431-446.
29. Williams, D.A. (1971). A test for differences between treatment means when several dose levels are compared with a zero dose control. Biometrics, 27, 103-117.
30. Williams, D.A. (1972) The comparison of several dose levels with a zero dose control. Biometrics, 28, 519-531.
31. 1 mice. Toxicologist, 36, 135.
32. Smith, J.H., Maita, K., Sleight, S. and Hook, J.B. (1984) Effect of sex hormone status on chloroform nephrotoxicity and renal mixed function oxidases in mice. Toxicology, 30, 305-316.
33. Dietrich, D.R. and Swenberg, J.A. (1991) The presence of α2u-globulin is necessary for d-limonene promotion of male rat kidney tumors. Cancer Res., 51, 3512-3521.
34. Short, B.G., Burnett, V.L., Cox, M.G., Bus, J.S. and Swenberg, J.A. (1987) Site-specific renal cytotoxicity and cell proliferation in male rats exposed to petroleum hydrocarbons. Lab. Invest., 57, 564-577.
35. Grasso, P. and Hardy, J. (1975) Strain differences in natural incidence and response to carcinogens. In W.H. Butler and P.M. Newberne (eds) Mouse Hepatic Neoplasia. Elsevier, NY, pp. 111-131.
36. Drinkwater, N.R. (1994) Genetic control of hepatocarcinogenesis in C3H mice. Drug Metabol. Rev., 26, 201-208.
37. Lee, G.-H. and Drinkwater, N.R. (1995) Hepatocarcinogenesis in BXH recombinant inbred strains of mice: Analysis of diverse phenotypic effects of the hepatocarcinogen sensitivity loci. Mol. Carcinogenesis, 14, 190-197.
38. Hill, R.N., Clemens, T.L., Lui, D.K. and Vesell, E.S. (1975) Genetic control of chloroform toxicity in mice. Science, 190, 159-161.
39. Clemens, T.L., Hill, R.N., Bullock, L.P., Johnson, W.D., Sultatos, L.G. and Vesell, E.S (1979) Chloroform toxicity in the mouse: Role of genetic factors and steroids. Toxicol. Appl. Pharmacol., 48, 117-130.
40. Ahmadizadeh, M., Echt, R., Kuo, C. and Hook, J.B. (1984) Sex and strain differences in mouse kidney: Bowman's capsule morphology and susceptibility to chloroform. Toxicol. Lett., 20, 161-172.
41. Andelman, J.B. (1985) Human exposures to volatile halogenated organic chemicals in indoor and outdoor air. Environ. Health Perspect., 62, 313-318.
42. United States Environmental Protection Agency (1986) Guidelines for Carcinogen Risk Assessment. Washington, DC.
43. United States Environmental Protection Agency (1985) Health Assessment Document for Chloroform, EPA/600/8-84/004F.
44. United States Environmental Protection Agency (1995) Integrated Risk Information System (IRIS) Database, June 12, 1995.
45. United States Environmental Protection Agency (1996) Proposed guidelines for carcinogen risk assessment; Notice. Fed. Reg. 61(79): 17960-18011. April 23.