Engineering responsiveness to cell culture stresses: Growth arrest and DNA damage gene 153 (GADD153) and the unfolded protein response (UPR) in NS0 myeloma cells

Biotechnology and Bioengineering

Volumn 94, Issue 3, 2006, Pages 514-521

  Cudna, Renata E ^a   Dickson, Alan J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

C EBP homologous protein (CHOP); ER stress; Small interfering RNA (siRNA)

Indexed keywords

CELL CULTURE; CELL MEMBRANES; DNA; GROWTH KINETICS; PROTEINS; RNA;

C/EBP HOMOLOGOUS PROTEIN (CHOP); ENDOPLASMIC RETICULUM (ER) STRESS; SMALL INTERFERING RNA (SIRNA); UNFOLDED PROTEIN RESPONSE (UPR);

GENETIC ENGINEERING;

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; TUNICAMYCIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE EXPRESSION; MOLECULAR CLONING; MOUSE; MYELOMA CELL; NONHUMAN; PROTEIN ENGINEERING; PROTEIN FOLDING; SENSITIVITY ANALYSIS; STRESS;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; ENDOPLASMIC RETICULUM; MICE; PROTEIN FOLDING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP;

EID: 33745202273     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.20861     Document Type: Article

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